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      • SCIESCOPUSKCI등재

        Two-Step Oxidation of Refractory Gold Concentrates with Different Microbial Communities<sup>s</sup>

        ( Guo-hua Wang ),( Jian-ping Xie ),( Shou-peng Li ),( Yu-jie Guo ),( Ying Pan ),( Haiyan Wu ),( Xin-xing Liu ) 한국미생물 · 생명공학회 2016 Journal of microbiology and biotechnology Vol.26 No.11

        Bio-oxidation is an effective technology for treatment of refractory gold concentrates. However, the unsatisfactory oxidation rate and long residence time, which cause a lower cyanide leaching rate and gold recovery, are key factors that restrict the application of traditional bio-oxidation technology. In this study, the oxidation rate of refractory gold concentrates and the adaption of microorganisms were analyzed to evaluate a newly developed two-step pretreatment process, which includes a high temperature chemical oxidation step and a subsequent bio-oxidation step. The oxidation rate and recovery rate of gold were improved significantly after the two-step process. The results showed that the highest oxidation rate of sulfide sulfur could reach to 99.01 % with an extreme thermophile microbial community when the pulp density was 5%. Accordingly, the recovery rate of gold was elevated to 92.51%. Meanwhile, the results revealed that moderate thermophiles performed better than acidophilic mesophiles and extreme thermophiles, whose oxidation rates declined drastically when the pulp density was increased to 10% and 15%. The oxidation rates of sulfide sulfur with moderate thermophiles were 93.94% and 65.73% when the pulp density was increased to 10% and 15%, respectively. All these results indicated that the twostep pretreatment increased the oxidation rate of refractory gold concentrates and is a potential technology to pretreat the refractory sample. Meanwhile, owing to the sensitivity of the microbial community under different pulp density levels, the optimization of microbial community in bio-oxidation is necessary in industry.

      • Comparison of Primary Breast Cancer Size by Mammography and Sonography

        Wang, Jian-Tao,Chang, Li-Ming,Song, Xin,Zhao, Li-Xin,Li, Jun-Tao,Zhang, Wei-Guo,Ji, Ying-Bin,Cai, Li-Na,Di, Wei,Yang, Xin-Yu Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.22

        Purpose: To compare tumor size by mammography and sonography and align with pathological results in primary breast cancer cases. Materials and Methods: We retrospectively reviewed 95 primary breast cancer patients who underwent mammography and sonography from January 2011 to June 2012. The largest tumor diameter was chosen as sizing reference for each imaging modality. The measurements of mammography and sonography were considered concordant if they were within the measurement of pathological results ${\pm}0.5cm$. Pearson's correlation coefficient was calculated for imaging results. Results: The range of the maximum diameter was 0.6cm-10.5cm and mean value was $3.81{\pm}2.04cm$ by pathological results, 0.7cm-12.4 cm and $3.99{\pm}2.19cm$ by mammography, and 0.9cm-11.0cm and $3.63{\pm}2.01cm$ by sonography, respectively. Sonography (R: 0.754), underestimated tumor size, but had a better correlation with pathological tumor size compared to mammography (R: 0.676), which overestimated tumor size. Conclusions: Sonography is superior to mammography in assessment of primary breast cancer.

      • Study of Proportional Guidance Trajectory Based on Guiding Principle

        Wang Xin,Guo Xin,Yao Jun 보안공학연구지원센터 2015 International Journal of Hybrid Information Techno Vol.8 No.9

        In missile guidance systems, classical proportional navigation law has been used most widely. But with the increasing of the maneuverability of the targets, the classical proportional navigation guidance law has been unable to meet the requirements of people on the ballistic parameters. So this paper will further study the algorithm error of guidance law. Based on the previous theoretical results and the working principle of aircraft in the homing guidance system, this paper studies a guidance trajectory guidance principle which based on the ratio, and has carried on the analysis and the simulation theory. And simulation accuracy analysis has been carried on with practical examples. The results show that the method is put forward to effectively reduce the guided ballistic calculation method of error.

      • Prediction Models for Solitary Pulmonary Nodules Based on Curvelet Textural Features and Clinical Parameters

        Wang, Jing-Jing,Wu, Hai-Feng,Sun, Tao,Li, Xia,Wang, Wei,Tao, Li-Xin,Huo, Da,Lv, Ping-Xin,He, Wen,Guo, Xiu-Hua Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.10

        Lung cancer, one of the leading causes of cancer-related deaths, usually appears as solitary pulmonary nodules (SPNs) which are hard to diagnose using the naked eye. In this paper, curvelet-based textural features and clinical parameters are used with three prediction models [a multilevel model, a least absolute shrinkage and selection operator (LASSO) regression method, and a support vector machine (SVM)] to improve the diagnosis of benign and malignant SPNs. Dimensionality reduction of the original curvelet-based textural features was achieved using principal component analysis. In addition, non-conditional logistical regression was used to find clinical predictors among demographic parameters and morphological features. The results showed that, combined with 11 clinical predictors, the accuracy rates using 12 principal components were higher than those using the original curvelet-based textural features. To evaluate the models, 10-fold cross validation and back substitution were applied. The results obtained, respectively, were 0.8549 and 0.9221 for the LASSO method, 0.9443 and 0.9831 for SVM, and 0.8722 and 0.9722 for the multilevel model. All in all, it was found that using curvelet-based textural features after dimensionality reduction and using clinical predictors, the highest accuracy rate was achieved with SVM. The method may be used as an auxiliary tool to differentiate between benign and malignant SPNs in CT images.

      • No Association Between the USP7 Gene Polymorphisms and Colorectal Cancer in the Chinese Han Population

        Li, Xin,Wang, Yang,Li, Xing-Wang,Liu, Bao-Cheng,Zhao, Qing-Zhu,Li, Wei-Dong,Chen, Shi-Qing,Huang, Xiao-Ye,Yang, Feng-Ping,Wang, Quan,Wang, Jin-Fen,Xiao, Yan-Zeng,Xu, Yi-Feng,Feng, Guo-Yin,Peng, Zhi-Ha Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5

        Colorectal cancer (CRC), now the third most common cancer across the world, is known to aggregate in families. USP7 is a very important protein with an important role in regulating the p53 pathway, which is critical for genomic stability and tumor suppression. We here genotyped eight SNPs within the USP7 gene and conducted a case-control study in 312 CRC patients and 270 healthy subjects in the Chinese Han population. No significant associations were found for any single SNP and CRC risk. Our data eliminate USP7 as a potential candidate gene towards for CRC in the Han Chinese population.

      • SCIESCOPUSKCI등재

        Shikonin ameliorates salivary gland damage and inflammation in a mouse model of Sjögren's syndrome by modulating MAPK signaling pathway

        Wenjing Guo,Xin Wang,Chao Sun,Jian Wang,Tao Wang The Korean Society of Pharmacology 2023 The Korean Journal of Physiology & Pharmacology Vol.27 No.4

        Sjögren syndrome (SS) is a systemic inflammatory autoimmune disease that involves exocrine glands. Shikonin is extracted from comfrey, which is conventionally used as an anti-tumor, antibacterial, and antiviral drug in China. However, the application of Shikonin in SS remains unreported. This study aimed to verify the potential functions of Shikonin in SS progression. Firstly, non-obese diabetic mice were used as the SS mouse model, with C57BL/6 mice serving as the healthy control. It was demonstrated that the salivary gland damage and inflammation were aggravated in the SS mouse model. Shikonin improved salivary gland function decline and injury in the SS mouse model. Moreover, Shikonin reduced inflammatory cytokines and immune infiltration in the SS mouse model. Further experiments discovered that Shikonin attenuated the MAPK signaling pathway in the SS mouse model. Lastly, inhibition of the MAPK signaling pathway combined with Shikonin treatment further alleviated the symptoms of SS. In conclusion, Shikonin ameliorated salivary gland damage and inflammation in a mouse model of SS by modulating the MAPK signaling pathway. Our findings indicate that Shikonin may be a useful drug for SS treatment.

      • KCI등재

        Surface structure-dependent hydrophobicity/oleophilicity of pyrite and its influence on coal flotation

        Xin Qi,Xin Li,Yannan Liang,Hainan Wang,Wei Guo,Xingshun Cong,Fakui Lv,Haijun Zhang 한국공업화학회 2020 Journal of Industrial and Engineering Chemistry Vol.87 No.-

        Flotation is an important method to remove the inorganic sulfur from coal. Its effect depends on thedifference in adhesion between coal and pyrite to air bubbles andflotation reagents. In this study, theinterface properties of coal powder/plate and pyrite powder/crystals were investigated using acomprehensive approach combining wetting process, induction time, contact angle, and X-rayphotoelectron spectroscopy. The experimental results show that the spreading and adsorption speedof diethyl phthalate on pyrite crystals and powder is close to that on coal surface in the air. However, theadsorption rate of pyrite to water is much higher than that of coal. In aqueous environment, it is difficultfor diethyl phthalate to spread on pyrite crystals, especially in alkaline solution. The difference ofhydrophobicity between coal and pyrite at air–water interface is smaller than that at oil–water interface. The adhesion of air bubble and reagent droplet on three pyrite facets is also different. The oxidation ofpyrite {100} is faster and greater than that of {210} and {111} facets in alkaline solution, which is beneficialto the coal desulfurization. Thesefindings disclose the hydrophobicity/oleophilicity and structure-reactivity dependence of pyrite in theflotation.

      • KCI등재

        Rational design of porous NiCo2S4 nanotubes for hybrid supercapacitor

        Wang Haiyang,Liang Miaomiao,He Zemin,Guo Zhun,Zhao Yang,Li Kexuan,Song Wenqi,Zhang Yongming,Zhang Xin,Zhao Yuzhen,Miao Zongcheng 한국물리학회 2022 Current Applied Physics Vol.35 No.-

        The nanotube-consisted flower-like NiCo2S4 is successfully fabricated by a novel two-step hydrothermal technique. X-ray diffraction (XRD) identifies the spinel structure, scanning electron microscopy (SEM) and transmission electron microscopy (TEM) imply the flower-like morphology of the synthesized NiCo2S4. The electrochemical behaviors are studied by cyclic voltammetry and galvanostatic charge-discharge measurements. The NiCo2S4 nanotubes demonstrate enhanced pseudocapacitive performance of 429.5 C g− 1 at current density of 0.5 A g− 1 . The NiCo2S4//AC device delivers high energy density of 37.69 Wh kg− 1 , maximum power density of 4000.6 W kg− 1 and satisfied cycle property of 96% capacitance retention after over 7000 cycles. The results show that the NiCo2S4 nanotubes are promising electrode material for high performance supercapacitor applications.

      • SCIESCOPUSKCI등재

        Fix-frequency robust power model predictive control method for three-phase PWM rectifiers under unbalanced grid conditions

        Guo, Xin,Xiao, Min,Gao, Yu-er,Wang, Qingyu,Wan, Yihao The Korean Institute of Power Electronics 2020 JOURNAL OF POWER ELECTRONICS Vol.20 No.5

        Under unbalanced grid conditions, the controller design of a three-phase pulse width modulation (PWM) rectifier is based on an instantaneous power model. By calculating the current references of the converter according to the instantaneous power model, traditional voltage-oriented control (VOC) methods realize the positive-sequence and negative-sequence active and reactive current control of the converter separately using the proportional-integral (PI) controller. However, due to the inner current loop control structure of the traditional VOC method, it is impossible to realize the regulation of all six power components in a common instantaneous power model under an unbalanced grid. Meanwhile, the control performance of the traditional VOC method with a PI controller is degraded under the circuit parameters uncertainty condition. In this paper, a fixed switching frequency robust power model predictive control method (FRP-MPC) is proposed for three-phase PWM rectifiers under the unbalanced grid condition. The proposed control strategy has a number of advantages. An improved instantaneous power model is used for the fixed switching frequency model predictive controller design under the unbalanced grid condition, which has less power variables than the common instantaneous power model. The robustness of the MPC controller is improved by adding a robust item into the predictive model under circuit parameters uncertainty. Simulation and experiment results verify the effectiveness of the proposed control method.

      • SCIESCOPUSKCI등재

        Measurement of the Intestinal Digestibility of Rumen Undegraded Protein Using Different Methods and Correlation Analysis

        Wang, Y.,Zhang, Y.G.,Liu, Xiaolan,Kopparapu, N.K.,Xin, Hangshu,Liu, J.,Guo, Jianhua Asian Australasian Association of Animal Productio 2015 Animal Bioscience Vol.28 No.10

        Four methods were adopted, including the mobile nylon bag (MNB) method, modified three-step in vitro (MTS) method, original three-step in vitro (OTS) method, and acid detergent insoluble nitrogen (ADIN) estimating method, to evaluate the intestinal digestibility of rumen undegradable protein (DRUP) of 10 types of concentrates and 7 types of roughages. After correlation analysis to determine the DRUP values using the MNB, MTS, OTS, and ADIN methods, the study aimed to find out appropriate methods to replace the MNB method due to its disadvantages such as high price, long time period, and use of a duodenal T-fistula. Three dairy cows with a permanent ruminal fistula and duodenal T-fistula were used in a single-factor experimental design. The results showed that the determined DRUP values using the MNB method for soybean meal, cottonseed meal, rapeseed meal, sunflower meal, corn germ meal, corn, rice bran, barley, wheat bran, corn fiber feed, Alfalfa (Zhao dong), Alfalfa (Long mu 801), Alfalfa (Long mu 803), grass (North), Grass (Inner Mongolia), corn silage and corn straw were 98.13%, 87.37%, 88.47%, 82.60%, 75.40%, 93.23%, 69.27%, 91.27%, 72.37%, 79.03%, 66.72%, 68.64%, 73.57%, 50.47%, 51.52%, 54.05%, and 43.84%, respectively. The coefficient of determination ($R^2=0.964$) of the results between the MTS method and the MNB method was higher than that ($R^2=0.942$) between the OTS method and the MNB method. The coefficient of determination of the DRUP values of the concentrates among the in vitro method (including the MTS and OTS methods) and the MNB method was higher than that of the roughage. There was a weak correlation between the determined DRUP values in concentrates obtained from the ADIN method and those from the MNB method, and there was a significant correlation (p<0.01) between the determined DRUP values of the roughage obtained from the MNB method and those obtained from ADIN method. The DRUP values were significantly correlated with the nutritional ingredients of the feeds. The regression equation was DRUP =100.5566+0.4169CP - 0.4344SP - 0.7102NDF - 0.7950EE ($R^2=0.8668$, p<0.01; CP, crude protein; SP, soluble protein; NDF, neutral detergent fiber; EE, ether extract). It was concluded that both the MTS method and the OTS may suitable to replace the MNB method for determining the DRUP values and the former method was more effective. Only the ADIN method could be used to predict the values of the roughages but conventional nutritional ingredients were available for all of the samples' DRUP.

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