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      • KCI등재

        Long-term assessment of periodontal disease progression after surgical or non-surgical treatment: a systematic review

        Ignacio Sanz-Martín,Jae-Kook Cha,윤성욱,Ignacio Sanz-Sánchez,정의웅 대한치주과학회 2019 Journal of Periodontal & Implant Science Vol.49 No.2

        The primary aim of this systematic review was to assess the evidence on periodontal disease progression after treatment in patients receiving supportive periodontal therapy (SPT) and to identify predictors of clinical attachment level (CAL) loss. A protocol was developed to answer the following focused question: In adult patients treated for periodontitis, what is the disease progression in terms of CAL loss after surgical or non-surgical treatment? Randomized controlled clinical trials, prospective cohort studies, and longitudinal observational human studies with a minimum of 5 years of follow-up after surgical or non-surgical treatment that reported CAL and probing depth changes were selected. Seventeen publications reporting data from 14 investigations were included. Data from 964 patients with a follow-up range of 5–15 years was evaluated. When the CAL at the latest follow-up was compared to the CAL after active periodontal therapy, 10 of the included studies reported an overall mean CAL loss of ≤0.5 mm, 3 studies reported a mean CAL loss of 0.5–1 mm, and 4 studies reported a mean CAL loss of >1 mm. Based on 7 publications, the percentage of sites showing a CAL loss of ≥2 mm varied from 3% to 20%, and a high percentage of sites with CAL loss was associated with poor oral hygiene, smoking, and poor compliance with SPT. The outcomes after periodontal therapy remained stable over time. Disease progression occurred in a reduced number of sites and patients, mostly associated with poor oral hygiene, poor compliance with SPT, and smoking.

      • "Do they see me as a Professional?”: Narratives of an Early Childhood Teacher in the Context of COVID-19 Pandemic

        Figueroa-Céspedes Ignacio(Figueroa-Céspedes Ignacio),Guerra Paula(Guerra Paula) The Pacific Early Childhood Education Research Ass 2024 Asia-Pacific journal of research in early childhoo Vol.18 No.1

        This article analyses the experience of a Chilean early childhood (EC) teacher in the context of the COVID-19 pandemic. Part of a broader qualitative and narrative research, this article is a case study based on her professional experience during the pandemic. The results reveal four phases in the process: (1) initial confusion, (2) proposal, (3) disappointment and action, (4) balance and dialogue. The narrative shows a series of situations experienced by the EC teacher in her relationship with the children’s families, where identity negotiation emerged linked to the revalidation of her professional role. In addition, developing teaching and collaborative skills to respond to emergency situations is highlighted. Based on this experience, the need to elicit cultural changes that articulate care and pedagogical fields in EC education in Chile is analysed.

      • SCIESCOPUSKCI등재

        Long-term assessment of periodontal disease progression after surgical or non-surgical treatment: a systematic review

        Sanz-Martin, Ignacio,Cha, Jae-Kook,Yoon, Sung-Wook,Sanz-Sanchez, Ignacio,Jung, Ui-Won Korean Academy of Periodontology 2019 Journal of Periodontal & Implant Science Vol.49 No.2

        The primary aim of this systematic review was to assess the evidence on periodontal disease progression after treatment in patients receiving supportive periodontal therapy (SPT) and to identify predictors of clinical attachment level (CAL) loss. A protocol was developed to answer the following focused question: In adult patients treated for periodontitis, what is the disease progression in terms of CAL loss after surgical or non-surgical treatment? Randomized controlled clinical trials, prospective cohort studies, and longitudinal observational human studies with a minimum of 5 years of follow-up after surgical or non-surgical treatment that reported CAL and probing depth changes were selected. Seventeen publications reporting data from 14 investigations were included. Data from 964 patients with a follow-up range of 5-15 years was evaluated. When the CAL at the latest follow-up was compared to the CAL after active periodontal therapy, 10 of the included studies reported an overall mean CAL loss of ${\leq}0.5mm$, 3 studies reported a mean CAL loss of 0.5-1 mm, and 4 studies reported a mean CAL loss of >1 mm. Based on 7 publications, the percentage of sites showing a CAL loss of ${\geq}2mm$ varied from 3% to 20%, and a high percentage of sites with CAL loss was associated with poor oral hygiene, smoking, and poor compliance with SPT. The outcomes after periodontal therapy remained stable over time. Disease progression occurred in a reduced number of sites and patients, mostly associated with poor oral hygiene, poor compliance with SPT, and smoking.

      • KCI등재

        Unilateral Cervical Facet Fractures: Relevance of Acute Disc Injury in Conservative Treatment Failure

        Totera Juan Ignacio Cirillo,Vargas Gabriel Hernández,Martini Ignacio Farías,Romero Marcos Gimbernat,Bacciarini Alejandro Urzúa,Plaza José Vicente Ballesteros 대한척추외과학회 2023 Asian Spine Journal Vol.17 No.1

        Study Design: Case-control study. Purpose: Analyze association between imaging factors related to the failure of conservative treatment in isolated subaxial cervical facet fractures. Overview of Literature: Facet fracture (F1, F2, and F3 AOSpine) may be stable or unstable depending on clinical and imaging variables, which are not well established. As a result, differences in fracture management lead to differences in surgical or conservative indications, and there is no evidence to predict conservative treatment failure. Methods: Patients were categorized into two groups: six patients (16.2%) with conservative treatment failure (defined as the appearance of neurological symptoms, listhesis >3.5 mm, kyphotic deformation >11°, and/or non-union), and 31 patients (83.7%) with successful conservative management (defined as complete consolidation confirmed by computed tomography [CT] at the 6-month follow-up). All participants were fitted with rigid collars of the Miami type, and standardized follow-up was performed until consolidation or failure. CT and magnetic resonance imaging (MRI) was used to examine imaging characteristics. Sagittal balance parameters were assessed using CT, and signs of acute disc injury, prevertebral edema, facet synovitis, and interspinous hyperintense signal were assessed using MRI. Results: Thirty-seven patients were diagnosed with unilateral cervical facet fractures between 2009 and 2020. In this sample, acute disc injury had a significative association to failure of conservative treatment in F2 and F3 AOSpine facet fractures, 100% of the failure group presented with traumatic disc injury compared to 9.7% of the successful group, for the other variables: prevertebral edema, 83.7% vs. 41.9%; facet synovitis, 100% vs. 77.4%; and interspinous hyperintensity, 71.4% vs. 38.7%, respectively. With conservative management, all F1 fractures healed successfully. Conservative treatment failed in 20% of F2 fractures and 50% of F3 fractures, respectively. In terms of cervical sagittal balance parameters, there were no significant differences between groups. Conclusions: Conservative management was successful in all F1 fractures. In F2 and F3 types, there was a significant association between acute disc injury and conservative treatment failure.

      • KCI등재

        Pulmonary Embolism from Cement Augmentation of the Vertebral Body

        Jose Manuel Fernando Ignacio,Katrina Hannah Dizon Ignacio 대한척추외과학회 2018 Asian Spine Journal Vol.12 No.2

        Pulmonary cement embolism (PCE) can follow cement augmentation procedures for spine fractures due to osteoporosis, traumatic injuries, and painful metastatic lesions. PCE is underreported and it is likely that many cases remain undiagnosed. Risk factors for PCE have been identified, which can help alert clinicians to patients likely to develop the condition, and there are recommended techniques to reduce its incidence. Most patients with PCE are asymptomatic or only develop transient symptoms, although a few may exhibit florid cardiorespiratory manifestations which can ultimately be fatal. Diagnosis is mainly by radiographic means, commonly using simple radiographs and computed tomography scans of the chest with ancillary tests that assess the patient’s cardiorespiratory condition. Management depends on the location and size of the emboli as well as the patient’s symptomatology. The aim of this review is to raise awareness of the not uncommon complications of PCE following vertebral cement augmentation and the possibility of serious sequelae. Recommendations for the diagnosis and management of PCE are presented, based on the most recent literature.

      • KCI등재
      • SCIESCOPUSKCI등재

        Bioprocess and Metabolic Engineering : Improved Production of Medium-Chain-Length Polyhydroxyalkanoates in Glucose-Based Fed-Batch Cultivations of Metabolically Engineered Pseudomonas putida Strains

        ( Ignacio Poblete Castro ),( Andre Luis Rodriguez ),( Carolyn Ming Chi Lam ),( Wolfgang Kessler ) 한국미생물 · 생명공학회 2014 Journal of microbiology and biotechnology Vol.24 No.1

        One of the major challenges in metabolic engineering for enhanced synthesis of value-added chemicals is to design and develop new strains that can be translated into well-controlled fermentation processes using bioreactors. The aim of this study was to assess the influence of various fed-batch strategies in the performance of metabolically engineered Pseudomonas putida strains, Δgcd and Δgcd-pgl, for improving production of medium-chain-length polyhydroxyalkanoates (mcl-PHAs) using glucose as the only carbon source. First we developed a fed-batch process that comprised an initial phase of biomass accumulation based on an exponential feeding carbon-limited strategy. For the mcl-PHA accumulation stage, three induction techniques were tested under nitrogen limitation. The substrate-pulse feeding was more efficient than the constant-feeding approach to promote the accumulation of the desirable product. Nonetheless, the most efficient approach for maximum PHA synthesis was the application of a dissolved-oxygen-stat feeding strategy (DO-stat), where P. putida Δgcd mutant strain showed a final PHA content and specific PHA productivity of 67% and 0.83 g·l-1·h-1, respectively. To our knowledge, this mcl-PHA titer is the highest value that has been ever reported using glucose as the sole carbon and energy source. Our results also highlighted the effect of different fed-batch strategies upon the extent of realization of the intended metabolic modification of the mutant strains.

      • KCI등재

        Augmented reality and dynamic infrared thermography for perforator mapping in the anterolateral thigh

        Ignacio Javier Cifuentes,Bruno Leonardo Dagnino,María Carolina Salisbury,María Eliana Perez,Claudia Ortega,Daniela Maldonado 대한성형외과학회 2018 Archives of Plastic Surgery Vol.45 No.3

        Dynamic infrared thermography (DIRT) has been used for the preoperative mapping of cutaneous perforators. This technique has shown a positive correlation with intraoperative findings. Our aim was to evaluate the accuracy of perforator mapping with DIRT and augmented reality using a portable projector. For this purpose, three volunteers had both of their anterolateral thighs assessed for the presence and location of cutaneous perforators using DIRT. The obtained image of these “hotspots” was projected back onto the thigh and the presence of Doppler signals within a 10-cm diameter from the midpoint between the lateral patella and the anterior superior iliac spine was assessed using a handheld Doppler device. Hotspots were identified in all six anterolateral thighs and were successfully projected onto the skin. The median number of perforators identified within the area of interest was 5 (range, 3–8) and the median time needed to identify them was 3.5 minutes (range, 3.3–4.0 minutes). Every hotspot was correlated to a Doppler sound signal. In conclusion, augmented reality can be a reliable method for transferring the location of perforators identified by DIRT onto the thigh, facilitating its assessment and yielding a reliable map of potential perforators for flap raising.

      • KCI등재

        Synthesis and characterization of Rh/Al2O3-CeO2 catalysts: effect of the Ce4+/Ce3+ ratio on the MTBE removal

        Ignacio Cuauhtémoc,Gilberto Torres,Juan Navarrete,Carlos Angeles-Chavez,Juan Manuel Padilla,Gloria Del Angel 한양대학교 세라믹연구소 2009 Journal of Ceramic Processing Research Vol.10 No.4

        Rhodium supported catalysts were prepared by impregnating γ-Al2O-Ce supports, which were prepared from boehmite and cerium nitrate with different cerium contents (1, 5, 10 and 20 Ce wt%). High specific surface areas, which diminish with the cerium content, were obtained. At high cerium contents the X-ray Diffraction (XRD) patterns showed the characteristic peaks of cerium oxide. X-ray photoelectron Spectroscopy (XPS) identified the presence of Rho and Rhδ+ on the catalysts. The analysis of the Ce 3d region showed the presence of Ce3+ and Ce4+ where their relative abundance depends on the cerium content. Small rhodium particle sizes were determined by High Angle Annular Dark Field (HAADF) Scanning Transmission Electron Microscopy (STEM). It has been found that the conversion for the wet oxidation of methyl tert-butyl ether (MTBE) depends on the cerium content; conversion ranging from 73 to 96% were reached. A correlation between the total mineralization of MTBE and the relative abundance of the Ce4+/Ce3+ ratio was observed. A total mineralization, as high as 87%, was obtained in the catalyst with the highest Ce4+/Ce3+ ratio. Rhodium supported catalysts were prepared by impregnating γ-Al2O-Ce supports, which were prepared from boehmite and cerium nitrate with different cerium contents (1, 5, 10 and 20 Ce wt%). High specific surface areas, which diminish with the cerium content, were obtained. At high cerium contents the X-ray Diffraction (XRD) patterns showed the characteristic peaks of cerium oxide. X-ray photoelectron Spectroscopy (XPS) identified the presence of Rho and Rhδ+ on the catalysts. The analysis of the Ce 3d region showed the presence of Ce3+ and Ce4+ where their relative abundance depends on the cerium content. Small rhodium particle sizes were determined by High Angle Annular Dark Field (HAADF) Scanning Transmission Electron Microscopy (STEM). It has been found that the conversion for the wet oxidation of methyl tert-butyl ether (MTBE) depends on the cerium content; conversion ranging from 73 to 96% were reached. A correlation between the total mineralization of MTBE and the relative abundance of the Ce4+/Ce3+ ratio was observed. A total mineralization, as high as 87%, was obtained in the catalyst with the highest Ce4+/Ce3+ ratio.

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