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      • SCOPUSKCI등재

        Effects of surfactants on the remediation of petroleum contaminated soil and surface hydrophobicity of petroleum hydrocarbon degrading flora

        Jianbo Liu,Liming Xu,Feifei Zhu,Shouhao Jia 대한환경공학회 2021 Environmental Engineering Research Vol.26 No.5

        It has been proven that surfactants used in the remediation of petroleum hydrocarbon contaminated soil have great application potential. In this study, the effects of five surfactants (SDBS, Tween80, Tween60, rhamnolipid and TRS-1) on leaching of petroleum hydrocarbons from soil were investigated through orthogonal experiments, and petroleum hydrocarbon components were analyzed by GC/MS. The effects of surfactants on the degradation of petroleum hydrocarbon were analyzed by the changes of microbial growth curve and surface hydrophobicity. The results showed that surfactant type, temperature and surfactant concentration had significant effects on the removal rate of petroleum hydrocarbon. Tween80, rhamnolipid and TRS-1 have good bio-friendliness and a high removal rate of petroleum hydrocarbons (up to 65%), suitable for the restoration of the soil used in the experiment And Surfactants exhibited a higher removal rate for small molecules and petroleum hydrocarbons with odd carbon atoms. Surfactants have a certain modification effect on the surface of relatively hydrophilic bacteria under the initial conditions, making their surface properties develop in the direction of enhanced hydrophobicity, and the hydrophobicity has increased from less than 20% to about 40%.

      • KCI등재

        Chinese Society of Allergy and Chinese Society of Otorhinolaryngology-Head and Neck Surgery Guideline for Chronic Rhinosinusitis

        Zheng Liu,Jianjun Chen,Lei Cheng,Huabin Li,Shixi Liu,Hongfei Lou,Jianbo Shi,Ying Sun,Dehui Wang,Chengshuo Wang,Xiangdong Wang,Yongxiang Wei,Weiping Wen,Pingchang Yang,Qintai Yang,Gehua Zhang,Yuan Zhan 대한천식알레르기학회 2020 Allergy, Asthma & Immunology Research Vol.12 No.2

        The current document is based on a consensus reached by a panel of experts from the Chinese Society of Allergy and the Chinese Society of Otorhinolaryngology-Head and Neck Surgery, Rhinology Group. Chronic rhinosinusitis (CRS) affects approximately 8% of Chinese adults. The inflammatory and remodeling mechanisms of CRS in the Chinese population differ from those observed in the populations of European descent. Recently, precision medicine has been used to treat inflammation by targeting key biomarkers that are involved in the process. However, there are no CRS guidelines or a consensus available from China that can be shared with the international academia. The guidelines presented in this paper cover the epidemiology, economic burden, genetics and epigenetics, mechanisms, phenotypes and endotypes, diagnosis and differential diagnosis, management, and the current status of CRS in China. These guidelines—with a focus on China—will improve the abilities of clinical and medical staff during the treatment of CRS. Additionally, they will help international agencies in improving the verification of CRS endotypes, mapping of eosinophilic shifts, the identification of suitable biomarkers for endotyping, and predicting responses to therapies. In conclusion, these guidelines will help select therapies, such as pharmacotherapy, surgical approaches and innovative biotherapeutics, which are tailored to each of the individual CRS endotypes.

      • KCI등재

        Facile Synthesis of Cu/Cu2O Nanoparticles–Graphene Composites for Efficient Detection of NO2 at Room Temperature

        Xin Liu,Jianbo Sun 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2016 NANO Vol.11 No.9

        Cu/Cu2O nanoparticles-reduced graphene oxide composites (CuGCs) have been successfully prepared by a facile solvothermal method. The combined characterizations indicate the successful formation of CuGCs. The ~3 nm Cu/Cu2O nanoparticles homogeneously in situ grow on reduced graphene oxide sheets. CuGCs-based gas sensors were investigated for detection of NO2 at room temperature. The CuGCs exhibited fast response behavior, relatively high response and could achieve a detection limit as low as 5 ppm. Furthermore, sensing mechanism and the reason for enhancing sensing performance have also been discussed.

      • SCIESCOPUSKCI등재

        Effects of processing method on the pharmacokinetics and tissue distribution of orally administered ginseng

        Chen, Jianbo,Li, Meijia,Chen, Lixue,Wang, Yufang,Li, Shanshan,Zhang, Yuwei,Zhang, Lei,Song, Mingjie,Liu, Chang,Hua, Mei,Sun, Yinshi The Korean Society of Ginseng 2018 Journal of Ginseng Research Vol.42 No.1

        Background: The use of different methods for the processing of ginseng can result in alterations in its medicinal properties and efficacy. White ginseng (WG), frozen ginseng (FG), and red ginseng (RG) are produced using different methods. WG, FG, and RG possess different pharmacological properties. Methods: WG, FG, and RG extracts and pure ginsenosides were administered to rats to study the pharmacokinetics and tissue distribution characteristics of the following ginsenosides-DRg1, Re, Rb1, and Rd. The concentrations of the ginsenosides in the plasma and tissues were determined using UPLC-MS/MS. Results: The rate and extent of absorption of Rg1, Re, Rb1, and Rd appeared to be affected by the different methods used in processing the ginseng samples. The areas under the plasma drug concentration-time curves (AUCs) of Rg1, Re, Rb1, and Rd were significantly higher than those of the pure ginsenosides. In addition, the AUCs of Rg1, Re, Rb1, and Rd were different for WG, FG, and RG. The amounts of Rg1, Re, Rd, and Rb1 were significantly (p < 0.05) higher in the tissues than those of the pure ginsenosides. The amounts of Re, Rb1, and Rd from the RG extract were significantly higher than those from the WG and FG extracts in the heart, lungs, and kidneys of the rats. Conclusion: Our results show that the use of different methods to process ginseng might affect the pharmacokinetics and oral bioavailability of ginseng as well as the tissue concentrations of Rg1, Re, Rd, and Rb1.

      • Research on Analysis Model of Soybean Straw Component

        Weizheng Shen,Jianbo Wang,Qingming Kong,Jing Guan,Jin Cui,Ziqing Liu 보안공학연구지원센터 2015 International Journal of Multimedia and Ubiquitous Vol.10 No.6

        To achieve the rapid detection of soybean straw component, the key lies in establishing a quantitative analysis model with higher prediction accuracy which is rapid, stable and reliable. In order to establish the optimal Near-infrared (NIR) analysis model of cellulose and hemicellulose content in soybean straw, this paper uses NIR transmission technology by applying interval Partial Least Squares (iPLS) on the optimization of characteristic spectrum range of cellulose and hemicellulose spectrum. During the optimized characteristic spectrum range, prediction models of Partial Least Squares Regression (PLSR) and the Back Propagation Neural Network (BPNN) are built in the cellulose and hemicellulose contents respectively. The results show that the best modeling band of the Cellulose content is 5615-5731cm-1, and the optimal coefficient of determination of prediction model, PredictionR2(P-R2) reaches 0.9179266; And the best modeling band of the hemicellulose content is 5615-5731cm-1 ,the P-R2 is 0.920407. After the selection of iPLS optimal band, the quantitative analysis model of cellulose and hemicelluloses established by adopting the PLSR and BP Neural Network is more concise and has higher prediction accuracy and faster data computing speed. It also provides a theoretical basis for the optimization of characteristic spectrum range for the design of small dedicated NIR analytical instruments.

      • KCI등재

        Detection of Myocardial Metabolic Abnormalities by 18F-FDG PET/CT and Corresponding Pathological Changes in Beagles with Local Heart Irradiation

        Rui Yan,Jianbo Song,Zhifang Wu,Min Guo,Jianzhong Liu,Jianguo Li,Xinzhong Hao,Sijin Li 대한영상의학회 2015 Korean Journal of Radiology Vol.16 No.4

        To determine the efficacy of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) in the detection of radiation-induced myocardial damage in beagles by comparing two pre-scan preparation protocols as well as to determine the correlation between abnormal myocardial FDG uptake and pathological findings. The anterior myocardium of 12 beagles received radiotherapy locally with a single X-ray dose of 20 Gy. 18F-FDG cardiac PET/CT was performed at baseline and 3 months after radiation. Twelve beagles underwent two protocols before PET/CT: 12 hours of fasting (12H-F), 12H-F followed by a high-fat diet (F-HFD). Regions of interest were drawn on the irradiation and the non-irradiation fields to obtain their maximal standardized uptake values (SUVmax). Then the ratio of the SUV of the irradiation to the non-irradiation fields (INR) was computed. Histopathological changes were identified by light and electron microscopy. Using the 12H-F protocol, the average INRs were 1.18 ± 0.10 and 1.41 ± 0.18 before and after irradiation, respectively (p = 0.021). Using the F-HFD protocol, the average INRs were 0.99 ± 0.15 and 2.54 ± 0.43, respectively (p < 0.001). High FDG uptake in irradiation field was detected in 33.3% (4/12) of 12H-F protocol and 83.3% (10/12) of F-HFD protocol in visual analysis, respectively (p = 0.031). The pathology of the irradiated myocardium showed obvious perivascular fibrosis and changes in mitochondrial vacuoles. High FDG uptake in an irradiated field may be related with radiation-induced myocardial damage resulting from microvascular damage and mitochondrial injury. An F-HFD preparation protocol used before obtaining PET/CT can improve the sensitivity of the detection of cardiotoxicity associated with radiotherapy.

      • KCI등재

        Combined Use of Automatic Tube Voltage Selection and Current Modulation with Iterative Reconstruction for CT Evaluation of Small Hypervascular Hepatocellular Carcinomas: Effect on Lesion Conspicuity and Image Quality

        Peijie Lv,Jie Liu,Rui Zhang,Yan Jia,Jianbo Gao 대한영상의학회 2015 Korean Journal of Radiology Vol.16 No.3

        To assess the lesion conspicuity and image quality in CT evaluation of small (≤ 3 cm) hepatocellular carcinomas (HCCs) using automatic tube voltage selection (ATVS) and automatic tube current modulation (ATCM) with or without iterative reconstruction. One hundred and five patients with 123 HCC lesions were included. Fifty-seven patients were scanned using both ATVS and ATCM and images were reconstructed using either filtered back-projection (FBP) (group A1) or sinogram-affirmed iterative reconstruction (SAFIRE) (group A2). Forty-eight patients were imaged using only ATCM, with a fixed tube potential of 120 kVp and FBP reconstruction (group B). Quantitative parameters (image noise in Hounsfield unit and contrast-to-noise ratio of the aorta, the liver, and the hepatic tumors) and qualitative visual parameters (image noise, overall image quality, and lesion conspicuity as graded on a 5-point scale) were compared among the groups. Group A2 scanned with the automatically chosen 80 kVp and 100 kVp tube voltages ranked the best in lesion conspicuity and subjective and objective image quality (p values ranging from < 0.001 to 0.004) among the three groups, except for overall image quality between group A2 and group B (p = 0.022). Group A1 showed higher image noise (p = 0.005) but similar lesion conspicuity and overall image quality as compared with group B. The radiation dose in group A was 19% lower than that in group B (p = 0.022). CT scanning with combined use of ATVS and ATCM and image reconstruction with SAFIRE algorithm provides higher lesion conspicuity and better image quality for evaluating small hepatic HCCs with radiation dose reduction.

      • KCI등재

        Anti-thrombotic activity of phenolic acids obtained from Salvia miltiorrhiza f. alba in TNF-a-stimulated endothelial cells via the NF-kB/JNK/p38 MAPK signaling pathway

        Xianjing Zheng,Haimei Liu,Maoqiang Ma,Jianbo Ji,Faliang Zhu,Longru Sun 대한약학회 2021 Archives of Pharmacal Research Vol.44 No.4

        Over the past 100 years, Salvia miltiorrhiza f. alba (Lamiaceae) (RSMA) roots have been used to curethromboangiitis obliterans (TAO) in local clinics. This studyaimed to confi rm the anti-thrombotic effi cacy of 12 phenolicacids obtained from RSMA and to clarify the possibleunderlying mechanisms. The results of quantitative real-timepolymerase chain reaction (qRT-PCR) and enzyme-linkedimmunosorbent assay (ELISA) experiments demonstratedthat most of the phenolic acids markedly inhibited PAI-1protein and mRNA levels but increased t-PA protein andmRNA levels in TNF-α-induced EA.hy926 cells ( P < 0.05or 0.001), with lithospermic acid displaying the strongesteff ect. In vitro anticoagulation and antiplatelet aggregationassays showed that lithospermic acid and salvianolic acidB signifi cantly prolonged prothrombin time (PT), activatedpartial thromboplastin time (APTT), decreased fi brinogen concentration (FIB), and inhibited platelet aggregationinduced by adenosine diphosphate (ADP) in rat blood. Bothlithospermic acid and salvianolic acid B markedly down-regulatedthe expression of factor Xa and factor IIa on the externalsurface of EA.hy926 cells and demonstrated signifi cantanti-factor IIa and anti-factor Xa activity using chromogenicsubstrates in vitro. Western blot results revealed that bothlithospermic acid and salvianolic acid B also signifi cantlyinhibited the expression of TF, p-p65, p-p38, and pJNK proteinsinduced by TNF-α. These results indicated that all ofthe phenolic acids appeared to have some anti-thromboticactivity, with salvianolic acid B and lithospermic acid markedlydecreasing the chance of thrombosis by regulating theNF-κB/JNK/p38 MAPK signaling pathway in response toTNF-α.

      • KCI등재

        Experimental and Analytical Study of Eccentrically Braced Frames Combined with High-Strength Steel

        Shen Li,Yunhe Liu,JianBo Tian 한국강구조학회 2018 International Journal of Steel Structures Vol.18 No.2

        In the structure of high-strength steel composite eccentrically braced steel frames (HSS–EBFs), the links and braces are made of Q345 steel, while the non-energy-dissipation segments (columns and beams) are made of high-strength steel (HSS). HSS reduces the cross-section of the members and increases the economic effi ciency. Here, four groups of K-HSS–EBFs are designed by performance-based plastic design method in this paper, which includes 5-storey, 10-storey, 15-storey and 20-storey, and each group contain four diff erent link length (900, 1000, 1100 and 1200 mm). The cyclic test loading was applied to 1:2 scale three-storey K-type HSS–EBFs (K-HSS–EBFs) with shear links to investigate their seismic performance. The results indicate that the as-prepared K-HSS–EBF structure exhibits excellent bearing capacity, ductility, and energy dissipation. We also fi nd that the fracture of the link web in the second storey led to the degradation of the load-carrying capacity. The non-designated yield members remained in the elastic stage, whereas the links ultimately experience inelastic rotations, and thus dissipate the energy in the K-HSS–EBFs. Moreover, nonlinear pushover analyses and nonlinear dynamic analyses are conducted, and the loading capacity, link rotations, ductility, interstory drifts and failure mode under rare earthquake of all models are compared. The results indicate that K-HSS–EBFs with diff erent link length have similar deformation characteristic and failure mode under pushover analysis or rare earthquakes, and the interstory drifts, link rotations and ductility of HSS–EBFs are increased with rising the link length.

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