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요추 수술 예정 환자에서 실시한 선택적 신경근 차단술의 5년 추시 결과
심대무(Dae Moo Shim),김태균(Tae Kyun Kim),오성균(Sung Kyun Oh),최윤홍(Yun Hong Choi),이석중(Suk Jung Lee) 대한정형외과학회 2009 대한정형외과학회지 Vol.44 No.1
목적: 하지 방사통을 호소하는 환자의 수술 준비 과정에서 선택적 척추 신경근 차단술을 실시하고, 그 효과가 얼마나 오래 유지되는지를 알아 보고자 5년 이상 추시된 환자를 대상으로 분석하여 그 결과를 보고 하고자 한다. 대상 및 방법: 2000년 1월에서 2000년 12월까지 하지 방사통으로 타 병원 혹은 본원에서 수술적 치료를 권유받은 환자 중 수술 준비 과정에서 진단 및 치료 목적으로 선택적 척추 신경근 차단술을 시행한 환자를 대상으로 하였으며, 이중 5년 이상 추시가 가능하였던 69예를 대상으로 하였다. 결과분석은 진료기록부와 전화 인터뷰를 통해 하였으며. 신경차단술 시행군과 수술을 시행한 군의 치료결과 분석은 Kim's criteria (김의 평가기준), VAS(Visual analog scale) score를 이용하였다. 결과: 연구 대상 환자 69예 중 37예에서는 차단술 후에 증상 호전이 없어 수술을 시행하였고, 32예에서는 신경차단술 만으로 증상호전 되었다. 젊은 사람(60세 미만)에서 보존적 요법보다는 수술을 하는 경향이 많았으며, 이환 기간이 길수록(6개월 이상) 신경근 차단술 보다는 수술하는 경우가 높았다. 차단술 만으로도 호전된 32예의 환자 추시 결과상 다른 치료 없이 증상 호전이 지속되었던 환자는 17예(24.6%)였고 증상이 재발하여 추가 치료를 필요로 한 환자는 15예이었다. 이중 4예는 수술적 치료를 시행하였다. 결론: 수술이 예정된 하지 방사통 환자를 대상으로 수술 준비 기간 동안에 신경근 차단술을 시행하여 그 중 일부에서는 장기 추시에서도 증상 호전이 지속 되었다. 따라서 신경차단술은 수술 전에 한번 시도해 볼 만한 방법 중의 하나로 사료된다. Purpose: To evaluate the effectiveness of a selective nerve root block (SNRB) in patients with sciatica before surgery through a more than 5 year follow up. Materials and Methods: Between January 2000 and December 2000, patients with sciatica, who were recommended to undergo surgery to diagnose and treat sciatica by other clinics or at our hospital, were selected to undergo SNRB before surgery. Among them, 69 patients were followed up for 5 years. The analysis was based on the patients' medical records and telephone interviews, and the treatment results in the SNRB group and operation group were analyzed using Kim's criteria and the Visual Analog Scale score. Results: Among the 69 patients, there was no improvement in symptoms in 37 patients after SNRB. Therefore, they underwent surgery. The symptoms of the remaining 32 patients were improved by SNRB. Overall, younger patients and those with a longer symptom duration required surgery. Conclusion: SNRB was performed on patients with sciatica who were scheduled to undergo surgery. Some patients showed improvement in their symptoms in the long term. Therefore, SNRB should be considered as a treatment option prior to surgery.
Effect of Hydride Reorientation on Delayed Hydride Cracking In Zr-2.5Nb Tubes
Yun Yeo Bum,Kim Young Suk,Im Kyung Soo,Cheong Yong Moo,Kim Sung Soo Korean Nuclear Society 2003 Nuclear Engineering and Technology Vol.35 No.6
The objective of this study is to investigate the reorientation of hydrides with applied stress intensity factor, the peak temperature and the time when to apply the stress intensity factor in a Zr-2.5Nb pressure tube during its thermal cycle treatment. Cantilever beam (CB) specimens with a notch of 0.5 mm in depth made from the Zr-2.5Nb tube were subjected to electrolytic hydrogen charging to contain 60 ppm H and then to a thermal cycle involving heating to the peak temperature of either 310 or $380^{\circ}C$, holding there for 50 h and then cooling to the test temperature of $250^{\circ}C$. The stress intensity factor of either 6.13 or $18.4\;MPa\sqrt{m}$ was applied at the beginning of the thermal cycle, at the end of the hold at the peak temperatures and after cooling to the test temperature, respectively. The reorientation of hydrides in the Zr-2.5Nb tube was enhanced with the increased peak temperature and applied stress intensity factor. Furthermore, when the CB specimens were subjected to $18.4\;MPa\sqrt{m}$ from the beginning of the thermal cycle, the reoriented hydrides occurred almost all over the Zr-2.5Nb tube, surprisingly suppressing the growth of a DHC crack. In contrast, when the CB specimens were subjected to the stress intensity factor at the test temperature, little reorientation of hydrides was observed except the notch region, leading the Zr-2.5Nb to grow a large DHC crack. Based on the correlation between the reorientation of hydrides and the DHC crack growth, a governing factor for DHC is discussed along with the feasibility of the Kim's DHC model.
Physical and chemical Effects on the sonication Treatment of chitosan solution
Lee, Keun Tai,Park, Seong Min,Park, Chan Kyu,Kim, Sang Moo 한국키틴키토산학회 1997 한국키틴키토산학회지 Vol.2 No.2
물리적 방법을 이용한 키토산 올리고당의 제조에 관한 기초 자료를 제시하기 위하여 키토산용액을 20kHz의 초음파로 처리하였으며, 초음파 처리 효과에 미치는 처리 조건의 영향을 조사하였다. 키토산 용액의 고유점도는 초음파 처리 5분까지는 급속하게 감소하였고 그 이후로는 서서히 감소하였다. 키토산 용액의 부피가 작을수록 초음파 처리효과는 컸으며, 키토산 용액의 온도는 초음파 처리에 별다른 효과가 없는 것으로 나타났다. 5분간 초음파 처리 후의 점도는 용매의 종류에 따라 큰 차이가 없었으나, acetate buffer의 경우 초음파 처리효과가 가장 컸다. pH가 높을수록 초음파 처리효과는 크게 나타났으며, 이온강도와 염의 종류에 따른 효과는 나타나지 않았다. 이상의 결과에서, 용액의 부피는 10~20ml, 온도는 20~30℃, 용액의 pH는 4.5, 그리고 용매의 종류는 acetate buffer로 하는 것이 최적 초음파 처리조건으로 추정된다. As the first step of studies related to production of chitooligosaccharides by physical methods, chitosan solution were sonicated with 20kHz and various treatment effects were examined to present fundamental data of sonicated chitosan solution. Intrinsic viscosity of chitosan solution sharply decreased from 3.76dl/g to 2.90dl/g until 5 minutes of sonication and then slowly decreased. With low volume of chitosan solution, sonication was very effective and temperature of chitosan solution slightly affected the efficiency of sonication. In case of changing the solvent, no significant differences were observed on the effect of sonication, however, acetate buffer had highest sonication effect among various solvents. The sonication effect was increased as the increasement of the value of pH, on the contrary, ionic strength and type of counterions showed no effect on sonication, With these results, we assumed that optimal sonication treatment would be as follows, solution volume was 10 ~20ml, temperature range was 20~30℃ , pH value of solution was 4.5 and type of solvent was acetate buffer
Kim, Byung-Kee,Park, Yeon-Joon,Oh, Eun-Jee,Kim, Sun-Moo,Shim, Sang-In 가톨릭대학교 2000 Bulletin of The Catholic Research Institutes of Me Vol.28 No.-
Enterococcus faecium has recently emerged as a serious nosocomial pathogen. The emergence of multiple antimicrobial agent-resistant E. faecium has been remarkable; with its strains it is one of the most phenotypically heterogeneous of all enterococcal species. About 15% of enterococcal strains isolated from human clinical specimens were found to have atypical biochemical characteristics. In order to determine if these strains were E. faecium variants, intergenic riboxomal polymerase chain reation (ITS-PCR) and E. faecium PCR (EfPCR) were performed in 45 atypical strains and the two PCR results were used to analyze phenotypic characteristics of the strains. As many as 60% (27/45) of the atypical strains wrer identified as E. faecium. Thus, it is concluded that if an enterococccal strain shows positive reaction to arabinose, arginine, and ribose and negative reaction to methyl-alpha-D-glu-copyranoside and pigment, it should be identified as E. faecim. (Diagnosis Microbiology infectious Disease 34(4):269-273. 1999)
Identification of Enterococcus to the Species Level by Dot DNA Hybridization and Ribotyping
Kim, Sun Moo,Huh, Dong Ho,Park, Yeon-Joon,Kim, Byung Kee,Shim, Sang In THE CATHOLIC UNIVERSITY OF KOREA 1997 Bulletin of The Catholic Research Institutes of Me Vol.25 No.-
In this study, the abilities of Dot DNA Hybridization (DDH) and ribotyping using Bcl Ⅰ and Hind Ⅲ to distinguish enterococci to the species level were evaluated. 12 ATCC type strains(E. faecalis, E. avium, E. faecium, E. raffinosus, E. durans, E. casseliflavus, E. hirae, E. flavescens, E. malodoratus, E. gallinarum, E. mundtii, E. sulfureus) and 71 clinical isolates identified by Vitek GPI card(bio Merleux Vitek, Hazelwood, U.S.A.) were studied. For DDH, genomic DNAs of 12 ATCC type strains were labeled with biotin to be used as probes and were hybridized with 71 clinical isolates. For ribotyping, genomic DHAs of 12 ATCC strains and clinical isolates were digested with Bcl Ⅰ or Hind Ⅲ and were hybridized with 16S, 23S rDNA of E. coli. DDH Method differentiated all 12 ATCC strains except E. malodoratus and all clinical strains except E. faecium and E. hirae. Ribotyping with Bcl Ⅰ or Hind Ⅲ digestion was excellent in identification of enterococcus species, while the former was poor for E. casseliflavus and E. gallinarum, and the latter for E. durans, respectively. The results of this study suggest that ribotyping with Bcl Ⅰ or Hind Ⅲ digestion with or without DDH is excellent for reliable identification of enterococcus species.
The Preparation of Lump Activated Carbon and their Adsorption Characteristics to Heavy Metal ions
( Sang-su Jeon ),( Yong-moo Kim ) 한국공업화학회 2001 한국공업화학회 연구논문 초록집 Vol.2001 No.-
Lump Activated Carbon(LAC)was prepared with coal based granular activated carbon(GAC) and Urea resin adhesive which is made into urea and formaldehyde aqueous solution. The adsorption characteristics of GAC and LAC adsorbents were tested for the iodine and methylene blue values and investigated the effect of pH and adsorption isotherm for heavy metal ions such as Hg(II), Pb(II), Cu(II), Cr(VI). The iodine number of GAC and LAC was 1,320 and 999mg/g, methylene blue number was 150 and 122mg/g, respectively. In the adsorption characteristic of heavy metal ions on pH range tested, adsorption tendency of Hg(II), Pb(II), Cu(II) had similar properties to GAC and adsorptivity of Cr(VI) was better than that GAC. The adsorption equilibrium of Cr(VI) on GAC and LAC was fitted to the Freundlich isotherm and the other ions were fitted to the Langmuir isotherm
Molecular Effect of Calmodulin and Mlo Protein Interaction on Plant Disease Resistance
Kim, Min-Chul,Lee, Sang-Hyoung,Kim, Jong-Kyong,Chun, Hyun-Jin,Kim, Jong-Cheol,Heo, Won-Do,Chung, Woo-Sik,Choi, Man-Soo,Shon, Young-Goel,Cho, Moo-Je Gyeongsang National University Chinju, Korea 1998 Plant molecular biology and biotechnology research Vol.1998 No.