Differential Protein Expressions in Virus-Infected and Uninfected Trichomonas vaginalis

Ding He,Gong Pengtao,Yang Ju,Li Jianhua,Li He,Zhang Guocai,Zhang Xichen 대한기생충학열대의학회 2017 The Korean Journal of Parasitology Vol.55 No.2

<i>Yersinia pseudotuberculosis</i> Exploits CD209 Receptors for Promoting Host Dissemination and Infection

He, Ying-Xia,Ye, Cheng-Lin,Zhang, Pei,Li, Qiao,Park, Chae Gyu,Yang, Kun,Jiang, Ling-Yu,Lv, Yin,Ying, Xiao-Ling,Ding, Hong-Hui,Huang, Hong-Ping,Mambwe Tembo, John,Li, An-Yi,Cheng, Bing,Zhang, Shu-Sheng American Society for Microbiology 2019 Infection and immunity Vol.87 No.1

<P><I>Yersinia pseudotuberculosis</I> is a Gram-negative enteropathogen and causes gastrointestinal infections. It disseminates from gut to mesenteric lymph nodes (MLNs), spleen, and liver of infected humans and animals.</P><P><I>Yersinia pseudotuberculosis</I> is a Gram-negative enteropathogen and causes gastrointestinal infections. It disseminates from gut to mesenteric lymph nodes (MLNs), spleen, and liver of infected humans and animals. Although the molecular mechanisms for dissemination and infection are unclear, many Gram-negative enteropathogens presumably invade the small intestine via Peyer’s patches to initiate dissemination. In this study, we demonstrate that <I>Y. pseudotuberculosis</I> utilizes its lipopolysaccharide (LPS) core to interact with CD209 receptors, leading to invasion of human dendritic cells (DCs) and murine macrophages. These <I>Y. pseudotuberculosis</I>-CD209 interactions result in bacterial dissemination to MLNs, spleens, and livers of both wild-type and Peyer’s patch-deficient mice. The blocking of the <I>Y. pseudotuberculosis</I>-CD209 interactions by expression of O-antigen and with oligosaccharides reduces infectivity. Based on the well-documented studies in which HIV-CD209 interaction leads to viral dissemination, we therefore propose an infection route for <I>Y. pseudotuberculosis</I> where this pathogen, after penetrating the intestinal mucosal membrane, hijacks the <I>Y. pseudotuberculosis</I>-CD209 interaction antigen-presenting cells to reach their target destinations, MLNs, spleens, and livers.</P>

Modeling Mutual Intraceability of Mobile RFID Systems Using BRS-based Approach

He Jialiang,Ding Jifeng,Xu Xiaoke,Xu Zhiqiang 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.2

Intraceability is the most important aspect of RFID security. Mobile RFID readers are used more and more widely, the privacy of mobile reader privacy holders should be considered. In this paper, a BRS-based approach for modeling mutual intraceability of mobile RFID systems is provided. Elements in a RFID protocol can be represented as bigraphs, communications between elements can be represented as reaction rules. RFID intraceability can be represented as behavioral congruence. We take a RFID air interface protocol for mobile RFID systems as a case study and show the usability of this approach.

Preparation and properties of Nd-doped BCTH lead-free ceramics by solid-phase twin crystal method

He Xiyue,Fang Bijun,Zhang Shuai,Lu Xiaolong,Ding Jianning 한국물리학회 2022 Current Applied Physics Vol.38 No.-

0.5 mol% Nd-doped (Ba0.85Ca0.15)(Ti0.9Hf0.1)O3 (BCTH-Nd) lead-free ceramics were prepared by a solid-phase twin crystal method, where the effects of sintering condition on structure, electrical and optical properties were studied. All the sintered BCTH-Nd ceramics exhibit pure perovskite structure, dense microstructure with several micron grain size, which tends to increase with elevating sintering temperature. All synthesized ceramics have complex dielectric behavior, which presents normal ferroelectrics characteristic with slight dispersion phenomenon. The BCTH-Nd ceramics exhibit excellent piezoelectric and ferroelectric properties and acceptable dielectric performance when sintered at 1480 ◦C for 2 h. Under 269 nm light excitation, several fluorescent emission peaks are excited with a whole indigo fluorescence, where the strongest emission peak is emitted at 473 nm, corresponding to the 4G3/2 → 4I9/2 energy level transition of Nd3+. Multifunctional performance is fulfilled in the lead-free BCTH ceramics via rare earth doping, which can broaden the application fields of piezoelectricbased materials.

Energy-Efficient Power Control for Underlaying D2D Communication with Channel Uncertainty: User-Centric Versus Network-Centric

Ding, Jianfeng,Jiang, Lingge,He, Chen The Korea Institute of Information and Commucation 2016 Journal of communications and networks Vol.18 No.4

Most existing resource management problem models arise from the original desire of allocating resources in either a user-centric or network-centric manner. The difference between their objectives is obvious: user-centric methods attempt to optimize the utility of individual users, whereas network-centric models intend to optimize the collective utilities of the entire network. In this paper, from the above two aspects, we analyze the robust power control problem in device-to-device (D2D) communication underlaying cellular networks, where two types of channel uncertainty set (e.g., ellipsoidal and column-wise) are considered. In the user-centric method, we formulate the problem into the form of a Stackelberg game, where the energy efficiency (EE) of each user is the ingredient of utility function. In order to protect the cellular user equipment's (CUE) uplink transmission, we introduce a price based cost function into the objectives of D2D user equipment (DUE). The existence and uniqueness of the game with the influence of channel uncertainty and price are discussed. In the network-centric method, we aim to maximize the collective EE of CUEs and DUEs. We show that by the appropriate mathematical transformation, the network-centric D2D power control problem has the identical local solution to that of a special case of the user-centric problem, where price plays a key role. Numerical results show the performance of the robust power control algorithms in the user-centric and network-centric models.

Constraints on crust-mantle transition zone with Pn waveforms: A case study of eastern China and southern Korean Peninsula

Ding, Shiban,Ni, Sidao,Kim, YoungHee,He, Xiaohui Elsevier 2019 Physics of the earth and planetary interiors Vol.289 No.-

<P><B>Abstract</B></P> <P>The seismic velocity structure of the crust-mantle transition zone (CMTZ) provides key constraints on crustal dynamics, and can be studied with Pn wave which propagates horizontally along the Moho discontinuity. In this study, we first explore an effect of velocity-gradient structures in the CMTZ through synthetic Pn waveforms, and demonstrate that the shape of Pn changes from step-like to pulse-like when the CMTZ becomes from sharp to a gradient velocity structure, respectively. We then use Pn waveforms of the regional earthquakes (the July 2012 Mw 4.8 earthquake in east China and the September 2016 Mw 5.1 earthquake in South Korea) to examine the CMTZ structures to the west and east of the Yellow Sea and thus to constrain tectonic affinity between the eastern China and southern Korean Peninsula. The Pn waveforms from the Mw 4.8 event in east China show that the Moho in southern Yangtze Craton is sharp whereas there may be a gradient structure in CMTZ with a 6–10 km thickness in northern Yangtze Craton. The Pn waveforms from the Mw 5.1 event in South Korea show that the CMTZ in South Korea is also sharp, similar to the southern Yangtze Craton. Observed difference in CMTZ structures suggest that Sulu Orogenic Belt may extend along the north of the Gyeonggi Massif in Korea.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Pn waveforms are sensitive to the gradients of crust-mantle transition zone (CMTZ). </LI> <LI> Southern Korea features sharp Moho while eastern China Moho shows variability. </LI> </UL> </P>

Computer simulation of 2D grain growth using a cellular automata model based on the lowest energy principle

He, Yizhu,Ding, Hanlin,Liu, Liufa,Shin, Keesam Elsevier 2006 Materials science & engineering. properties, micro Vol.429 No.1

<P><B>Abstract</B></P><P>The morphology, topology and kinetics of normal grain growth in two-dimension were studied by computer simulation using a cellular automata (CA) model based on the lowest energy principle. The thermodynamic energy that follows Maxwell–Boltzmann statistics has been introduced into this model for the calculation of energy change. The transition that can reduce the system energy to the lowest level is chosen to occur when there is more than one possible transition direction. The simulation results show that the kinetics of normal grain growth follows the Burke equation with the growth exponent <I>m</I>=2. The analysis of topology further indicates that normal grain growth can be simulated fairly well by the present CA model. The vanishing of grains with different number of sides is discussed in the simulation.</P>

A New Modulation to Eliminate the Impact of Overlap Time for Three-Phase Current Source Converters

Ding Hao,Guo Xiaoqiang,He Meiling,Shi Changli,Jia Dongqiang,Chen Chao,Guerrero Josep M. 대한전기학회 2022 Journal of Electrical Engineering & Technology Vol.17 No.5

Three-phase current source converter tends to be attractive in future industrial applications. In order to ensure the continuous current for the dc-link inductor of the current source converter (CSC), an overlap time is mandatory for each switch, so as to avoid the over-voltage spike caused by the dc-link inductor current interruption. However, the overlap time results in the undesirable harmonics and current distortion, which fails to comply with the relevant IEEE Standard in terms of power quality. Especially, the negative infl uence caused by overlap time eff ect is much more serious with the increasing of the switching frequency applied to CSC. In order to solve the problem, the impact of the overlap time on the CSC is investigated, and the error resulted from the overlap time is clearly demonstrated. Based on the pulse equivalent principle and the Fourier analysis, the quantitative relationship between the current harmonic and the overlap time is obtained. And then, a new approach to eliminate the impact of overlap time on the CSC is proposed. Finally, the simulation and experimental results are carried out to verify the eff ectiveness of the proposed solution.

Microstructures and Thermal Properties of Polycaprolactone/Epoxy Resin/SiO₂ Hybrids

He, Lihua,Liu, Pinggui,Ding, Heyan The Society of Adhesion and Interface 2006 접착 및 계면 Vol.7 No.4

A series of organic-inorganic hybrids, PCL/EP/$SiO_2$, involving epoxy resin and triethoxysilane-terminated polycaprolactone elastomer (PCL-TESi) were prepared via polymerization of diglycidyl ether of bisphenol A (DGEBA) with amine curing agent KB-2 and sol-gel process of PCL-TESi. The curing reactions were started from the initially homogeneous mixture of DGEBA, KB-2 and the PCL-TESi. The organicinorganic hybrids containing up to 4.95% (wt) of $SiO_2$ were obtained and characterized by FT-IR, transmission electron microscopy (TEM), differential scanning calorimetry (DSC) and thermogravimetry analysis (TGA). It was experimentally shown that the swelling property in toluene, morphologies and thermal properties of the resulting hybrids were quite dependent on the contents of $SiO_2$. The crosslink network density decreases with increasing of the PCL-TESi. And in TEM, the phase separated morphology of these hybrids was found, which resulted from the coagulation of Si-O-Si networks resulting from $-Si(OC_2H_5)_3$ of PCL-TESi self-curing by hydrolytic silanol condensation, with the advancement of the curing reaction in the modified epoxy resin systems. Meanwhile, the change of the $SiO_2$ content made the morphologies changed from aggregated particles of Si-O-Si in the hybrid to nanocluster of interconnected Si-O-Si particles, then to aggregated Si-O-Si dispersing in the continuous cured epoxy phase again, and last to co-continuous interpenetrating network. The glass transition behavior of the hybrid material was cooperative motion of large chain segments, which were hindered by the inorganic Si-O-Si network. And in TG analysis, the characteristic temperature at 5% of weight loss was evidently increased from $120.5^{\circ}C$ of pure cured epoxy to $277.6^{\circ}C$ of 3.84% (wt) of $SiO_2$ modified epoxy due to the existence of Si-O-Si when PCL-TESi was added in the hybrid.

Antitumor effects of dammarane-type saponins from steamed Notoginseng

He, Fan,Ding, Yan,Liang, Chun,Song, Seok Bean,Dou, De-Qiang,Song, Gyu Yong,Kim, Young Ho Medknow PublicationsMedia Pvt Ltd 2014 Pharmacognosy magazine Vol.10 No.39

<P>Six dammarane-type saponins were extracted from steamed <I>Panax notoginseng</I>. Their chemical structures were identified spectroscopically as ginsenosides Rh<SUB>1</SUB> (1), Rg<SUB>1</SUB> (2), 20 (S)-Rg<SUB>3</SUB> (3), 20 (R)-Rg<SUB>3</SUB> (4), Rb<SUB>3</SUB> (5), and Rb<SUB>1</SUB> (6). Compounds (0.1-10 μM) were tested for inhibition of tumor necrosis factor-α (TNF)-induced nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) luciferase reporter activity using a human kidney 293T cell-based assay. Ginsenoside Rb<SUB>3</SUB> (5) showed the most significant activity with an IC<SUB>50</SUB> of 8.2 μM. This compound also inhibited the induction of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) messenger Ribonucleic acid (mRNA) in a dose-dependent manner after HepG2 cells had been treated with TNF-α (10 ng/mL).</P>