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- 저자 : Dao Vu Phuong Thao (검색결과 2 건)
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Trang Nguyen Thi Kieu,Phuong Thao Dao Vu,Nguyet Nguyen Thi,Dien Nguyen Dac,Van Hoang Nhu,Van Thu Vu,Tran Manh Trung,Pham Hung Vuong,Tam Phuong Dinh 한국물리학회 2024 Current Applied Physics Vol.63 No.-
Gold nanoflowers (AuNF) were synthesized on a glassy carbon electrode via a one-step, eco-friendly protocol in deep eutectic solvent (DES) of choline choloride and urea, called reline, for label-free detection of DNA hybridization. DES is eco-friendly, low-cost, biocompatible, and nontoxic, and it can be used as an electrolyte to synthesize nanomaterials by using the electrochemical method. In this protocol, highly branched and stable AuNFs were obtained without using any surfactants for DNA sensor application. The electrochemical performance of the AuNF-modified electrode was studied by cyclic voltammetry and electrochemical impedance spectroscopy. Under optimal conditions, the AuNF-based DNA biosensor exhibited a sensitivity of 294.9 Ω nM−1cm−2 and 218 μA nM−1cm−2 and a limit of detection (LOD) of 10−9 M. The remarkable sensitivity and low LOD could be attributed to the good conductivity of AuNFs for accelerating electron transfer, resulting in obvious signal amplification. The DNA biosensor showed good reproducibility (RSD <3.65 %) and acceptable stability and selectivity. Its excellent performance in DNA detection suggested that the proposed electrochemical DNA sensor has great application potential in clinical diagnosis.
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Dinh Van Tuan,Dang Thi Thuy Ngan,Dao Vu Phuong Thao,Nguyen Thi Nguyet,Nguyen Thi Thuy,Nguyen Phuong Thuy,Vu Van Thu,Vuong-Pham Hung,Phuong Dinh Tam 한국물리학회 2022 Current Applied Physics Vol.43 No.-
A facile hydrothermal route was used to synthesize silver nanoparticle (AgNP)-decorated microflower molybdenum disulfide (MoS2-MF) for bio-electrochemical platform fabrication to detect nonenzymatic glucose concentration. The morphologies of the materials were studied by scanning electron microscopy, and their structural characteristics were analyzed by X-ray diffractometry and energy-dispersive X-ray spectroscopy. The electrochemical characteristics of the AgNPs/MoS2-MF/PtE biosensor were studied by cyclic voltammetry. The obtained data indicated that the developed nonenzymatic glucose sensor has a large linear response between 1.0 and 15.0 mM, a limit of detection of as low as 1.0 mM, and a sensitivity of 46.5 μA nM-1 cm-2. The biosensor also displayed outstanding selectivity, stability, reproducibility, and repeatability. Additionally, the AgNPs/MoS2-MF/ PtE biosensor was utilized to detect glucose concentration in real sample and showed practical application potential for glucose detection.
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