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Usefulness of for BI-RAD category 4 or higher lesions
Jun Suk Byun,Hyeon Hwa Oh,Hye Yoon Lee,Keum Won Kim,Jin Suk Kim,Dae Sung Yoon 대한종양외과학회 2017 Korean Journal of Clinical Oncology Vol.13 No.1
Purpose: As an alternative to core-needle biopsy in confirming the diagnosis of breast cancer, the usefulness of 99mTc-sestamibi scintimammography (MIBI scan) has been rarely reported. Thus, we aimed to evaluate a direct comparison between general diagnostic modalities and breast MIBI scan, which may be revealed as a potential diagnostic alternative. Methods: In a retrospective study, 301 patients with 801 lesions, who underwent breast MIBI scan, ultrasonography, and mammography simultaneously between January 2013 and February 2015, were reviewed. All data were analyzed by McNemar and Kappa test for statistical significance. Results: Mean age was 49.2±9.37 years old (range from 26 to 85 years old). Results of Breast MIBI scan were divided into three categories: 236 positive intensity uptakes (29.5%), 565 negative intensity uptakes (70.5%), and 67 suspicious abnormal intensity uptakes (8.4%). Pathologic reports were also allocated into four subgroups: 122 invasive cancers (15.2%), 44 non-invasive cancers (5.5%), 194 proliferative benign lesions (24.2%), and 441 non-proliferative benign lesions (55.1%). The sensitivity, specificity, positive predictive value, and negative predictive value of MIBI scan were 83.5%, 55.6%, 59.1%, and 95.2%, respectively. Specificity of MIBI scan plus general diagnostic modalities increased dramatically, up to 85.2%, compared to general modalities (6.8%). Conclusion: In general diagnostic modalities, such as mammography and ultrasound, BI-RAD category 4 or higher lesions were performed by needle biopsy rather than observation. The outstanding specificity and negative predictive value of MIBI scan provided confident results on non-proliferative benign lesions. MIBI scan may offer an alternative diagnostic tool for “invasive” biopsy procedures.
Jun Suk Byun,Hye Yoon Lee,Ki Won Chun,윤대성 대한갑상선학회 2016 International Journal of Thyroidology Vol.9 No.2
Papillary thyroid carcinoma (PTC) is a common lesion, accounting for 70-80% of all thyroid cancers, whereas mucosa-associated lymphoid tissue (MALT) lymphoma of thyroid gland is rare. A simultaneous occurrence of both malignancies is extremely rare. 57 years old Korean woman diagnosed with Hashimoto’s thyroiditis at left lobe of thyroid gland where atypical cells of undetermined significance at right lobe. Later, left lobe was confirmed with malignant lymphoma during series of fine-needle aspiration biopsy. Right lobe was interpreted as malignant lesions, such as papillary thyroid carcinoma based on ultrasonography images and previous biopsy results. Total thyroidectomy was performed. Pathology reported papillary thyroid carcinoma at right lobe and MALT lymphoma at left lobe. There were no post-operative complications and no recurrence yet reported. Since an association between Hashimoto’s thyroiditis and development of MALT lymphoma has been reported previously, a history of Hashimoto thyroiditis should be suspected MALT lymphoma.
Obesity induced by high fat diet in Rhomboid family member 2 (Rhbdf2) KO mice
Sung-Jun Kim(Sung-Jun Kim),Seul Gi Park(Seul Gi Park),Young-Sub Byun(Young-Sub Byun),Eun-Kyoung Kim(Eun-Kyoung Kim),Sang-Mi Cho(Sang-Mi Cho),Harim Kim(Harim Kim),Young-Suk Won(Young-Suk Won),Hyoung-Ch 한국예방수의학회 2017 한국예방수의학회 학술대회자료집 Vol.2017 No.-
Improving the predictability of stock market returns with the growth of options open interest
Suk Joon Byun,Jun Sik Kim 한국재무학회 2013 한국재무학회 학술대회 Vol.2013 No.05
The purpose of this paper is to show that the growth of options open interest has predictive power for stock market returns. Predictability is demonstrated through in-sample tests, as evidenced by significant p-values and the improvement of adjusted R2 in monthly predictive regressions, and out-of-sample metrics. In addition, the stock return predictability confirms the economic significance, as shown by improving Sharpe ratios of returns from a predictor variablebased decision rule that exploit the growth of options open interest. Our empirical evidence indicates that the growth of options open interest contains additional information for future stock market returns, relative to other popular predictor variables.
Byun, Jong Min,Bang, Su-Ryong,Kim, Hyun Woo,Kim, Tae-Yeob,Hong, Suk-Jun,Kim, Young Do Elsevier 2017 Surface & coatings technology Vol.309 No.-
<P><B>Abstract</B></P> <P>In this study, as the alternatives to the depletion of Zn resources, the Zn-Mg alloy was deposited on a steel substrate by a PVD process. Considering the difference of vapor pressure between Zn and Mg in vacuum condition, Zn, Mg and Zn were sequentially coated by PVD process to form a uniform coating layer, and a heat treatment was separately conducted at 200°C under vacuum condition. As the heating time increased, the volume fraction of the intermetallic compound phases (Mg<SUB>2</SUB>Zn<SUB>11</SUB> and MgZn<SUB>2</SUB>) gradually increased up to the heat-treated sample for 360s. From the 0T-bending test, delamination of the coating layer was observed from heat-treated sample for 240s which is composed of over 85% of the intermetallic compound phases. And from the salt spray test, it is confirmed that the red rust generation time was 624h in heat-treated sample for 360s which was composed entirely of Zn-Mg intermetallic compound phases.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The Zn, Mg and Zn were sequentially coated on steel sheet by PVD method. </LI> <LI> The effect of heat treatment on the phase transition, corrosion resistance, and adhesion property was investigated. </LI> <LI> As heat treatment time increased for 360s, the coating layer was entirely composed of intermetallics (Mg<SUB>2</SUB>Zn<SUB>11</SUB> and MgZn<SUB>2</SUB>). </LI> <LI> The red rust generation time was 624h in heat-treated sample for 360s. </LI> <LI> The delamination of coating layer was observed from heat-treated sample for 240s which were composed of 85% intermetallics. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
The Information content of the risk-neutral skewness for Volatility Forecasting
Suk Joon Byun,Jun Sik Kim 한국재무학회 2011 한국재무학회 학술대회 Vol.2011 No.05
This paper investigates the information content of the risk-neutral skewness derived from S&P 500 index option prices for forecasting future volatility. Empirical results show that the risk-neutral skewness provides incremental explanatory power for future volatility. Moreover, the models with the risk-neutral skewness dominate in terms of out-of-sample forecasting performance, especially during the 2007-2008 financial crisis.
Estimation of Stochastic Volatility with High and Low Prices
Suk Joon Byun,Jung-Soon Hyun,Woon Jun Sung 한국재무학회 2014 한국재무학회 학술대회 Vol.2014 No.11
This paper suggests stochastic volatility models incorporating both the leverage effect and information on the daily high/low prices of stocks. The leverage effect is measured using open-to-close returns and two distinct intraday data, ranges, defined by the differences between daily high and low log-prices, and extreme prices in order to detect asymmetric volatility behavior. The likelihood-based inferences of Markov Chain Monte Carlo (MCMC) are conducted to estimate parameters and volatility. The simulation study reveals that the proposed model is superior to a traditional stochastic volatility model using returns only but there is little difference between estimators using ranges or high/low prices. Performing an empirical analysis using the E-mini S&P 500 and the Nasdaq 100 Futures, we find strong evidence of the leverage effect even when information of high/low prices is incorporated.
Co-methanation of CO and CO2 on the NiX-Fe1− X/Al2O3 catalysts; effect of Fe contents
Suk-Hwan Kang,Yong-Done Yoo,Jae-Hong Ryu,Jin-Ho Kim,Seok-Jung Seo,Potharaju S. Sai Prasad,Hyo-Jun Lim,Chang-Dae Byun 한국화학공학회 2011 Korean Journal of Chemical Engineering Vol.28 No.12
The co-methanation of carbon dioxide containing syngas was carried out on Al2O3 supported NixFe1−x (x is 0.1, 0.3, 0.5, 0.7 and 0.9) catalysts for synthetic natural gas (SNG) production. The catalysts were prepared by wetimpregnation method taking 20 weight percent of the metallic component over the support, and its characteristics were analyzed by BET surface area, XRD and H2-TPR. The maximum carbon conversion and CH4 selectivity are achieved on Ni0.7Fe0.3/Al2O3 catalyst. Further, increase of Fe content led to enhancing the water gas shift reaction and hydrocarbon formation.