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- 저자 : Haining Na (검색결과 5 건)
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Artificial Muscles from Fishing Line and Sewing Thread
Haines, Carter S.,Lima, Má,rcio D.,Li, Na,Spinks, Geoffrey M.,Foroughi, Javad,Madden, John D. W.,Kim, Shi Hyeong,Fang, Shaoli,Jung de Andrade, Mô,nica,Gö,ktepe, Fatma,Gö,ktepe, &Oum American Association for the Advancement of Scienc 2014 Science Vol.343 No.6173
<P><B>Toward an Artificial Muscle</B></P><P>In designing materials for artificial muscles, the goals are to find those that will combine high strokes, high efficiency, long cycle life, low hysteresis, and low cost. Now, <B>Haines <I>et al.</I></B> (p. 868; see the Perspective by <B>Yuan and Poulin</B>) show that this is possible. Twisting high-strength, readily available polymer fibers, such as those used for fishing lines or sewing thread, to the point where they coil up, allowed construction of highly efficient actuators that could be triggered by a number of stimuli.</P>
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Evaluation of Electrospinnability of Celluloses Derived from Different Biomass Resources
Yanhua Chen,Na Teng,Haizhen Chen,Jing Chen,Fei Liu,Haining Na,Jin Zhu 한국섬유공학회 2018 Fibers and polymers Vol.19 No.5
Electrospinnability as well as dissolvability of the celluloses derived from different biomass resources are systematically studied in this work. By analyzing the essentially physical and molecular structure of cellulose in detail, dissolving efficiency and molecular chain entanglement in solution of cellulose are carefully realized. Accordingly, the original factors on electrospinnability of cellulose is revealed. Crystallinity mainly affects the dissolution of cellulose, which is the foundation to achieve electrospinning. Degree of polymerization is the decisive index of cellulose to form molecular entanglement in solution or not. Proper molecular entanglement of cellulose, just as corn cellulose II, could initiate the formation of ultrafine fiber with good morphology in electrospinning. Our research is no doubt helpful to establish a solid scientific and technical foundation for selection of cellulose to achieve high efficiency fabrication of ultrafine fiber in electrospinning.
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Harvesting electrical energy from carbon nanotube yarn twist
Kim, Shi Hyeong,Haines, Carter S.,Li, Na,Kim, Keon Jung,Mun, Tae Jin,Choi, Changsoon,Di, Jiangtao,Oh, Young Jun,Oviedo, Juan Pablo,Bykova, Julia,Fang, Shaoli,Jiang, Nan,Liu, Zunfeng,Wang, Run,Kumar, P American Association for the Advancement of Scienc 2017 Science Vol.357 No.6353
<P>Mechanical energy harvesters are needed for diverse applications, including self-powered wireless sensors, structural and human health monitoring systems, and the extraction of energy from ocean waves. We report carbon nanotube yarn harvesters that electrochemically convert tensile or torsional mechanical energy into electrical energy without requiring an external bias voltage. Stretching coiled yarns generated 250 watts per kilogram of peak electrical power when cycled up to 30 hertz, as well as up to 41.2 joules per kilogram of electrical energy per mechanical cycle, when normalized to harvester yarn weight. These energy harvesters were used in the ocean to harvest wave energy, combined with thermally driven artificial muscles to convert temperature fluctuations to electrical energy, sewn into textiles for use as self-powered respiration sensors, and used to power a light-emitting diode and to charge a storage capacitor.</P>
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Oh, Joonseok,Liu, Haining,Park, Hyun Bong,Ferreira, Daneel,Jeong, Gil-Saeng,Hamann, Mark T.,Doerksen, Robert J.,Na, MinKyun Elsevier 2017 Biochimica et biophysica acta, General subjects Vol.1861 No.1
<P><B>Abstract</B></P> <P><B>Background</B></P> <P>Inhibition of fatty acid synthase (FAS) is regarded as a sensible therapeutic strategy for the development of optimal anti-cancer agents. Flavonoids exhibit potent anti-neoplastic properties.</P> <P><B>Methods</B></P> <P>The MeOH extract of <I>Sophora flavescens</I> was subjected to chromatographic analyses such as VLC and HPLC for the purification of active flavonoids. The DP4 chemical-shift analysis protocol was employed to investigate the elusive chirality of the lavandulyl moiety of the purified polyphenols. Induced Fit docking protocols and per-residue analyses were utilized to scrutinize structural prerequisites for hampering FAS activity. The FAS-inhibitory activity of the purified flavonoids was assessed via the incorporation of [<SUP>3</SUP>H] acetyl-CoA into palmitate.</P> <P><B>Results</B></P> <P>Six flavonoids, including lavandulyl flavanones, were purified and evaluated for FAS inhibition. The lavandulyl flavanone sophoraflavanone G (<B>2</B>) exhibited the highest potency (IC<SUB>50</SUB> of 6.7±0.2μM), which was more potent than the positive controls. Extensive molecular docking studies revealed the structural requirements for blocking FAS. Per-residue interaction analysis demonstrated that the lavandulyl functional group in the active flavonoids (<B>1</B>–<B>3</B> and <B>5</B>) significantly contributed to increasing their binding affinity towards the target enzyme.</P> <P><B>Conclusion</B></P> <P>This research suggests a basis for the <I>in silico</I> design of a lavandulyl flavonoid-based architecture showing anti-cancer effects via enhancement of the binding potential to FAS.</P> <P><B>General significance</B></P> <P>FAS inhibition by flavonoids and their derivatives may offer significant potential as an approach to lower the risk of various cancer diseases and related fatalities. <I>In silico</I> technologies with available FAS crystal structures may be of significant use in optimizing preliminary leads.</P> <P><B>Highlights</B></P> <P> <UL> <LI> FAS is a pertinent therapeutic target for the development of cancer agents. </LI> <LI> Lavandulyl flavanones exhibited powerful FAS inhibitory activity. </LI> <LI> The lavandulyl functional group contributed to enhancing their binding affinity. </LI> <LI> <I>In silico</I> design and optimization of flavonoid-based FAS inhibitors may be feasible. </LI> </UL> </P>
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Electrical Power From Nanotube and Graphene Electrochemical Thermal Energy Harvesters
Kang, Tae June,Fang, Shaoli,Kozlov, Mikhail E.,Haines, Carter S.,Li, Na,Kim, Yong Hyup,Chen, Yongsheng,Baughman, Ray H. WILEY‐VCH Verlag 2012 Advanced functional materials Vol.22 No.3
<P><B>Abstract</B></P><P>Nanocarbon‐based thermocells involving aqueous potassium ferro/ferricyanide electrolyte are investigated as an alternative to conventional thermoelectrics for thermal energy harvesting. The dependencies of power output on thermocell parameters, such as cell orientation, electrode size, electrode spacing, electrolyte concentration and temperature, are examined to provide practical design elements and principles. Observation of thermocell discharge behavior provides an understanding of the three primary internal resistances (i.e., activation, ohmic and mass transport overpotentials). The power output from nanocarbon thermocells is found to be mainly limited by the ohmic resistance of the electrolyte and restrictions on mass transport in the porous nanocarbon electrode due to pore tortuosity. Based on these fundamental studies, a comparison of power generation is conducted using various nanocarbon electrodes, including purified single‐walled and multi‐walled carbon nanotubes (P‐SWNTs and P‐MWNTs, respectively), unpurified SWNTs, reduced graphene oxide (RGO) and P‐SWNT/RGO composite. The P‐SWNT thermocell has the highest specific power generation per electrode weight (6.8 W/kg for a temperature difference of 20 °C), which is comparable to that for the P‐MWNT electrode. The RGO thermocell electrode provides a substantially lower specific power generation (3.9 W/kg).</P>
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