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Application of SA-SVM Incremental Algorithm in GIS PD Pattern Recognition
Tang, Ju,Zhuo, Ran,Wang, DiBo,Wu, JianRong,Zhang, XiaoXing The Korean Institute of Electrical Engineers 2016 Journal of Electrical Engineering & Technology Vol.11 No.1
With changes in insulated defects, the environment, and so on, new partial discharge (PD) data are highly different from the original samples. It leads to a decrease in on-line recognition rate. The UHF signal and pulse current signal of four kinds of typical artificial defect models in gas insulated switchgear (GIS) are obtained simultaneously by experiment. The relationship map of ultra-high frequency (UHF) cumulative energy and its corresponding apparent discharge of four kinds of typical artificial defect models are plotted. UHF cumulative energy and its corresponding apparent discharge are used as inputs. The support vector machine (SVM) incremental method is constructed. Examples show that the PD SVM incremental method based on simulated annealing (SA) effectively speeds up the data update rate and improves the adaptability of the classifier compared with the original method, in that the total sample is constituted by the old and new data. The PD SVM incremental method is a better pattern recognition technology for PD on-line monitoring.
Application of SA-SVM Incremental Algorithm in GIS PD Pattern Recognition
Ju Tang,Ran Zhuo,DiBo Wang,JianRong Wu,XiaoXing Zhang 대한전기학회 2016 Journal of Electrical Engineering & Technology Vol.11 No.1
With changes in insulated defects, the environment, and so on, new partial discharge (PD) data are highly different from the original samples. It leads to a decrease in on-line recognition rate. The UHF signal and pulse current signal of four kinds of typical artificial defect models in gas insulated switchgear (GIS) are obtained simultaneously by experiment. The relationship map of ultrahigh frequency (UHF) cumulative energy and its corresponding apparent discharge of four kinds of typical artificial defect models are plotted. UHF cumulative energy and its corresponding apparent discharge are used as inputs. The support vector machine (SVM) incremental method is constructed. Examples show that the PD SVM incremental method based on simulated annealing (SA) effectively speeds up the data update rate and improves the adaptability of the classifier compared with the original method, in that the total sample is constituted by the old and new data. The PD SVM incremental method is a better pattern recognition technology for PD on-line monitoring.
Superovulation and Transplantation of Demi- and Aggregated Embryos in Rabbits
Ju, J.C.,Chang, Y.C.,Huang, W.T.,Tang, P.C.,Cheng, S.P. Asian Australasian Association of Animal Productio 2001 Animal Bioscience Vol.14 No.4
The effect of exogenous gonadotrophins on superovulation in rabbits was examined. One hundred and sixteen sexually mature California, Chinchilla and New Zealand White rabbits were randomly allocated to control (100 IU hCG), PMSG-treated (100 IU HCG following 150 IU PMSG) and FSH-treated groups (0.3 mg/head /12 h for 3 days followed by 100 IU hCG). All does were mated after hCG injection and were sacrificed or laparotomized within 1 to 4 days postcoitus for counting the number of ovulation points. The number of ovulations was higher in FSH-treated animals than in the control and PMSG-treated groups (37.2 vs. 10.4 and 14.5, p<0.05). Follicle haemorrhagicum was observed in many cases in the PMSG-treated group. No significant difference in ovulation number was observed between left and right ovaries regardless of gonadotropin treatment. In another experiment, 2-cell stage embryos were collected at 26 h postmating and blastomeres were separated by mechanical pipetting or gentle pressure with a fine glass needle. Aggregated or chimeric embryos were produced from two single blastomeres from two breeds, New Zealand White and Chinchlla, with different coat colors. All the embryos were cultured in Ham's F-10 medium supplemented with 1.5% BSA (bovine serum albumin fraction V) and 10% PRS (pregnant rabbit serum), and incubated in a humidified atmosphere with 5% $CO_2$ at $38^{\circ}C$. After development to morula or early blastocyst, the embryos were transferred into the oviducts of recipient does. Results showed that 7 out of 10 does (70%) receiving intact embryos (control) became pregnant and 41 kits were delivered. However, no pregnancy was obtained from the recipient of either denuded demi- or aggregated embryos. It is suggested that embryos without zona pellucida could not develop to term in rabbits.
Tang, YuJiao,Jeon, Byong-Tae,Wang, Yanmei,Choi, Eun-Ju,Kim, Yon-Suk,Hwang, Jin-Woo,Park, Pyo-Jam,Moon, Sang Ho,Kim, Eun-Kyung Korean Society for Food Science of Animal Resource 2015 한국축산식품학회지 Vol.35 No.4
Deer velvet antler (DVA) is one of the most popular medicines in China. Numerous studies have demonstrated that velvet antler possess biological effects. However, data regarding its anti-migration activity on prostate cancer is scarce. In this study, we investigated the inhibitory effect of top DVA (T-DVA) on the expression of prostate-specific antigen (PSA) and migration-related genes in the human prostate cancer cell, LNCaP. The T-DVA down-regulated the expression of PSA. In addition, the Radius<sup>TM</sup> assay revealed that T-DVA inhibited the migration behavior of prostate cancer cells. Furthermore, the expression of matrix metalloproteinase (MMP)-9 and vascular endothelial growth factor (VEGF) was also decreased with T-DVA. On the contrary, T-DVA increased the tissue inhibition of metallo-proteinase (TIMP)-1 and (TIMP)-2. Taken together, our findings indicate that the T-DVA possesses anti-migration activity on prostate cancer cells. This is the first study of DVA to report the anti-migration activity on prostate cancer.
Tang, Yujiao,Jeon, Byong-Tae,Wang, Yanmei,Choi, Eun-Ju,Park, Pyo-Jam,Seong, Hye-Jin,Moon, Sang Ho,Kim, Eun-Kyung Hindawi Limited 2015 Journal of chemistry Vol.2015 No.-
<P>We investigated the biologically active substances contained in RVA (regrowth velvet antler) by comparing the composition of biologically active substances and antioxidant potential of different antler segments. RVA was subjected to extraction using DW (distilled water). RVA was divided into 3 segments: T-RVA (top RVA), M-RVA (middle RVA), and B-RVA (base RVA). The T-RVA section possessed the greatest amounts of uronic acid (36.251 mg/g), sulfated GAGs (sulfated glycosaminoglycans) (555.76 mg/g), sialic acid (111.276 mg/g), uridine (0.957 mg/g), uracil (1.084 mg/g), and hypoxanthine (1.2631 mg/g). In addition, the T-RVA section possessed the strongest antioxidant capacity as determined by DPPH, H2O2(hydrogen peroxide), hydroxyl, and ABTS (2,2′-azinobis-3-ethylbenzthiazoline-6-sulphonate) radical scavenging activity as well as FRAP (ferric reducing antioxidant power) and ORAC (oxygen radical absorbance capacity). The values of those were 53.44, 23.09, 34.12, 60.31, and 35.81 TE/<I>μ</I>M at 1 mg/mL and 113.57 TE/<I>μ</I>M at 20 <I>μ</I>g/mL. These results indicate that the T-RVA section possesses the greatest amount of biologically active substances and highest antioxidant potential. This is the first report on the biologically active substances and antioxidant potential of RVA.</P>
Tang, Xue-Lian,Yang, Xin-Ying,Jung, Hyun-Ju,Kim, Sung-Yeon,Jung, Suk-Yul,Choi, Du-Young,Park, Won-Cheol,Park, Hyun Pharmaceutical Society of Japan 2009 Biological & pharmaceutical bulletin Vol.32 No.8
<P>Cancer is one of the leading causes of death in the world. The triterpenoid compound asiatic acid derived from the tropical medicinal plant <I>Centella asiatica</I> displays cytotoxic activity on fibroblast cells and several other kinds of cells. The present work studies asiatic acid-mediated growth inhibition of cancer cells and the underlying mechanism. Asiatic acid markedly inhibited cancer cell proliferation. Apoptosis of SW480 human colon cancer cells was induced by asiatic acid as shown by flow cytometry, DNA fragmentation and nuclear chromatin condensation experiments. Through increasing mitochondrial membrane permeability and cytochrome <I>c</I> release from mitochondria into cytosol, asiatic acid induced caspase-9 activity, which further activated caspase-3 and poly(ADP-ribose) polymerase cleavage resulting in irreversible apoptotic death in the tumor cells. Taken together, these results suggest that mitochondrial death apoptosis cascade plays very important roles in asiatic acid-induced cancer apoptosis.</P>
Tang, Yujiao,Fan, Meiqi,Choi, Young-Jin,Choi, Eun-Ju,Moon, Sang-Ho,Debnath, Trishna,Yu, Yonghai,Lee, Il Nam,Kim, Eun-Kyung Hindawi Limited 2018 Journal of chemistry Vol.2018 No.-
<P>We previously discovered the antioxidant and antiprostate cancer effects of antler extract (AE), but whether it inhibits cisplatin- (Cis-) induced toxicity has not been investigated. In this study, the effect of AE on Cis-induced side effects in the kidney and liver using 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide-based cytotoxicity and cell cycle assays in prostate cancer PC-3 cells in vitro is investigated. Furthermore, we used a xenograft mouse model of the same cells to examine the in vivo effects and mechanisms of action. Cis and Cis + AE treatment attenuated prostate cancer cell growth by inducing apoptosis in vitro. Cis + AE stimulated cleaved caspases 3, 7, and 9 and polyadenosine diphosphate ribose polymerase expression. Cis + AE treatment for 1 week significantly increased the superoxide dismutase and catalase antioxidant activity while thiobarbituric acid reactive substances decreased. The histopathological damage and tumor necrosis factor-α, interleukin- (IL-) 1<I>β</I> and IL-6, cyclooxygenase-2, and inducible nitric oxide synthase expression in the kidney and liver tissue decreased. Therefore, AE likely possesses antiprostate cancer activity and inhibits Cis toxicity.</P>