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      • KCI등재

        Hindi Correspondence of Bengali Nominal Suffixes

        Chatterji, Sanjay Korea Multimedia Society 2021 The journal of multimedia information system Vol.8 No.4

        One bottleneck of Bengali to Hindi transfer based machine translation system is the translation of suffixes of noun. The appropriate translation of a nominal suffix often depends on the semantic role of the corresponding noun chunk in the sentence. With the availability of a high performance Bengali morphological analyzer and a basic Bengali parser it is possible to identify the role of each noun chunk. This information may be used for building rules for translating the ambiguous nominal suffixes. As there are some similarities between the uses of Bengali and Hindi nominal suffixes we find that the rules may be identified by linguistically analyzing corpus data. In this paper, we identify rules for the ambiguous four Bengali nominal suffixes from corpus data and evaluate their performances. This set of rules is able to resolve a majority of the nominal suffix ambiguities in Bengali to Hindi transfer based machine translation system. Using the rules, we are able to translate 98.17% Bengali nouns correctly which is much better than the baseline ILMT system's accuracy of 62.8%.

      • KCI등재

        Study of the effect of the herbal composition SR2004 on hemoglobin A1c, fasting blood glucose, and lipids in patients with type 2 diabetes mellitus

        Sumit Chatterji,Dov Fogel 한국한의학연구원 2018 Integrative Medicine Research Vol.7 No.3

        Background: Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by raised blood glucose levels and peripheral insulin resistance. It is an increasingly prevalent global healthcare concern. Conventional treatment options are limited and in this context, there is renewed interest in evaluating the clinical and biological effects of traditional therapies. We assess the effect of a new herbal composition SR2004 on the hemoglobin A1c (HbA1c), fasting blood glucose, and lipid profiles of patients with T2DM. Methods: This is a single center, unblinded, prospective interventional study conducted in Israel. The composition SR2004 includes Morus alba, Artemisia dracunculus, Urtica dioica, Cinnamomum zeylanicum, and Taraxacum officinale. One hundred and nineteen patients with diagnosed T2DM were enrolled and received SR2004 in addition to their usual medications. HbA1c, fasting blood glucose, and lipid profiles at 12 weeks were compared with baseline. In addition, the tolerability and side effects of SR2004 were recorded. Results: One hundred and three patients completed 12 weeks of follow-up (87%) and were included in the results. At 12 weeks, HbA1c reduced from 9.0% to 7.1% (22%; p < 0.0001), mean blood glucose decreased from 211 mg/dL to 133 mg/dL (37% reduction; p < 0.0001), mean total cholesterol to 185 mg/dL (13% reduction; p < 0.01) and mean serum triglycerides to160 mg/dL (a reduction of 40% from baseline; p < 0.001). Twelve patients (12%) had no response with SR2004 supplementation. In addition, of thirteen patients who took insulin at baseline, five required only oral hypoglycemics and another five reduced their daily insulin requirements by 30% at 12 weeks. Clinical observations included improvements in vasculopathy, including reversal of established retinopathic changes in two patients. No major adverse effects were observed, with minor abdominal symptoms reported in sixteen patients (16%). Conclusion: SR2004 supplementation significantly reduced HbA1c, blood glucose, and lipids with good tolerability and no observed adverse interactions with conventional medications. Some interesting findings relating to the reversal of microvascular phenomena warrant further research to elucidate the mechanisms of action of this novel composition.

      • KCI등재

        ppGpp: Stringent Response and Survival

        Dipankar Chatterji,Vikas Jain,Manish Kumar 한국미생물학회 2006 The journal of microbiology Vol.44 No.1

        Adaptation to any undesirable change in the environment dictates the survivability of many microorganisms, with such changes generating a quick and suitable response, which guides the physiology of bacteria. During nutritional deprivation, bacteria show a stringent response, as characterized by the accumulation of (p)ppGpp, resulting in the repression of stable RNA species, such as rRNA and tRNA, with a concomitant change in colony morphology. However, genes involved in amino acid biosynthesis become over-expressed to help bacteria survive under such conditions. The survivability of pathogenic bacteria inside a host cell also depends upon the stringent response demonstrated. Therefore, an understanding of the physiology of stringent conditions becomes very interesting in regulation of the growth and persistence of such invading pathogens.

      • SCOPUSKCI등재

        Tracing the Variation in Physiological Response to Rifampicin Across the Microbial Spectrum

        Dey, Abhinav,Chatterji, Dipankar The Korean Society for Microbiology 2012 Journal of Bacteriology and Virology Vol.42 No.2

        Rifampicin is an acknowledged inhibitor of bacterial RNA polymerase. We observed that there exists a substantial variation in the basal-level tolerance to rifampicin across microbial species. A number of mechanisms have come to light which depict the molecular aspects of the behavior of an individual bacterial cell towards rifampicin. This review assesses the current knowledge about rifampicin and conjectures about the probable aspects of rifampicin which remain unexplored.

      • Computer-based Automated System for Determining the Characteristics, Losses and Efficiency of Separately Excited DC Motors

        Kaur, Puneet,Chatterji, S. Journal of International Conference on Electrical 2012 Journal of international Conference on Electrical Vol.1 No.4

        This paper provides essential information on research completed with the aim to develop a 'dc motor test and analysis platform' which can be used to provide dc motor characteristics, calculate losses and efficiency, and also work as a dc motor speed controller. A user can test a given dc motor for these analyses by practicing different conventional methods, but, the concept discussed in this paper, reveals how intelligent integration of all these analyses can be done with a single user friendly automated setup. Integration has been accomplished by a technique that can accommodate all types of dc motors with different ratings at various loading conditions. However, experimentally measured results of a 0.5HP separately excited dc motor using the discussed scheme are presented in the paper. Also, a comparison of the methodology of this system with conventional techniques has also been elaborated on to show the effectiveness of the system.

      • SCIESCOPUSKCI등재

        ppGpp: Stringent Response and Survival

        Jain Vikas,Kumar Manish,Chatterji Dipankar The Microbiological Society of Korea 2006 The journal of microbiology Vol.44 No.1

        Adaptation to any undesirable change in the environment dictates the survivability of many microorganisms, with such changes generating a quick and suitable response, which guides the physiology of bacteria. During nutritional deprivation, bacteria show a stringent response, as characterized by the accumulation of (p)ppGpp, resulting in the repression of stable RNA species, such as rRNA and tRNA, with a concomitant change in colony morphology. However, genes involved in amino acid biosynthesis become over-expressed to help bacteria survive under such conditions. The survivability of pathogenic bacteria inside a host cell also depends upon the stringent response demonstrated. Therefore, an understanding of the physiology of stringent conditions becomes very interesting in regulation of the growth and persistence of such invading pathogens.

      • SCOPUSKCI등재
      • KCI등재

        The Production of Xanthan from Brewer’s Spent Grain

        Chetia Rajiv,Bharadwaj Bhriganka,Dey Rahul,Chatterji Biswa Prasun 한국미생물·생명공학회 2023 한국미생물·생명공학회지 Vol.51 No.4

        Sugar or dextrose increases the cost of production of xanthan gum by Xanthomonas campestris. Brewers’ Spent Grain (BSG) was chosen as a source of fermentable sugars. BSG is a significant industrial by-product generated in large quantities from the breweries. Primarily used as animal feed due to its high fiber and protein content, BSG holds great potential as an economically and ecologically sustainable substrate for fermenting biomolecules. This study explores BSG's potential as a cost-effective carbon source for producing xanthan, utilizing Xanthomonas campestris NCIM 2961. An aqueous extract was prepared from BSG and inoculated with the bacterium under standard fermentation conditions. After fermentation, xanthan gum was purified using a standard protocol. The xanthan yield from BSG media was compared to that from MGYP media (control). The fermentation parameters, including pH, temperature, agitation and duration were optimized for maximum xanthan gum yield by varying them at different levels. Following fermentation, the xanthan gum was purified from the broth by alcoholic precipitation and then dried. The weight of the dried gum was measured. The obtained xanthan from BSG under standard conditions and commercial food-grade xanthan were characterized using FTIR. The highest xanthan yields were achieved at 32℃, pH 6.0, and 72 h of fermentation at 200 rpm using BSG media. The FTIR spectra of xanthan from BSG media closely resembled that of commercial food-grade xanthan. The results confirm the potential of BSG as a cost-effective alternative carbon source for xanthan production, thereby reducing production costs and solid waste.

      • KCI등재

        Anti-proliferative and angio-suppressive effect of Stoechospermum marginatum (C. Agardh) Kutzing extract using various experimental models

        Rashmi Vinayak,Shilpa Puttananjaiah,Anil Chatterji,Bharati Salimath 한국영양학회 2014 Nutrition Research and Practice Vol.8 No.4

        BACKGROUND/OBJECTIVES: Abundant consumption of seaweeds in the diet is epidemiologically linked to the reduction in risk of developing cancer. In larger cases, however, identification of particular seaweeds that are accountable for these effects is still lacking, hindering the recognition of competent dietary-based chemo preventive approaches. The aim of this research was to establish the antiproliferative potency and angiosuppressive mode of action of Stoechospermum marginatum seaweed methanolic extract using various experimental models. MATERIALS/METHODS: Among the 15 seaweeds screened for antiproliferative activity against Ehrlich ascites tumor (EAT) cell line, Stoechospermum marginatum extract (SME) was found to be the most promising. Therefore, it was further investigated for its anti-proliferative activity in-vitro against choriocarcinoma (BeWo) and non-transformed Human embryonic kidney (HEK 293) cells, and for its anti-migratory/tube formation activity against HUVEC cells in-vitro. Subsequently, the angiosuppressive activity of S. marginatum was established by inhibition of angiogenesis in in-vivo (peritoneal angiogenesis and chorioallantoic membrane assay) and ex-vivo (rat cornea assay) models. RESULTS: Most brown seaweed extracts inhibited the proliferation of EAT cells, while green and red seaweed extracts were much less effective. According to the results, SME selectively inhibited proliferation of BeWo cells in-vitro in a dose-dependent manner, but had a lesser effect on HEK 293 cells. SME also suppressed the migration and tube formation of HUVEC cells in-vitro. In addition, SME was able to suppress VEGF-induced angiogenesis in the chorio allantoic membrane, rat cornea, and tumor induced angiogenesis in the peritoneum of EAT bearing mice. A decrease in the microvessel density count and CD31 antigen staining of treated mice peritoneum provided further evidence of its angiosuppressive activity. CONCLUSIONS: Altogether, the data underline that VEGF mediated angiogenesis is the target for the angiosuppressive action of SME and could potentially be useful in cancer prevention or treatment involving stimulated angiogenesis.

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