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      • KCI등재

        Production performances and antioxidant activities of laying hens fed Aspergillus oryzae and phytase co-fermented wheat bran

        Huang Chung Ming,Chuang Wen Yang,Lin Wei Chih,Lin Li Jen,Chang Sheng Chang,Lee Tzu Tai 아세아·태평양축산학회 2021 Animal Bioscience Vol.34 No.3

        Objective: Wheat bran (WB) was co-fermented with Aspergillus oryzae and phytase (Phy) to determine whether co-fermentation improve WB phosphorus and fiber utilization in Isa-brown layers. Methods: A total of 112 Isa brown layer were randomly divided into 7 treatments with 8 replicates per a treatment and 2 hens per a replicate. The treatments included basal diet (control), basal diet supplemented with 250 unit/kg Phy (control+Phy), diet with 10% WB (10% WB), diet with 5% WB and 250 unit/kg Phy (5% WB+Phy) diet with 10% WB and 250 unit/kg Phy (10% WB+Phy), diet with 5% fermented WB supplemented with molasses and phy (PCFWH) and 125 unit/kg Phy (5% PCFWH), and diet with 10% PCFWH (10% PCFWH). The intestinal microbial population, intestinal morphology, serum antioxidant enzyme activities, and excreta phosphorus content were assessed. Results: In PCFWH, spore counts, protease activity, xylanase activity, and ferulic acid were 8.50 log/g dry matter (DM), 190 unit/g DM, 120 unit/g DM, and 127 μg/g, respectively. Xylobiose and xylotriose were released in PCFWH, while they were not detectable in WB. Antioxidant capacity was also enhanced in PCFWH compared to WB. The 10% WB+Phy and 10% PCFWH groups produced higher egg mass, but hens fed 5% WB+Phy had the lowest amount of feed intake. Eggs from 10% PCFWH had better eggshell weight, eggshell strength, and eggshell thickness. Birds fed with 10% PCFWH also had higher serum superoxide dismutase and catalase activities. Compare to control, 10% PCFWH significantly reduced excreta phosphorus content. Conclusion: Diet inclusion of 10% PCFWH improved egg quality, antioxidant status, and excreta phosphorus content of laying hens. Objective: Wheat bran (WB) was co-fermented with Aspergillus oryzae and phytase (Phy) to determine whether co-fermentation improve WB phosphorus and fiber utilization in Isa-brown layers.Methods: A total of 112 Isa brown layer were randomly divided into 7 treatments with 8 replicates per a treatment and 2 hens per a replicate. The treatments included basal diet (control), basal diet supplemented with 250 unit/kg Phy (control+Phy), diet with 10% WB (10% WB), diet with 5% WB and 250 unit/kg Phy (5% WB+Phy) diet with 10% WB and 250 unit/kg Phy (10% WB+Phy), diet with 5% fermented WB supplemented with molasses and phy (PCFWH) and 125 unit/kg Phy (5% PCFWH), and diet with 10% PCFWH (10% PCFWH). The intestinal microbial population, intestinal morphology, serum antioxidant enzyme activities, and excreta phosphorus content were assessed.Results: In PCFWH, spore counts, protease activity, xylanase activity, and ferulic acid were 8.50 log/g dry matter (DM), 190 unit/g DM, 120 unit/g DM, and 127 μg/g, respectively. Xylobiose and xylotriose were released in PCFWH, while they were not detectable in WB. Antioxidant capacity was also enhanced in PCFWH compared to WB. The 10% WB+Phy and 10% PCFWH groups produced higher egg mass, but hens fed 5% WB+Phy had the lowest amount of feed intake. Eggs from 10% PCFWH had better eggshell weight, eggshell strength, and eggshell thickness. Birds fed with 10% PCFWH also had higher serum superoxide dismutase and catalase activities. Compare to control, 10% PCFWH significantly reduced excreta phosphorus content.Conclusion: Diet inclusion of 10% PCFWH improved egg quality, antioxidant status, and excreta phosphorus content of laying hens.

      • KCI등재

        No-Reference Image Quality Assessment Using Independent Component Analysis and Convolutional Neural Network

        Chuang Zhang,Jiawei Xu,Xiaoyu Huang,박형섭 대한전기학회 2019 Journal of Electrical Engineering & Technology Vol.14 No.1

        As digital images have become a significantly primary medium in a broad area, there is a growing interest in the development of automatic objective image quality assessment (IQA) methods. In this paper, a novel no-reference IQA (NRIQA) algorithm is proposed based on independent component analysis and convolutional neural network. The proposed NRIQA algorithm consists of the following three steps: selection of some representative patches, extraction of the features of the selected image patches, and prediction of the image quality by exploiting the features. Initially, an image is divided into non-overlapping patches and then some patches are selected with the suitable property for assessing the overall image quality. In this paper, we refer to the selected patches as image quality patches. The largest infinity norm of the gradient of each image quality patch is employed as a basis when the image quality patches being selected. Second, we employ independent component analysis (ICA) to extract the features of image quality patches. At the last moment, a convolutional neural network (CNN) is applied to the independent component coefficients of image quality patches to predict the corresponding differential mean opinion score (DMOS). We compared the performance of the proposed NQIRM with other IQMs in terms of PCC, SROCC, and RMSE on the database LIVE2, CSIQ and TID2008/2013. The PCC, SROCC and RMSE values achieve respectively to 0.996, 0.999 and 6.011 on the database TID2013. The performance comparison results show the proposed NRIQM is superior to commonly used IQMs.

      • Keratanase II Digestion Accompanied with a Liquid Chromatography/Tandem Mass Spectrometry for Urinary Keratan Sulfate Quantitative Analysis

        Chuang, Chih-Kuang,Lin, Hsiang-Yu,Wang, Tuen-Jen,Huang, Sung-Fa,Lin, Shuan-Pei Association for Research of MPS and Rare Diseases 2017 Journal of mucopolysaccharidosis and rare disease Vol.3 No.1

        Purpose: Mucopolysaccharidosis IV (MPS IV) is a disease characterized by deficient activity of N-acetylgalactosamine-6-sulfatase (GALNS) causing excessive lysosomal storage of keratan sulfate (KS). The identification of the relevant disaccharide units of KS after keratanase II digestion followed by liquid chromatography/tandem mass spectrometry detection (LC-MS/MS) is validated and applicable for the preliminary diagnosis of MPS IV. Methods: A total of 67 urine samples were collected and analyzed from 11 MPS IV patients comprising 10 MPS IVA and one MPS IVB patients, and 56 normal controls. Urinary glycosaminoglycan was first precipitated by the Alcian blue method followed by a digestion of keratanase II. The protonated species of the digested disaccharide products were detected by using multiple reaction monitoring experiment. Results: One particular disaccharide of KS was selected. The transition mass-to-charge (m/z) of the parent ion and its daughter ion after collision was $462.0{\rightarrow}97.0$, whereas the chondrosine used as an internal standard in this assay was m/z $353.9{\rightarrow}73.0$. The results corresponded well with the two-dimensional electrophoresis method. The quantities of urinary KS were significantly raised in confirmed MPS IV patients when comparing with those of normal controls ($170.2{\pm}81.1$ vs. $4.06{\pm}1.92{\mu}g/mL$). Conclusion: The LC-MS/MS method for MPS IVA determination is specific, sensitive, validated, and applicable for urinary KS quantification. This method can be used not only as a first-line biochemistry examination of MPS IVA, but also as an outcome survey after enzyme replacement therapy.

      • SCOPUSKCI등재

        Synthesis of Praseodymium-Doped TiO<sub>2</sub> Nanocatalysts by Sol-Microwave and Their Photocatalytic Activity Study

        Huang, Fengping,Wang, Shuai,Zhang, Shuang,Fan, Yingge,Li, Chunxue,Wang, Chuang,Liu, Chun Korean Chemical Society 2014 Bulletin of the Korean Chemical Society Vol.35 No.8

        The praseodymium-doped $TiO_2$ photocatalyst samples, which could degrade methyl orange under UV irradiation, were prepared by sol-microwave method for improving the photocatalytic activity of $TiO_2$. The resulting materials were analyzed by X-ray diffraction (XRD), scanning electron microscopy (SEM), Transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), Raman spectra, Fourier transform infrared spectra (FTIR) and Ultraviolet-visible diffuse reflectance spectra (UV-vis DRS). It was found Pr doping retarded the growth of crystalline size and the phase transformation from anatase to rutile, and narrowed the band gap energy. Praseodymium doping brought about remarkable improvement in the photoactivity. The optimal dopant amount of Pr was 2% by molar of cement and the calcination temperature was $500^{\circ}C$ for the best photocatalytic activity. The improvement of photocatalytic activity was ascribed to the occurrence of lattice distortion and the effective containment of the recombination of the electron-hole by $Pr^{3+}$.

      • Quantitative Assessment the Relationship between p21 rs1059234 Polymorphism and Cancer Risk

        Huang, Yong-Sheng,Fan, Qian-Qian,Li, Chuang,Nie, Meng,Quan, Hong-Yang,Wang, Lin Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.10

        p21 is a cyclin-dependent kinase inhibitor, which can arrest cell proliferation and serve as a tumor suppressor. Though many studies were published to assess the relationship between p21 rs1059234 polymorphism and various cancer risks, there was no definite conclusion on this association. To derive a more precise quantitative assessment of the relationship, a large scale meta-analysis of 5,963 cases and 8,405 controls from 16 eligible published case-control studies was performed. Our analysis suggested that rs1059234 was not associated with the integral cancer risk for both dominant model [(T/T+C/T) vs C/C, OR=1.00, 95% CI: 0.84-1.18] and recessive model [T/T vs (C/C+C/T), OR=1.03, 95% CI: 0.93-1.15)]. However, further stratified analysis showed rs1059234 was greatly associated with the risk of squamous cell carcinoma of head and neck (SCCHN). Thus, larger scale primary studies are still required to further evaluate the interaction of p21 rs1059234 polymorphism and cancer risk in specific cancer subtypes.

      • KCI등재

        A Generative Adversarial Network to Denoise Depth Maps for Quality Improvement of DIBR-Synthesized Stereoscopic Images

        Zhang Chuang,Sun Xian-wen,Xu Jiawei,Huang Xiao-yu,Yu Gui-yue,Park Seop Hyeong 대한전기학회 2021 Journal of Electrical Engineering & Technology Vol.16 No.4

        Depth map quality is an important factor that aff ects the quality of synthesized stereoscopic images in stereoscopic visual communication systems using the depth image-based rendering (DIBR) technique. This paper proposes a method using a generative adversarial network (GAN) to denoise depth maps corrupted by several types of distortion. The generative network of the proposed GAN builds on convolutional layers, residual layers, and transposed convolutional layers with symmetric skip connections. The discriminative network of the proposed GAN is designed as a convolutional neural network. The generative network for denoising depth maps is trained with cropped depth maps where distortion is applied. Objective and subjective assessment of denoised depth maps and DIBR-synthesized stereoscopic images demonstrate that the proposed GAN eff ectively reduces the distortion in the depth maps and improves the quality of DIBR-synthesized stereoscopic images.

      • Study on the Innovation of Talent Cultivation Mode in Universities under the Background of the Construction of Double City Economic Circle

        况,迎春(Chuang Yingchun),高雅(Gao Ya),黄,怡(Huang Yi),阳,丹(Yang Dan),吕,瑶,(Lu Yao),唐慧(Tang Hu),李青,嵩(Li Qing-Song) 아시아사회과학학회 2022 International Science Research Vol.2 No.1

        成渝双城经济圈作为国家重要的协同发展战略, 对成渝地区教育、人才培养发展、人才联育方面, 提供了历史性的机遇, 人才作为社会、国家重要的发展动力, 对于实现民族振兴、赢得国际竞争主动权的战略资源具有重要作用。本文立足于成渝双城经济圈政策实行的大背景下, 深入探讨实现人才创新发展的路径与基础, 在切实分析成渝双城经济圈高校人才培养模式现状后, 通过结合成渝地区重点高校报告和相关数据进行比较研究, 提出所面临的缺陷与不足等相关问题的合理可行的建议。 As an important national cooperative development strategy, Chengdu Chongqing double city economic circle provides a historic opportunity for education, talent training and development, and Talent Association in Chengdu-Chongqing area. As an important driving force for social and national development, talent plays an important role in realizing national revitalization and winning the strategic resources of international competition initiative. Based on the background of the implementation of the policy of Chengdu Chongqing double city economic circle, this paper deeply explores the path and basis for the development of talent innovation. After the actual analysis of the current situation of the talent training mode in Chengdu Chongqing double city economic circle, through the comparison of the report of key universities in Chengdu-Chongqing area and related data, it puts forward reasonable and feasible suggestions on the defects and deficiencies faced and other related issues.

      • KCI등재
      • KCI등재

        Surgical Outcomes and Predictive Factors in Patients With Detrusor Underactivity Undergoing Bladder Outlet Obstruction Surgery

        Ming-Syun Chuang,Yin-Chien Ou,Yu-Sheng Cheng,Kuan-Yu Wu,Chang-Te Wang,Yuan-Chi Huang,Yao-Lin Kao 대한배뇨장애요실금학회 2024 International Neurourology Journal Vol.28 No.1

        Purpose: This study was conducted to evaluate the efficacy of bladder outlet surgery in patients with detrusor underactivity (DU) and to identify factors associated with successful outcomes.Methods: We conducted a retrospective review of men diagnosed with DU in urodynamic studies who underwent bladder outlet surgery for lower urinary tract symptoms between May 2018 and April 2023. The International Prostate Symptom Score (IPSS) questionnaire, uroflowmetry (UFM), and multichannel urodynamic studies were administered. Successful treatment outcomes were defined as either an IPSS improvement of at least 50% or the regaining of spontaneous voiding in patients urethral catheterization prior to surgery.Results: The study included 93 male patients. Men diagnosed with significant or equivocal bladder outlet obstruction (BOO) experienced significant postoperative improvements in IPSS (from 20.6 to 6.0 and from 17.4 to 6.5, respectively), maximum urine flow rate (from 5.0 mL/sec to 14.4 mL/sec and from 8.8 mL/sec to 12.2 mL/sec, respectively) and voiding efficiency (from 48.8% to 86.0% and from 61.2% to 85.1%, respectively). However, in the group without obstruction, the improvements in IPSS and UFM results were not significant. The presence of detrusor overactivity (odds ratio [OR], 3.152; P=0.025) and preoperative urinary catheterization (OR, 2.756; P=0.040) were associated with favorable treatment outcomes. Conversely, an unobstructed bladder outlet was identified as a negative prognostic factor.Conclusions: In men with DU accompanied by equivocal or significant BOO, surgical intervention to alleviate the obstruction may enhance the IPSS, quality of life, and UFM results. However, those with DU and an unobstructed bladder outlet face a comparatively high risk of treatment failure. Preoperative detrusor overactivity and urinary catheterization are associated with more favorable surgical outcomes. Consequently, active deobstructive surgery should be considered for patients with DU who are experiencing urinary retention. Purpose: This study was conducted to evaluate the efficacy of bladder outlet surgery in patients with detrusor underactivity (DU) and to identify factors associated with successful outcomes. Methods: We conducted a retrospective review of men diagnosed with DU in urodynamic studies who underwent bladder outlet surgery for lower urinary tract symptoms between May 2018 and April 2023. The International Prostate Symptom Score (IPSS) questionnaire, uroflowmetry (UFM), and multichannel urodynamic studies were administered. Successful treatment outcomes were defined as either an IPSS improvement of at least 50% or the regaining of spontaneous voiding in patients urethral catheterization prior to surgery. Results: The study included 93 male patients. Men diagnosed with significant or equivocal bladder outlet obstruction (BOO) experienced significant postoperative improvements in IPSS (from 20.6 to 6.0 and from 17.4 to 6.5, respectively), maximum urine flow rate (from 5.0 mL/sec to 14.4 mL/sec and from 8.8 mL/sec to 12.2 mL/sec, respectively) and voiding efficiency (from 48.8% to 86.0% and from 61.2% to 85.1%, respectively). However, in the group without obstruction, the improvements in IPSS and UFM results were not significant. The presence of detrusor overactivity (odds ratio [OR], 3.152; P=0.025) and preoperative urinary catheterization (OR, 2.756; P=0.040) were associated with favorable treatment outcomes. Conversely, an unobstructed bladder outlet was identified as a negative prognostic factor. Conclusions: In men with DU accompanied by equivocal or significant BOO, surgical intervention to alleviate the obstruction may enhance the IPSS, quality of life, and UFM results. However, those with DU and an unobstructed bladder outlet face a comparatively high risk of treatment failure. Preoperative detrusor overactivity and urinary catheterization are associated with more favorable surgical outcomes. Consequently, active deobstructive surgery should be considered for patients with DU who are experiencing urinary retention.

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