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      • KCI등재

        Methodology of uncertainty analysis prediction based on multi-well data fusion

        Huan Jie Zhang,Kai Wei,Alain P. Tchameni,G. Ben-Kane 한국자원공학회 2018 Geosystem engineering Vol.21 No.3

        During drilling activities, geological parameters of a well to be drilled (target well) can be predicted within a limited interval based on multi-well data fusion which aims at ensuring a drilling safety, enhancement of drilling efficiency, reduction of drilling cost as well as acquiring accurate measurements in respect to Oil and Gas protection layers. This work presents a method of uncertainty analysis prediction of pressures using fusion data (formation pressures) from adjacent multi-well. The Eaton method, effective stress theory, and mathematical confidence interval were the various methods used to establish the formation pressure matrix of the target well. The results revealed that due to the complexity and variability of the formations, data interpretation errors of the geological parameters were inevitable. Therefore, the probability density distribution function was established through stratigraphy, probability statistics, and information diffusion. Moreover, the real value of the wells’ formation pressure (target well) was within the distribution interval of multi-well data fusion. Hence, the developed method cannot only effectively reduce the interval of geological parameter of the target well but also enhance the accuracy of parameters prediction.

      • Risk Factors for Cervical Cancer in Rural Areas of Wuhan China: a Matched Case-control Study

        Zhang, Bin,Zhou, Ai-Fen,Zhu, Chang-Cai,Zhang, Ling,Xiang, Bing,Chen, Zhong,Hu, Rong-Hua,Zhang, Ya-Qi,Qiu, Lin,Zhang, Yi-Ming,Xiong, Chao-Du,Du, Yu-Kai,Shi, Yu-Qin Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.12

        Cervical cancer is a serious public health problem in developing countries. We investigated possible risk factors for cervical cancer in rural areas of Wuhan China using a matched case-control study with 33 women diagnosed with cervical cancer and 132 healthy women selected from the same area as matched controls. A questionnaire, which included questions about general demography conditions, environmental and genetic factors, the first sexual intercourse, first marriage age, age at first pregnancy, pregnancy first child's age, female personal health history, social psychological factors, dietary habits, smoking and alcohol status and other living habits was presented to all participants. At the same time, HPV infection of every participant was examined in laboratory testing. Results showed HPV infection (P<0.000, OR=23.4) and pregnancy first child's age (P<0.000, OR=13.1) to be risk factors for cervical cancer. Menopause (P=0.003, OR=0.073) was a protective factor against cervical cancer. However, there was no indication of associations of environmental (drinking water, insecticide, disinfectant) genetic (cancer family history), or life-style factors (smoking status, alcohol status, physical training, sleep quality), including dietary habits (intake of fruit and vegetable, meat, fried food, bean products and pickled food) or social psychological factors with cervical cancer. The results suggest that the risk of cervical cancer in Chinese rural women may be associated with HPV infection, menopause and the pregnancy first child's age.

      • KCI등재

        Adaptive Dynamic Programming for Minimal Energy Control with Guaranteed Convergence Rate of Linear Systems

        Kai Zhang,Suoliang Ge,Yuling Ge 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.12

        The traditional linear quadratic optimal control can be summarized as finding the state feedback controller, so that the closed-loop system is stable and the performance index is minimum. And it is well known that the solution of the linear quadratic optimal control problem can be obtained by algebraic Riccati equation (ARE) with the standard assumptions. However, results developed for the raditional linear quadratic optimal control problem cannot be directly applied to solve the problem of minimal energy control with guaranteed convergence rate (MECGCR), because the standard assumptions cannot be satisfied in the MECGCR problem. In this paper, we mainly consider the problem of MECGCR and prove that ARE can be applied to solve the MECGCR problem under some conditions. Furthermore, with the assumption that the system dynamics is unknown, we propose a policy iteration (PI) based adaptive dynamic programming (ADP) algorithm to iteratively solve the ARE using the online information of state and input, without requiring the a priori knowledge of the system matrices. Finally, a numerical example is worked out to show the effectiveness of the proposed approach.

      • SCISCIESCOPUS

        Guaranteeing Deadlines for Inter-Data Center Transfers

        Zhang, Hong,Chen, Kai,Bai, Wei,Han, Dongsu,Tian, Chen,Wang, Hao,Guan, Haibing,Zhang, Ming Institute of Electrical and Electronics Engineers, 2017 IEEE/ACM transactions on networking Vol.25 No.1

        <P>Inter-data center wide area networks (inter-DC WANs) carry a significant amount of data transfers that require to be completed within certain time periods, or deadlines. However, very little work has been done to guarantee such deadlines. The crux is that the current inter-DC WAN lacks an interface for users to specify their transfer deadlines and a mechanism for provider to ensure the completion while maintaining high WAN utilization. In this paper, we address the problem by introducing a deadline-based network abstraction (DNA) for inter-DC WANs. DNA allows users to explicitly specify the amount of data to be delivered and the deadline by which it has to be completed. The malleability of DNA provides flexibility in resource allocation. Based on this, we develop a system called Amoeba that implements DNA. Our simulations and test bed experiments show that Amoeba, by harnessing DNA's malleability, accommodates 15% more user requests with deadlines, while achieving 60% higher WAN utilization than prior solutions.</P>

      • An Optimized Hierarchical Handoff Method with Mobile IP and SIP

        Kai Zhang(장개),Ji-Gong(공길),Yoonhwan Park(박윤환),Kisung Yu(유기성),Gihwan Cho(조기환) 한국멀티미디어학회 2008 한국멀티미디어학회 학술발표논문집 Vol.2008 No.1

        In the 4 generation(4G) wireless network, mobility management can be effectively achieved by applying Mobile IP(MIP) and the Session Initiation Protocol(SIP) in cooperatively. However, an important and challenging issue is the handoff management in this architecture. In this paper, we present an optimized handoff method with MIP and SIP. Two mechanisms are proposed to resolve micro-mobility, along with same domain mobility. Micro-mobility handoff manages movements in the one area, while same domain mobility handoff manages movements between two neighboring are as. This method makes use of a retransmission for micro-mobility, and multicasting to re-establish a traffic flow for same domain mobility.

      • KCI등재

        Preparation and Performance Study of COS/PEI@PolyI:C/OVA Nanocomposite Using the Blend System of Chitooligosaccharide and Polyethyleneimine as a Drug Carrier

        Kai Zhang,Qian Sun,Xiaoyu Bai,Peng Liu,Zijian Lyu,Qiuhong Li,Aixiang Li 한국고분자학회 2021 Macromolecular Research Vol.29 No.11

        The blending system of chitooligosaccharide (COS) and polyethyleneimine (PEI) was studied as a drug carrier for tumor treatment. Nanoparticles COS/ PEI-PolyI:C-OVA-x (CP-P-O-x) (x=1, 2, 3) were prepared by electrostatic self-assembly of COS and PEI with the immune enhancing drug PolyI:C and the mimic antigen ovalbumin (OVA) using different feeding methods. The results showed that the nanoparticle solution could be stable only when the concentration of the added PEI was above 5.0% w/w. PolyI:C could be coated well and protected from nuclease degradation. The OVA encapsulation efficiency was above 75%. The results of cell viability experiments showed that the blend of COS and PEI had low cytotoxicity. The CP-P-O-1 had a suitable particle size, which was easy to be absorbed and expressed by cells. The results of in vitro immunization showed that due to the addition of PolyI:C, whether OVA was loaded on the inside or on the surface, nanoparticles significantly promoted the secretion of cytokines mouse tumor necrosis factor α (TNF-α) and mouse interferon-γ (IFN-γ). The feeding method mainly had a greater impact on the morphology and size of the nanoparticles, and had little effect on solution stability, OVA encapsulation efficiency, binding ability with PolyI:C, resistance to nuclease degradation and immune performance. CP-P-O-x prepared by the blend system of COS and PEI will be a potential candidate for tumor treatment.

      • KCI등재후보

        Real Time Related Key Attack on Hummingbird-2

        ( Kai Zhang ),( Lin Ding ),( Junzhi Li ),( Jie Guan ) 한국인터넷정보학회 2012 KSII Transactions on Internet and Information Syst Vol.6 No.8

        Hummingbird is a lightweight encryption and message authentication primitive published in RISC`09 and WLC`10. In FSE`11, Markku-Juhani O.Saarinen presented a differential divide-and-conquer method which has complexity upper bounded by 2<sup>64</sup> operations and requires processing of few megabytes of chosen messages under two related nonces (IVs). The improved version, Hummingbird-2, was presented in RFIDSec 2011. Based on the idea of differential collision, this paper discovers some weaknesses of the round function WD16. Combining with the simple key loading algorithm, a related-key chosen-IV attack which can recover the full secret key is proposed. Under 15 pairs of related keys, the 128 bit initial key can be recovered, requiring 2<sup>27</sup> chosen IV and the computational complexity is O(2<sup>27</sup>). In average, the attack needs several minutes to recover the full 128-bit secret key on a PC. The experimental result corroborates our attack. The result shows that the Hummingbird-2 cipher can`t resist related key attack.

      • KCI등재

        The MAP Kinase Kinase Gene AbSte7 Regulates Multiple Aspects of Alternaria brassicicola Pathogenesis

        Kai Lu,Min Zhang,Ran Yang,Min Zhang,Qinjun Guo,Kwang-Hyun Baek,Hou-Juan Xu 한국식물병리학회 2019 Plant Pathology Journal Vol.35 No.2

        Mitogen-activated protein kinase (MAPK) cascades in fungi are ubiquitously conserved signaling pathways that regulate stress responses, vegetative growth, pathogenicity, and many other developmental processes. Previously, we reported that the AbSte7 gene, which encodes a mitogen-activated protein kinase kinase (MAPKK) in Alternaria brassicicola, plays a central role in pathogenicity against host cabbage plants. In this research, we further characterized the role of AbSte7 in the pathogenicity of this fungus using ΔAbSte7 mutants. Disruption of the AbSte7 gene of A. brassicicola reduced accumulation of metabolites toxic to the host plant in liquid culture media. The ΔAbSte7 mutants could not efficiently detoxify cruciferous phytoalexin brassinin, possibly due to reduced expression of the brassinin hydrolase gene involved in detoxifying brassinin. Disruption of the AbSte7 gene also severely impaired fungal detoxification of reactive oxygen species. AbSte7 gene disruption reduced the enzymatic activity of cell walldegrading enzymes, including cellulase, β-glucosidase, pectin methylesterase, polymethyl-galacturonase, and polygalacturonic acid transeliminase, during host plant infection. Altogether, the data strongly suggest the MAPKK gene AbSte7 plays a pivotal role in A. brassicicola during host infection by regulating multiple steps, and thus increasing pathogenicity and inhibiting host defenses.

      • KCI등재

        Effect of gold nanoparticles on the performances of the phosphorescent organic light-emitting devices

        Kai Xu,Yang Li,Wei Zhang,Letian Zhang,Wenfa Xie 한국물리학회 2014 Current Applied Physics Vol.14 No.1

        Gold nanoparticles (GNPs) on the performance of the phosphorescent organic light-emitting devices (OLEDs) were investigated. The green phosphorescent OLEDs with GNPs incorporated in hole transporting layer (HTL) or hole blocking layer (HBL) were fabricated using thermal evaporation technique. The results indicated that the performance of the OLEDs with GNPs were dependent on the position of the GNPs. The optimized device with GNPs in HBL shows enhanced current efficiency and reduced efficiency roll-off. However, the efficiency of the device with GNPs in HTL was decreased. The detailed physical mechanism is investigated in order to unveil such difference.

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