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      • Bio-inspired Micro Pump Model Based on the Movement Pattern of Sperm

        Feifei Liu,Xiaofei Ren,Shoushui Wei,Zhiping Liu 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.11

        Micro pumps play important roles in microfluidic system. Biologically inspired actuation mechanisms have great advantages in the micro pump design. This work aims to develop a numerical model for bio-inspired micro pump based on the specific and genuine movement pattern of the sperm. The model also employs a modified immersed boundary-lattice Boltzmann method. In the model, an elastic film is used to mimic a sperm moving with its head fixed. The fluctuation vibration of the film could then drive the static fluid to move. The modified immersed boundary-lattice Boltzmann method directly introduces the velocity information of the film into the traditional lattice Boltzmann equation, which improve the computational efficiency. Pressure distribution, streamlines and the flow rate curves are used to analyze the flow field dynamic process of the model. The effects of the model parameters (e.g. frequency, kinematic viscosity, amplitude and wavelength) on the stable flow rate are also studied comprehensively.

      • KCI등재

        Lactobacillus rhamnosus CCFM1107 treatment ameliorates alcohol -induced liver injury in a mouse model of chronic alcohol feeding

        Fengwei Tian,Feifei Chi,Gang Wang,Xiaoming Liu,Qiuxiang Zhang,Yongquan Chen,Hao Zhang,Wei Chen 한국미생물학회 2015 The journal of microbiology Vol.53 No.12

        Lactobacillus rhamnosus CCFM1107 was screened for high antioxidative activity from 55 lactobacilli. The present study attempted to explore the protective properties of L. rhamnosus CCFM1107 in alcoholic liver injury. A mouse model was induced by orally feeding alcohol when simultaneously treated with L. rhamnosus CCFM1107, the drug Hu-Gan- Pian (HGP), L. rhamnosus GG (LGG), and L. plantarum CCFM1112 for 3 months. Biochemical analysis was performed for both serum and liver homogenate. Detailed intestinal flora and histological analyses were also carried out. Our results indicated that the administration of L. rhamnosus CCFM1107 significantly inhibited the increase in the levels of serum aminotransferase and endotoxin, as well as the levels of triglyceride (TG) and cholesterol (CHO) in the serum and in the liver. Glutathione (GSH), glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) were elevated while the levels of malondialdehyde (MDA) were decreased. The enteric dysbiosis caused by alcohol was restored by increasing the numbers of both lactobacilli and bifidobacteria and decreasing the numbers of both enterococci and enterobacter. Histological analysis confirmed the protective effect of L. rhamnosus CCFM1107. Compared with the other lactobacilli and to the drug Hu-Gan-Pian, there is a high chance that L. rhamnosus CCFM1107 provides protective effects on alcoholic liver injury by reducing oxidative stress and restoring the intestinal flora.

      • KCI등재

        Improving organic field-effect transistors based on double active layers structure

        Xinan Guo,Feifei Xing,Fei Hong,Jianhua Zhang,Bin Wei,Jun Wang 한국물리학회 2010 Current Applied Physics Vol.10 No.1

        Organic field-effect transistors (OFETs) were fabricated based on double active layers structure. Different substrate temperatures and thermal treatment were adopted to prepare double active layers and optimize film morphology. The grain size of organic films can be effectively controlled by the change in substrate temperature in the process of deposition. An improved device performance was obtained compared with conventional single layer devices. This result is attributed to the introduction of double active layers. We believe that this kind of optimization will simultaneously improve charge injection and transportation of OFETs.

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        AsJAZ1 represses the expression of the sesquiterpene synthase gene based on the JA signaling pathway in Aquilaria sinensis (Lour.) Gilg

        Liao Yongcui,Pan Rongbin,Wei Jianhe,LV Feifei 한국식물생명공학회 2023 Plant biotechnology reports Vol.17 No.1

        Aquilaria sinensis is a species of plant endemic to China, which is typical wound-induced economic plant. It is widely used in the production of perfume, incense and traditional Chinese medicine. A healthy A. sinensis tree cannot produce agarwood. It forms agarwood only when wounded. Sesquiterpenes and phenylethyl chromone derivatives have been demonstrated to be the main active compounds in agarwood, but little is known about jasmonate (JA) signaling that regulates the biosynthesis of agarwood sesquiterpenes. In this work, we firstly cloned the full-length cDNA sequence of a JA signaling suppressor gene (JAZ) from A. sinensis, and then characterized its roles through bioinformatics prediction, tissue expression, wounding-induced expression, subcellular localization, protein interaction and overexpression analysis in Arabidopsis thaliana. The results showed that the full-length cDNA sequence of JAZ gene (termed as AsJAZ1, GenBank accession number: KP677281) is 1507 bp, containing a complete open reading frame (ORF) of 990 bp. The bioinformatics analysis shows that the deduced amino acid residues contain a tify (ZIM) domain, the same as A. thaliana JAZ3 protein. Mechanical wounding and MeJA were found to up-regulate the expression level of the AsJAZ1 gene. The AsJAZ1 could interact with the MYC2 transcription factor in vitro. The MYC2 transcription factor in Arabidopsis thaliana (AtMYC2) was minimally expressed in transgenic plants and had a weak response to MeJA treatment. The AsJAZ1 overexpression in A. thaliana was observed to down-regulate the expression of sesquiterpene synthase genes (TPS21 and TPS11), suggesting that AsJAZ1 might serve as a repressor to regulate the expression of sesquiterpene synthase genes in Aquilaria plants. Taken together, this work may lay a foundation for identifying the JA signaling pathway and exploring the role of JA signaling in agarwood sesquiterpene biosynthesis in A. sinensis trees.

      • KCI등재

        Ultrasonic Synthesis of Au/AgCl Hybrid Cubes and Their Evolution Under Electron Beam Irradiation

        Hongliang Cao,Xiaoli Miao,Mengqin Zhu,Chang Li,Feifei Wei,Xin Chen 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2015 NANO Vol.10 No.6

        The utilization of ultrasound offers a facile tool for the synthesis of Au/AgCl hybrid particles. We have obtained the architectures of Au nanoparticles on AgCl sub-micrometer cubes by simply ultrasonic irradiating their precursors in ethylene glycol (EG). The formation process of Au/AgCl hybrid particles in the reaction solution has been studied based on the optical absorption spectra and the scanning electron microscope (SEM) images of the particles obtained at different ultrasonic irradiation stages. The dynamic changes of Au/AgCl hybrid particles under electron beam irradiation have been investigated in both SEM and in situ liquid cell transmission electron microscope (TEM). Hollow Au/AgCl hybrid particle structures have been obtained under the electron beam irradiation in liquid, with the cuboid contour shape preserved.

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