Impact of postoperative complications on clinical and economic consequences in pancreatic surgery

Filip ?e?ka,Bohumil Jon,Eva ?ermakova,Zden?k ?ubrt,Alexander Ferko 대한외과학회 2015 Annals of Surgical Treatment and Research Vol.90 No.1

Purpose: Patients who develop complications consume a disproportionately large share of available resources in surgery; therefore the attention of healthcare funders focuses on the economic impact of complications. The main objective of this work was to assess the clinical and economic impact of postoperative complications in pancreatic surgery, and furthermore to assess risk factors for increased costs. Methods: In all, 161 consecutive patients underwent pancreatic resection. The costs of the treatment were determined and analyzed. Results: The overall morbidity rate was 53.4%, and the in-hospital mortality rate was 3.7%. The median of costs for all patients without complication was 3,963 Euro, whereas the median of costs for patients with at least one complication was significantly increased at 10,670 Euro (P < 0.001). In multivariate analysis American Society of Anesthesiologists ≥ 3 (P = 0.006), multivisceral resection (P < 0.001) and any complication (P < 0.001) were independently associated with increased costs. Conclusion: Postoperative complications are associated with an increase in mortality, length of hospital stay, and hospital costs. The treatment costs increase with the severity of the postoperative complications. Those factors that are known to increase the treatment costs in pancreatic resection should be considered when planning patients for surgery.

Poster Session : PS 0316 ; Hematology : A Case of Pancytopenia

( Filipe Filipe ),( Joana Martins ),( Catarina Espirito Santo ),( Ligia Peixoto ),( Ines Vendrell ),( Helena Luna Pais ),( Alba Acabado ),( Paulo Cantiga Duarte ),( Jose Braz Nogueira ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Megaloblastosis represents a wide group of disorders sharing a common pathophysiological pathway, due to defi cient intake or absorption of Vitamin B12 and folic acid. Major causes for this condition include alcoholism, achlorhydria, pernicious anemia or gastrectomy and celiac disease. It leads to abnormal DNA replication, impaired protein synthesis and nuclear maturation. It presents with macrocytosis, hypersegmented neutrophils, and elevated Lactate dehydrogenase (LDH) levels. It is more prevalent in underdeveloped countries and older populations, having similar gender distribution. Authors present the case of a 69-year-old man, with a previous known history of essential thrombocytosis, medicated with hydroxyurea (with irregular adherence to treatment), congestive heart failure and chronic alcoholism. He was admitted at the emergency room (ER) with symptoms of confusion, slurred speech and fatigue for a week. He presented mucosal palor, fever (38. 1ºC), splenomegaly, and a left lateral maleolar ulcer with a purulent exsudate. Blood values revealed pancytopenia (macrocytic anemia Hb 4. 1 g/dL and MCV 123 fi); Leukocytes 1110x106/L; Platelet count 30. 000x106/L), acute renal failure (blood urea nitrogen 97 mg/dL; creatinine 2. 5 mg/ dL) LDH 1545 U/L. He underwent blood transfusions at the ER, without previous iron tests screening. On subsequent evaluation, authors found levels of Vitamin B12 of 172 pg/mL and folate 0. 9 nmol/L. Patient underwent a bone marrow aspiration with bone biopsy, compatible with megaloblastic anemia. An endoscopy was performed, with histological fi ndings suggestive of atrophic gastritis, with no H. pylori bacilli found. Additional tests such as anti-gastric parietal cells antibodies and anti-intrinsic factor antibodies, were negative. The patient was medicated with Vitamin B12 injections and folic acid, with good reticulocitary response. At discharge he presented, blood values of Hb 8. 7 g/dL; Leukocytes 7110x106/L; and platelet count of 862. 000x106/L. This represents a case of severe pancytopenia, enhancing the relevance of megaloblastosis as differential diagnosis for this entity.

Assessing the effect of CO₂ in Li-O₂/CO₂ Batteries with Tetraglyme Electrolyte

( Filipe Marques Mota ),변혜령,김동하 한국공업화학회 2019 한국공업화학회 연구논문 초록집 Vol.2019 No.1

Reflecting the languished research state of Li-O₂, alternative devices operating under CO₂ or O₂/CO₂ with analogously high theoretical energy density have gained recent attraction. Here, we assess the effect of CO₂ within a 5 to 100% range in Li-O₂/CO₂. In the LiTFSI/tetraglyme electrolyte, the reaction mechanism is swiftly shifted toward the formation of Li₂CO₃ even at 5% CO₂. Conspicuous product and intermediate species identification and quantification are presented. Tuning the CO₂ content is shown to offer superior cyclability, deterred byproduct formation with enhanced electrolyte stability, and extended discharge capacity (1.5-fold), correlated with an induced stabilization of metastable CO₄^-/C₂O₆^2- intermediates in tetraglyme. These findings highlight the promise of a shift in the underlying mechanism of Li-air cells upon CO₂ incorporation on conventional O₂-based devices.

Automated identification of the modal parameters of a cable-stayed bridge: Influence of the wind conditions

Filipe Magalhães,Álvaro Cunha 국제구조공학회 2016 Smart Structures and Systems, An International Jou Vol.17 No.3

This paper was written in the context of a benchmark study promoted by The Hong Kong Polytechnic University using data samples collected in an instrumented cable-stayed bridge. The main goal of the benchmark test was to study the identification of the bridge modes of vibration under different wind conditions. In this contribution, the tools developed at ViBest/FEUP for automated data processing of setups collected by dynamic monitoring systems are presented and applied to the data made available in the context of the benchmark study. The applied tools are based on parametric output only modal identification methods combined with clustering algorithms. The obtained results demonstrate that the proposed algorithms succeeded to automatically identify the modes with relevant contribution for the bridge response under different wind conditions.

Redox Mediators in CO₂-assisted Li-O₂ Batteries: Performance Enhancement and Mechanistic Studies

( Filipe Marques Mota ),변혜령,김동하 한국공업화학회 2020 한국공업화학회 연구논문 초록집 Vol.2020 No.-

While replacing O₂ with air reflects a critical step towards the practical application of Li-air batteries, the present CO₂ alters the O₂ chemistry. In the tetraglyme-electrolyte, minor CO₂ reflected a swift shift towards the formation of Li₂CO₃, requiring impracticable recharge potentials (4.5 V). In our recent study, we revealed that a Br₃ ^-/Br₂ redox mediator could successfully suppress the overcharge potential. Hindered overcharges (~0.5 V) driven by electrochemically-generated Br₂ were found to be a function of the LiBr concentration and the insulating Li₂CO₃ structure. Coupled electrochemical and spectroscopic analyses shed light on the involved redox shuttling steps and unveiled the prominent presence of soluble Br₂···Br₃ ^- loosely-bound anionic complexes at progressive states-of-charge.

Microservices Scheduling Model Over Heterogeneous Cloud-Edge Environments As Support for IoT Applications

Filip, Ion-Dorinel,Pop, Florin,Serbanescu, Cristina,Choi, Chang IEEE 2018 IEEE Internet of things journal Vol.5 No.4

<P>Motivated by the high-interest in increasing the utilization of nongeneral purpose devices in reaching computational objectives with a reduced cost, we propose a new model for scheduling microservices over heterogeneous cloud-edge environments. Our model uses a particular mathematical formulation for describing an architecture that includes heterogeneous machines that can handle different microservices. Since any new model asks for an early risk-analysis of the solution, we improved the CloudSim simulation framework to be suitable for an experiment that includes that kind of systems. In this paper, we discuss two examples of real-life utilizations of our proposed scheduling architecture. For an objective appreciation of the first example, we also include some experimental results based on the developed simulation tool. As a result of our interpretation of the experimental results we find out that some very simple scheduling algorithms may outperform some others in given situations that are frequently present in cloud-edge environments when we are using a microservice-oriented approach.</P>

On Space-times with Commutative and Conformal Anti-invariant Pairing of Null Vector Fields

Filip Defever ...et al KYUNGPOOK UNIVERSITY 2000 Kyungpook mathematical journal Vol.40 No.2

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Speaker Dependent Coefficients for Speaker Recognition

Filip Orsag 보안공학연구지원센터 2010 International Journal of Security and Its Applicat Vol.4 No.1

Use of design optimization techniques in solving typical structural engineering related design optimization problems

Filip Fedorik,Jiří Kala,Antti Haapala,Mikko Malaska 국제구조공학회 2015 Structural Engineering and Mechanics, An Int'l Jou Vol.55 No.6

High powered computers and engineering computer systems allow designers to routinely simulate complex physical phenomena. The presented work deals with the analysis of two finite element method optimization techniques (First Order Method-FOM and Subproblem Approximation Method-SAM) implemented in the individual Design Optimization module in the Ansys software to analyze the behavior of real problems. A design optimization is a difficult mathematical process, intended to find the minimum or maximum of an objective function, which is mostly based on iterative procedure. Using optimization techniques in engineering designs requires detailed knowledge of the analyzed problem but also an ability to select the appropriate optimization method. The methods embedded in advanced computer software are based on different optimization techniques and their efficiency is significantly influenced by the specific character of a problem. The efficiency, robustness and accuracy of the methods are studied through strictly convex two-dimensional optimization problem, which is represented by volume minimization of two bars‟ plane frame structure subjected to maximal vertical displacement limit. Advantages and disadvantages of the methods are described and some practical tips provided which could be beneficial in any efficient engineering design by using an optimization method.

Two Messages out of One 2D Matrix Bar Code

( Filip Cvitic ),( Mario Osvin Pavcevic ),( Jesenka Pibernik ) 한국인터넷정보학회 2015 KSII Transactions on Internet and Information Syst Vol.9 No.3

With the proposed principle of two-dimensional matrix bar code design based on masks, the whole surface of a 2D bar code is used for creating graphic patterns. Masks are a method of overlaying certain information with complete preservation of encoded information. In order to ensure suitable mask performance, it is essential to create a set of masks (mask folder) which are similar to each other. This ultimately allows additional error correction on the whole code level which is proven mathematically through an academic example of a QR code with a matrix of size 9 × 9. In order to create a mask folder, this article will investigate parameters based on Weber`s law. With the parameters founded in the research, this principle shows how QR codes, or any other 2D bar code, can be designed to display two different messages. This ultimately enables a better description of a 2D bar code, which will improve users` visual recognition of 2D bar code purpose, and therefore users` greater enjoyment and involvement.