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      • SCIESCOPUSKCI등재

        Helicobader pylori Infection: Epidemiology, Pathophysiology, and Therapy

        Crespo, Antonio,Suh, Byungse The Pharmaceutical Society of Korea 2001 Archives of Pharmacal Research Vol.24 No.6

        Helicobacter pylori is one of the most commonly encountered human pathogens. It has been shown to be closely associated with peptic ulcer disease (PUD), gastric adenocarcinoma, and the gastric mucosa-associated lymphoid tissue (MALT) that may lead to gastric lymphoma. The current diagnostic methods include histology, microbiological culture, classic serology unease activity detection, polymerase chain reaction (PCR) and stool antigen detection. Its treatment modality options are multiple; however, a triple regimen consisting of a proton pump inhibitor (PPI), and two antibiotics for 10 to 14 days is preferred. Drug resistance is a growing problem in this organism and new therapeutic options are currently limited .

      • SCOPUSKCI등재
      • SCOPUSKCI등재

        Multiple Chemical Sensitivity in Chemical Laboratory Workers

        Perez-Crespo, Juan,Lobato-Canon, Rafael,Solanes-Puchol, Angel Occupational Safety and Health Research Institute 2018 Safety and health at work Vol.9 No.4

        Background: Multiple Chemical Sensitivity (MCS) is an acquired disease which etiology remains unknown. It is characterized by the development of sensitivity to certain chemical products. Most of the hypotheses formulated to explain the syndrome associate it to a previous exposition to some kind of volatile chemical. University researchers in chemical laboratories suffer a phenomenon of multi-exposition to chemical agents at low concentration during long periods of time although in an irregular form. Many of these chemical agents have similar properties to those suspicious of causing MCS. This article studies the prevalence of MCS in laboratory researchers. Methods: The study group is university researchers in chemical laboratories. The control group was obtained from administrative personnel who work in the same universities and therefore, are not exposed to chemical products from the laboratories, but have the same exposition to the rest of environmental polluting agents from the area and from the buildings of the university. In this study, it is used the Quick Environmental Exposure and Sensitivity Inventory (QEESI) (sensitivity of 92%/specificity of 95%). Results: The results showed that the prevalence of MCS for the university researchers is not related to exposition by inhalation to multiple chemical agents, at low concentration. Conclusions: The results disagree with one of the main etiological hypotheses of MCS, which is based on the existence of hypersensitive people, who presents a response after prolonged expositions to very low concentrations during a long period of time.

      • KCI등재

        Multiple Chemical Sensitivity in Chemical Laboratory Workers

        Juan Pérez-Crespo,Rafael Lobato-Cañón,Ángel Solanes-Puchol 한국산업안전보건공단 산업안전보건연구원 2018 Safety and health at work Vol.9 No.4

        Background: Multiple Chemical Sensitivity (MCS) is an acquired disease which etiology remains unknown. It is characterized by the development of sensitivity to certain chemical products. Most of the hypotheses formulated to explain the syndrome associate it to a previous exposition to some kind of volatile chemical. University researchers in chemical laboratories suffer a phenomenon of multiexposition to chemical agents at low concentration during long periods of time although in an irregular form. Many of these chemical agents have similar properties to those suspicious of causing MCS. This article studies the prevalence of MCS in laboratory researchers. Methods: The study group is university researchers in chemical laboratories. The control group was obtained from administrative personnel who work in the same universities and therefore, are not exposed to chemical products from the laboratories, but have the same exposition to the rest of environmental polluting agents from the area and from the buildings of the university. In this study, it is used the Quick Environmental Exposure and Sensitivity Inventory (QEESI) (sensitivity of 92%/specificity of 95%). Results: The results showed that the prevalence of MCS for the university researchers is not related to exposition by inhalation to multiple chemical agents, at low concentration. Conclusions: The results disagree with one of the main etiological hypotheses of MCS, which is based on the existence of hypersensitive people, who presents a response after prolonged expositions to very low concentrations during a long period of time.

      • KCI등재

        Long-Term Grey Matter Changes in First Episode Psychosis: A Systematic Review

        Ruth Gallardo-Ruiz,Benedicto Crespo-Facorro,Esther Setié,n-Suero,Diana Tordesillas-Gutierrez 대한신경정신의학회 2019 PSYCHIATRY INVESTIGATION Vol.16 No.5

        Objective: To determine possible progressive changes of the grey matter at the first stages of the schizophrenia spectrum disorders, and to determine what regions are involved in these changes. Methods: We searched the literature concerning studies on longitudinal changes in grey matter in first-episode psychosis using magnetic resonance imaging, especially studies with an interval between scans of more than a year. Only articles published before 2018 were searched. We selected 19 magnetic resonance imaging longitudinal studies that used different neuroimaging analysis techniques to study changes in cerebral grey matter in a group of patients with a first episode of psychosis. Results: Patients with first episode of psychosis showed a decrease over time in cortical grey matter compared with a group of control subjects in frontal, temporal (specifically in superior regions), parietal, and subcortical regions. In addition to the above, studies indicate that patients showed a grey matter decrease in cerebellum and lateral ventricles volume. Conclusion: The results suggest a decrease in grey matter in the years after the first episode of psychosis. Furthermore, the results of the studies showed consistency, regardless of the methods used in their analyses, as well as the time intervals between image collections.

      • SCIESCOPUSKCI등재

        Reproductive development and seasonal activity of two Korean native Coprini species (Coleoptera: Scarabaeidae)

        Bang, Hea-Son,Crespo, Carmen Huerta,Na, Young-Eun,Han, Min-Su,Lee, Joon-Ho 한국응용곤충학회 2008 Journal of Asia-Pacific Entomology Vol. No.

        Seasonal activity of the native dung beetles, Copris ochus (Motschulsky) and Copris tripartitus Waterhouse, was studied in Jeju Island, Korea. Reproductive condition and breeding cycles of adult females were determined using physiological age-grading techniques to assess the proportions of newly emerged, nulliparous and parous beetles, and those resorbing oocytes. C. ochus appears to be univoltine. Its main period of adult emergence occurs in summer rather than in spring (March-May), as was previously thought. The female population consisted of the complete range of reproductive age classes in August-September. C. tripartitus also appears to be univoltine. However, this species has two adult activity periods: a peak activity in spring when most oviposition occurs, and another in autumn when the new generation emerges. With the onset of winter, C. tripartitus adults cease reproductive development and females over winter in a nulliparous stage.

      • KCI등재후보

        Philosophical Practice and Aporia in Prison

        Maria daVenza Tillmanns,Wilfredo (Willy) Crespo 강원대학교 인문과학연구소 2018 Journal of Humanities Therapy Vol.9 No.2

        In this paper we discuss how through our bi-weekly Socratic dialogue groups with inmates at the Metropolitan Correctional Center downtown San Diego, we were able to bring the inmates to a sense of aporia or puzzlement. Not only did the dialogues help to uncover assumptions, uncovering the dots, so to speak, but also to help reconnect the dots and see their world from a different perspective. It allowed them to question their lives in a safe and non-judgmental environment. They felt empowered by these dialogues to become their own life’s judges, freeing themselves from feeling oppressed by the judgments of others.

      • KCI등재

        Reproductive development and seasonal activity of two Korean native Coprini species (Coleoptera: Scarabaeidae)

        Hea-Son Bang,Carmen Huerta Crespo,Young-Eun Na,Min-Su Han,이준호 한국응용곤충학회 2008 Journal of Asia-Pacific Entomology Vol.11 No.4

        Seasonal activity of the native dung beetles, Copris ochus (Motschulsky) and Copris tripartitus Waterhouse, was studied in Jeju Island, Korea. Reproductive condition and breeding cycles of adult females were determined using physiological age-grading techniques to assess the proportions of newly emerged, nulliparous and parous beetles, and those resorbing oocytes. C. ochus appears to be univoltine. Its main period of adult emergence occurs in summer rather than in spring (March–May), as was previously thought. The female population consisted of the complete range of reproductive age classes in August– September. C. tripartitus also appears to be univoltine. However, this species has two adult activity periods: a peak activity in spring when most oviposition occurs, and another in autumn when the new generation emerges. With the onset of winter, C. tripartitus adults cease reproductive development and females over winter in a nulliparous stage.

      • OWNED MEDIA IN TWITTER OF MULTINATIONAL FIRMS: TO CENTRALIZE OR TO DECENTRALIZE?

        Nora Lado,Manuel Ceballos,Angel Garcia-Crespo 글로벌지식마케팅경영학회 2018 Global Marketing Conference Vol.2018 No.07

        There is scarcity of studies on social media strategy, and their appropriate implementation, applied to the case multinational corporations. In particular; there is a lack of studies adopting a cross-cultural approach (Okazaki and Taylor, 2013). Behind this fact is the assumption that, in general, multinational corporations adopt a global strategy that does not fit well with the personalized nature of social media. From the perspective of social media management, there are a kind of dilemma between the adoption of a centralized and standardized content generation and diffusion approach vis ? vis adopting a decentralization orientation at country level or even a more local level. Berthon, Pitt, Plangger, and Shapiro (2012) signal the challenge of standardizing corporate content in social media and point out the advantage of take into consideration the specificities of different cultures and countries. We found a tension between two trends, for one hand social media implies co-creation and the sharing the power between the firm and their customer, while global integrated marketing communications follow precisely the opposite route. This research was conducted to examine the influence of centralization degree of social media communication towards online customer. We develop an empirical study applied to more than 160 corporate Twitter accounts from Iberoamerican countries. These accounts are the universe of Spanish corporates accounts of a set of the most important global automobile brands over a two-month study period. We use post-level engagement metric as measure of consumers’ attitudinal responses to corporate tweets. The results indicate that online customer engagement is affected by the type of the social media account of the brand (global, country, distributor, event specific). A strategy of issuing tweets from more general and global account result in a greater impact on customer engagement. In general, it seems that a centralized strategy obtains more effect in the number of obtained retweets even controlling by content topic, sender and post characteristic. This research has important implications for Digital Managers of corporations in terms of better understanding and improving corporates’ strategy in the social media communication channels.

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