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RISS 인기검색어
- 검색키워드
- 저자 : G. L. Tiwari (검색결과 6 건)
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Tiwari Anshul,Wang Alberta L.,Li Jiang,Lutz Sharon M.,Kho Alvin T,Weiss Scott T,Tantisira Kelan G,McGeachie Michael J. 대한천식알레르기학회 2021 Allergy, Asthma & Immunology Research Vol.13 No.4
Objective MicroRNAs (miRs) are small non-coding RNA molecules of around 18–22 nucleotides that are key regulators of many biologic processes, particularly inflammation. The purpose of this study was to determine the association of circulating miRs from asthmatic children with seasonal variation in allergic inflammation and asthma symptoms. Methods We used available small RNA sequencing on blood serum from 398 children with mild-to-moderate asthma from the Childhood Asthma Management Program. We used seasonal asthma symptom data at the study baseline and allergen affection status from baseline skin prick tests as primary outcomes. We identified differentially expressed (DE) miRs between pairs of seasons using DESeq2. Regression analysis was used to identify associations between allergy status to specific seasonal allergens and DE miRs in 4 seasons and between seasonal asthma symptom data and DE miRs. We performed pathway enrichment analysis for target genes of the DE miRs using DAVID. Results After quality control, 398 samples underwent differential analysis between the 4 seasons. We found 52 unique miRs from a total of 81 DE miRs across seasons. Further investigation of the association between these miRs and sensitization to seasonal allergens using skin prick tests revealed that 26 unique miRs from a total of 38 miRs were significantly associated with a same-season allergen. Comparison between seasonal asthma symptom data revealed that 2 of these 26 miRs also had significant associations with asthma symptoms in the same seasons: miR-328-3p (P < 0.03) and let-7d-3p (P < 0.05). Enrichment analysis showed that the most enriched pathway clusters were Rap1, Ras, and MAPK signaling pathways. Conclusion Our results show seasonal variation in miR-328-3p and let-7d-3p are significantly associated with seasonal asthma symptoms and seasonal allergies. These indicate a potentially protective role for let-7d-3p and a deleterious role for miR-328-3p in asthmatics sensitized to mulberry. Further work will determine whether these miRs are drivers or results of the allergic response.
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Vis, Morgan L.,Tiwari, Sunil,Evans, Joshua R.,Stancheva, Rosalina,Sheath, Robert G.,Kennedy, Bryan,Lee, Janina,Eloranta, Pertti The Korean Society of Phycology 2020 ALGAE Vol.35 No.3
The freshwater red algal genus Sheathia contains species with heterocortication (both bulbous and cylindrical cells covering the main axis) and homocortication (only cylindrical cells). When the genus was proposed, the species with heterocortication were revised, but all specimens with homocortication were assigned to Sheathia arcuata with the caveat that it may represent a species complex. Recent studies have described new species with homocortication and S. arcuata has been rendered paraphyletic. In the current study, new sequences of the rbcL and 5′ region of the cytochrome c oxidase subunit I markers were combined with previously published data to construct a robust phylogeny and circumscribe new species. Four new species, S. abscondita, S. californica, S. plantuloides, and S. transpacifica are proposed. Examination of morphological characters among homocorticate species show no diagnostic characters to distinguish among species, whereas S. plantuloides is only known from sporophytes (chantransia) so it lacks the typical morphological characters derived from the gametophytes for comparison. Although DNA sequence data would be needed to make a positive species identification, geography could be employed to narrow the identification to one or two species. The genus is geographically widespread having been recorded from oceanic islands and five continents, whereas the individual species typically occur on a single continent. With this study, the number of species recognized in Sheathia is raised to 17; seven heterocorticate and 10 homocorticate, making this genus one of the most species rich in the Batrachospermales. As well, the resulting phylogeny provides insights into the evolution of heterocortication in Sheathia.
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Polymorphic stages of the fresh water blue-green alga, Gomphosphaeria aponina
V. K. Dwivedi,Richa Tandon,G. L. Tiwari 한국조류학회I 2010 ALGAE Vol.25 No.3
The natural growth of a population of Gomphosphaeria aponina Kützing (Chroococcales, Cyanoprocaryota) was studied in a cemented freshwater tank in Allahabad, India. This population appeared to be a polymorphic species. Different species of the genus Gomphosphaeria have been segregated based on morphological features of colonies, cells and mucilage. However, these features are not well defined for different species. Our observations revealed many feature variations and, interestingly, certain features that have been described for different Gomphosphaeria species were seen in a single population. In this study, records of such variable morphological features were possible due to the availability of numerous specimens and continuous observations for more than two years. Further, this study revealed two points:(i) more detailed morphological studies are required both from nature as well as in culture to identify critical differences among the species, and (ii) molecular characterization of taxa appears to be necessary for final species settlement.
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Polymorphic stages of the fresh water blue-green alga, Gomphosphaeria aponina
Dwivedi, V.K.,Tandon, Richa,Tiwari, G.L. The Korean Society of Phycology 2010 ALGAE Vol.25 No.3
The natural growth of a population of Gomphosphaeria aponina Kutzing (Chroococcales, Cyanoprocaryota) was studied in a cemented freshwater tank in Allahabad, India. This population appeared to be a polymorphic species. Different species of the genus Gomphosphaeria have been segregated based on morphological features of colonies, cells and mucilage. However, these features are not well defined for different species. Our observations revealed many feature variations and, interestingly, certain features that have been described for different Gomphosphaeria species were seen in a single population. In this study, records of such variable morphological features were possible due to the availability of numerous specimens and continuous observations for more than two years. Further, this study revealed two points: (i) more detailed morphological studies are required both from nature as well as in culture to identify critical differences among the species, and (ii) molecular characterization of taxa appears to be necessary for final species settlement.
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Simulink 이용한 태양전지 MPPT 방법에 따른 출력특성 분석
백승학(S.H. Baek),임지혜(J.H. Im),티와리카필(K.R Tiwari),김대승(D.S. Kim),이강연(K.H. Lee),최연옥(Y.O. Choi),조금배(G.B. Cho),백형래(H.L. Baek) 대한전기학회 2010 대한전기학회 학술대회 논문집 Vol.2010 No.4
Nowadays has problem of energy resource shortage and environmental pollution. We are looking up various solution plans regarding this problem. Solar power is one of the solution to solve the energy shortage problem. But solar power is affected by the weather. So variation weather we can use Maximum Power Point Tracing device for solar PV system. In this paper, we compared Incremental Conductance method to Perturb & Observation(P&O) method about varying insolation. Two method were on the track of Maximum Power Point (MPP) using Matlab-Simulink.
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