RISS 학술연구정보서비스

검색
다국어 입력

http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.

변환된 중국어를 복사하여 사용하시면 됩니다.

예시)
  • 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
  • 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
닫기
    인기검색어 순위 펼치기

    RISS 인기검색어

      검색결과 좁혀 보기

      선택해제
      • 좁혀본 항목 보기순서

        • 원문유무
        • 원문제공처
          펼치기
        • 등재정보
          펼치기
        • 학술지명
          펼치기
        • 주제분류
          펼치기
        • 발행연도
          펼치기
        • 작성언어
        • 저자
          펼치기

      오늘 본 자료

      • 오늘 본 자료가 없습니다.
      더보기
      • 무료
      • 기관 내 무료
      • 유료
      • SCISCIESCOPUS

        Efficient CQI feedback via network coding for wireless relay networks

        Jinyoung Oh,Jin-Yup Hwang,Jeongchan Kim,Youngnam Han IEEE 2009 IEEE communications letters Vol.13 No.10

        <P>For the efficacy of radio resource management in downlink wireless relay networks, the channel quality indicator (CQI) between a mobile station (MS) and a relay station (RS) should be fed back from the RS to its base station (BS), at the cost of additional feedback overhead. In this letter, we propose an efficient feedback scheme based on network coding between a pilot sequence and the CQI of MS-RS link, through which the BS can have both CQIs of MS-RS and RS-BS links without overhead. Numerical results reveal that the proposed CQI reporting scheme has as good feedback performance as conventional one which generally requires additional feedback burden.</P>

      • KCI등재후보

        Cerebral Venous Thrombosis Combined with Spontaneous Intracranial Hypotension: A Case Report and Review of the Literature

        Jinyoung Oh,Sang Won Han,Sun Yoon Chung 대한신경초음파학회 2023 대한신경초음파학회지 (JNN) Vol.15 No.1

        Several cases of cerebral venous thrombosis (CVT) due to spontaneous intracranial hypotension (SIH) have been reported, with an estimated occurrence rate of 1–2% among patients with decreased intracranial pressure. However, the causal relationship between SIH and CVT as a potential risk factor is not well understood. According to the Monro-Kellie principle, this is thought to be caused by compensatory expansion of the cerebral venous system, damage to the intravenous wall due to changes in cerebral buoyancy, or increased venous blood viscosity. Although anticoagulation therapy is typically the first choice of treatment for patients diagnosed with CVT, considering the potential risk of intracerebral hemorrhage in patients with CVT secondary to SIH is important. We report the case of a patient who developed CVT as a complication of SIH and discuss its mechanisms and treatment options. Early identification and appropriate treatment can lead to successful outcomes and the prevention of potential complications.

      • TCF7L2 Modulates Glucose Homeostasis by Regulating CREB- and FoxO1-Dependent Transcriptional Pathway in the Liver

        Oh, Kyoung-Jin,Park, Jinyoung,Kim, Su Sung,Oh, Hyunhee,Choi, Cheol Soo,Koo, Seung-Hoi,Puigserver, Pere Public Library of Science 2012 PLoS genetics Vol.8 No.9

        <▼1><P>Peripheral insulin resistance contributes to the development of type 2 diabetes. TCF7L2 has been tightly associated with this disease, although the exact mechanism was largely elusive. Here we propose a novel role of TCF7L2 in hepatic glucose metabolism in mammals. Expression of medium and short isoforms of TCF7L2 was greatly diminished in livers of diet-induced and genetic mouse models of insulin resistance, prompting us to delineate the functional role of these isoforms in hepatic glucose metabolism. Knockdown of hepatic TCF7L2 promoted increased blood glucose levels and glucose intolerance with increased gluconeogenic gene expression in wild-type mice, in accordance with the PCR array data showing that only the gluconeogenic pathway is specifically up-regulated upon depletion of hepatic TCF7L2. Conversely, overexpression of a nuclear isoform of TCF7L2 in high-fat diet-fed mice ameliorated hyperglycemia with improved glucose tolerance, suggesting a role of this factor in hepatic glucose metabolism. Indeed, we observed a binding of TCF7L2 to promoters of gluconeogenic genes; and expression of TCF7L2 inhibited adjacent promoter occupancies of CREB, CRTC2, and FoxO1, critical transcriptional modules in hepatic gluconeogenesis, to disrupt target gene transcription. Finally, haploinsufficiency of TCF7L2 in mice displayed higher glucose levels and impaired glucose tolerance, which were rescued by hepatic expression of a nuclear isoform of TCF7L2 at the physiological level. Collectively, these data suggest a crucial role of TCF7L2 in hepatic glucose metabolism; reduced hepatic expression of nuclear isoforms of this factor might be a critical instigator of hyperglycemia in type 2 diabetes.</P></▼1><▼2><P><B>Author Summary</B></P><P>Previous genome-wide association studies revealed that TCF7L2 is a strong candidate for a type 2 diabetes gene. However, the direct involvement of TCF7L2 on hepatic glucose metabolism has been elusive to date. Here we show that TCF7L2 is critical in mediating transcriptional control of hepatic glucose production. We found that hepatic expression of nuclear isoforms of TCF7L2 was reduced in mouse models of insulin resistance. Acute depletion of TCF7L2 in the liver promoted glucose intolerance and up-regulation of gluconeogenic genes, while ectopic expression of TCF7L2 in DIO mice improved glucose tolerance. TCF7L2 was shown to bind to the gluconeogenic promoters, thereby interfering with the promoter occupancies of both CREB/CRTC2 and FoxO1 on their cognate sites. Furthermore, TCF7L2 haploinsufficiency promoted higher glucose levels with impaired glucose tolerance and increased hepatic glucose production in mice, and adenovirus-mediated TCF7L2 expression in the liver reversed the phenotype. We propose that TCF7L2 is a critical player in regulating glucose homeostasis in mammals by modulating hepatic glucose production.</P></▼2>

      • SCOPUSKCI등재SCIE

        Trends in the prescription of opioids and gabapentinoids in patients with failed back surgery syndrome in Korea: a population-based study

        ( Jinyoung Oh ),( Jinseok Yeo ) 대한통증학회 2024 The Korean Journal of Pain Vol.37 No.1

        Background: Failed back surgery syndrome (FBSS) is a chronic condition that is characterized by persistent back pain following one or more spinal surgeries. Pharmacological interventions, such as the use of opioids and gabapentinoids, are frequently used in the treatment of FBSS. However, prolonged and excessive use of these medications can lead to dependence and adverse effects. This study investigates trends in opioid and gabapentinoid prescriptions among patients with FBSS in Korea from 2016 to 2020. Methods: Data from the Health Insurance and Review Agency were analyzed, and claims listing FBSS were selected for the study. Prescription patterns of opioids and gabapentinoids were classified based on the number of days prescribed per year. Results: Of the 390,095 patients diagnosed with FBSS, 41.6% of the patients were prescribed gabapentinoids, and 42.0% of them were prescribed opioids, while 10.6% of the patients were classified as long-term gabapentinoid users, 11.4% as long-term opioid users, and 7.4% of the patients were found to have long-term prescriptions for both drugs. The proportion of patients who received both gabapentinoid and opioid prescriptions increased annually. The doses of opioids prescribed have also increased along with the increase in the number of patients receiving opioid prescriptions. Conclusions: The prescription rates of opioids and gabapentinoids among patients with FBSS in Korea continue to increase steadily, posing potential risks of addiction and adverse effects. Further research is needed to better understand the actual status of addiction in patients with FBSS.

      • A colorimetric chemosensor for heptanal with selectivity over formaldehyde and acetaldehyde through synergistic interaction of hydrophobic interactions and oxime formation

        Oh, Jinyoung,Kang, Seungyoon,Lee, Cheol Gyu,Han, Min Su The Royal Society of Chemistry 2018 The Analyst Vol.143 No.19

        <P>Aldehydes with long alkyl chains are important biomarkers, but chemosensors for the detection of the aldehydes have been rarely reported. Herein, a chemosensor based on hydroxylamine-functionalized polydiacetylene (PDA) was developed for the selective detection of heptanal, which contains a long alkyl chain. The hydroxylamine group of PDA reacts with the aldehyde group of heptanal, while hydrophobic interactions between the alkyl chains of PDA and heptanal occur simultaneously. As a result, synergistic interactions with the aldehyde group and alkyl chain on heptanal allowed for the selective detection of heptanal over formaldehyde and acetaldehyde, which do not contain long alkyl chains. The consequent perturbation of the backbone by the synergistic interactions induced a blue-to-purple color transition, allowing for colorimetric detection by the naked eye. The chemosensor had an estimated detection limit of 4.8 μM. In addition, the sensor system was applied to determine heptanal concentrations in serum samples.</P>

      • KCI우수등재
      • KCI등재

        한국 보훈보상 제도 및 정책의 변화와 신제도주의 이론: 정치 민주화 시기의 분석, 1987-2002

        오진영(Jinyoung Oh),김윤태(Yuntae Kim) 비판과 대안을 위한 사회복지학회 2021 비판사회정책 Vol.- No.72

        이 논문은 1987년 민주화 이후 노태우 정부, 김영삼 정부, 김대중 정부에서 일어난 보훈보상 제도와 정책의 주요 변화를 분석한다. 특히 보훈보상 제도 가운데 보훈 대상과 보훈 급여금이 확대되는 원인과 과정을 신제도주의 관점에서 분석하면서 민주화 이전 시기의 보훈보상 제도 및 정책과 다른 특징을 설명한다. 연구 방법은 1987년에서 2002년까지 3개 정부의 존속 기간 동안 보훈 대상과 보훈 급여금에 관한 제도 변화 사례 전체(58건)를 대상으로 주로 문헌조사를 활용한 제도 분석을 실시하였다. 보훈보상 관련변화 사례를 형성, 대체, 층화, 표류, 전환의 다섯 가지 유형으로 분류하고 주요 특징을 추출하였다. 이 연구는 정치 민주화 시기에 보훈보상 제도의 정치화가 심화되어 보훈 대상과 범위가 과도하게 확대되었으며 역설적으로 복지의 이원화 내지 불균형을 초래했다는 결론에 이르렀다. 앞으로의 보훈보상 제도의 기능과 역할은 사회정책 개혁에 기반한 복지국가의 발전과 연계하여 새로운 변화가 필요하다. The purpose of this paper is to evaluate the characteristics of main changes with regard to the Korea’s Reward System for Persons of Distinguished Service to the State (KRSPDSS) from Roh Tae-woo administration to Kim Dae-jung’s, since political democratization in 1987. We attempt to analyse the causes and processes of the law enactment. This article pursues to explain the changes in coverage and benefit level of the veterans system of democratic governments, compared to authoritarian governments. Based on a new institutionalism perspective, we analyze major 58 law enactments to explain institutional changes of the veterans system from 1987 until 2002. The results show that there are five types of institutional changes: formation, displacement, layering, drift, and conversion. We found that the politicization of the veterans system along with the immaturity of the welfare state resulted in the excessive expansion of the veterans system in terms of coverage and benefit level. KRSPDSS needs to be reorganized as the welfare state has developed more universal social policy system.

      연관 검색어 추천

      이 검색어로 많이 본 자료

      활용도 높은 자료

      해외이동버튼