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( Yukie Fuse ),( Mariko Higa ),( Naoko Miyashita ),( Asami Fujitani ),( Kaoru Yamashita ),( Takamasa Ichijo ),( Seiichiro Aoe ),( Takahisa Hirose ) 한국임상영양학회 2020 Clinical Nutrition Research Vol.9 No.1
The aim of our study was to investigate whether high β-glucan-containing barley (7.2 g per 100 g) improves postprandial plasma glucose levels and suppresses postprandial insulin levels during a meal tolerance test in type 2 diabetic patients. A meal tolerance test (500 kcal) was conducted using two types of test meals: a test meal with white rice (WR) alone (WR diet) and a test meal with WR mixed with 50% barley (BR diet) as staple food. The side dish was the same in the both meals. The changes in plasma glucose and serum C-peptide immunoreactivity (CPR) levels for 180 minutes after ingestion of the test meals were compared. Ten patients with type 2 diabetes (age 52.5 ± 15.1 years, and 7 males and 3 females) were included in this study. The mean HbA1c level and body mass index were 8.8 ± 1.4%, and 29.7 ± 4.5 kg/m<sup>2</sup>, respectively. Plasma glucose levels after ingestion of the WR diet or BR diet peaked at 60 minutes, which showed no significant differences between the two types of test meals. However, the incremental area under the curve (IAUC) of plasma glucose levels after ingestion of BR diet was significantly lower than that of WR diet. The serum CPR levels at 180 min and their IAUC over 180 minutes after ingestion of BR diet were significantly lower than those of WR diet. Conclusion: Increase in postprandial plasma glucose and insulin levels was suppressed by mixing high-β-glucan barley with WR in type 2 diabetic patients.
Electric Dipolar Susceptibility of the Anderson-Holstein Model
Takahiro Fuse,Takashi Hotta 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.62 No.12
The temperature dependence of the electric dipolar susceptibility ΧP is discussed on the basis ofthe Anderson-Holstein model with the use of a numerical renormalization group (NRG) technique. Note that ΧP is related to the phonon Green’s function D. In order to obtain a correct temperaturedependence for ΧP at low temperatures, we propose a method to evaluate ΧP through the Dysonequation from the charge susceptibility Χc calculated by using the NRG instead of the direct NRGcalculation of D. We find that the irreducible charge susceptibility estimated from Χc agree withthe perturbation calculation, suggesting that our method works well.
( Mariko Higa ),( Yukie Fuse ),( Naoko Miyashita ),( Asami Fujitani ),( Kaoru Yamashita ),( Takamasa Ichijo ),( Seiichiro Aoe ),( Takahisa Hirose ) 한국임상영양학회 2019 Clinical Nutrition Research Vol.8 No.1
The effect of white rice (WR) mixed with high β-glucan-containing barley at 50% on improvement of postprandial blood glucose levels was assessed by meal tolerance test and continuous glucose monitoring (CGM) in 15 healthy subjects with normal glucose tolerance (age 31.6 ± 12.9 years old, 4 males and 11 females). A meal tolerance test (500 kcal) was conducted using 2 types of test meals: a test meal only with WR and a test meal WR mixed 50% barley, and the side dish was the same in both meals. Blood glucose levels of the subjects 180 minutes after ingestion of the test meals were compared. In addition, a CGM device was attached to the subjects for 2 days when the WR or barley as a staple food was provided 3 times a day for consecutive days, and the daily variation of glucose was investigated. The glucose levels 30 minutes after dietary loads and the area under the blood concentration-time curve over 180 minutes were significantly decreased in the barley consumption group. In CGM, 24-hour mean blood glucose and 24-hour standard deviation of blood glucose were also significantly decreased after ingestion of the barley. Postprandial glucose level elevation was suppressed by mixing high-β-glucan barley with WR in subjects with normal glucose tolerance.