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Hui, C. Y.,Seo, K. A.,Huang, R. H. H.,Trepl, L.,Woo, Y. J.,Lu, T.-N.,Kong, A. K. H.,Walter, F. M. IOP Publishing 2012 The Astrophysical journal Vol.750 No.1
<P>ROSAT all-sky survey data have provided another window in which to search for supernova remnants (SNRs). In re-examining this data archive, a list of unidentified extended X-ray objects have been suggested as promising SNR candidates. However, most of these targets have not yet been fully explored by state-of-the-art X-ray observatories. To select a pilot target for a long-term identification campaign, we observed the brightest candidate, G308.3-1.4, with the Chandra X-ray Observatory. An incomplete shell-like X-ray structure that is well correlated with the radio shell emission at 843 MHz has been revealed. The X-ray spectrum suggests the presence of a shock-heated plasma. All these evidences confirm G308.3-1.4 as an SNR. The brightest X-ray point source detected in this field of view is also the one located closest to the geometrical center of G308.3-1.4, which has a soft spectrum. The intriguing temporal variability and the identification of the optical/infrared counterpart rule out the possibility of an isolated neutron star. On the other hand, the spectral energy distribution from the K-s band to the R band suggests a late-type star. Together with a putative periodicity of similar to 1.4 hr, the interesting excesses in the V and B bands and in H alpha suggest that this source is a promising candidate for a compact binary that survived a supernova explosion.</P>
The effect of oxygen content on the electrical characteristics of ZnO
Jung, E. S.,Kim, H. S.,Kong, B. H.,Cho, H. K.,Park, N. K.,Lee, H. S. Wiley - VCH Verlag GmbH & Co. KGaA 2007 Physica status solidi. B Vol. No.
<P>This work presents the influence of the variation of oxygen content in the ZnO films on their electrical characteristics. We applied the post-thermal annealing in N<SUB>2</SUB> and air ambient to control the oxygen content of ZnO films, which improved crystallinity and optical properties of ZnO films. The oxygen concentration was measured by Auger electron spectroscopy and the electrical characteristics were obtained by Hall measurement in the van der Pauw configuration and transmission line method. As result, it was shown that the electron concentration varies from 10<SUP>16</SUP> to 10<SUP>21</SUP>/cm<SUP>3</SUP>, while the resistivity from 10<SUP>−3</SUP> to tens ohm-cm with respect to Zn/O concentration ratio. (© 2007 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)</P>
Understanding NaI(Tl) crystal background for dark matter searches
Adhikari, G.,Adhikari, P.,Ha, C.,Jeon, E. J.,Kim, N. Y.,Kim, Y. D.,Kong, S. Y.,Lee, H. S.,Oh, S. Y.,Park, J. S.,Park, K. S. Springer-Verlag 2017 The European physical journal. C, Particles and fi Vol.77 No.7
<P>We have developed ultra-low-background NaI(Tl) crystals to reproduce the DAMA results with the ultimate goal of achieving purity levels that are comparable to or better than those of the DAMA/LIBRA crystals. Even though the achieved background level does not approach that of DAMA/LIBRA, it is crucial to have a quantitative understanding of the backgrounds. We have studied background simulations toward a deeper understanding of the backgrounds and developed background models for a 9.16-kg NaI(Tl) crystal used in the test arrangement. In this paper we describe the contributions of background sources quantitatively by performing Geant4 Monte Carlo simulations that are fitted to the measured data to quantify the unknown fractions of the background compositions. In the fitted results, the overall simulated background spectrum well describes the measured data with a 9.16-kg NaI(Tl) crystal and shows that the background sources are dominated by surface Pb-210 and internal K-40 in the 2-6-keV energy interval, which produce 2.4 counts/day/keV/kg (dru) and 0.5 dru, respectively.</P>
Kong, H.J.,Hong, G.E.,Nam, B.H.,Kim, Y.O.,Kim, W.J.,Lee, S.J.,Lee, N.S.,Do, J.W.,Cho, H.K.,Cheong, J.,Lee, C.H.,Kim, K.K. Academic Press 2009 Fish & shellfish immunology Vol.27 No.3
The cDNA encoding of a complement factor D/adipsin and kallikrein-like serine protease, designated PoDAK, was isolated from the olive flounder Paralichthys olivaceus. PoDAK cDNA encodes a polypeptide with 277 amino acids containing conserved catalytic triad residues of serine proteases. The amino acid sequence of PoDAK showed high similarity to the kallikrein-like protein of medaka, mammalian adipsin/complement factor D and tissue kallikrein homolog, KT-14 of trout, complement factor D of zebrafish, and shared 31.6-36.8% homology with complement factor D/adipsin known from other species, including mammals. Phylogenetic analysis revealed that PoDAK clustered with the kallikrein-like protein of medaka and mammalian adipsin/complement factor D and tissue kallikrein homolog KT-14 of trout. The expression of PoDAK mRNA was high in the gills and heart, moderate in muscle, liver, intestine, stomach, kidney, and spleen of healthy flounder, and increased in the kidney, liver, and spleen of flounder challenged by the viral hemorrhagic septicemia virus (VHSV) or Streptococcus iniae. In situ hybridization confirmed that PoDAK mRNA is localized in the kidney and heart of individuals infected with VHSV. Further investigations are needed to clarify the function of PoDAK in vivo and in vitro.
Kong, W.H.,Sung, D.K.,Kim, H.,Yang, J.A.,Ieronimakis, N.,Kim, K.S.,Lee, J.,Kim, D.H.,Yun, S.H.,Hahn, S.K. IPC Science and Technology Press 2016 Biomaterials Vol.81 No.-
<P>Duchenne's muscular dystrophy (DMD) is a neuromuscular disorder accompanied with muscle weakness and wasting. Since myostatin was reported to be a key regulator of muscle wasting, myostatin inhibitors have been investigated as therapeutic candidates for the treatment of muscular diseases. Here, we report an antigenic peptide of myostatin fragment (MstnF) conjugated to hyaluronate (HA) with a low molecular weight (MW, 17 kDa) for transdermal immunotherapy of DMD. Facilitating the transdermal delivery, the low MW HA showed a boosting effect on the immunization of MstnF possibly by engaging both toll-like receptors and cluster of differentiation 44 (CD44). In vivo two-photon microscopy clearly visualized the effective transdermal penetration of HA-MstnF conjugates into deep intact skin layers. The transdermal immunization of mdx mice significantly increased antibody titers against myostatin. Furthermore, the mdx mice immunized with HA-MstnF conjugates resulted in statistically significant improvement in the biochemical and pathological status of skeletal musculature as well as functional behaviors. (C) 2015 Elsevier Ltd. All rights reserved.</P>
Nam, U.W.,Rhee, J.G.,Kong, K.N.,Park, Y.S.,Jin, K.C.,Jin, H.,Park, J.H.,Yuk, I.S.,Seon, K.I.,Han, W.,Lee, D.H.,Ryu, K.S.,Min, K.W.,Edelstein, J.,Korpela, E. 한국우주과학회 2002 Journal of Astronomy and Space Sciences Vol.19 No.4
과학위성 1호의 주탑재체인 원자외선 분광기의 검출기 전자부에 대한 특성을 분석하였다. FIMS (Far-ultraviolet Imaging Spectrograph)는 교차 지연선 양극을 가진 MCP(micro-channel plate)를 사용하여 입사된 원자외선 광자의 위치를 검출한다. MCP에 입사하는 광자는 MCP을 통해 전자형태로 변환되고 증폭된다. 증폭된 전하운의 중심은 양분되어 연결된 지연선을 통해 양단으로 나가게 되고, 지연선의 양단에서 전하운의 도착시간 차이를 구하여 입사된 광자의 위치를 판독한다. FIMS의 경우 2개의 MCP 검출기를 갖고 있으며, 각각 25mm$\times$25mm의 유효 크기를 갖고있다. 또 신호처리계는 1채널의 신호처리 회로계를 통해 2개의 검출기에 대한 영상검출이 가능하도록 함으로써 신호처리계의 복잡성을 피하고 아울러 전력과 무게 비용을 줄였다. 이 시스템을 통해 높은 시간 및 공간 분해능(<$35{\times}75$ps FWHM)을 얻었으며, 6W 이하의 저전력 시스템을 구현하였다. We describe some performance of the detector electronics system for the FIMS (Far-ultraviolet Imaging Spectrograph) mission. The FIMS mission to map the far ultraviolet sky uses MCP (micro-channel plate) detectors with a crossed delay line anode to record photon arrival events. FIMS has two MCP detectors, each with a ~25mm$\times$25mm active area. The unconventional anode design allows for the use of a single set of position encoding electronics for both detector fields. The centroid position of the charge cloud, generated by the photon-stimulated MCP, is determined by measuring the arrival times at both ends of the anode following amplification and external delay. The temporal response of the detector electronics system determines the readout's positional resolution for the charge centroid. High temporal resolution (<$35{\times}75$ps FWHM) and low power consumption (< 6W) were achieved for the FIMS detector electronics system.