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RISS 인기검색어
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- 저자 : Heedoo Lee (검색결과 5 건)
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이희두(Lee Heedoo) 한국언어문학회 2007 한국언어문학 Vol.63 No.-
The addition of ‘ㅣ’ at the end of the verb final stem, the name of persons and animals were very productive in Middle Korean. However the reason and mechanism of the addition of ‘ㅣ’ were not explicitely explained yet. In this paper I suggested that ‘ㅣ’ was a discourse marker which increased the familiarity and efficiency of a communication. This marker did not change the propositional meaning and the category of part of speech and then I also insisted that it was a linguistic element on the level of a spoken language, not a written language.<BR> This discourse marker was first emerged after the name of persons by way of the grammaticalization of the subject marker ‘ㅣ’. A grammaticalization did expand the grmmatical properties by the change from a lexical status to grammatical status, from a derivational forms to a inflectional forms, from the less grammaticl forms to the more grammatical forms. However all the lexical items were not grammaticized but only a few of the lexical items were according to the usage frequency. On the basis of this point of view, a syntagmatic structure ‘personal name+subject marker ‘ㅣ’’ which had a high usage frequency was grammaticized by a psychological reanalysis and so the concept of grammatical relation of the subject marker was abstractively changed to the familiar relations of the discourse marker.<BR> Whenever this discourse marker ‘ㅣ’ was additioned to the final vowel of stems, a falling dipthongs were appeared owing to the vowel system of that time. Through a 18C this vowel system was drastically changed by a monothongization. As the result of this vowel change the discourse marker ‘ㅣ’ was developed to the feature [fronted] by the more grammaticalization and then this discourse marker feature of the contemporary Korean has been addited to the word initial on the contrary to the Middle Korean.
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이희두(Lee Heedoo) 한국언어문학회 2008 한국언어문학 Vol.65 No.-
In the conjugational form /noh+n?n/→[nonn?n], the phonological process like ‘h→n’ was simply explained as a kind of nasalization coventionally on the basis of a syntagmatic relation of their constituents. The result of ‘n’ in the change ‘h→n’ can directly be derived either by the regressive assimilation to the following nasal sound or by the way of the syllable final neutralization to the alveolar ‘t’ or glottal ‘?’. Moreover it has recently been explained by autosegmental spreading a nasal feature to the empty slot which was produced after deleting ‘h’ and also by the interaction of faithfulness and alignment constraints in the OT. However these previous explanations do not seem to be satisfactory and also do not resolve many problems because their process is unnatural phonologically. Therfore I suggest a new approach on the basis of its prosodic structure. In the view of prosodic points, the change ‘h→n’ will be explained by the gemination of following initial nasal consonant of endings. The phonetic features of laryngeal spread ‘h’ and the mora projection at the level of sentence phonology will have to profoundly be considered in order to understand this phonological phenomena completely. Moraic ‘h’ at the coda has to be licensed by the root node whithin its Feature Geometry. However as this ‘h’ does not have the root node originally, the mora of preceding heterosyllabic coda have insted to govern the following initial consonant of the endings and then gemination will appear.
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안희두(Heedoo An),서만호(Manho Seo),이순천(Sooncheon Lee),정회경(Hoekyung Jung) 한국HCI학회 2018 한국HCI학회 학술대회 Vol.2018 No.1
본 연구팀의 VR 교육 콘텐츠의 실재감(presence)과 상호작용(Interaction)에 따른 교육효과(이해도, 관심도, 재미)를 알아보기 위해 VR 콘텐츠에 대한 실험 연구를 실시하였다. VR 교육 콘텐츠의 재미를 위해서는 실재감을, 이해도를 위해서는 상호작용에 비중을 두어야 하는 것으로 나타났다.
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Particulate matter induces ferroptosis by accumulating iron and dysregulating the antioxidant system
Minkyung Park,Young-Lai Cho,Yumin Choi,Jeong-Ki Min,Young-Jun Park,Sung-Jin Yoon,Dae-Soo Kim,Mi-Young Son,Su Wol Chung,Heedoo Lee,Seon-Jin Lee 생화학분자생물학회 2023 BMB Reports Vol.56 No.2
Particulate matter is an air pollutant composed of various components,and has adverse effects on the human body. Particulatematter is known to induce cell death by generating animbalance in the antioxidant system; however, the underlyingmechanism has not been elucidated. In the present study, wedemonstrated the cytotoxic effects of the size and compositionof particulate matter on small intestine cells. We found thatparticulate matter 2.5 (PM2.5) with extraction ion (EI) components(PM2.5 EI), is more cytotoxic than PM containing only polycyclicaromatic hydrocarbons (PAHs). Additionally, PM-inducedcell death is characteristic of ferroptosis, and includes ironaccumulation, lipid peroxidation, and reactive oxygen species(ROS) generation. Furthermore, ferroptosis inhibitor as liproxstatin-1and iron-chelator as deferiprone attenuated cell mortality, lipidperoxidation, iron accumulation, and ROS production after PM2.5EI treatment in human small intestinal cells. These results suggestthat PM2.5 EI may increase ferroptotic-cell death by ironaccumulation and ROS generation, and offer a potential therapeuticclue for inflammatory bowel diseases in human smallintestinal cells.
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