Oral Cancer Awareness and Perception of Tobacco Use Cessation Counseling among Dental Students in Four Asian Countries

Halawany, Hassan Suliman,Jacob, Vimal,Abraham, Nimmi Biju,Al-Maflehi, Nassr Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.6

Background: The scientific evidence relating to the burden of oral diseases attributable to tobacco use has been reviewed and the need for a well-structured dental teaching program concentrating on oral cancer education and tobacco cessation interventions has been emphasized. The aim of our study was to evaluate the awareness of oral cancer and perception of tobacco use cessation counseling among dental students at all study levels in India, Saudi Arabia, the United Arab Emirates, and Yemen. Materials and Methods: A structured, pre-tested, self-administered 15-item questionnaire was used to conduct a cross-sectional survey. Data analyses including percentages, frequency distributions and tests of chi-square were generated. Results: A total of 621 (97.6%) Indian, 493 (96.5%) Saudi, 194 (96.5%) Yemeni and 187 (98.4%) United Arab Emirates respondents recognized the association between oral cancer and cigarette smoking. Although more than 96% of the students surveyed recognized the association between oral cancer and cigarette smoking and about 55% reported cigarette smoking as one of the etiological factors of oral cancer, more than 66% of students who reported cigarette smoking as an etiological factor of oral cancer disagreed/strongly disagreed with all the statements concerning tobacco use cessation. Conclusions: A higher level of oral cancer awareness did not have a positive impact on the perception of tobacco use cessation counseling among the sample surveyed.

Comparative Study of Volatile Oil Content and Antimicrobial Activity of Pecan Cultivars Growing in Egypt

Seham S. El Hawary,Soumaya S. Zaghloul,Ali M. El-Halawany,Mahitab H. El Bishbishy 한국식품영양과학회 2013 Journal of medicinal food Vol.16 No.11

The volatile oils obtained from the leaves of four pecan cultivars growing in Egypt were evaluated for their chemical composition and antimicrobial activity. The selected cultivars (cv.) were Carya illinoinensis (Wangneh.) K. Koch. cv. Wichita, C. illinoinensis cv. Western Schley, C. illinoinensis cv. Cherokee, and C. illinoinensis cv. Sioux. The gas chromatography-mass spectrometry analyses revealed that the volatile oils from samples of the different cultivars differ in composition and percentage of their components. b-Curcumene was found as the major constituent of the cv.Wichita oil, whereas germacrene D was the major component of cv. Sioux, cv. Cherokee, and cv. Western Schley. The antimicrobial activity was assayed using the Kirby-Bauer Method by measuring the zone of inhibition of growth. All volatile oils displayed an antimicrobial activity against the tested bacterial strains. On the other hand, only the volatile oil of cv. Wichita showed an antifungal effect on Aspergillus flavus. This work has identified candidates of volatile oils for future in vivo studies to develop antibiotic substitutes for the diminution of human and animal pathogenic bacteria. Nevertheless, the variations of the volatile oil components and antimicrobial potencies of the different studied cultivars, necessitate identifying the cultivars used in future studies.

Bioactive Anthraquinones from Endophytic Fungus Aspergillus versicolor Isolated from Red Sea Algae

Usama W. Hawas,Ahmed Atef El-Beih,Ali M. El-Halawany 대한약학회 2012 Archives of Pharmacal Research Vol.35 No.10

The marine fungus Aspergillus versicolor was isolated from the inner tissue of the Red Sea green alga Halimeda opuntia. The fungus was identified by its morphology and 18s rDNA. Cultivation of this fungal strain led to a new metabolite named isorhodoptilometrin-1-methyl ether (1) along with the known compounds emodin (2), 1-methyl emodin (3), evariquinone (4), 7-hydroxyemodin 6,8-methyl ether (5), siderin (6), arugosin C (7), and variculanol (8). The structures were elucidated on the basis of NMR spectroscopic analysis and mass spectrometry. The biological properties of ethyl acetate extract and compounds 1-3 and 6-8 were explored for antimicrobial activity, anti-cancer activity and inhibition of Hepatitis C virus (HCV) protease.

Towards a Proper Evaluation of Al- Hafiz Arabic Collocations Dictionary: A Corpus-based Study

Al-Halawani, Ali,Khadawardi, Hesham,Elaskary, Mohamed 한국외국어대학교(글로벌캠퍼스) 중동연구소 2015 중동연구 Vol.33 No.3

Collocation has become one of the most controversiallinguistic terms of today. As evidence to this, linguists did notagree up till today as to its exact definition, types or patterns. This may explain, to some extent, the scarcity of collocationaldictionaries and their late appearance regardless of the hugenumber of collocations that can be found in general (i.e. noncollocational)lexicons and dictionaries of nearly all languages. Added to this is the difficulty of compiling a collocationaldictionary unless modern technological tools such ascomputers, huge corpora, and text analysis software are used. This is true as the first English collocational dictionaryappeared in 1986, the BBI, while in Arabic, the first one toappear was Hafiz in 2004 which is the main focus of this paper. This is exactly the reason behind our interest in thisdictionary as it is already the first of its kind in Arabic as ismentioned by its author on its front cover. Collocationdictionaries are indispensable tools for the translator, writerand learner of any foreign language. One of the reasons behindthe errors translators make in rendering collocations from onelanguage to another is that they consult general-purposebilingual dictionaries that do not provide the translators withdetailed explanation or examples of collocations. Hence, thesignificance of this paper as it represents an attempt towardsintroducing a modern-technology-based linguisticmethodological and academic criticism for evaluating such agreat effort aiming at elevating it to the best shape it can beand to help it become a model to be emulated in the field ofcompiling specialized as well as non-specialized Arabic/English and English/Arabic dictionaries. As the dictionary’s author has committed – according to Al-Halawani– a number of methodological, editorial andtranslational mistakes; a matter which makes it incumbentupon specialists to look into its content to clarify suchmistakes and attempt to amend them whenever possible.

알-하피즈 아랍어 연어 사전에 관한 적절한 평가: 코퍼스를 기반으로 한 연구

알리알할라와니 ( Ali Al Halawani ),히샴카다와르디 ( Hesham Khadawardi ),모하메드엘아스카리 ( Mohamed Elaskary ) 한국외국어대학교 중동연구소 2015 중동연구 Vol.33 No.3

연어(collocation) 학습은 외국인 학생과 외국어 학습자에게 있어매우 중요하다. 원어민은 배우지 않아도 자연스럽고 능숙하게 연어를 구사할 수 있지만, 외국인 학습자가 원어민 수준으로 외국어 실력을 향상시키기 위해서는 연어를 학습해야만 한다. 서구 언어학자들과 사전편찬자들이 연어에 대해 관심을 갖기 시작한 것은1933 년부터이다. 최초의 영어 연어 사전(the BBI)이 1986 년에 출간된 반면 아랍어 연어 사전은 2004 년에 처음 발간되었다. 이 논문은 최초의 아랍어 연어 사전인 Al-Hafiz 사전에 대해 살펴보고자 한다. 연어 사전은 번역가, 작가 그리고 외국어 학습자에게 없어서는 안될 필수품이다. 연어 번역에 나타나는 오역의 원인 중 하나는 번역가가 연어에 대한 자세한 설명과 예문이없는 일반 이중언어 사전을 참고하기 때문이다. 이 논문은 언어학적 방법론과 학문적 비평을 기반으로 한 현대 기술의 도입으로 아랍어-영어와 영어-아랍어 범용사전뿐만 아니라 특수사전 분야에서도 선도적 역할을 담당하게 하기 위함을 목적으로 한다. 이 점과 관련하여, 이 논문에서는 Al-Hafiz 사전의 장점과 단점에 대해살펴볼 것이다. 본 연구의 목적은 Al-Hafiz 사전에서 발견되는 오류들을 지적하기 보다는 오류의 수정을 통해 아랍어 사전편찬자들이 이런점들을 활용하여 같은 실수를 반복하지 않게 하는 데 있다. 사전편찬자가 사전 편찬에 좀더 심혈을 기울여서, 일반독자들조차쉽게 발견할 수 있는 오류들을 범하지 않았더라면 Al-Hafiz 사전은더 잘 만들어졌을 것이다. 이에 본 논문은 연어 사전을 편찬하는 데있어 코포라(corpora)나 소프트웨어(software) 같은 현대기술의 활용을 제안한다. Collocation has become one of the most controversial linguistic terms of today. As evidence to this, linguists did not agree up till today as to its exact definition, types or patterns. This may explain, to some extent, the scarcity of collocational dictionaries and their late appearance regardless of the huge number of collocations that can be found in general (i.e. noncollocational) lexicons and dictionaries of nearly all languages. Added to this is the difficulty of compiling a collocational dictionary unless modern technological tools such as computers, huge corpora, and text analysis software are used. This is true as the first English collocational dictionary appeared in 1986, the BBI, while in Arabic, the first one to appear was Hafiz in 2004 which is the main focus of this paper. This is exactly the reason behind our interest in this dictionary as it is already the first of its kind in Arabic as is mentioned by its author on its front cover. Collocation dictionaries are indispensable tools for the translator, writer and learner of any foreign language. One of the reasons behind the errors translators make in rendering collocations from one language to another is that they consult general-purpose bilingual dictionaries that do not provide the translators with detailed explanation or examples of collocations. Hence, the significance of this paper as it represents an attempt towards introducing a modern-technology-based linguistic methodological and academic criticism for evaluating such a great effort aiming at elevating it to the best shape it can be and to help it become a model to be emulated in the field of compiling specialized as well as non-specialized Arabic/ English and English/Arabic dictionaries.As the dictionary’s author has committed-according to Al-Halawani-a number of methodological, editorial and translational mistakes; a matter which makes it incumbent upon specialists to look into its content to clarify such mistakes and attempt to amend them whenever possible.

Comparing dusting and fragmenting efficiency using the new SuperPulsed thulium fiber laser versus a 120 W Holmium:YAG laser

Ben H. Chew,구교철,Abdulghafour Halawani,Colin J. Lundeen,Bodo E. Knudsen,Wilson R. Molina 대한비뇨의학회 2023 Investigative and Clinical Urology Vol.64 No.3

Purpose: Holmium:YAG laser lithotripsy requires high amperage power and has an upper limit of frequency and a minimal fiber size. The technology utilizing thulium-doped fiber offers low pulse energy settings and high pulse frequencies up to 2,400 Hz. We compared the novel SuperPulsed thulium fiber laser (SOLTIVE™; Olympus) to a commercially available 120 W Ho:YAG laser. Materials and Methods: Bench-top testing was conducted with 125 mm3 standardized BegoStones (Bego USA). Time to ablate the stone into particles <1 mm was recorded for efficiency calculations. Finite energy was delivered, and resulting particle sizes were measured to determine fragmentation (0.5 kJ) and dusting (2 kJ) efficiencies. Remaining mass or number of fragments were measured to compare efficacy. Results: SOLTIVE™ was faster at ablating stones to particles <1 mm (2.23±0.22 mg/s, 0.6 J 30 Hz short pulse) compared to Ho:YAG laser (1.78±0.44 mg/s, 0.8 J 10 Hz short pulse) (p<0.001). Following 0.5 kJ of energy in fragmentation testing, fewer particles >2 mm remained using SOLTIVE™ than Ho:YAG laser (2.10 vs. 7.20 fragments). After delivering 2 kJ, dusting (1.05±0.08 mg/s) was faster using SOLTIVE™ (0.1 J 200 Hz short pulse) than 120 W 0.46±0.09 mg/s (0.3 J 70 Hz Moses) (p=0.005). SOLTIVE™ (0.1 J 200 Hz) produced more dust particles <0.5 mm (40%) compared to 24% produced by the P120 W laser at 0.3 J 70 Hz Moses and 14% at 0.3 J 70 Hz long pulse (p=0.015). Conclusions: The efficacy of SOLTIVE™ is superior to the 120 W Ho:YAG laser by producing smaller dust particles and fewer fragments. Further studies are warranted.

Brown Tumor of the Cervical Spines: A Case Report with Literature Review

Mohammad Dursi Alfawareh,Mohammed Mohamoud Halawani,Walid Ismail Attia,Mohamoud Halawani 대한척추외과학회 2015 Asian Spine Journal Vol.9 No.1

To report a rare case of axis brown tumor and to review literature of cervical spine brown tumor. Brown tumor is a rare bone lesion, incidence less than 5% in primary hyperparathyroidism. It is more common in secondary hyperparathyroidism with up to 13% of cases. Brown tumor reactive lesion forms as a result of disturbed bone remodeling due to long standing increase in parathyroid hormones. Cervical spine involvement is extremely rare, can be confused with serous spine lesions. To date, only four cases of cervical spine involvement have been reported. Three were due to secondary hyperparathyroidism. Only one was reported to involve the axis and was due to secondary hyperparathyroidism. This is the first reported case of axis brown tumor due to primary hyperparathyroidism. A case report of brown tumor is presented. A literature review was conducted by a Medline search of reported cases of brown tumor, key words: brown tumor, osteoclastoma and cervical lesions. The resulting papers were reviewed and cervical spine cases were listed then classified according to the level, cause, and management. Only four previous cases involved the cervical spine. Three were caused by secondary hyperparathyroidism and one was by primary hyperparathyroidism which involved the C6. Our case was the first case of C2 involvement of primary hyperparathyroidism and it was managed conservatively. Brown tumor, a rare spinal tumor that presents with high PTH and giant cells, requires a high level of suspicion.

Formulation of Ceftriaxone Conjugated Gold Nanoparticles and Their Medical Applications against Extended-Spectrum β-Lactamase Producing Bacteria and Breast Cancer

( Sanaa M. F. Gad El-rab ),( Eman M. Halawani ),( Aziza M. Hassan ) 한국미생물생명공학회(구 한국산업미생물학회) 2018 Journal of microbiology and biotechnology Vol.28 No.9

Gold nanoparticles (AuNP) and their conjugates have been gaining a great deal of recognition in the medical field. Meanwhile, extended-spectrum β-lactamases (ESBL)-producing bacteria are also demonstrating a challenging problem for health care. The aim of this study was the biosynthesis of AuNP using Rosa damascenes petal extract and conjugation of ceftriaxone antibiotic (Cef-AuNP) in inhibiting ESBL-producing bacteria and study of in vitro anticancer activity. Characterization of the synthesized AuNP and Cef-AuNP was studied. ESBLproducing strains, Acinetobacter baumannii ACI1 and Pseudomonas aeruginosa PSE4 were used for testing the efficacy of Cef-AuNP. The cells of MCF-7 breast cancer were treated with previous AuNP and Cef-AuNP at different time intervals. Cytotoxicity effects of apoptosis and its molecular mechanism were evaluated. Ultraviolet-visible spectroscopy and Fourier transform infrared spectroscopy established the formation of AuNP and Cef-AuNP. Transmission electron microscope demonstrated that the formed nanoparticles were of different shapes with sizes of 15~35 nm and conjugation was established by a slight increase in size. Minimum inhibitory concentration (MIC) values of Cef-AuNP against tested strains were obtained as 3.6 and 4 μg/ml, respectively. Cef-AuNP demonstrated a decrease in the MIC of ceftriaxone down to more than 27 folds on the studied strains. The biosynthesized AuNP displayed apoptotic and time-dependent cytotoxic effects in the cells of MCF-7 at a concentration of 0.1 μg/ml medium. The Cef-AuNP have low significant effects on MCF-7 cells. These results enhance the conjugating utility in old unresponsive ceftriaxone with AuNP to restore its efficiency against otherwise resistant bacterial pathogens. Additionally, AuNP may be used as an alternative chemotherapeutic treatment of MCF-7 cancer cells.

Prevalence and Molecular Characterization of Methicillin-Resistant Staphylococcus aureus from Nasal Specimens: Overcoming MRSA with Silver Nanoparticles and Their Applications

Abo-Amer Aly E.,Gad El-Rab Sanaa M. F.,Halawani Eman M.,Niaz Ameen M.,Bamaga Mohammed S. 한국미생물·생명공학회 2022 Journal of microbiology and biotechnology Vol.32 No.12

Staphylococcus aureus is a cause of high mortality in humans and therefore it is necessary to prevent its transmission and reduce infections. Our goals in this research were to investigate the frequency of methicillin-resistant S. aureus (MRSA) in Taif, Saudi Arabia, and assess the relationship between the phenotypic antimicrobial sensitivity patterns and the genes responsible for resistance. In addition, we examined the antimicrobial efficiency and application of silver nanoparticles (AgNPs) against MRSA isolates. Seventy-two nasal swabs were taken from patients; MRSA was cultivated on Mannitol Salt Agar supplemented with methicillin, and 16S rRNA sequencing was conducted in addition to morphological and biochemical identification. Specific resistance genes such as ermAC, aacA-aphD, tetKM, vatABC and mecA were PCR-amplified and resistance plasmids were also investigated. The MRSA incidence was ~49 % among the 72 S. aureus isolates and all MRSA strains were resistant to oxacillin, penicillin, and cefoxitin. However, vancomycin, linezolid, teicoplanin, mupirocin, and rifampicin were effective against 100% of MRSA strains. About 61% of MRSA strains exhibited multidrug resistance and were resistant to 3-12 antimicrobial medications (MDR). Methicillin resistance gene mecA was presented in all MDR-MRSA strains. Most MDR-MRSA contained a plasmid of > 10 kb. To overcome bacterial resistance, AgNPs were applied and displayed high antimicrobial activity and synergistic effect with penicillin. Our findings may help establish programs to control bacterial spread in communities as AgNPs appeared to exert a synergistic effect with penicillin to control bacterial resistance.