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        Poly(lactic acid) Nanofibrous Scaffolds Containing Aspirin-loaded Zeolitic Imidazolate Frameworks: Morphology, Drug Release, Hemocompatibility and Shape Memory Studies

        Fatemeh Salahi Chashmi,Mehrdad Khakbiz,Payam Zahedi,Mahboubeh Kabiri 한국섬유공학회 2022 Fibers and polymers Vol.23 No.8

        Using poly(lactic acid) (PLA) as biodegradable and biocompatible material is demanded for vascular scaffoldsespecially a susceptible substitute of permanent metal stents in treatment of coronary heart disease. In this work, PLAnanofibers containing aspirin (Asp) loaded into zeolitic imidazolate framework nanoparticles (ZIF-8@Asp NPs) wereprepared for vascular tissue application. In this line, ZIF-8@Asp NPs were synthesized, and their characterization revealedtheir average NP size and the drug loading efficiency of approximately 180 nm and 76 %. Afterward, ZIF-8@Asp NPs wereloaded into PLA nanofibers and the obtained results showed a uniform morphology with an average nanofibers diameter ofaround 544 nm, Young’s modulus of 1.7 MPa, and the ultimate drug release of 19 % after six days. Besides degradationstudies of the sample, the addition of ZIF-8@Asp NPs to the PLA nanofibers displayed no adverse effect on the shaperecovery properties. Finally, the hemolysis and platelet adhesion confirmed that the surface of the ZIF-8@Asp-loaded PLAnanofibrous samples exhibited appropriate hemocompatibility.

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        Synthesis, morphology control, and application of hollow Al2O3 spheres in the steam methane reforming process

        Maryam Meshksar,Fatemeh Salahi,Fatemeh Zarei-Jelyani,Mohammad Reza Rahimpour,Mohammad Farsi 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.111 No.-

        This research focuses on controlling the morphology and crystalline phase of hollow Al2O3 spheres as asupporting material of Ni-based catalysts for the first time, which is then applied as a catalyst of hightemperaturesteam methane reforming (SMR) process. For this purpose, the effects of hydrothermal time,the concentration of alumina salt, and calcination temperature on the structure of support are investigatedand adjusted and then loaded with 15–25 wt.% Ni contents. The morphology of synthesized hollowalumina samples and 20Ni/H-Al2O3 catalyst before and after reaction are characterized using XRD,FESEM, TEM, H2-TPR, CO2-TPD, EDX, FTIR, N2 adsorption/desorption, and mapping techniques. Thehydrothermal time of 72 h, calcination temperature of 800 C, and alumina salt concentration of1.00 M resulted in the spherical morphology of hollow Al2O3 with 236.26 m2/gr surface area and highcrystallinity. Among different Ni loadings, 20Ni/H-Al2O3 had the highest CH4 conversion of 87.75% andH2 yield of 92.09% at 700 C. This catalyst also depicted stable performance during 12 h SMR reactionat 700 C with low carbon deposited contents.

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