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- 저자 : Chanuk Yoo (검색결과 7 건)
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Bioelectrical impedance analysis for severe stroke patients with upper extremity hemiplegia
Yoo, Chanuk,Kim, Jaehyung,Yang, Yeongae,Lee, Jinsu,Jeon, Gyerok The Society of Physical Therapy Science 2016 JOURNAL OF PHYSICAL THERAPY SCIENCE Vol.28 No.10
<P>[Purpose] This study is to analyze bioimpedance parameters and occupational assessment for severe stroke patients with upper extremity hemiplegia. [Subjects and Methods] Experimental subjects were 20 hemiplegic stroke patients receiving rehabilitation therapy between November to October, 2015. Prediction marker (PM), and phase angle (θ), a nd characteristic frequency (<I>fc</I>) were measured using bioelectrical impedance spectroscopy (MultiScan 5000). Bioelectrical impedance vector analysis (BIVA) was also obtained from the bioimpedance data. Then, these values were compared with occupational assessment tools. [Results] A significant differences in PM, θ, <I>fc</I>, and BIVA were observed between paretic region and non-paretic region of 5 severe stroke patients. These results were in good agreement with occupational assessment (pinch and hand grip strength, and ADL by MBI). [Conclusion] There were significant differences in impedance parameters between paretic region and non-paretic region of 5 severe stroke patients with upper extremity hemiplegia. Thus, the BIA could be useful tool for evaluating hemiplegic stroke patients receiving the rehabilitation therapy in the clinical application.</P>
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Yoo, Chanuk,Yang, Yeongae,Baik, Sungwan,Kim, Jaehyung,Jeon, Gyerok Korea Multimedia Society 2017 멀티미디어학회논문지 Vol.20 No.2
For many stroke patients undergoing rehabilitation therapy, there is a need for indicator for evaluating the body function in paretic and non-paretic regions of stroke patients quantitatively. In this paper, the function of muscles and cells in paretic and non-paretic regions of severe and mild hemiplegic stroke patients was evaluated using multi-channel bioelectrical impedance spectroscopy. The paretic and non-paretic regions of severe and mild stroke patients were quantitatively assessed by using bioelectrical impedance parameters such as prediction marker (PM), phase angle (${\theta}$), characteristic frequency ($f_c$), and bioelectrical impedance vector analysis (BIVA). The mean values of impedance vector were significantly discriminated in all comparisons (severe-paretic, severe-non-paretic, mild-paretic, and mild-non-paretic). The bioelectrical impedance parameters were proved to be a very valuable tool for quantitatively evaluating the paretic and non-paretic regions of hemiplegic stroke patients.
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Yoo, Jisang,Lee, DaeYong,Gujrati, Vipul,Rejinold, N. Sanoj,Lekshmi, Kamali Manickavasagam,Uthaman, Saji,Jeong, Chanuk,Park, In-Kyu,Jon, Sangyong,Kim, Yeu-Chun Elsevier 2017 Journal of controlled release Vol.246 No.-
<P><B>Abstract</B></P> <P>Cell-penetrating peptides (CPPs) have been widely used to deliver nucleic acid molecules. Generally, CPPs consisting of short amino acid sequences have a linear structure, resulting in a weak complexation and low transfection efficacy. To overcome these drawbacks, a novel type of CPP is required to enhance the delivery efficacy while maintaining its safe use at the same time.</P> <P>Herein, we report that a bioreducible branched poly-CPP structure capable of responding to reducing conditions attained both outstanding delivery effectiveness and selective gene release in carcinoma cells. Branched structures provide unusually strong electrostatic attraction between DNA and siRNA molecules, thereby improving the transfection capability through a tightly condensed form. We designed a modified type of nona-arginine (mR9) and synthesized a branched-mR9 (B-mR9) using disulfide bonds. A novel B-mR9/pDNA polyplex exhibited redox-cleavability and high transfection efficacy compared to conventional CPPs, with higher cell viability as well. B-mR9/VEGF siRNA polyplex exhibited significant serum stability and high gene-silencing effects <I>in vitro</I>. Furthermore, the B-mR9 polyplex showed outstanding tumor accumulation and inhibition ability <I>in vivo</I>. The results suggest that the bioreducible branched poly CPP has great potential as a gene delivery platform.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
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( Kwak Hosoung ),( Yoo Chanuk ) 대한통합의학회 2020 대한통합의학회지 Vol.8 No.2
Purpose : This study aims to evaluate the correlation of cognitive function, activities of daily living (ADL), and driving performance in stroke hemiplegic patients residing in Korea. Methods : Subjects of the study were 18 stroke hemiplegic patients admitted to hospitals situated in Seoul. A clock drawing test (CDT), a modified Barthel index (MBI), and a virtual reality driving simulator (Eca faros-driving simulator) were used to examine their cognitive function, their ADL ability, and their driving skills, respectively. Results : Driving skills of stroke hemiplegic patients were shown to be associated with the CDT evaluation tool (r=-.777) (p< .001), but they were found to have any correlation with MBI (r=-.022) (p >.05). Additionally, an individual’s CDT showed that the driving simulator evaluation result (pass/fail) could be discriminated with a sensitivity of 100.0 %, a specificity of 40.0 %, and an accuracy of 66.7 %. The result confirmed that the CDT is a useful evaluation tool for screening driving ability in people with stroke. But the MBI did not show any significant results (sensitivity of 62.5 %, specificity of 40.0 %, and predicted the results of the simulator with 50.0 % of accuracy) (p>.05). Conclusion : This study shows that cognitive function influences the driving performance in people with stroke. Driving skills of stroke hemiplegic patients are seen to be highly related to CDT. In the field of driving rehabilitation, these findings could be useful for evaluating driving skills relating to CDT. Furthermore, the study results will set a guideline for domestic occupational therapists to use the evaluation tool for assessing driving abilities in people with stroke.
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전력산업에서 VR/AR 기술동향 및 공통 플랫폼 구성방안 연구
채창훈,최민희,유은근,임찬욱,박진우,정남준,Chae, Changhun,Choi, Minhee,Yoo, Eungeun,Lim, Chanuk,Park, Jinwoo,Jung, Namjoon 한국전력공사 2016 KEPCO Journal on electric power and energy Vol.2 No.3
최근 세계적인 ICT 기업들이 가상현실 (VR)과 증강현실 (AR) 기술의 생태계 확장을 위하여 많은 노력을 하고 있다. 기존의 엔터테인먼트 분야뿐만 아니라 교육, e-커머스 등 다양한 산업으로 발전시키고 있으며, 전력, 에너지 분야 또한 예외가 아니다. 전력산업에서도 VR/AR 기술 적용을 통한 어플리케이션의 증가가 예상되고 있어, 관련 기술 요소들을 데이터와 프로세스 관점에서 표준화하여 재사용성을 높이고, 기존 Legacy 시스템 연동과 보안 등을 고려한 플랫폼 구성을 선행함으로써 어플리케이션 개발에 효율과 편의성을 극대화할 수 있을 것이다. 본 논문에서는 VR, AR의 기술개발 동향 및 전력산업에서의 적용가능성과 플랫폼의 필요성, 구성요소들을 도출하여 기능적으로 완성도 높고 사용이 편리한 다양한 전력 VR/AR 플랫폼을 제공함으로써 포켓몬고 (Pokemon GO)와 같은 전력분야의 혁명적인 킬러 어플리케이션의 도출과 플랫폼 표준을 이끌어갈 것으로 기대한다. Recently, many ICT companies are trying to expand the ecosystem of VR (Virtual Reality) and AR (Augmented Reality). They are developing a variety of industries such as entertainment, education, e-commerce and so on. There is also contains the power, energy field. And application related with VR/AR will increase in power industry. Thus, Platform is necessary because there are problems such as re-use, interface with legacy system and security. We can expect the convenience and efficiency by developing VR/AR power platform. In this paper, we will discuss the trends of VR/AR technologies, possibilities of VR/AR in energy field, essential elements of VR/AR power platform. In the future, we expect to lead standards of VR/AR in energy and to develop a killer application such as Pokemon GO.
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