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Bright Owusu Asante,Jonas Osei-Adu,Kwasi Offei Bonsu,Michael Kwabena Osei,Richard Adabah,Stephen John Ayeh,John Okyere,Cho Gyoungrae,Jeon Hakyung,Hong Soonsung 한국국제농업개발학회 2020 韓國國際農業開發學會誌 Vol.32 No.2
This paper examined farmers’ perceptions and preferences for improved varietal traits in the Wenchi and Offinso North Municipalities of Ghana. Data from 306 randomly selected tomato farmers were analyzed using perception indices, Kendall’s Coefficient of concordance and the Poisson regression model. The results show that tomato farmers are willing to adopt an improved variety with long shelf life, good fruit quality and large fruit size. The study further indicates that tomato farmers lack requisite skills in pest and disease management. The number of varietal attributes preferred by farmers was positively influenced by sex of farmer, education, experience in tomato cultivation, household size, access to credit, FBO membership, extension contacts farm size and off-farm income. These factors and attributes need to be carefully considered by breeders and policy makers in the development of an improved tomato variety to enhance its uptake. The major constraints identified in tomato production include limited access to capital followed by low commodity prices coupled with low demand with the least constraint being access to tractors for land preparation. The potential of adoption of improved tomato varieties in Ghana will be augmented through paragenetic measures towards addressing these constraints.
Dietary Lutein Modulates Growth and Survival Genes in Prostate Cancer Cells
Mohamed M. Rafi,Saravanan Kanakasabai,Sarita V. Gokarn,Eric G. Krueger,John J. Bright 한국식품영양과학회 2015 Journal of medicinal food Vol.18 No.2
Lutein is a carotenoid pigment present in fruits and vegetables that has anti-inflammatory and antitumor properties. In this study, we examined the effect of lutein on proliferation and survival-associated genes in prostate cancer (PC-3) cells. We found that in vitro culture of PC-3 cells with lutein induced mild decrease in proliferation that improved in combination treatment with peroxisome proliferator-activated receptor gamma (PPARγ) agonists and other chemotherapeutic agents. Flow cytometry analyses showed that lutein improved drug-induced cell cycle arrest and apoptosis in prostate cancer. Gene array and quantitative reverse transcription-polymerase chain reaction analyses showed that lutein altered the expression of growth and apoptosis-associated biomarker genes in PC-3 cells. These findings highlight that lutein modulates the expression of growth and survival-associated genes in prostate cancer cells.
Significance of Facet Fluid Index in Anterior Cervical Degenerative Spondylolisthesis
Lee Yunsoo,Heard Jeremy C.,Lambrechts Mark J.,Kern Nathaniel,Wiafe Bright,Goodman Perry,Mangan John J.,Canseco Jose A.,Kurd Mark F.,Kaye Ian D.,Hilibrand Alan S.,Vaccaro Alexander R.,Kepler Christophe 대한척추외과학회 2024 Asian Spine Journal Vol.18 No.1
Study Design: Retrospective cohort study.Purpose: To correlate cervical facet fluid characteristics to radiographic spondylolisthesis, determine if facet fluid is associated with instability in cervical degenerative spondylolisthesis, and examine whether vertebral levels with certain facet fluid characteristics and spondylolisthesis are more likely to be operated on.Overview of Literature: The relationship between facet fluid and lumbar spondylolisthesis is well-documented; however, there is a paucity of literature investigating facet fluid in degenerative cervical spondylolisthesis.Methods: Patients diagnosed with cervical degenerative spondylolisthesis were identified from a hospital’s medical records. Demographic and surgical characteristics were collected through a structured query language search and manual chart review. Radiographic measurements were made on preoperative MRIs for all vertebral levels diagnosed with spondylolisthesis and adjacent undiagnosed levels between C3 and C6. The facet fluid index was calculated by dividing the facet fluid measurement by the width of the facet. Bivariate analysis was conducted to compare facet characteristics based on radiographic spondylolisthesis and spondylolisthesis stability.Results: We included 154 patients, for whom 149 levels were classified as having spondylolisthesis and 206 levels did not. The average facet fluid index was significantly higher in patients with spondylolisthesis (0.26±0.07 vs. 0.23±0.08, p <0.001). In addition, both fluid width and facet width were significantly larger in patients with spondylolisthesis (p <0.001 each). Cervical levels in the fusion construct demonstrated a greater facet fluid index and were more likely to have unstable spondylolisthesis than stable spondylolisthesis (p <0.001 each).Conclusions: Facet fluid index is associated with cervical spondylolisthesis and an increased facet size and fluid width are associated with unstable spondylolisthesis. While cervical spondylolisthesis continues to be an inconclusive finding, vertebral levels with spondylolisthesis, especially the unstable ones, were more likely to be included in the fusion procedure than those without spondylolisthesis.