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      • KCI등재

        Magnetic Resonance Imaging Features of Adenosis in the Breast

        Masoumeh Gity,Ali Arabkheradmand,Elham Taheri,Madjid Shakiba,Yassaman Khademi,Bijan Bijan,Mohammad Salehi Sadaghiani,Amir Hossein Jalali 한국유방암학회 2015 Journal of breast cancer Vol.18 No.2

        Purpose: Adenosis lesions of the breast, including sclerosing adenosis and adenosis tumors, are a group of benign proliferative disorders that may mimic the features of malignancy on imaging. In this study, we aim to describe the features of breast adenosis lesions with suspicious or borderline findings on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Methods: In our database, we identified 49 pathologically proven breast adenosis lesions for which the final assessment of the breast MRI report was classified as either category 4 (n=45) or category 5 (n=4), according to the Breast Imaging Reporting and Data System (BI-RADS) published by the American College of Radiology (ACR). The lesions had a final diagnosis of either pure adenosis (n=33, 67.3%) or mixed adenosis associated with other benign pathologies (n=16, 32.7%). Results: Of the 49 adenosis lesions detected on DCE-MRI, 32 (65.3%) appeared as enhancing masses, 16 (32.7%) as nonmass enhancements, and one (2.1%) as a tiny enhancing focus. Analysis of the enhancing masses based on the ACR BI-RADS lexicon revealed that among the mass descriptors, the most common features were irregular shape in 12 (37.5%), noncircumscribed margin in 20 (62.5%), heterogeneous internal pattern in 16 (50.0%), rapid initial enhancement in 32 (100.0%), and wash-out delayed enhancement pattern in 21 (65.6%). Of the 16 nonmass enhancing lesions, the most common descriptors included focal distribution in seven (43.8%), segmental distribution in six (37.5%), clumped internal pattern in nine (56.3%), rapid initial enhancement in 16 (100.0%), and wash-out delayed enhancement pattern in eight (50%). Conclusion: Adenosis lesions of the breast may appear suspicious on breast MRI. Awareness of these suspicious- appearing features would be helpful in obviating unnecessary breast biopsies.

      • SCIESCOPUSKCI등재
      • KCI등재

        Ammonium Production During the Nitrogen-Fixing Process by Wild Paenibacillus Strains and Cell-Free Extract Adsorbed on Nano TiO2 Particles

        ( Shokri Dariush ),( Giti Emtiazi ) 한국미생물 · 생명공학회 2010 Journal of microbiology and biotechnology Vol.20 No.8

        During the nitrogen-fixing process, ammonia (NH3) is incorporated into glutamate to yield glutamine and is generally not secreted. However, in this study, NH3- excreting strains of nitrogen-fixing Paenibacillus were isolated from soil. The ammonium production by the Paenibacillus strains was assayed in different experiments (dry biomass, wet biomass, cell-free extract, and cell-free extract adsorbed on nano TiO2 particles) inside an innovative bioreactor containing capsules of N2 and H2. In addition, the effects of different N2 and H2 treatments on the formation of NH3 were assayed. The results showed that the dry biomass of the strains produced the most NH3. The dry biomass of the Paenibacillus strain E produced the most NH3 at 1.50, 0.34, and 0.27 μM NH3/mg biomass/h in the presence of N2+H2, N2, and H2, respectively, indicating that a combined effluent of N2 and H2 was vital for NH3 production. Notwithstanding, a cell-free extract (CFE) adsorbed on nano TiO2 particles produced the most NH3 and preserved the enzyme activities for a longer period of time, where the NH3 production was 2.45 μM/mg CFE/h over 17 h. Therefore, the present study provides a new, simple, and inexpensive method of NH3 production.

      • KCI등재

        Healthy and Unhealthy Dietary Patterns Are Related to Depression: A Case-Control Study

        Maryam Khosravi,Gity Sotoudeh,Reza Majdzadeh,Somayeh Nejati,Samaneh Darabi,Firoozeh Raisi,Ahmad Esmaillzadeh,Maryam Sorayani 대한신경정신의학회 2015 PSYCHIATRY INVESTIGATION Vol.12 No.4

        ObjectiveaaMajor depressive disorder is the leading cause of disability around the world. The relationship between depression and dietary patterns has been reported in a few studies but with controversial results. This study aimed to investigate this relationship in an Iranian population. MethodsaaIn our study, 330 depressed patients (cases) and healthy people (controls) (1:2) were individually matched according to age, sex and area of residence. New cases of depression were recruited from two psychiatric clinics in Tehran. Interviewers went to each patient’s residential area, and invited qualified individuals to participate in the study as controls. Food intake over the past year was collected using a validated semi quantitative food frequency questionnaire. Dietary patterns were determined by the principal components method. Binary logistic regression was used to test the effect of dietary patterns on depression. ResultsaaWe identified two major dietary patterns by using factor analysis: the healthy and unhealthy dietary patterns. We categorized the scores of these patterns to quartiles. After adjusting for non-depression drug use, job, marital status, children number, and body mass index, the relations of depression and quartiles of two dietary patterns are significant (p=0.04 & p=0.01, respectively). Compared with participants in the lowest quartile, those in the highest quartile had significantly lower odds ratio (OR) for depression in healthy dietary pattern, and higher OR for depression in unhealthy dietary pattern. ConclusionaaThis study indicates that healthy and unhealthy dietary patterns may be associated with the risk of depression. The results can be used for developing interventions that aim to promote healthy eating for the prevention of depression.

      • KCI등재

        A systematic review of the role of vitamin D and calcium in premenstrual syndrome

        Fatemeh Abdi,Gity Ozgoli,Fatemeh Sadat Rahnemaie 대한산부인과학회 2019 Obstetrics & Gynecology Science Vol.62 No.2

        Premenstrual syndrome (PMS) is a common disorder that affects millions of women of reproductive age worldwide. In recent years, there has been a focus on finding accessible, acceptable, and cost-effective therapeutic approacheswith minimal side effects to treat the symptoms of PMS. This systematic review aimed to investigate the role ofcalcium and vitamin D in Premenstrual syndrome. The PubMed, EMBASE, Web of Science, Scopus, Science Direct, andGoogle Scholar databases were systematically searched for relevant articles from clinical trial, case-control, and crosssectionalstudies. The Strengthening the Reporting of Observational Studies in Epidemiology checklist was used toassess the quality of the selected papers. A total of 28 eligible high-quality papers were reviewed. Low serum levelsof calcium and vitamin D during the luteal phase of the menstrual cycle were found to cause or exacerbate thesymptoms of PMS. Therefore, the administration of calcium and vitamin D supplements or the use of a diet rich inthese two substances can restore serum levels and eliminate or reduce the symptoms of PMS. Calcium and vitamin Dsupplementation are recommended as an inexpensive, low-risk, acceptable, and accessible approach to eliminate orreduce the symptoms of PMS.

      • Comparison of Crude and Age-Specific Incidence Rates of Breast, Ovary, Endometrium and Cervix Cancers in Iran, 2005

        Arab, Maliheh,Noghabaei, Giti,Kazemi, Seyyedeh Neda Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.6

        Background: Cancer accounts for 12.6% of total deaths in the world (just after heart disease). Materials and Methods: Frequency and age-specific incidence rates of breast and gynecologic cancers in Iran are calculated based on the dataset of the National Cancer Registry of Iran in 2005. Results: Gynecologic and breast cancer accounted for 7.6% and 25.6% of total cancer cases, respectively. Ovarian cancer was the most frequent gynecologic cancer followed by endometrium. Endometrial cancer revealed the highest age specific incidence rate followed by ovary (after 59 years). Conclusions: Regarding disease burden, breast and gynecologic cases account for 33.4% of total cancer patients. The age specific incidence rate is a useful guide in epidemiologic and future plans.

      • KCI등재

        The effect of various veneering techniques on the marginal fit of zirconia copings

        Mahroo Vojdani,Rashin Giti,Masumeh Taghva,Soheil Pardis,Kianoosh Torabi 대한치과보철학회 2015 The Journal of Advanced Prosthodontics Vol.7 No.3

        PURPOSE This study aimed to evaluate the fit of zirconia ceramics before and after veneering, using 3 different veneering processes (layering, press-over, and CAD-on techniques). MATERIALS AND METHODS Thirty standardized zirconia CAD/CAM frameworks were constructed and divided into three groups of 10 each. The first group was veneered using the traditional layering technique. Press-over and CAD-on techniques were used to veneer second and third groups. The marginal gap of specimens was measured before and after veneering process at 18 sites on the master die using a digital microscope. Paired t-test was used to evaluate mean marginal gap changes. One-way ANOVA and post hoc tests were also employed for comparison among 3 groups (α=.05). RESULTS Marginal gap of 3 groups was increased after porcelain veneering. The mean marginal gap values after veneering in the layering group (63.06 µm) was higher than press-over (50.64 µm) and CAD-on (51.50 µm) veneered groups (P<.001). CONCLUSION Three veneering methods altered the marginal fit of zirconia copings. Conventional layering technique increased the marginal gap of zirconia framework more than pressing and CAD-on techniques. All ceramic crowns made through three different veneering methods revealed clinically acceptable marginal fit.

      • SCIESCOPUSKCI등재

        The effect of various veneering techniques on the marginal fit of zirconia copings

        Torabi, Kianoosh,Vojdani, Mahroo,Giti, Rashin,Taghva, Masumeh,Pardis, Soheil The Korean Academy of Prosthodonitics 2015 The Journal of Advanced Prosthodontics Vol.7 No.3

        PURPOSE. This study aimed to evaluate the fit of zirconia ceramics before and after veneering, using 3 different veneering processes (layering, press-over, and CAD-on techniques). MATERIALS AND METHODS. Thirty standardized zirconia CAD/CAM frameworks were constructed and divided into three groups of 10 each. The first group was veneered using the traditional layering technique. Press-over and CAD-on techniques were used to veneer second and third groups. The marginal gap of specimens was measured before and after veneering process at 18 sites on the master die using a digital microscope. Paired t-test was used to evaluate mean marginal gap changes. One-way ANOVA and post hoc tests were also employed for comparison among 3 groups (${\alpha}$=.05). RESULTS. Marginal gap of 3 groups was increased after porcelain veneering. The mean marginal gap values after veneering in the layering group ($63.06{\mu}m$) was higher than press-over ($50.64{\mu}m$) and CAD-on ($51.50{\mu}m$) veneered groups (P<.001). CONCLUSION. Three veneering methods altered the marginal fit of zirconia copings. Conventional layering technique increased the marginal gap of zirconia framework more than pressing and CADon techniques. All ceramic crowns made through three different veneering methods revealed clinically acceptable marginal fit.

      • KCI등재

        Shape-controlled synthesis of zinc nanostructures mediating macromolecules for biomedical applications

        Seyyed Mojtaba Mousavi,Gity Behbudi,Ahmad Gholami,Seyyed Alireza Hashemi,Zohre Mousavi Nejad,Sonia Bahrani,Wei-Hung Chiang,Lai Chin Wei,Navid Omidifar 한국생체재료학회 2022 생체재료학회지 Vol.26 No.1

        Zinc nanostructures (ZnONSs) have attracted much attention due to their morphological, physicochemical, and electrical properties, which were entailed for various biomedical applications such as cancer and diabetes treatment, anti-inflammatory activity, drug delivery. ZnONS play an important role in inducing cellular apoptosis, triggering excess reactive oxygen species (ROS) production, and releasing zinc ions due to their inherent nature and specific shape. Therefore, several new synthetic organometallic method has been developed to prepare ZnO crystalline nanostructures with controlled size and shape. Zinc oxide nanostructures’ crystal size and shape can be controlled by simply changing the physical synthesis condition such as microwave irradiation time, reaction temperature, and TEA concentration at reflux. Physicochemical properties which are determined by the shape and size of ZnO nanostructures, directly affect their biological applications. These nanostructures can decompose the cell membrane and accumulate in the cytoplasm, which leads to apoptosis or cell death. In this study, we reviewed the various synthesis methods which affect the nano shapes of zinc particles, and physicochemical properties of zinc nanostructures that determined the shape of zinc nanomaterials. Also, we mentioned some macromolecules that controlled their physicochemical properties in a green and biological approaches. In addition, we present the recent progress of ZnONSs in the biomedical fields, which will help centralize biomedical fields and assist their future research development.

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