Prognostic factors and treatment outcomes in surgically­staged non­invasive uterine clear cell carcinoma: a Turkish Gynecologic Oncology Group study

Mustafa Erkan Sarı,Mehmet Mutlu Meydanlı,Osman Türkmen,Günsü Kimyon Cömert,Ahmet Taner Turan,Alper Karalök,Hanifi Şahin,Ali Haberal,Eda Kocaman,Özgür Akbayır,Baki Erdem,Ceyhun Numanoğlu,Kemal Güngördü 대한부인종양학회 2017 Journal of Gynecologic Oncology Vol.28 No.4

Objective: To assess the prognosis of surgically-staged non-invasive uterine clear cell carcinoma (UCCC), and to determine the role of adjuvant therapy. Methods: A multicenter, retrospective department database review was performed to identify patients with UCCC who underwent surgical treatment between 1997 and 2016 at 8 Gynecologic Oncology Centers. Demographic, clinicopathological, and survival data were collected. Results: A total of 232 women with UCCC were identified. Of these, 53 (22.8%) had surgically-staged non-invasive UCCC. Twelve patients (22.6%) were upstaged at surgical assessment, including a 5.6% rate of lymphatic dissemination (3/53). Of those, 1 had stage IIIA, 1 had stage IIIC1, 1 had stage IIIC2, and 9 had stage IVB disease. Of the 9 women with stage IVB disease, 5 had isolated omental involvement indicating omentum as the most common metastatic site. UCCC limited only to the endometrium with no extra-uterine disease was confirmed in 41 women (73.3%) after surgical staging. Of those, 13 women (32%) were observed without adjuvant treatment whereas 28 patients (68%) underwent adjuvant therapy. The 5-year disease-free survival rates for patients with and without adjuvant treatment were 100.0% vs. 74.1%, respectively (p=0.060). Conclusion: Extra-uterine disease may occur in the absence of myometrial invasion (MMI), therefore comprehensive surgical staging including omentectomy should be the standard of care for women with UCCC regardless of the depth of MMI. Larger cohorts are needed in order to clarify the necessity of adjuvant treatment for women with UCCC truly confined to the endometrium.

The Genetic Variability and Relationships of Japanese and Foreign Chickens Assessed by Microsatellite DNA Profiling

Osman, S.A.M.,Sekino, M.,Nishihata, A.,Kobayashi, Y.,Takenaka, W.,Kinoshita, K.,Kuwayama, T.,Nishibori, M.,Yamamoto, Y.,Tsudzuki, M. Asian Australasian Association of Animal Productio 2006 Animal Bioscience Vol.19 No.10

This is the first study in which genetic variability and relationships of a large number of Japanese chicken breeds were revealed along with those of several foreign breeds by using microsatellite DNA polymorphisms. Twenty-eight breeds (34 populations) of native Japanese chickens and seven foreign breeds or varieties were analyzed. The mean number of alleles per locus, the proportion of the polymorphic loci, and the expected average heterozygosity ranged from 1.75 to 4.70, from 0.55 to 1.00, and from 0.21 to 0.67, respectively. Microsatellite alleles being unique to a particular population were detected in some populations. The $D_A$ genetic distance between populations was obtained from allele frequency for every pair of the populations to construct a neighbor-joining tree. According to the phylogenetic tree, excluding a few exceptions, native Japanese chicken breeds and foreign breeds were clearly separated from each other. Furthermore, the tree topology divided native Japanese chickens into four main classes, which was almost in accordance with the classification based on body morphology; that is, (1) Cochin type, (2) Malay type, (3) layer type, and (4) intermediate type between Malay and layer types. This is the first finding for native Japanese chickens.

Properties of Soils under Different Land Uses in Chittagong Region, Bangladesh

Akhtaruzzaman, Md.,Osman, K.T.,Sirajul Haque, S.M. Institute of Forest Science 2015 Journal of Forest Science Vol.31 No.1

In this study, we investigated the effects of three land uses on soil properties in two soil layers; surface soil (0~15 cm) and subsoil (15~30 cm). Soil samples were collected from planted forest, barren lands and cultivated lands from different areas in Chittagong Cox's Bazar and analyzed for some physical and chemical properties. Results showed that soil textural class varied from sandy clay loam in planted forest and barren land site to sandy loam in cultivated soils. Maximum water holding capacity was higher in forest followed by barren land and the lowest in cultivated lands. At both soil depths, soils of cultivated land showed the highest values of bulk density (1.42 to $1.50g\;cm^{-3}$), followed by barren lands (1.37 to $1.46g\;cm^{-3}$) and the least (1.32 to $1.45g\;cm^{-3}$) in forest soils. Total porosity decreased with depth ranging from 40.24% to 41.53% in subsoils and from 42.04 to 43.23% in surface soil of cultivated and of planted forest sites respectively. The result further revealed that organic carbon (OC) and total nitrogen (TN) contents were higher in the planted forest soil than in other two land uses. The soils of all land uses under study are acidic in nature and the lowest pH was found in both surface and subsoils of barren land. Cultivated soil contained the highest amount of available P, Ca, Mg and K in both surface soil and subsoils. In contrast, barren site had the lowest contents of available P, Ca, Mg and K in both layers. The soil organic carbon (SOC) and total N storage were higher in planted forest than in barren and cultivated land uses.

Properties of Soils under Different Land Uses in Chittagong Region, Bangladesh

Md. Akhtaruzzaman,K.T. Osman,S. M. Sirajul Haque 강원대학교 산림과학연구소 2015 Journal of Forest Science Vol.31 No.1

In this study, we investigated the effects of three land uses on soil properties in two soil layers; surface soil (0∼15 cm) and subsoil (15∼30 cm). Soil samples were collected from planted forest, barren lands and cultivated lands from different areas in Chittagong Cox’s Bazar and analyzed for some physical and chemical properties. Results showed that soil textural class varied from sandy clay loam in planted forest and barren land site to sandy loam in cultivated soils. Maximum water holding capacity was higher in forest followed by barren land and the lowest in cultivated lands. At both soil depths, soils of cultivated land showed the highest values of bulk density (1.42 to 1.50 g cm-3), followed by barren lands (1.37 to 1.46 g cm-3) and the least (1.32 to 1.45 g cm-3) in forest soils. Total porosity decreased with depth ranging from 40.24% to 41.53% in subsoils and from 42.04 to 43.23% in surface soil of cultivated and of planted forest sites respectively. The result further revealed that organic carbon (OC) and total nitrogen (TN) contents were higher in the planted forest soil than in other two land uses. The soils of all land uses under study are acidic in nature and the lowest pH was found in both surface and subsoils of barren land. Cultivated soil contained the highest amount of available P, Ca, Mg and K in both surface soil and subsoils. In contrast, barren site had the lowest contents of available P, Ca, Mg and K in both layers. The soil organic carbon (SOC) and total N storage were higher in planted forest than in barren and cultivated land uses.

Soil Properties in Two Forest Sites in Cox’s Bazar, Bangladesh

Md. Akhtaruzzaman,K. T. Osman,S. M. Sirajul Haque 강원대학교 산림과학연구소 2015 Journal of Forest Science Vol.31 No.4

Soil samples were collected from three depths (0-10 cm, 10-40 cm and 40-80 cm) of two forest sites including one plantation dominated by teak with some other minor species and another degraded natural forest in Cox's Bazar, Bangladesh to compare their soil properties. Some vegetation parameters were also studied. For this study 10x10 m and 2×2 m quadrats were used for the tree and undergrowth parameters, respectively. Soil samples were also collected from these quadrats. Between the two forest types, the highest levels of organic carbon, total nitrogen, available phosphorus, exchangeable bases and cation exchange capacity (CEC) were found in soils of the plantation. The soils were acidic in nature and exchangeable Al concentrations were low. Teak dominated forest plantation had higher soil fertility index (SFI) than the degraded natural forest site. Steps for reforestation and appropriate protection are needed to improve the situation.

Extractable Micronutrients in Soils of Some Forested and Deforested Sites of South Eastern Hilly Areas of Bangladesh

Akhtaruzzaman, Md.,Osman, K.T.,Haque, S.M. Sirajul Institute of Forest Science 2018 Journal of Forest Science Vol.34 No.6

Extractable iron (Fe), manganese (Mn), zinc (Zn) and copper (Cu) contents and their distribution with depths in soils of forested and adjacent deforested areas at Jahazpura, Teknaf, Cox's Bazar of Bangladesh were studied. The soils under forest showed higher levels of DTPA-extractable micronutrients in all three layers of soil in comparison to those of the deforested areas. The differences between forested and deforested sites were, in most cases, significant.. The top soils of forested sites had the higher contents of micronutrient and generally decreased with depth in forested soils, while there was no regular trend of distribution in deforested soils. The study also revealed that contents of extractable Fe, Mn and Cu were sufficient in all depths and sites but Zn was deficient in bottom layer of forested and all three layers of deforested sites. The results suggested that organic matter, clay and soil pH could play important roles in concentrations and distributions of micronutrients in soils of the study areas.

Extractable Micronutrients in Soils of Some Forested and Deforested Sites of South Eastern Hilly Areas of Bangladesh

Md. Akhtaruzzaman,K.T. Osman,S.M. Sirajul Haque 강원대학교 산림과학연구소 2018 Journal of Forest Science Vol.34 No.6

Extractable iron (Fe), manganese (Mn), zinc (Zn) and copper (Cu) contents and their distribution with depths in soils of forested and adjacent deforested areas at Jahazpura, Teknaf, Cox’s Bazar of Bangladesh were studied. The soils under forest showed higher levels of DTPA-extractable micronutrients in all three layers of soil in comparison to those of the deforested areas. The differences between forested and deforested sites were, in most cases, significant.. The top soils of forested sites had the higher contents of micronutrient and generally decreased with depth in forested soils, while there was no regular trend of distribution in deforested soils. The study also revealed that contents of extractable Fe, Mn and Cu were sufficient in all depths and sites but Zn was deficient in bottom layer of forested and all three layers of deforested sites. The results suggested that organic matter, clay and soil pH could play important roles in concentrations and distributions of micronutrients in soils of the study areas.

Some DTPA Extractable Micronutrients in Different Hill Forest Soils of Chittagong Region, Bangladesh

Md. Akhtaruzzaman,K.T. Osman,S. M. Sirajul Haque 강원대학교 산림과학연구소 2016 Journal of Forest Science Vol.32 No.1

DTPA (Diethelene-triamine pentaacetic acid) extractable micronutrients of surface soil samples from six different locations of Cox’s Bazar and Chittagong districts were studied. All the soils under study were sufficient in DTPA extractable Fe, Mn and Cu contents. The available Zn contents in soils of Dulhazara, Chengchhari and Faissakhali under study were also above the critical limit while soils at Fulchhari, Hasnabad and CU were deficient in available Zn. The study also showed that DTPA extractable Fe content had the significant and positive relationships with clay and soil organic carbon. On the hand, negative and significant relationship was observed between extractable Mn and soil pH while DTPA extractable Zn and Cu were positively and significantly correlated with soil organic carbon of the studied area.

Soil Properties in Two Forest Sites in Cox's Bazar, Bangladesh

Akhtaruzzaman, Md.,Osman, K.T.,Sirajul Haque, S.M. Institute of Forest Science 2015 Journal of Forest Science Vol.31 No.4

Soil samples were collected from three depths (0-10 cm, 10-40 cm and 40-80 cm) of two forest sites including one plantation dominated by teak with some other minor species and another degraded natural forest in Cox's Bazar, Bangladesh to compare their soil properties. Some vegetation parameters were also studied. For this study $10{\times}10\;m$ and $2{\times}2\;m$ quadrats were used for the tree and undergrowth parameters, respectively. Soil samples were also collected from these quadrats. Between the two forest types, the highest levels of organic carbon, total nitrogen, available phosphorus, exchangeable bases and cation exchange capacity (CEC) were found in soils of the plantation. The soils were acidic in nature and exchangeable Al concentrations were low. Teak dominated forest plantation had higher soil fertility index (SFI) than the degraded natural forest site. Steps for reforestation and appropriate protection are needed to improve the situation.

Some DTPA Extractable Micronutrients in Different Hill Forest Soils of Chittagong Region, Bangladesh

Akhtaruzzaman, Md.,Osman, K.T.,Sirajul Haque, S.M. Institute of Forest Science 2016 Journal of Forest Science Vol.32 No.1

DTPA (Diethelene-triamine pentaacetic acid) extractable micronutrients of surface soil samples from six different locations of Cox's Bazar and Chittagong districts were studied. All the soils under study were sufficient in DTPA extractable Fe, Mn and Cu contents. The available Zn contents in soils of Dulhazara, Chengchhari and Faissakhali under study were also above the critical limit while soils at Fulchhari, Hasnabad and CU were deficient in available Zn. The study also showed that DTPA extractable Fe content had the significant and positive relationships with clay and soil organic carbon. On the hand, negative and significant relationship was observed between extractable Mn and soil pH while DTPA extractable Zn and Cu were positively and significantly correlated with soil organic carbon of the studied area.