유동화 재순환 반응기에서 석유의 수소첨가 반응시 이탈된 온도제어

이창우,홍영호,함영민 한국산업안전학회 1998 한국안전학회지 Vol.13 No.2

This study was carried out to investigate the effect of on temperature control from actuating method, recycling ratio and the position (top, middle and bottom) of set and controlled temperature within the reactor in adiabatic ebullated recycling condition, when the disturbance was occured. Estimation of the solution were performed numerically using the finite difference method. It was assumed that the reaction is in constant with heat of reaction and the physical properties (density, heat capacity and viscosity, etc) of the reactants are same condition within the reactor.

A Model for Computer-Aided Process Planning System in Flexible Manufacturing Systems

Kang, Young-Sig,Hahm, Hyo-Joon,Rim, Suk-Chul,Kim, Seung-Baum The Korean Society for Quality Management 1994 품질경영학회지 Vol.22 No.1

Most of computer-aided process planning(CAPP) systems have been developed to automate the process planning function. In this paper, we describe an analytical model for a CAPP system in order to improve the performance of production system in flexible manufacturing systems(FMSs) for computer intergrated manufacturing(CIM) architecture. This paper proposes an optimal process planning that minimizes the load time by minimizing the cycle time and the number of workstations using Kang and Hahm's heuristic approach so as to improve the performance of production system under the batch production of discrete products. We also perform simulation using SIMAN language to campare the line utilization of each for various product types. The proposed algorithm can be implemented in existing FMSs for on-line control of product quantity using programmable logic controllers(PLC) and communication devices.

한국과 일본 대학생의 스포츠상황에 대한 도덕적 가치판단수준 비교

함정혜(Chung Hae Hahm) 한국여성체육학회 2013 한국여성체육학회지 Vol.27 No.1

The purpose of this study was to compare the differences of moral reasoning among general students, sports related majors students, and student athletes in Korea and Japan University. We collected total 612 out of 700 (315 from Korea, 297 from Japan) and 88 questionnaires were excluded questionnaire due to incompleteness and unreliable data. For this study, Hahm-Bellar Values Choice Inventory-16(HBVCI-16), which is a Moral Reasoning Questionnaire on Sports Activities, was used. The collected data was analyzed by t-test, one way ANOVA and two way ANOVA with using SPSS Var. 17.0 statistical package program and result were as follow. First, the Japan student`s overall score of moral reasoning were lower compare to Korean university students. Second, there were 1 % higher score of moral reasoning in woman against man and in younger subjects. Sports majored university students presented 1% higher score against other related students and higher grade students presented 5% higher score against lower grade students. Third, among student athletes of Korea and Japan, although there were no significant differences, it was 0.1% higher among those who engaged in individual sports and 5% higher score in those who have less sports career.

Spatial and temporal variation of net community production and its regulating factors in the Amundsen Sea, Antarctica

Hahm, Doshik,Rhee, Tae Siek,Kim, Hae-Cheol,Park, Jisoo,Kim, Young-Nam,Shin, Hyoung Chul,Lee, SangHoon American Geophysical Union 2014 Journal of geophysical research. Oceans Vol.119 No.5

We observed O2/Ar in the surface waters of the Amundsen Sea, Antarctica, during the austral summers in 2011 and 2012 to investigate the variability of net community production (NCP). Corresponding to the typical peak phytoplankton bloom period, the O2/Ar of the Amundsen Sea Polynya (ASP) reached 30% in early January 2011 and had a strong positive correlation with the sea surface temperature (SST) and chlorophyll-a (Chl-a). In contrast, O2/Ar decreased to -10% in the sea ice zone (SIZ), which was likely associated with either net O2 consumption in the unlit area or the entrainment of deep water containing low dissolved oxygen. Near the terminal stage of the phytoplankton bloom in late February 2012, we observed the same contrasting O2/Ar features between the ASP and SIZ. However, the O2/Ar in the ASP was not >10%, which corresponded with the overall reduction in Chl-a, solar radiation, and SST compared with the corresponding values in 2011. The average net community production in the ASP was 119 +/- 79 mmol O2 m-2 d-1 in January 2011, and 23 +/- 14 mmol O2 m-2 d-1 in February 2012. The strong correlations of NCP with SST and mixed layer depth (MLD) indicate that the ASP phytoplankton bloom is likely initiated by a combination of increased light availability and SST in early summer. Low SST and variable fluorescence to maximum florescence ratio (Fv/Fm) in February indicate that decreased solar radiation and Fe availability are likely responsible for the phytoplankton bloom demise.

Chemoprevention of Helicobacter pylori-associated Gastric Carcinogenesis in a Mouse Model : Is It Possible?

Hahm, Ki Baik,Song, Young Joon,Oh, Tae Young,Lee, Jeong Sang,Surh, Young-Joon,Kim Young Bae,Yoo, Byung Moo,Kim, Jin Hong,Han, Sang Uk,Nahm, Ki Taik,Kim, Myung-Wook,Kim, Dae Yong,Cho, Sung Won 한국생화학분자생물학회 2003 BMB Reports Vol.36 No.1

Although debates still exist whether Helicobacter pylory infection is really class I carcinigen or not, H. pylori has been known to provoke precancerous lesions like gastric adenoma and chronic atrophic gastritis with intestinal metaplasia as well as gastric cancer, Chronic persistent, uncontrolled gastric inflammations are possible basis for ensuing gastric carcinogenesis and H. pylori infection increase COX-2 expressions, which might be the one of the mechanisms leading to gastric cancer. To know the implication of long-term treatment of antiinflammatory drugs, rebamipide or nimesulide, on H. pylori-associated gastric carcinogenesis, we infected C57BL/6 mice with H. pylori, expecially after MNU administration to promote carcinogenesis and the effects of the long-term administration of rebamipide or nimesulide were eva,uated. C57BL/6 mice werre sacrificed 50 weeks after H. pylori infection. Colonization rates of H.pylory, degree of gastric inflammation and other pathological changes including atrophic gastitis and metaplasia, serum levels and mRNA transcripts of various mouse cytoknes and chemokines, and NF-κ]B binding activities, and finally the presence of gastric adenocarcinoma were compared between H. pylori infected group (HP), and H.pylori infected group administrated with long-term rebamipide containing pellet diets (HPR) or nimesulide mixed pellets (HPN). Gastric mucosal expressions of ICAM-1, HCAM, MMP, and transcriptional regulations of Nf-κB binding were all significantly decreased in HPR group than in HP group. Multi-probe RNase protection assay showed the significantly decreased mRNA levels of apoptosis related genes and various cytokines genes like IFN-r, RANTES, TNF-α, TNFR p75, IL-1β in HPR group. In the experiment designed to provoke gastric cancer through MNU treatment with H.pylori infection, the incidence of gastric carcinoma was not changed between HP and HPR group, but significantly decreased in HPN group, suggesting the chemoprevention of H. pylori-associated gastric carcinogenesis by COX-2 inhibition. Long-term administration of antiinfalmmatory drugs should be considered in the treatment of H. pylori since they showed the molecular and biologic advantages with possible chemopreventive effect against H. pylori-associated gastric carcinogenesis. If the final concrete proof showing the causal relationship between H. pylori infection and gastric carcinogenesis. If the final concrete proof showing the causal relationship between H. pylori infection and gastric carcinogenesis could be obtained, that will shed new light on chemoprevention of gastirc cancer, that is, that gastric cancer could be prevented through either the eradication of H. pylori or lessening the inflammation provoked by H. pylori infection in high risk group.

DEGREE OF APPROXIMATION BY PERIODIC NEURAL NETWORKS

Hahm, Nahmwoo,Hong, Bum Il The Kangwon-Kyungki Mathematical Society 2014 한국수학논문집 Vol.22 No.2

We investigate an approximation order of a continuous $2{\pi}$-periodic function by periodic neural networks. By using the De La Vall$\acute{e}$e Poussin sum and the modulus of continuity, we obtain a degree of approximation by periodic neural networks.

In Vitro Formation of Active Carboxypeptidase Y from Pro-Carboxypeptidase Y Inclusion Bodies by Fed-Batch Operation

HAHM, MOON SUN,CHUNG, BONG HYUN 한국미생물 · 생명공학회 2001 Journal of microbiology and biotechnology Vol.11 No.5

The gene encoding yeast pro-carboxypeptidase Y (pro-CPY) has been cloned and expressed in Escherichia coli. Most of the expressed pro-CPY was accumulated as cytoplasmic insoluble aggregates. In our previous study [3], active CPY was obtained by renaturation of entirely denatured pro-CPY followed by in vitro proteolytic processing with proteinase K along with the activation process. The same refolding process was performed to produce an active CPY from pro-CPY inclusion bodies with renaturation buffers containing proteinase K at different concentrations. The refolding efficiency decreased from 25% to 2% in the renaturation buffers containing proteinase K at concentrations of 60㎍/ml and 0.6㎍/ml, respectively. In an attempt to increase the refolding efficiency with a lesser amount of proteinase K, a novel fed-batch refolding process was developed. In a fed-batch refolding, 99 ml of the renaturation buffer containing pro-CPY was gradually added into I ml of the renaturation buffer containing 60 ㎍/ml of proteinase K to give a final proteinase K concentration of 0.6 ㎍/ml. The fed-batch refolding process resulted in a refolding efficiency of 18%, which corresponded to a 9-fold increase over that (2%) in the batch process.

THE INSTITUTIONAL DEVELOPMENT OF BLUE HOUSE IN THE PARK CHUNG HEE PRESIDENCY

Hahm, Sung Deuk 경남대학교 극동문제연구소 2002 ASIAN PERSPECTIVE Vol.26 No.2

The presidential staff system in Korea is now a well-developed and necessary resource for the occupant of the Office of the President, which has become known as Blue House, and it is difficult to imagine how presidents could have responded to the pressures and demands without such staff assistance. But it is also true that the development of the presidential staff system has become problematic and the size of the staff is only one part of that problem. This article examines the structure of Blue House, focusing on its organizational changes. The modern presidential staff system in Korea evolved greatly during the Park Chung Hee presidency. His era marked the transformation of the presidency from a small, personalized office to a collection of specialized bureaucracies with hundreds of professional staffers.

A Clinicopathologic Study on Nevus Sebaceus

Hahm, Jeong Hee,Cho, Soyun,Whang, Kyu Kwang 대한피부과학회 2001 Annals of Dermatology Vol.13 No.1

Background : Nevus sebaceus of Jadassohn is a complex anomaly involving the epidermis, dermis, apocrine glands and hair follicles, as well as the sebaceous glands, and a variety of benign and malignant tumors and neurologic abnormalities may be associated with it; however, only a few studies on it have been reported in the Korean literature. Objective : The objectives of this study was to document clinical and histopathologic features of nevus sebaceus in Koreans and compare them to those in the previously reported studies. Method : Clinical records and histopathology of 53 cases of nevus sebaceus diagnosed at Ewha Womans University Tongdaemun Hospital during a period of 18 years were reviewed and analyzed. Results : The average incidence rate of nevus sebaceus among new patients was 0.03%. The male-to-female ratio was 1.04 and the average age at visit, 16.5 years. The lesions had been present since birth or had developed before age 10 in 85% of the cases. All lesions were situated on the head, and the most common site was the scalp. Linear lesions (20.8%) were mostly facial lesions. Histopathologically, the incidence of sebaceous and apocrine glandular hyperplasia was most notable in the 13-18 and over-18 age groups. The sebaceous glands showed small punched out defects or $quot;holes$quot; in 24.5%; ectopic apocrine glands were found in 24.5%. Mature hair follicles were absent or greatly reduced in number in 75.5%. Acanthosis nigricanslike pattern of acanthosis and mild papillomatosis were the dominant changes in the epidermis. Hyperplasias and neoplasms were associated in 15.1%, which included 5 cases of primitive follicular induction and 1 trichoblastoma. Conclusiart : In this series, no examples of malignant neoplasms were identified; however, an early total excision before age 13 is recommended since a variable $quot;deficit malformation$quot; of the follicles with hyperplasia of the epidermis and sebaceous glands becomes more prominent after that age.

Characterization of the Nickel Resistance Gene from Legionella pneumophila : Attenuation of Nickel Resistance by ppk(polyphosphate kinase) Disruption in Escherichia coli

Hahm, Dae Hyun,Yeom, Mi Jung,Ko, Whae Min,Lee, Eunjoo H.,Lee, Hye Jung,Shim, In Sop,Kim, Hong Yeoul 한국미생물 · 생명공학회 2002 Journal of microbiology and biotechnology Vol.12 No.1

A 1,989-bp genomic region encoding nickel resistance genes was isolated from Legionella pneumophila, a pathogen for legionellosis. From a sequencing and computer analysis, the region was found to harbor two structural genes, a nreB-like protein gene (1,149 bp) and a nreA-like protein gene (270 bp), in a row. Both genes exhibited a significant degree of similarity to the corresponding genes from Synechocystis sp. PCC6803 (54% amino acid sequence identity) and Achromobacter xylosoxidans 31A (76%). The gene was successfully expressed in E. coli MG1655 and conferred a nickel resistance of up to 5mM in an LB medium and 3 mM in a TMS medium including gluconate as the sole carbon source. E. coli harboring the nickel resistance gene also exhibited a substantial resistance to cobalt, yet no resistance to cadmium or zinc. Since the extracellular concentration of nickel remained constant during the whole period of cultivation, it was confirmed that the nickel resistance was provided by an efflux system like the Ni^2+ permease (nrsD) of Synechocystis sp. strain PCC6803. Since polyphosphate (poly-P) is known as a global regulator for gene expression as well as a potential virulence factor in E. coli, the nickel resistance of a ppk mutant of E. coli MG1655 harboring the nickel resistance gene from L. pneumophila was compared with that of its parental strain. The nickel resistance was significantly attenuated by ppk inactivation, which was more pronounced in an LB medium than in a TMS medium.