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Spinal Angiolipomas : Clinical Characteristics, Surgical Strategies and Prognosis
Xiaolei Zhang,Sheng Dong,Guoqin Wang,Huifang Zhang,James Jin Wang,Guihuai Wang 대한신경외과학회 2022 Journal of Korean neurosurgical society Vol.65 No.1
Objective : Angiolipomas are usually found in the subcutaneous tissue of the trunk and limbs. Spinal angiolipomas (SALs) are uncommon and have rarely been reported. We report a series of nine SALs patients who received surgical treatment in our department. To summarize the clinical characteristics of SALs, propose our surgical strategies, and evaluate the effects of the operation. Methods : This was a retrospective review of nine SALs patients who received surgical treatment from August 2015 to March 2020. Total or subtotal resection was determined by the axial localization (dorsal or ventral) and the extent of intervertebral foramen involvement. The outcomes were assessed based on the modified Japanese Orthopaedic Association (mJOA) scoring system utilized before surgery and at various follow-up points. Results : Among the nine patients, the mean mJOA score before surgery was 6.6±2.3, compared with 10.1±1.1 at the last follow-up time point (33.4±11.8 months). All patients achieved good outcomes, even in cases of subtotal resection. Conclusion : Early surgical resection of SALs is recommended, and the specific procedures should be determined by the axial localization (dorsal or ventral) and the extent of intervertebral foramen involvement. Most of the patients had a good prognosis, even in cases of subtotal resection.
A Defect Detection Algorithm of Denim Fabric Based on Cascading Feature Extraction Architecture
Shuangbao Ma,Renchao Zhang,Yujie Dong,Yuhui Feng,Guoqin Zhang 한국정보처리학회 2023 Journal of information processing systems Vol.19 No.1
Defect detection is one of the key factors in fabric quality control. To improve the speed and accuracy of denimfabric defect detection, this paper proposes a defect detection algorithm based on cascading feature extractionarchitecture. Firstly, this paper extracts these weight parameters of the pre-trained VGG16 model on the largedataset ImageNet and uses its portability to train the defect detection classifier and the defect recognitionclassifier respectively. Secondly, retraining and adjusting partial weight parameters of the convolution layerwere retrained and adjusted from of these two training models on the high-definition fabric defect dataset. Thelast step is merging these two models to get the defect detection algorithm based on cascading architecture. Then there are two comparative experiments between this improved defect detection algorithm and otherfeature extraction methods, such as VGG16, ResNet-50, and Xception. The results of experiments show thatthe defect detection accuracy of this defect detection algorithm can reach 94.3% and the speed is also increasedby 1–3 percentage points.
alAn Intratracheal Challenge Murine Model of Asthma: Can Bronchial Inflammation Affect the Nose?
Jiaxing Xie,Yin Xi,Qingling Zhang,Guoqin Chen,Luo Wei,Kefang Lai,Nanshan Zhong 대한천식알레르기학회 2015 Allergy, Asthma & Immunology Research Vol.7 No.1
Purpose: Extensive data support the influence of the upper airway on lower airway inflammation and pathophysiology in allergic disease. However, few studies have focused on allergic inflammation in the nose after an isolated lower airway allergen challenge, a situation that can exist clinically when human subjects breathe primarily through the mouth, as occurs when nasally congested. This study used a mouse model to investigate whether upper airway inflammation and hyperresponsiveness were induced by an isolated lower airway allergen challenge. Methods: BALB/c mice were sensitized by systemic intraperitoneal injection of ovalbumin/saline and challenged with intratracheal ovalbumin/saline. Inflammation in the nose and lungs was assessed by cytology and histology of nasal tissues and bronchoalveolar lavage fluid (BALF), while nasal airway resistance and response were measured over 3 days post-challenge. Results: Intratracheal application of an allergen in anaesthetized mice resulted in exclusive deposition in the lower airway. Compared to control animals, ovalbumin -sensitized mice after challenge showed bronchial hyperreactivity and increased IL-5 in the serum BALF, as well as eosinophil infiltration in the lungs. However, nasal histology of the ovalbumin-sensitized mice showed no increase in eosinophil infiltration. The nasal lavage fluid revealed no increase in eosinophils or IL-5, and the nasal airway resistance did not increase after challenge either. Conclusions: In a mouse allergy model, exclusive allergen challenge of the lower airway can elicit a pulmonary and systemic allergic response, but does not induce upper airway inflammatory or physiological responses.
Dissolution Kinetics of Thiourea in Triglycol Solution
Li, Hua,Guo, Feng,Hu, Guoqin,Zhao, Lei,Zhang, Yadong Korean Chemical Society 2010 대한화학회지 Vol.54 No.1
이소프로필 멀케푸탄은 중요한 약품 중간체이며 싸이오우레아와 트리글리콜은 이소프로필 멀케푸탄을 합성을 하는데 중요한 화합물이다. 그러므로 트리글리콜 용액에서의 싸이오우레아의 용해는 이소프로필 멀케푸탄의 생산에 중요하다. 트리글리콜용액에서 싸이오우레아의 용해 반응속도론을 조사하고 이소프로필 멀케푸탄을 생산하는 대체 공정을 제시하는것이 본 연구의 목적이다. 트리글리콜용액에서 싸이오우레아의 용해 반응속도론을 조사하기 위하여 용액 농도와 반응 온도를 중점적으로 관찰하였다. 싸이오우레아의 용해속도는 용액농도와 온도가 증가할수록 증가하였다. Isopropyl mercaptan is an important pharmaceutical intermediate and chemical material. And thiourea and triglycol are the main materials for the synthesis of isopropyl mercaptan. Therefore the dissolution of thiourea in triglycol solution is very important for the production of isopropyl mercaptan. The aims of this study are to examine the dissolution kinetics of thiourea in triglycol solution, and to present an alternative process for producing isopropyl mercaptan. In order to investigate the dissolution kinetics of thiourea in triglycol solution, the concentrations of solution and reaction temperature were selected as experimental parameters. It was determined that the dissolution rate of thiourea increased with the increase in solution concentration and temperature. An empirical equation was used in fitting the data. Statistical analysis indicated small errors and the results should be reliable.