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Isolation of Angiotensin Converting Enzyme Inhibitors from Ripe Cucurbita moschata Duch
Hyeyoung Jung,Kyung Bin Song 한국식품영양과학회 2001 Preventive Nutrition and Food Science Vol.6 No.4
Angiotensin converting enzyme (ACE) inhibitor acts on the inhibition of ACE, causes a decrease in blood pressure. There have been several reports on screening of ACE inhibitors from natural food products, protein hydrolysates of various food sources. Ripe Cucurbita moschata Duch has been used as an oriental medicine in Korea. To isolate ACE inhibitors, crude water extracts of the edible portion of ripe Cucurbita moschata Duch were obtained after heating in water at 95℃ for 2 h. Crude extracts were then filtered using PM-10, YM-1 membranes. The membrane-filtered solution was loaded onto Sephadex G-15 column equlibrated with a phosphate buffer. Among the four major fractions of gel permeation chromatography, the second fraction had the highest inhibitory activity of 65%. Further purification of the fraction using reversed-phase HPLC with a C18 column produced ACE inhibitors, which were identified as a mixture having molecular mass of 222, 273 by Tandem mass spectrometry.
Early outcome of the Korean Diagnosis-Related Groups payment system for appendectomy
Hyeyoung Kim,In Mok Jung,Keong Won Yun,Seung Chul Heo,Young Joon Ahn,Ki-Tae Hwang,Hae Won Lee,Do Hoon Koo,Eunyoung Ko,Hye Seong Ahn,Rumi Shin,Jung Kee Chung 대한외과학회 2015 Annals of Surgical Treatment and Research(ASRT) Vol.88 No.3
Purpose: The implementation of the Korean diagnosis-related groups (DRG) payment system has been recently introduced in selected several diseases including appendectomy in Korea. Here, we report the early outcomes with regard to clinical aspects and medical costs of the Korean DRG system for appendectomies in Seoul Metropolitan Government ? Seoul National University Boramae Medical Center throughout comparing before and after introduction of DRG system. Methods: The DRG system was applied since January 2013 at our institute. After the DRG system, we strategically designed and applied our algorithm for the treatment of probable appendicitis. We reviewed the patients who were treated with a procedure of appendectomy for probable appendicitis between July 2012 and June 2013, divided two groups based on before and after the application of DRG system, and compared clinical outcomes and medical costs. Results: Total 416 patients were included (204 patients vs. 212 patients in the group before vs. after DRG). Shorter hospital stays (2.98 ± 1.77 days vs. 3.82 ± 1.84 days, P < 0.001) were found in the group after DRG. Otherwise, there were no significant differences in the perioperative outcomes and medical costs including costs for first hospitalization and operation, costs for follow-up after discharge, frequency of visits of out-patient’s clinic or Emergency Department or rehospitalization. Conclusion: In the Korean DRG system for appendectomy, there were no significant differences in perioperative outcomes and medical costs, except shorter hospital stay. Further studies should be continued to evaluate the current Korean DRG system for appendectomy and further modifications and supplementations are needed in the future.
정혜영(Jung hyeyoung),김미진(Kim Mijin) 학습자중심교과교육학회 2021 학습자중심교과교육연구 Vol.21 No.6
본 연구는 은유 분석을 통해 유아교사의 유아관찰에 대한 인식을 살펴보고자 하는데 그 목적이 있다. 연구참여자는 유아교육기관에 재직 중인 교사 155명이며, 자료수집은 유아관찰에 대한 메타포와 그 이유를 작성하도록 구성되어 있는 개방형 설문지를 사용하여 온라인 설문조사를 통해 이루어졌다. 수집된 자료는 메타포 명명, 메타포의 분류 및 제거, 메타포의 표본 추출과 범주화, 평정자 간 신뢰도 확인의 4단계 절차로 분석되었다. 연구결과, 131개의 메타포는 본다는 것, 유아 이해, 관찰의 관점, 교육의 기본, 어려움, 교사 성장의 과정, 평가를 위한 업무의 7가지 범주로 분석되었다. 유아교사들이 유아관찰에 대해 가지고 있는 다양한 시선과 실천을 분석하고, 관찰의 의미, 관점, 목적, 어려움 등의 측면에서 유아관찰의 한계와 방향성을 논하였다. The purpose of this study is to examine the perception of early childhood teachers on observing young children through metaphor analysis. The study participants consisted of 155 teachers in early childhood education institutions, and data were collected through an open-ended questionnaire that was composed to fill out metaphors and reasons for children observation. The collected data were analyzed in four steps: naming/labeling stage, clarification and elimination stage, sample metaphor compilation and categorization stage, and establishing the inter-rater reliability rate stage. As a result of the study, 131 metaphors were analyzed into 7 categories of seeing, understanding of children, viewpoint of observation, basics of education, difficulties, the process of teacher growth, and work for evaluation. The various perspectives and practices of early childhood teachers observations were analyzed, and the limitations and directions of children observation were discussed in terms of the meaning, viewpoint, purpose, and difficulty of observation.