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RISS 인기검색어
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- 저자 : Browne Andrew W. (검색결과 4 건)
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Melvin Lewis,Kenon A. Brown,Andrew C. Billings,Zachary W. Arth 글로벌지식마케팅경영학회 2022 Journal of Global Sport Management Vol.7 No.4
This study explored causal relationships and moderation effects in the context of the National Football League (NFL; American football), employing 732 respondents from a pair of nationally representative samples to determine the degree of similarity or difference between feelings about the United States as it relates to American consumption of the 2018 Winter Olympics and the 2018 NFL season. Media consumption’s influence on one’s feelings of nationalism was stronger for Winter Olympic fans compared to NFL fans, yet no differences were detected on patriotism and internationalism factors. Academicians and sport marketers should regard these findings as a warrant for considering exploring cause-related sports marketing (CRSM) techniques. Differences in nationalism findings suggest that the comparisons between nations are exclusively an Olympics-based phenomena while the National Football League seems to be much more insular in that regard.
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Zhang, Huagui,Kim, Yun Kon,Hunter, Timothy N.,Brown, Andrew P.,Lee, Jae W.,Harbottle, David Royal Society of Chemistry 2017 Journal of Materials Chemistry A Vol.5 No.29
<▼1><P>Organo-clay–HCF particles are used to remove Cs<SUP>+</SUP> from aqueous environments. Cs-Loaded particles were subsequently separated <I>via</I> column flotation.</P></▼1><▼2><P>The selective capture of mobile radioactive nuclides, such as <SUP>137</SUP>Cs<SUP>+</SUP>, is crucial to the clean-up and remediation of contaminated environments. While remediation remains a challenging task, the current study considers novel organo-clay composites containing potassium copper hexacyanoferrate (KCuHCF) as a viable option for large-scale clean-up. A three-step synthesis has been demonstrated whereby pristine montmorillonite clay was readily modified to incorporate KCuHCF nanoparticles for enhanced and selective Cs<SUP>+</SUP> removal from aqueous environments. Alkyldiamine (DT) was used as an organic modifier to intercalate the clay and provided chelating sites to anchor copper onto the clay matrix, from which KCuHCF nanoparticles were subsequently grown <I>in situ via</I> the coordination of hexacyanoferrate precursors with the immobilized copper ions. The organo-clay–HCF composite particles exhibited a superior Cs<SUP>+</SUP> adsorption capacity (<I>q</I>m = 206 mg g<SUP>−1</SUP>), twice that of the pristine clay. The enhanced performance also extended to high Cs<SUP>+</SUP> selectivity in seawater, with the organo-clay–HCF composites demonstrating Cs<SUP>+</SUP> selectivity values in excess of 10<SUP>5</SUP> mL g<SUP>−1</SUP>, two orders of magnitude greater than the pristine clay. Organo modification of the clay particles reduced the particle wettability, thus facilitating the separation of Cs-loaded composite particles from aqueous environments by collector-less flotation. Batch flotation experiments showed recovery efficiencies of the Cs-loaded composite particles of up to 90%, which was in great contrast to the low recovery of less than 15% for the Cs-loaded pristine montmorillonite. The current study provides a new concept for the treatment of contaminated aqueous environments.</P></▼2>
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Meeting Report: Translational Advances in Cancer Prevention Agent Development Meeting
Mark Steven Miller,Peter J. Allen,Powel H. Brown,Andrew T. Chan,Margie L. Clapper,Roderick H. Dashwood,Shadmehr Demehri,Mary L. Disis,Raymond N. DuBois,Robert J. Glynn,Thomas W. Kensler,Seema A. Khan 대한암예방학회 2021 Journal of cancer prevention Vol.26 No.1
The Division of Cancer Prevention of the National Cancer Institute (NCI) and the Office of Disease Prevention of the National Institutes of Health co-sponsored the Translational Advances in Cancer Prevention Agent Development Meeting on August 27 to 28, 2020. The goals of this meeting were to foster the exchange of ideas and stimulate new collaborative interactions among leading cancer prevention researchers from basic and clinical research; highlight new and emerging trends in immunoprevention and chemoprevention as well as new information from clinical trials; and provide information to the extramural research community on the significant resources available from the NCI to promote prevention agent development and rapid translation to clinical trials. The meeting included two plenary talks and five sessions covering the range from pre-clinical studies with chemo/immunopreventive agents to ongoing cancer prevention clinical trials. In addition, two NCI informational sessions describing contract resources for the preclinical agent development and cooperative grants for the Cancer Prevention Clinical Trials Network were also presented.
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Genome editing in the treatment of ocular diseases
Choi Elliot H.,Suh Susie,Sears Avery E.,Hołubowicz Rafał,Kedhar Sanjay R.,Browne Andrew W.,Palczewski Krzysztof 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-
Genome-editing technologies have ushered in a new era in gene therapy, providing novel therapeutic strategies for a wide range of diseases, including both genetic and nongenetic ocular diseases. These technologies offer new hope for patients suffering from previously untreatable conditions. The unique anatomical and physiological features of the eye, including its immune-privileged status, size, and compartmentalized structure, provide an optimal environment for the application of these cutting-edge technologies. Moreover, the development of various delivery methods has facilitated the efficient and targeted administration of genome engineering tools designed to correct specific ocular tissues. Additionally, advancements in noninvasive ocular imaging techniques and electroretinography have enabled real-time monitoring of therapeutic efficacy and safety. Herein, we discuss the discovery and development of genome-editing technologies, their application to ocular diseases from the anterior segment to the posterior segment, current limitations encountered in translating these technologies into clinical practice, and ongoing research endeavors aimed at overcoming these challenges.
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