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- 저자 : Cañete, Francisco J. (검색결과 4 건)
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Cañete Oscar M.,El-Haj-Ali Mouhamad,Fereczkowski Michal 대한청각학회 2024 Journal of Audiology & Otology Vol.28 No.2
Background and Objectives: Otoacoustic emissions (OAEs) are low-intensity sounds generated by the cochlea and associated with the function of the outer hair cells. Since OAE measurements do not require active participation of a listener, OAEs are considered an objective measure of cochlear function. While distortion-product OAEs (DPOAEs) are commonly used in clinical practice, limited information is available on the performance of various clinical devices. This study compared two commercial clinical devices, Titan and Eclipse from Interacoustics, and collected normative data for DPOAEs in people with normal hearing. The data collection and analysis were focused on signal and noise amplitudes as well as signal-to-noise ratios (SNRs).Subjects and Methods: Sixty-three participants with normal hearing (age 23.2±2.0 years) were included in the study. DPOAEs were measured at 31 frequencies ranging from 500 to 10,000 Hz.Results: DPOAE amplitude differed across frequencies. Additionally, a high number of unreliable responses were observed at the edge frequencies (<828 Hz and >6,072 Hz). There were no significant differences between the two devices in terms of DPOAE amplitudes, but the recorded-noise levels (amplitude) differed significantly. SNRs of the recorded OAEs were frequency dependent (higher frequencies showed larger SNRs), and significant differences in terms of SNR were found between the two devices.Conclusions: Despite the above-mentioned differences, the OAEs recorded with both devices met the pass criteria for the SNR (≥6 dB) consistently across frequencies, and thus the differences do not compromise the test outcomes. The frequency dependence of the OAE amplitudes and the corresponding SNRs may be relevant for clinical practice.
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Edwin Jadulco Cañete,Cherrie Mae Sison-Peña,Cecilia Alegado Jimeno 대한내분비학회 2014 Endocrinology and metabolism Vol.29 No.4
Background: Thyroid nodules may harbor cancer in 5% to 15% of cases. Specific clinical and sonographic features predictive of malignancy have been investigated in various populations, but due to differences in epidemiology, risk factors and iodine nutrition status, these predictors may not be valid in the Philippines. This study determined the clinicopathological, biochemical, and sonographic features of thyroid nodules predictive of malignancy among adult Filipino patients at the University of the Philippines-Philippine General Hospital (UP-PGH). Methods: We reviewed the medical records of Filipino patients ≥19 years of age who underwent thyroid surgery in UP-PGH from 2008 to 2011. Results: A total of 837 of 1,670 patients (50.1%) were enrolled in the study, which included 417 benign and 420 malignant tumors. The mean age at diagnosis was 38±11 years, with female predominance. Multiple logistic regression analysis showed that the presence of a hard or firm nodule (odds ratio [OR], 58.8, P<0.001; OR, 12.8, P<0.001), presence of microcalcifications (OR, 11.1; P<0.001), irregular margins on ultrasound (OR, 4.5; P<0.001), and absence of associated symptoms (OR, 2.3; P<0.002) increased significantly the likelihood of thyroid malignancy. Conclusion: Similar to international data, the absence of associated symptoms, firm to hard thyroid nodules, and the presence of microcalcifications and irregular margins were significant predictors of thyroid malignancy.
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Channel Estimation for OFDM-based Indoor Broadband Power Line Communication Systems
Cortés, José A.,Cañete, Francisco J.,Díez, Luis 한국통신학회 2023 Journal of communications and networks Vol.25 No.2
State-of-the-art indoor broadband power line com-munications (PLC) systems use orthogonal frequency divi-sion multiplexing (OFDM) signals with constellations up to10 bits/symbol, which makes channel estimation a key aspect. This paper focuses on the initial channel estimation used in thepayload, which might be further adapted by means of a decision-directed strategy. This initial estimate has to be computed on aper-frame basis and can be accomplished from the preamble, theheader symbol (assuming that it has been correctly decoded) orfrom a combination of both. This work proposes simple channelestimation techniques for this problem and derives their mostappropriate parameters. They are compared with the linearminimum mean squared-error (LMMSE) estimator and otherscommonly used in wireless scenarios by considering both theirperformance and computational complexity. The factors limitingthe performance of the estimators based on the preamble and theheader symbols are analyzed and the implications of the differ-ences between PLC and wireless channels, such as the absenceof fading, in the design of estimation techniques that requireknowledge of the channel statistics are discussed. A performanceanalysis of the considered techniques is accomplished in a set of171 measured indoor PLC channels. Obtained results indicatethat estimators from the header perform better than those basedon the preamble symbols and we provide a computationallysimple estimator that gives nearly optimum performance bycombining estimates from both the preamble and the headersymbols.
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Age of Postmenopause Women: Effect of Soy Isoflavone in Lipoprotein and Inflammation Markers
Gladys Roxana Rocha Barrasa,Natalia González Cañete,Luis Emilio Valladares Boasi 대한폐경학회 2018 대한폐경학회지 Vol.24 No.3
Objectives: Menopause is associated with adverse metabolic changes in plasma lipoprotein and inflammation markers. Estrogens have beneficial effects on lipid metabolism and inflammation. Isoflavones (ISO) have structurally similar to estradiol. Our objective was analize the effect of soy-ISO on serum lipid and inflammatory markers (sP-selectin and sCD40L) in postmenopausal women.Methods: A 12-week randomized, double-blind, placebo-controlled intervention with soy-ISO (50 mg, twice daily) was conducted in 35 healthy postmenopausal women (55-72 years old). The women were divided in 2 groups: 20 were allocated to soy-ISO, and 15 to a placebo group.Results: The changes of total cholesterol (TC), triglycerides, low-density lipoproteins-cholesterol (LDL-C), high-density lipoprotein-cholesterol, Apo-A1, sP-selectin and sCD40L in 2 groups before and after 12-week treatment showed no statistical significance. In subgroup analysis, soy-ISO supplementation significantly decreased the levels of TC, LDL-C and sCD40L in women under 65 years old, and with null effects on serum lipid and inflammation markers in women over 65 years old. Conclusions: Soy-ISO did not significantly favorable effects on the lipid profile and inflammatory markers in postmenopausal women. However, in women under 65 years of age, soy-ISO significantly decreased the TC, LDL-C and sCD40L, whereas, no effects on lipid profile and inflammation markers in women over 65 years old were observed.
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