Quantitative Assessment of the Diagnostic Role of CDH13 Promoter Methylation in Lung Cancer

Zhong, Yun-Hua,Peng, Hao,Cheng, Hong-Zhong,Wang, Ping Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.3

In order to explore the association between cadherin 13 (CDH13) gene promoter methylation and lung carcinoma (LC) risk, we carried out a meta-analysis with searching of PubMed, Web of Science. Ultimately, 17 articles were identified and analysised by STATA 12.0 software. Overall, we found a significant relationship between CDH13 promoter methylation and LC risk (odds ratio=6.98, 95% confidence interval: 4.21-11.56, p<0.001). Subgroup analyses further revealed that LC risk was increased for individuals carrying the methylated CDH13 compared with those with unmethylated CDH13. Hence, our study identified a strong association between CDH13 gene promoter methylation and LC and highlighted a promising potential for CDH13 methylation in LC risk prediction.

Design and Performance Analysis of Networked Predictive Control Systems Based on Input-Output Difference Equation Model

Zhong-Hua Pang,Guo-Ping Liu,Donghua Zhou,Dehui Sun 제어·로봇·시스템학회 2017 International Journal of Control, Automation, and Vol.15 No.1

This paper is concerned with the design and performance analysis of networked control systems, whererandom network-induced delay, packet disorder, and packet dropout in the feedback and forward channels areconsidered simultaneously and further treated as the round-trip time (RTT) delay. To actively compensate forthe RTT delay, a networked predictive control scheme is designed based on the input-output difference equationmodel. For time-varying reference signals, the resulting closed-loop system can achieve the same output trackingperformance and closed-loop stability as the corresponding local control system. Specifically, for the step referenceinput, it can provide a zero steady-state output tracking error. The controller design problem is solved by usingthe augmented state-space model as well as the static output feedback strategy. In addition, the stability of theclosed-loop system is also discussed for the plant subject to bounded disturbances and modelling errors. Finally,simulation and experimental results are given to demonstrate the effectiveness of the proposed method.

Wafer-scale synthesis of monolayer two-dimensional porphyrin polymers for hybrid superlattices

Zhong, Yu,Cheng, Baorui,Park, Chibeom,Ray, Ariana,Brown, Sarah,Mujid, Fauzia,Lee, Jae-Ung,Zhou, Hua,Suh, Joonki,Lee, Kan-Heng,Mannix, Andrew J.,Kang, Kibum,Sibener, S. J.,Muller, David A.,Park, Jiwoon American Association for the Advancement of Scienc 2019 Science Vol.366 No.6471

<P><B>Single-layer porphyrin polymerization</B></P><P>Two-dimensional polymers can be made as monolayer sheets through controlled synthesis at an interface. However, it is often difficult to create intact sheets over large areas that can be transferred onto substrates. Zhong <I>et al.</I> polymerized derivatized porphyrin molecules during laminar flow at a sharp pentane-water interface to form sheets that are 5 centimeters in diameter (see the Perspective by MacLean and Rosei). The authors used electron microscopy and spectroscopy to confirm that they had produced intact monolayers. These films were then transferred onto monolayer sheets of molybdenum disulfide to form superlattices for use as capacitors.</P><P><I>Science</I>, this issue p. 1379; see also p. 1308</P><P>The large-scale synthesis of high-quality thin films with extensive tunability derived from molecular building blocks will advance the development of artificial solids with designed functionalities. We report the synthesis of two-dimensional (2D) porphyrin polymer films with wafer-scale homogeneity in the ultimate limit of monolayer thickness by growing films at a sharp pentane/water interface, which allows the fabrication of their hybrid superlattices. Laminar assembly polymerization of porphyrin monomers could form monolayers of metal-organic frameworks with Cu<SUP>2+</SUP> linkers or covalent organic frameworks with terephthalaldehyde linkers. Both the lattice structures and optical properties of these 2D films were directly controlled by the molecular monomers and polymerization chemistries. The 2D polymers were used to fabricate arrays of hybrid superlattices with molybdenum disulfide that could be used in electrical capacitors.</P>

Using n-Alkanes as Potential Indicators of Degradation in Alpine Meadow

Zhong-Hua DUAN,Xiao-Long QUAN,You-Ming QIAO,Hai-Kun PEI,Gui-Fang HE 한국초지조사료학회 2016 한국초지조사료학회 학술대회논문집 Vol.2016 No.08

Submanifolds of Constant Scalar Curvature in a Space Form

Zhong Hua Hou KYUNGPOOK UNIVERSITY 1998 Kyungpook mathematical journal Vol.38 No.1

Let M^(n) be a closed submanifold immersed into a space formM~^(n+p)_ (c) of constant curvature c≥ 0. Denote by R the normalized scalar curvature and by H the mean curvature of M^(n) : Suppose that R is constant and R≥ c. We firstly extend Cheng-Yau's technique to higher codimension cases. Then we study the rigidity problem for M^(n) with parallel normalized mean curvature vector field. We show that, if H satisfies a certain inequality, then M^(n) is totally umbilical or the equaluity holds. We describe all M^(n) that satisfy this equality. We also prove some rigidity theorems of Yano-Ishihara's type and extend the rigidity theorems of H. Li to higher codimension. 0. Introduction

중국 소수민족 홍요(紅瑤)의 전통 문양을 활용한 티셔츠 디자인

종화림 ( Hua-lim Zhong ),조진숙 ( Jean-suk Cho ) 한국디자인트렌드학회 2009 한국디자인포럼 Vol.24 No.-

본 연구에서 다루고자 하는 홍요(紅瑤)는 중국 소수민족인 요족의 한 분지이다. 홍요의 전통 복식은 매우 화려하며 현대적인 느낌을 주기도 한다. 특히 전통 복식에 나타난 자수 문양은 그 형태가 다양하고 저마다 색다른 품격을 지니고 있어서 고도의 예술적 가치가 높다. 따라서 전통적이면서도 현대적인 미가 표현되어있는 홍요의 전통 문양을 활용하여 현대인이 즐겨 입는 티셔츠를 디자인하고자 한다. 연구방법은 홍요와 관련된 문헌과 논문, 인터넷 사이트 등을 통하여 홍요의 전통 복식과 문양 등에 대해 고찰하고, 디자인 발상과 관련된 문헌과 논문, 패션잡지 등을 참고로 하여 디자인 발상방법 등을 연구하였다. 전통 문양을 활용하여 티셔츠를 디자인하는 발상과정은 문양의 선 정리, 문양의 색채배색, 문양 배치, 티셔츠의 색채 선정 등의 과정을 거쳐서 티셔츠 디자인이 완성되었다. 이처럼 민족 고유의 전통 문양을 모티프로 하여 현대적 디자인으로 재창조하는 일은 패션의 문화적 인식을 함께하며 다양한 디자인의 발상 영역을 넓혀 주는 것으로서 다양한 디자인을 추구하는 디자이너들에게 도움이 될 것으로 사료된다. The Hongyo tribe studied in this paper is a minor ethnic group in china, whose traditional pattern has a high artistic value in that its shapes are diverse and splendid and each one has its own peculiar elegance. In this study, I designed T-shirts, using the Hongyo tribe`s traditional patterns that display both conventional and modern beauty. As for the research method, I examined the Hongyo tribe`s traditional costumes and patterns through related books, research papers, internet sites, and etc. I also examined the method of design conception using reference books, papers and fashion magazines. The procedure of design conception for T-shirts using traditional patterns includes a pattern arrangement, color-matching of patterns, a pattern disposition of T-shirts, and color-matching of T-shirts and patterns. As mentioned above, I recreated the traditional pattern on T-shirts. In way, I hope this study will make a contribution to the field of costume designs.

Comparative Genomics Profiling of Clinical Isolates of Helicobacter pylori in Chinese Populations Using DNA Microarray

Yue-Hua Han,Wen-Zhong Liu,Yao-Zhou Shi,Li-Qiong Lu,Shudong Xiao,Qing-Hua Zhang,Guo-Ping Zhao 한국미생물학회 2007 The journal of microbiology Vol.45 No.1

In order to search for specific genotypes related to this unique phenotype, we used whole genomic DNA microarray to characterize the genomic diversity of Helicobacter pylori (H. pylori) strains isolated from clinical patients in China.The open reading frame (ORF) fragments on our microarray were generated by PCR using gene-specific primers. Genomic DNA of H. pylori 26695 and J99 were used as templates. Thirty-four H. pylori isolates were obtained from patients in Shanghai. Results were judged based on ln(x) transformed and normalized Cy3/Cy5 ratios. Our microarray included 1882 DNA fragments corresponding to 1636 ORFs of both sequenced H. pylori strains. Cluster analysis, revealed two diverse regions in the H. pylori genome that were not present in other isolates. Among the 1636 genes, 1091 (66.7%) were common to all H. pylori strains, representing the functional core of the genome. Most of the genes found in the H. pylori functional core were responsible for metabolism, cellular processes, transcription and biosynthesis of amino acids, functions that are essential to H. pylori’s growth and colonization in its host. In contrast, 522(31.9%) genes were strain-specific genes that were missing from at least one strain of H. pylori. Strainspecific genes primarily included restriction modification system components, transposase genes, hypothetical proteins and outer membrane proteins. These strain-specific genes may aid the bacteria under specific circumstances during their long-term infection in genetically diverse hosts. Our results suggest 34 H. pylori clinical strains have extensive genomic diversity. Core genes and strain-specific genes both play essential roles in H. pylori propagation and pathogenesis. Our microarray experiment may help select relatively significant genes for further research on the pathogenicity of H. pylori and development of a vaccine for H. pylori.

BRI3 associates with SCG10 and attenuates NGF-induced neurite outgrowth in PC12 cells

Yan Hua Gong,Jing Wu,Hua Qiang,Ben Liu,Zhi Kai Chi,Tao Chen,Bin Yin,Xiao Zhong Peng,Jian Gang Yuan 한국생화학분자생물학회 2008 BMB Reports Vol.41 No.4

제11회 한,중 형법 국제 학술심포지엄 : 회사자본제도 변혁 중의 형법보장

샤오종화 ( Zhong Hua Xiao ),쉬판 ( Fan Xu ) 한국비교형사법학회 2013 비교형사법연구 Vol.15 No.2

2005년 개정된 회사법에서는 회사자본제도에 대하여 대대적인 개혁을 실시함으로써 자본제도 완화로의 개혁이라는 국제적인 추세에 순응하게 되었으나, 회사자본제도에 대한 형법의 보호와 회사법 간의 연결에 있어서 채워지기 힘든 균열이 생기게 되었다. 기존의 범죄가 새로운 회사자본제도의 테두리 안에 규정됨에 따라 원래의 보호효과가 점점 퇴색되어가고 있다. 중국 회사자본제도의 형법보호에 대한 입법을 적절하게 조정해야 할것이다. 구체적으로는 등록자 본허위보고죄의 폐지, 허위출자행위의 ‘비범죄화’, 출자도피죄를 회사재산도피죄로 개정, 사기증자죄의 신설 등이 필요하다. As the amending of the company law in 2005 in China, great changes have taken place in the capital system. This reform is consistent with the international trend about the corporate capital. But it increases the gap between the law protect in criminal law and the corporate law. Some criminal provisions cannot protect the corporate capital system availably according to the new company law. The author advocates that the criminal legislation should make corresponding adjustment, which abolishes the crime of false reporting registered capital and the crime of false contributed capital, changes the crime of surreptitious withdrawing the contributed capital into the crime of surreptitious withdrawing the corporate property, and add a new accusation of using fraudulent means to increase corporate capital in the current criminal law.

요족(瑤族)의 전통 복식과 문양

종화림(Hua-Lim Zhong),조진숙(jean-Suk Cho) 한국의상디자인학회 2009 한국의상디자인학회지 Vol.11 No.2