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Sung-Ryong Ko,Kang-Ju Choi,Byung-Goo Cho,Kil-Bong Nho,Seok-Chang Kim,Byeong-Seon Jeon and Chun-Suk 고려인삼학회 2005 Journal of Ginseng Research Vol.29 No.3
Ginseng saponins have been known as main active principles and are quantified as the index components of ginseng and its products for quality control. However ginseng saponins are easily hydrolyzed in acidic solutions of crude drug preparations. Due to the hydrolysis of saponins in acidic condition, it is generally difficult to determine ginseng saponins in crude drug preparations. Ginseng saponins, prosapogenins and sapogenins of crude drug extracts were quantified by HPLC. Ginseng saponins were quantified by HPLC on Lichrosorb-NH₂ column with acetonitrile/water/1-butanol(80:20:10, v/v). Ginseng prosapogenin-Rg₃ and -Rg₂ were extracted with ethyl acetate from 50% acetic acid hydrolyzates of saponin fractions and quantified by HPLC on Lichrosorb-NH₂ column with acetonitrile/water(90:10, v/v). Ginseng sapogenins, panaxadiol and panaxatriol, were extracted with diethyl ether from 7%-sulfuric acid hydrolyzates of saponin fractions and quantified by HPLC on μ-Bondapak C18 column with acetonitrile/methanol/chloroform(83:10:7, v/v). These methods of analyses of sapogenins and prosapogenins were more useful for quality control than those of ginseng saponins in some of crude drug preparations.
Sang-Chip Lee,Kee-Young Jeon,Seung-Hwan Lee,Bong-Hwan Oh,Hoon-Goo Lee,Kyung-Hee Han 전력전자학회 2004 ICPE(ISPE)논문집 Vol.- No.-
This paper estimates a coefficient of adhesion through speed sensor-less vector control and load torque disturbance observer for controlling maximum tractive force, and also proposes anti-slip control algorithm, which controls torque force of motor in order to keep the estimated adhesion force in maximum adhesion by controlling PI torque with the differential value of estimated adhesion force coefficient.
Modeling and Motion Control of Mobile Robot for Lattice Type Welding
Jeon, Yang-Bae,Kim, Sang-Bong The Korean Society of Mechanical Engineers 2002 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.16 No.1
This paper presents a motion control method and its simulation results of a mobile robot for a lattice type welding. Its dynamic equation and motion control methods for welding speed and seam tracking are described. The motion control is realized in the view of keeping constant welding speed and precise target line even though the robot is driven for following straight line or curve. The mobile robot is modeled based on Lagrange equation under nonholonomic constraints and the model is represented in state space form. The motion control of the mobile robot is separated into three driving motions of straight locomotion, turning locomotion and torch slider control. For the torch slider control, the proportional-integral-derivative (PID) control method is used. For the straight locomotion, a concept of decoupling method between input and output is adopted and for the turning locomotion, the turning speed is controlled according to the angular velocity value at each point of the corner with range of 90$^{\circ}$ constrained to the welding speed. The proposed control methods are proved through simulation results and these results have proved that the mobile robot has enough ability to apply the lattice type welding line.
Sang Ki Lee,Young Shin Kim,Cuk Seong Kim,Sook Jin Son,Dae Goon Yoo,Kwon Ho Lee,Sang Do Lee,Jin Bong Park,Byeong Hwa Jeon 대한생리학회-대한약리학회 2006 The Korean Journal of Physiology & Pharmacology Vol.10 No.3
Among the Shc proteins, p66shc is known to be related to oxidative stress responses and regulation of the production of reactive oxygen species (ROS). The present study was undertaken to investigate the role of p66shc on endothelial nitric oxide synthase (eNOS) activity in the mouse embryonic fibroblasts (MEFs). When wild type (WT) or p66shc (/) MEFs were transfected with full length of eNOS cDNA, the expression and activity of eNOS protein were higher in the p66shc (/) MEFs. These phenomena were reversed by reconstitution of p66shc cDNA transfection in the p66shc (/) MEFs. The basal superoxide production in the p66shc (/) MEFs was not significantly different from that of WT of MEFs. However, superoxide production induced by NADPH in the p66shc (/) MEF was lesser than that in WT MEFs. When compared with WT MEFs, cell lysate of p66shc (/) MEFs showed significantly increased H-ras activity without change of endogenous H-ras expression. Our findings suggest the pivotal role of p66shc adaptor protein played in inhibition of endothelial nitric oxide production via modulation of the expression and/or activity of eNOS protein.
Sang Bong Lee,Ho Won Lee,Bobby Aditya Darmawan,In-Kyu Lee,Sung Jin Cho,Jungwook Chin,Sang Kyoon Kim,Jong-Oh Park,Kil Soo Kim,Sang-Woo Lee,Jaetae Lee,Yong Hyun Jeon 한국공업화학회 2020 Journal of Industrial and Engineering Chemistry Vol.88 No.-
We report the fabrication of multifunctional theranositic biomaterials via non-covalent, rapid, andeffective encapsulation of 1,10dioctadecyl-3,3,30,30-tetrametylindotrucarbocyanine iodide (DIR)onto mesoporous silica nanoparticles by coating the surface of polyethylene glycol (PEG-DIR@MSN). PEG-DIR@MSNs exhibited great stability with excellent biocompatibility and photothermal conversionproperties. PEG-DIR@MSN allowed for not only the detection of various types of tumor and ischemiclesions but also photothermal therapy against breast cancer in living mice, suggesting that PEGDIR@MSN is a valuable multifunctional theranostic platform.