Regenerative capacity of augmented bone in rat calvarial guided bone augmentation model

Kubota, Tatsuya,Hasuike, Akira,Ozawa, Yasumasa,Yamamoto, Takanobu,Tsunori, Katsuyoshi,Yamada, Yutaka,Sato, Shuichi Korean Academy of Periodontology 2017 Journal of Periodontal & Implant Science Vol.47 No.2

Purpose: Guided bone regeneration (GBR) is the most widely used technique to regenerate and augment bones. Even though augmented bones (ABs) have been examined histologically in many studies, few studies have been conducted to examine the biological potential of these bones and the healing dynamics following their use. Moreover, whether the bone obtained from the GBR procedure possesses the same functions as the existing autogenous bone is uncertain. In particular, little attention has been paid to the regenerative ability of GBR bone. Therefore, the present study histologically evaluated the regenerative capacity of AB in the occlusive space of a rat guided bone augmentation (GBA) model. Methods: The calvaria of 30 rats were exposed, and plastic caps were placed on the right of the calvaria in 10 of the 30 rats. After a 12-week healing phase, critical-sized calvarial bone defects (diameter: 5.0 mm) were trephined into the dorsal parietal bone on the left of the calvaria. Bone particles were harvested from the AB or the cortical bone (CB) using a bone scraper and transplanted into the critical defects. Results: The newly generated bone at the defects' edge was evaluated using micro-computed tomography (micro-CT) and histological sections. In the micro-CT analysis, the radiopacity in both the augmented and the CB groups remained high throughout the observational period. In the histological analysis, the closure rate of the CB was significantly higher than in the AB group. The numbers of cells positive for runt-related transcription factor 2 (Runx2) and tartrate-resistant acid phosphatase (TRAP) in the AB group were larger than in the CB group. Conclusions: The regenerative capacity of AB in the occlusive space of the rat GBA model was confirmed. Within the limitations of this study, the regenerative ability of the AB particulate transplant was inferior to that of the CB particulate transplant.

Regenerative capacity of augmented bone in rat calvarial guided bone augmentation model

Tatsuya Kubota,Akira Hasuike,Yasumasa Ozawa,Takanobu Yamamoto,Katsuyoshi Tsunori,Yutaka Yamada,Shuichi Sato 대한치주과학회 2017 Journal of Periodontal & Implant Science Vol.47 No.2

Purpose: Guided bone regeneration (GBR) is the most widely used technique to regenerate and augment bones. Even though augmented bones (ABs) have been examined histologically in many studies, few studies have been conducted to examine the biological potential of these bones and the healing dynamics following their use. Moreover, whether the bone obtained from the GBR procedure possesses the same functions as the existing autogenous bone is uncertain. In particular, little attention has been paid to the regenerative ability of GBR bone. Therefore, the present study histologically evaluated the regenerative capacity of AB in the occlusive space of a rat guided bone augmentation (GBA) model. Methods: The calvaria of 30 rats were exposed, and plastic caps were placed on the right of the calvaria in 10 of the 30 rats. After a 12-week healing phase, critical-sized calvarial bone defects (diameter: 5.0 mm) were trephined into the dorsal parietal bone on the left of the calvaria. Bone particles were harvested from the AB or the cortical bone (CB) using a bone scraper and transplanted into the critical defects. Results: The newly generated bone at the defects' edge was evaluated using micro-computed tomography (micro-CT) and histological sections. In the micro-CT analysis, the radiopacity in both the augmented and the CB groups remained high throughout the observational period. In the histological analysis, the closure rate of the CB was significantly higher than in the AB group. The numbers of cells positive for runt-related transcription factor 2 (Runx2) and tartrate-resistant acid phosphatase (TRAP) in the AB group were larger than in the CB group. Conclusions: The regenerative capacity of AB in the occlusive space of the rat GBA model was confirmed. Within the limitations of this study, the regenerative ability of the AB particulate transplant was inferior to that of the CB particulate transplant.

읍지를 통해서 본 조선시대 평양의 학교와 그 운영

박종배(Park, Jong Bae),蓮池重代(Shigeyo Hasuike) 교육사학회 2017 교육사학연구 Vol.27 No.1

본 논문에서는 16세기 말에서 20세기 초에 걸쳐 연속적으로 편찬된 모두 네 종의 사찬(私撰) 평양지(平壤誌)를 중심으로 조선시대 평양의 학교와 그 운영에 대해 살펴보았다. 본 논문에서 고찰한 바에 따르면, 1507년 평양향교에는 도(道) 단위 양사(養士) 기구인 장도회(長都會)가 설치되었으며, 1576년에는 평양을 대표하는 서원인 인현서원(仁賢書院)이 창건되었고, 이밖에도 평양 지역에는 많은 서원과 사우(祠宇), 재(齋)가 존재하였다. 그리고 평양 지역의 학교에는 「장도회규(長都會規)」와 「학규(學規)」처럼, 학교의 교육과 운영에 관한 자세한 규정이 마련되어 있었다. 아울러 쌀과 면포(綿布), 학전(學田) 등 학교의 경제적 기반 확충을 위한 노력도 계속되었고, 작성고(作成庫)·섬학고(贍學庫) 등 학교에 대한 재정 지원을 전담하는 기구도 운영되었다. 1869년과 1871년에 걸쳐 9개의 원사(院祠)가 철폐된 이후에도 평양 지역에는 홍범당(洪範堂)·구삼원(九三院) 등 10개의 학교가 남아 있었고, 정일재(精一齋, 1877년)와 석송재(石松齋, 1877년), 삼희재(三希齋, 1886년) 등 새로운 학교도 생겨났다. 평양 지역에 존재했던 여러 학교들은 이름만 학교가 아니라, 실제 강학 활동이 이루어진 명실상부한 학교들이었다. 평양지의 편찬자들이 직접 밝혔듯이, 이들을 특별히 읍지의 ‘학교’ 조항에 열거한 것은 ‘모두 거접(居接)하며 장수(藏修)하는 유생들이 있었기 때문’이었다. This study investigated the existence and its management of schools of Pyongyang in Chosun period, focused on 4 kinds of Pyongyangji(平壤誌, the town chronicle of Pyongyang) consecutively published by private writers from the end of the 16<SUP>th</SUP> century to the beginning of the 20<SUP>th</SUP> century. According to this study, Jangdohoe(長都會), a provincial education program in Pyongyang Hyanggyo(鄕校), and Inhyun-Seowon(仁賢書院), the representative Seowon in Pyongyang were established in 1507 and 1576, besides many kinds of Seowon(書院), Sawoo(祠宇), Jae(齋) were managed in Pyongyang. The schools also established the detailed regulations for education and school management in ‘Jangdohoe Regulation’ and ‘Seowon Regulation’. The effort for economic expansion of schools on the rice, cotton stuff and hakjeon(學田) was continued, also Chakseongo(作成庫) and Seomhakgyo(贍學庫) which were exclusively responsible for financial support for schools were administrated. After 9 kinds of Wonsa(院祠) were abolished from 1869 to 1871, 10 schools such as Hongbeomdang(洪範堂) and Gusamwon(九三院) still remained and also many schools such as Jeongiljae(精一齋) and Samhuijae(三希齋) were newly built. As befits its name, many schools in Pyongyang held seminar in practice. As the writers made clear, the schools were mentioned especially in ‘School’ article of Pyongyangji because ‘there are many students of Confucianism who stay in the schools and study for self-cultivation’.

푸코의 에피스테메(episteme) 구분에 따른 코메니우스『세계도회』의 유형 분석

김빛나 ( Binna Kim ),하스이케 시게요 ( Hasuike Shigeyo ),조상식 ( Sang Sik Cho ) 한국교육철학학회 2016 교육철학연구 Vol.38 No.2

푸코는 『말과 사물』에서 에피스테메(episteme)를 특정한 시대의 학문분야나 지식을 대상으로 추출되는 ‘담론의 질서’ 또는 사상사의 ‘선험적 여건’이라고 규정하였다. 에피스테메는 특정한 방식으로 사물들에 질서를 부여하는 ‘무의식적인 기초’라는 점에서 불연속적인 것으로 특징지어진다. 이에 근거하여 푸코는 유럽의 정신사적 시대를 르네상스, 고전주의, 근대라는 단절된 층으로 구분한다. 논문은 이러한 에피스테메의 구분에 의거하여 교육학의 고전인 코메니우스의『세계도회』의 유형이 두 가지 방식으로 분석 가능함을 탐색하고 있다. 하나는 이 교육학 고전이 전형적인 고전주의적 에피스테메인 재현의 방식에 따라 기술되고 있다는 해석이고, 다른 하나는 르네상스로부터 고전주의로 넘어가는 과도기의 성격을 지니고 있다는 해석이다. 재현이라는 고전주의 에피스테메를 반영하고 있다는 근거는 사물들을 재현한 150개 범주의 서술방식이 말과 사물의 일치를 의도했다는 점이다. 반면에 코메니우스의 범지론적 우주상이 언어와 사물의 유비적인 대응관계에 기초한 세계질서를 보여주고 있지만, 동시에 사물과 유리된 언어와 같은 기호로의 전환을 드러내는 재현의 에피스테메를 반영하고 있다는 해석도 가능하다. 논문에서는 이러한 과도기적 유형화 가능성을 논하면서 일본 교육학자들의 주장을 검토하였다. In his book The Order of Things (Les Mots et les choses)(1966) M. Foucault defined ‘episteme’ as a ‘transcendental condition’ of thought history or as an ‘order of discourse`` whose object extracts the disciplinary domain or knowledge in the certain epoch. The episteme has a discontinuous characteristic as far as it is a ‘unconscious fundament`` which gives world of things an order in a particular way. On a basis of such a definition Foucault assorts the periods of European thought history as Renaissance, classical, and modern. This article tries to analyze Comenius`` Orbis Sensualium Pictus(1631) on the basis of episteme typology of Foucault. There can be two possibilities of its analysis: One is an interpretative mode that the Comenius`` book would reflect the one of representation as the typical episteme in the classical epoch, and the other interpretation shows that his work would have the transitional characteristic from the Renaissance into the classical. The ground for the representation episteme in the classical epoch lies in the fact that the description method of 150 categories represented through things would intend to correspond between words and things. On the other hand the stereotyping as the transitional episteme is grounded upon the fact that the cosmological picture consisting of Comenius`` pansophism shows the world order based upon the analogous correspondent relationship between language and things, as well as moves into the space of representation, in which the transition into the symbol such as language detached from things comes out. Especially in order to discuss the possibility of transitional stereotyping, this paper examined the several advanced researches from Japanese community of pedagogy.

일제 강점기 공민과 도입시기 전후 조선의 `공민교육(公民敎育)` 의미 변용에 관한 개념사 연구

임광국 ( Yim Gwang Guk ),김빛나 ( Kim Binna ),하스이케시게요 ( Hasuike Shigeyo ) 한국교육철학학회(구 교육철학회) 2017 교육철학연구 Vol.39 No.3

본 연구는 메이지 유신 이후 성립된 일본의 `공민교육`이 식민지 조선으로 이식되는 과정에서 발생한 개념적 의미 변용과 식민지 조선으로 이식된 공민교육 개념이 시대적·정치적 변화에 따라 어떠한 양상을 보이는지에 대하여 라인하르트 코젤렉의 개념사 연구방법론과 롤프 라이하르트의 의미장을 활용한 개념사 연구이다. 근·현대한국의 공민교육은 일제 강점기에 이식된 근대적 공민교육을 시작으로 하여 현재의 시민교육으로 이어진다. 공민교육의 규범적 의미는 국민주권론에 기반 한 민주적 공민 양성에 있지만, 실제적으로는 국가의 정치적·사회적 이념에 합당한 국민을 구현해 내는 것에 더욱 비중을 둔다. 이렇듯 공민교육은 시대적 환경에서 추구했던 사회적 가치를 반영하기 때문에 시대와 장소에 따라 개념적 함의가 다를 수밖에 없고, 한국의 공민교육 역시 근·현대 사회의 정치사적 변천을 반영하여 시대와 장소에 따른 유의미한 의미 변용을 보인다. 특히 다이쇼데모크라시의 영향을 받은 일본 본토의 공민교육은 자유주의적 공민의 의미가 상당부분 수용되어 있던 반면에 식민지 조선으로 이식된 공민교육은 식민지 정책의 의도가 고스란히 반영된 사실을 확인할 수 있다. 그러나 이러한 와중에서도 공민의 이상적 의미를 토대로 공민교육의 미래적 의미를 자생적으로 선취하여 개념의 `시간화` 양상을 보인다는 점, 그리고 자생적으로 구성된 공민교육의 의미들이 제도권 공민교육과 일정한 대립을 유지하며 개념의 `이념화` 양상을 보인다는 점에서 식민지 조선의 내부에서는 식민지 통치의 의도와는 다른 반의적 의미의 공민교육이 국민주권의 이상적 개념을 토대로 이루어졌다는 점에 주목할 필요가 있다. This is conceptual history research on the transformation of the meanings of the concept of `civic education` as `Japanese civic education` established after the Meiji Restoration was transplanted to the colonial Joseon dynasty, and on the changes of the concept of civic education in the political conditions of Joeson dynasty. For this, the research methodology of Reinhart Koselleck and the semantic field of Rolf Lehrhart are used. Current civic education of Korea began with the modern education that was transplanted in the Japanese colonial period. The normative meaning of civic education lies in the development of democratic citizens based on the doctrine of the national sovereignty, but in reality it places greater emphasis on cultivating the citizens loyal to the political and social ideology of the nation. In this way, the civic education reflects the social values pursued in the varying political environments, and the civic education of Korea also has seen the significant modification of its meanings with the political conditions of the modern society. Especially, the education of citizens in the mainland of Japan, which was affected by the Taisho Democracy, largely accepted the notion of libertarian citizens, while civic education transplanted to the colonial Joseon dynasty reflected the colonial policy. However, attention should be paid to the fact that in the civic education of the colonial Joseon was found the ideal concept of national sovereignty, unlike the intention of the colonial rule. The concept of civic education of the time had both the aspect of `time-shaping` by way of autonomously anticipating the future meaning of civic education on the basis of the ideal meaning of citizens, and the aspect of `idealization` that autonomously structured civic education stood in conflict with the institutional civic education.

Polyp Detection, Characterization, and Management Using Narrow-Band Imaging with/without Magnification

Takahiro Utsumi,Mineo Iwatate,Wataru Sano,Hironori Sunakawa,Santa Hattori,Noriaki Hasuike,Yasushi Sano 대한소화기내시경학회 2015 Clinical Endoscopy Vol.48 No.6

Narrow-band imaging (NBI) is a new imaging technology that was developed in 2006 and has since spread worldwide. Because of its convenience, NBI has been replacing the role of chromoendoscopy. Here we review the efficacy of NBI with/without magnification for detection, characterization, and management of colorectal polyps, and future perspectives for the technology, including education. Recent studies have shown that the next-generation NBI system can detect significantly more colonic polyps than white light imaging, suggesting that NBI may become the modality of choice from the beginning of screening. The capillary pattern revealed by NBI, and the NBI International Colorectal Endoscopic classification are helpful for prediction of histology and for estimating the depth of invasion of colorectal cancer. However, NBI with magnifying colonoscopy is not superior to magnifying chromoendoscopy for estimation of invasion depth. Currently, therefore, chromoendoscopy should also be performed additionally if deep submucosal invasive cancer is suspected. If endoscopists become able to accurately estimate colorectal polyp pathology using NBI, this will allow adenomatous polyps to be resected and discarded; thus, reducing both the risk of polypectomy and costs. In order to achieve this goal, a suitable system for education and training in in vivo diagnostics will be necessary.