http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Hannah Woopen,Klaus Pietzner,Rolf Richter,Christina Fotopoulou,Thomas Joens,Elena Ioana Braicu,Håkan Mellstedt,Sven Mahner,Horst Lindhofer,Silvia Darb-Esfahani,Carsten Denkert,Jalid Sehouli 대한부인종양학회 2014 Journal of Gynecologic Oncology Vol.25 No.3
Objective: Epithelial cell adhesion molecule (EpCAM) has experienced a renaissance lately as a binding site for targeted therapy as well as a prognostic marker in epithelial malignancies. Aim of this study was to study EpCAM as a potential prognostic marker in epithelial ovarian cancer (EOC). Methods: EpCAM expression was assessed by immunohistochemistry on paraffin-embedded primary EOC-tissue samples. EpCAM overexpression was defined as an expression of EpCAM of 76% to 100%. Tissue samples and clinical data were systematically collected within the international and multicenter “Tumorbank Ovarian Cancer” network. Results: Seventy-four patients, diagnosed with EOC between 1994 and 2009, were included in the study (median age, 56 years; range, 31 to 86 years). The majority of the patients (81.1%) presented with an advanced stage International Federation of Gynecology and Obstetrics (FIGO) III/IV disease. Histology was of the serous type in 41 patients (55.4%), endometrioid in 19 (25.6%), and mucinous in 14 (19%). EpCAM was overexpressed in 87.7%. Serous tumors overexpressed EpCAM significantly more often than mucinous tumors (87.8% vs. 78.6%, p=0.045); while no significant difference was noted between the other histological subgroups. EpCAM overexpression was significantly associated with a better progression free survival and higher response rates to platinum based chemotherapy (p=0.040 and p=0.048, respectively). EpCAM was identified as an independent prognostic marker for overall survival (p=0.022). Conclusion: Our data indicate a significant association of EpCAM overexpression with a more favorable survival in EOC-patients. Serous cancers showed a significant EpCAM overexpression compared to mucinous types. Larger multicenter analyses are warranted to confirm these findings.
Microporous Ceramic Membranes - on the Way to Large Scale Application
H. Richter,U. Lubenau,P. Puhlfürß,Ch. Pflieger,M. Weyd,R. Mothes,D. Worch,I. Voigt,A. Michaelis 한국막학회 2017 한국막학회 총회 및 학술발표회 Vol.2017 No.11
High membrane costs hinders large scale application of microporous ceramic membranes. Preparation on elements of large specific membrane area are a prospective strategy to overcome this problem. NF membranes with a cut-off of 450 Da were produced for first time in a 163-channel tube geometry of 1.25 m². The membranes were successful tested in drink water production and in treatment of produced water from oil production. Zeolite-NaA-membranes were prepared for the first time inside of 1.2 m long tubes in four channel geometry of 0.9 m². Natural gas is dried by stripping with triethylene glycol (TEG). TEG will be regenerated by distillation at 190°C to 205°C. A pilot plant for TEG drying with Zeolite-NaAmembranes at 120°C for a capacity of 10.000 m³/h natural gas and is running since October 2016.
Han, K. M.,Song, C. H.,Ahn, H. J.,Park, R. S.,Woo, J. H.,Lee, C. K.,Richter, A.,Burrows, J. P.,Kim, J. Y.,Hong, J. H. Copernicus GmbH 2009 Atmospheric chemistry and physics Vol.9 No.3
<P>Abstract. In this study, NO2 columns from the US EPA Models-3/CMAQ model simulations carried out using the 2001 ACE-ASIA (Asia Pacific Regional Aerosol Characterization Experiment) emission inventory over East Asia were compared with the GOME-derived NO2 columns. There were large discrepancies between the CMAQ-predicted and GOME-derived NO2 columns in the fall and winter seasons. In particular, while the CMAQ-predicted NO2 columns produced larger values than the GOME-derived NO2 columns over South Korea for all four seasons, the CMAQ-predicted NO2 columns produced smaller values than the GOME-derived NO2 columns over North China for all seasons with the exception of summer (summer anomaly). It is believed that there might be some error in the NOx emission estimates as well as uncertainty in the NOx chemical loss rates over North China and South Korea. Regarding the latter, this study further focused on the biogenic VOC (BVOC) emissions that were strongly coupled with NOx chemistry during summer in East Asia. This study also investigated whether the CMAQ-modeled NO2/NOx ratios with the possibly overestimated isoprene emissions were higher than those with reduced isoprene emissions. Although changes in both the NOx chemical loss rates and NO2/NOx ratios from CMAQ-modeling with the different isoprene emissions affected the CMAQ-modeled NO2 levels, the effects were found to be limited, mainly due to the low absolute levels of NO2 in summer. Seasonal variations of the NOx emission fluxes over East Asia were further investigated by a set of sensitivity runs of the CMAQ model. Although the results still exhibited the summer anomaly possibly due to the uncertainties in both NOx-related chemistry in the CMAQ model and the GOME measurements, it is believed that consideration of both the seasonal variations in NOx emissions and the correct BVOC emissions in East Asia are critical. Overall, it is estimated that the NOx emissions are underestimated by ~57.3% in North China and overestimated by ~46.1% in South Korea over an entire year. In order to confirm the uncertainty in NOx emissions, the NOx emissions over South Korea and China were further investigated using the ACE-ASIA, REAS (Regional Emission inventory in ASia), and CAPSS (Clean Air Policy Support System) emission inventories. The comparison between the CMAQ-calculated and GOME-derived NO2 columns indicated that both the ACE-ASIA and REAS inventories have some uncertainty in NOx emissions over North China and South Korea, which can also lead to some errors in modeling the formation of ozone and secondary aerosols in South Korea and North China. </P>
Lee, C.,Richter, A.,Lee, H.,Kim, Y.J.,Burrows, J.P.,Lee, Y.G.,Choi, B.C. Pergamon Press ; Elsevier [distribution] 2008 Atmospheric environment Vol.42 No.7
The East Asian countries have been affected by atmospheric gaseous pollutants (in particular SO<SUB>2</SUB>) transported from the Asian continent as well as Asian dust storms. For investigation of the impact of these anthropogenic trace gases on local air quality in Korea, ground-based measurements using a Multi-Axis Differential Optical Absorption Spectroscopy (MAX-DOAS) system and in situ gas analyzers as well as synoptic meteorological data and scattered sunlight spectra obtained by the satellite-borne instrument, Scanning Imaging Absorption Spectrometer for Atmospheric Chartography (SCIAMACHY) launched on board of Environmental Satellite (ENVISAT) in March 2002, were utilized to retrieve SO<SUB>2</SUB> and trace its transport from the Asian continent to Korea in May 2005. The ground-based measurements were carried out in the region of interest, at Korea Global Watch Observatory (KGAWO) in Korea. Plumes of high SO<SUB>2</SUB> over Chinese industrial areas and their transport to the Korean peninsula were observed in SCIAMACHY data in the period of 21-26 May 2005. Highly increased SO<SUB>2</SUB> was measured by the MAX-DOAS system and in situ gas analyzer in the period of 27-29 May 2005 at KGAWO. These observations are supported by the meteorological results that the air-masses picking up these high SO<SUB>2</SUB> plumes while passing over the Chinese industrial and metropolitan areas were transported to the Korean peninsula. The tropospheric SO<SUB>2</SUB> VCDs over these Chinese industrial and metropolitan areas ranged up to 1.4x10<SUP>17</SUP>molcm<SUP>-2</SUP> in SCIAMACHY data. These SO<SUB>2</SUB> plumes resulted in increased SO<SUB>2</SUB> surface levels of up to 7.8ppbv (measured by an in situ gas analyzer) at KGAWO.
Fine structure of the isoscalar giant quadrupole resonance inSi28andAl27
Usman, I. T.,Buthelezi, Z.,Carter, J.,Cooper, G. R. J.,Fearick, R. W.,Fö,rtsch, S. V.,Fujita, H.,Fujita, Y.,von Neumann-Cosel, P.,Neveling, R.,Papakonstantinou, P.,Pysmenetska, I.,Richter, A.,Roth American Physical Society 2016 Physical Review C Vol.94 No.2
<P>The isoscalar giant quadrupole resonance in Si-28 and Al-27 has been investigated with high-energy-resolution proton inelastic scattering at E-p = 200 MeV and at scattering angles close to the maximum of Delta L = 2 angular distributions with the K600 magnetic spectrometer of iThemba LABS, South Africa. Characteristic scales are extracted from the observed fine structure with a wavelet analysis and compared for Si-28 with random-phase approximation and second random phase approximation calculations with an interaction derived from the Argonne V18 potential by a unitary transformation. A recent extension of the method to deformed nuclei provides the best description of the data, suggesting the significance of Landau damping.</P>