Impact of an Information Leaflet on Knowledge of Hepatocellular Carcinoma and Hepatitis B among Chinese Youth

Ouyang, Jun-Jie,He, Wen-Jing,Zheng, Kai-Xin,Chen, Geng-Zhen Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.1

Background: To assess the effect of an information leaflet on the level of Chinese youth's knowledge about hepatitis B and hepatocellular carcinoma (HCC), the most common type of primary liver cancer (PLC). Materials and Methods: A total of 500 students, from two universities in the Chaoshan area of China, were randomly divided into an intervention group of 280 participants and a control group of 220. Baseline knowledge of HCC and hepatitis B was evaluated by questionnaire interview. Subsequently, only the intervention group was given an information leaflet of HCC and hepatitis B. Three months later, the two groups were contacted for a second interview. Changes in knowledge from baseline of HCC and hepatitis B were compared between the two groups. Results: There was no statistically significant difference in mean PRE-questionnaire scores between the intervention and control groups. However, the mean POST-questionnaire score was significantly higher in the intervention group after the intervention. The leaflet had the greatest effect on the participants' questionnaire score, and raised their level of knowledge about HCC and hepatitis B. Conclusions: The information leaflet intervention is significantly effective in improving the knowledge of HCC and hepatitis B among the youth.

Device-to-Device Relay Cooperative Transmission Based on Network Coding

( Jing Wang ),( Mingsheng Ouyang ),( Wei Liang ),( Jun Hou ),( Xiangyang Liu ) 한국인터넷정보학회 2017 KSII Transactions on Internet and Information Syst Vol.11 No.7

Due to the advantages of low transmit power consumption, high spectral efficiency and extended system coverage, Device-to-Device (D2D) communication has drawn explosive attention in wireless communication field. Considering that intra-cell interference caused between cellular signals and D2D signals, in this paper, a network coding-based D2D relay cooperative transmission algorithm is proposed. Under D2D single-hop relay transmission mode, cellular interfering signals can be regarded as useful signals to code with D2D signals at D2D relay node. Using cellular interfering signals and network coded signals, D2D receiver restores the D2D signals to achieve the effect of interference suppression. Theoretical analysis shows that, compared with Amplify-and-forward (AF) mode and Decode-and-forward (DF) mode, the proposed algorithm can dramatically increase the link achievable rate. Furthermore, simulation experiment verifies that by employing the proposed algorithm, the interference signals in D2D communication can be eliminated effectively, and meanwhile the symbol error rate (SER) performance can be improved.

One-Pot Synthesis of Platinum Nanodendrites with Enhanced Catalytic Performance for Methanol Oxidation Reaction

Shenshen Ouyang,Linfei Wang,Jing Cui,Haibo Shi,Tao Wang,Sheng Wang 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2015 NANO Vol.10 No.7

Controlling the synthesis of noble metal nanostructures with highly branched morphology to obtain specific physical and chemical properties has attracted much attention. This paper reports the synthesis of 3D Pt nanodendrites with controlled architectures (multibranched) by a simple one-pot hydrothermal reaction in the presence of fructose. At high reaction temperature, fructose not only acts as a reducing agent, but also forms a hydrothermal carbon, which, as a capping agent, is absorbed on the surface of metal nanocrystals and induces the anisotropic growth of Pt nanodendrites. The prepared Pt nanodendrites are highly porous, and have self-supported nanoarchitectures with a high surface area and a number of absorption sites for reactant molecules. The Pt nanodendrites exhibit a higher electrocatalytic activity and stability than commercial Pt/C for methanol oxidation reaction.

Inpatients' Knowledge about Primary Liver Cancer and Hepatitis

He, Wen-Jing,Xu, Ming-Yan,Xu, Rui-Rui,Zhou, Xiao-Qiong,Ouyang, Jun-Jie,Han, Hui,Chen, Geng-Zhen Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.8

Objective: To assess the level of an inpatient population's awareness about hepatitis and primary liver cancer (PLC), the most common type of which is hepatocellular carcinoma (HCC), and then to initiate education of this group. Methods: A survey was conducted with 1300 participants within the inpatient unit in representative tertiary hospitals in the Chaoshan area of China. Structured questionnaires contained demographic data and statements about different aspects of liver cancer and hepatitis. The questionnaires were completed by trained medical practitioners after they had conducted the interviews. Results: One way ANOVA showed that the sample population lacked adequate knowledge about HCC and hepatitis. Stepwise multiple regression analysis demonstrated that the participant's level of education had the greatest impact on their total knowledge score when other variables remained constant. Conclusions: The study demonstrated: a general lack of awareness amongst the participants about the preventative strategies, and the management options available for people with primary liver cancer and hepatitis; education level was an important factor affecting knowledge levels. The demonstrated deficiencies in people's knowledge about hepatitis and HCC, and their lack of subsequent protective behaviours are likely to play an important role in HCC and hepatitis transmission or prevention.

Fabrication and Conductive Performance of Antimony-Doped Tin Oxide-Coated Halloysite Nanotubes

Huilin Lun,Jing Ouyang,Aidong Tang,Huaming Yang 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2015 NANO Vol.10 No.6

Antimony-doped tin oxide (ATO) was deposited on the surface of halloysite nanotubes (HNTs) to obtain conductive composite ATO/HNTs by a hydrolysis precipitation process. Structure and morphology of the samples were systematically characterized by X-ray diffraction (XRD), thermogravimetry – differential scanning calorimetry (TG – DSC), transmission electron micro-scope (TEM), energy-dispersive spectrometer (EDS) and Fourier transform infrared (FTIR) spectroscopy. The results indicated that ATO nanoparticles were successfully coated as thin layers on the surface of halloysite and the particle size was ~7.4 nm when calcined at 700℃. The ATO/HNTs composites were obtained with a resistivity of ~430Ω · cm under the optimum experimental parameters. ATO layers were proved to attach to the halloysite surface via the Sn–O–Si or Sn–O–Al bonds. A corresponding coating mechanism was depicted.

Genome-wide identification of long noncoding RNA genes and their potential association with mammary gland development in water buffalo

Jin Yuhan,Ouyang Yina,Fan Xinyang,Huang Jing,Guo Wenbo,Miao Yongwang 아세아·태평양축산학회 2022 Animal Bioscience Vol.35 No.11

Objective: Water buffalo, an important domestic animal in tropical and subtropical regions, play an important role in agricultural economy. It is an important source for milk, meat, horns, skin, and draft power, especially its rich milk that is the great source of cream, butter, yogurt, and many cheeses. In recent years, long noncoding RNAs (lncRNAs) have been reported to play pivotal roles in many biological processes. Previous studies for the mammary gland development of water buffalo mainly focus on protein coding genes. However, lncRNAs of water buffalo remain poorly understood, and the regulation relationship between mammary gland development/milk production traits and lncRNA expression is also unclear. Methods: Here, we sequenced 22 samples of the milk somatic cells from three lactation stages and integrated the current annotation and identified 7,962 lncRNA genes. Results: By comparing the lncRNA genes of the water buffalo in the early, peak, and late different lactation stages, we found that lncRNA gene lnc-bbug14207 displayed significantly different expression between early and late lactation stages. And lnc-bbug14207 may regulate neighboring milk fat globule-EGF factor 8 (MFG-E8) and hyaluronan and proteoglycan link protein 3 (HAPLN3) protein coding genes, which are vital for mammary gland development. Conclusion: This study provides the first genome-wide identification of water buffalo lncRNAs and unveils the potential lncRNAs that impact mammary gland development. Objective: Water buffalo, an important domestic animal in tropical and subtropical regions, play an important role in agricultural economy. It is an important source for milk, meat, horns, skin, and draft power, especially its rich milk that is the great source of cream, butter, yogurt, and many cheeses. In recent years, long noncoding RNAs (lncRNAs) have been reported to play pivotal roles in many biological processes. Previous studies for the mammary gland development of water buffalo mainly focus on protein coding genes. However, lncRNAs of water buffalo remain poorly understood, and the regulation relationship between mammary gland development/milk production traits and lncRNA expression is also unclear.Methods: Here, we sequenced 22 samples of the milk somatic cells from three lactation stages and integrated the current annotation and identified 7,962 lncRNA genes.Results: By comparing the lncRNA genes of the water buffalo in the early, peak, and late different lactation stages, we found that lncRNA gene <i>lnc-bbug14207</i> displayed significantly different expression between early and late lactation stages. And <i>lnc-bbug14207</i> may regulate neighboring milk fat globule-EGF factor 8 (<i>MFG-E8</i>) and hyaluronan and proteoglycan link protein 3 (<i>HAPLN3</i>) protein coding genes, which are vital for mammary gland development.Conclusion: This study provides the first genome-wide identification of water buffalo lncRNAs and unveils the potential lncRNAs that impact mammary gland development.

GBA inhibition suppresses ovarian cancer growth, survival and receptor tyrosine kinase AXL-mediated signaling pathways

Gang Wang,Baisha Ouyang,Fang Jing,Xiaoyan Dai 대한약리학회 2023 The Korean Journal of Physiology & Pharmacology Vol.27 No.1

The poor outcome of advanced ovarian cancer under conventional therapy necessitates new strategies to improve therapeutic efficacy. β-glucosidase (encoded by GBA) is a lysosomal enzyme and is involved in sphingolipids metabolism. Recent studies revealed that β-glucosidase plays a role in cancer development and chemoresistance. In this work, we systematically evaluated the expression and role of GBA in ovarian cancer. Our work demonstrates that inhibition of β-glucosidase has therapeutic potential for ovarian cancer. Gene Expression Profiling Interactive Analysis database, western blot and immunohistochemistry analyses of patient samples demonstrated that GBA mRNA and protein expression levels were significantly increased in ovarian cancer compared to normal tissues. Functional studies using gainof- function and loss-of-function approaches demonstrated that GBA overexpression did not affect growth and migration but alleviated cisplatin’s efficacy in ovarian cancer cells. In addition, GBA depletion resulted in growth inhibition, apoptosis induction, and enhancement of cisplatin’s efficacy. Of note, we found that GBA inhibition specifically decreased receptor tyrosine kinase AXL level, leading to the suppression of AXL-mediated signaling pathways. Our data suggest that GBA represents a promising target to inhibit AXL signaling and overcome cisplatin resistance in ovarian cancer.

Phase lag compensation for improving the stability of LCL‑type converters under weak grid condition

Jianfeng Wang,Guobing Pan,Jing Ouyang,Chengyao Liu,Yinghao Zhou,Gong Fei 전력전자학회 2022 JOURNAL OF POWER ELECTRONICS Vol.22 No.5

LCL-type converters are widely used in the sustainable energy generation system due to their flexible current control strategies and high efficiency. The LCL filter has a resonance peak, which needs to be handled appropriately; otherwise, it causes system instability. Single-loop feedback control strategy is very popular at present; it does not require additional sensors to measure the state variables for active damping. Under weak grid condition, the resonance peak of LCL filter shifts to the left evidently and greatly reduces the stability margin; thus, maintaining the stability of single-loop control is a challenging task. This paper presents an improved grid current feedback (GCF) single-loop control strategy, which is designed to raise the stability margin of system to adapt weak grid condition. Low pass filter controller is used for phase lag compensation. A phase margin design method is proposed to ensure system stability, and the corresponding discrete method in z-domain has been proposed in detail. Experiments performed on a three-phase converter platform are finally presented to verify the effectiveness of the proposed phase lag compensation for GCF control strategy.

Plasma treatment of multi-walled carbon nanotubes for lipase immobilization

Xun Cao,Rui Zhang,Wei-min Tan,Ce Wei,Jing Wang,Ze-meng Liu,Ke-quan Chen,Ping-Kai Ouyang 한국화학공학회 2016 Korean Journal of Chemical Engineering Vol.33 No.5

Plasma-modified multiwalled carbon nanotubes (MWNTs) were used as a support to immobilize lipase. The effects of vacuum plasma treatment power, vacuum plasma treatment time, immobilization temperature, immobilization time, and initial protein concentration of the lipase on the amount of lipase immobilized and on the subsequent activity of the immobilized lipase were investigated. The results showed that the adsorption capacity of the plasma-modified MWNTs could reach 0.15 g/g and that the maximal enzyme activity of the immobilized lipase was 520U/g under optimized conditions. Fourier transform infrared (FTIR) analysis and transmission electron microscopy (TEM) were used to characterize the properties of the plasma-modified MWNTs and plasma-modified MWNTslipase, and the results showed that the lipase was successfully immobilized on the plasma-modified MWNTs. Also, the MWNTs-lipase produced an esterification rate of approximately 47% in the synthesis of polyethylene glycol (PEG)-aliphatic esters.

Surface polished of bulk methylammonium lead tribromide single crystal

Zhang Hang,Zhang Bohao,Wang Xiang,Shao Wenyi,Nie Jing,Liu Jun,Ouyang Xiaoping,Xu Qiang 한국물리학회 2020 Current Applied Physics Vol.20 No.10

Organic-inorganic halide perovskite materials have been demonstrated with wide applications in optoelectronics and ionization radiation detection. For bulk as-grown crystals, the existence of surface cracks and defects can significantly increase charges recombination and reduce the performance of the device. Herein, we polished the crystal surfaces with both mechanical and chemical mechanical methods at room temperature. After been chemical-mechanical polished, the crystal surface with root mean square roughness about 0.5 nm was obtained. Optical transmission and photoluminescence spectra indicate that chemical mechanical polishing technology can effectively reduce the density of crystal surface defects. The achieved low leakage current density on the surface and bulk crystal is 0.05 nA mm 2 and 0.07 nA mm 2, respectively. Furthermore, the current-voltage curve under visible photons and X-ray photons reveals that surface polishing treatment can suppress the charges recombination and increase the charges transportation.