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위봉애 충남대학교 의과대학 지역사회의학연구소 1985 충남의대잡지 Vol.12 No.2
Cerebrospinal fluid levels of creatine kinase(CK), glutamate oxaloacetic transaminase(GOT) and lactate dehydrogenase(LDH) were measured in 8 acute stroke patients comprising 5 cortical strokes and 3 lacunar strokes. A marked elevation of CK was seen in cortical stroke compared to lacunar stroke and control group. No significant difference in cerebrospinal fluid levels of GOT and LDH was seen between the two kinds of strokes and control group. These findings suggests that cerebrospinal fluid levels of creatine kinase could be a useful diagnostic tool to distinguish cortical from lacunar stroke.
위봉애 충남대학교 의과대학 지역사회의학연구소 1986 충남의대잡지 Vol.13 No.2
Low-dose alternate day oral prednisone regimen was administered to seven myasthenic patients with improvements in six and remission in one patient. Improvement occured initially 60 days after start of prednisone, becoming maximal 5.8 months after the start of prednisone. The initial deterioration during prednisone treatment occured in one paient. Other side-effect of prednisone treatment occured in all patients and these included moon face, glucose intolerance, acne, gastrointestinal bleeding, osteoporosis, hypokalemia and infection.
위봉애 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.2
The author reviewed the cases of 22 patients with thalamic hemorrhage who were seen at the Chungnam National University Hospital between 1985 and 1987. The analysis was based on clinical-CT correlations. The age of the patients ranged from 35 years to 83 years(mean : 57 years). Sixteen(73%) were hypertensive. The size of hematoma was less than 10mm in 2 patients, 10-30mm in 14 patients and larger than 30mm in 6 patients. Impaired consciousness was observed in 77%. The prognosis seemed to be inversely proportional to the size of hematoma and the severity of consciousness impairment. Miosis with or without sluggish light reflex occurred in 6 patients and gaze preference in 4. Visual field defect was observed in I patient. Hemiparesis was associated in 95% of patients and hemisensory defect was confirmed in 13 patients among the 17 patients tested. Dysphasia and dysarthria occurred in 3 and 5 patients respectively.
피질뇌경색및 심부뇌경색에 있어서 뇌척수액 효소치의 진단적 가치
임민자,위봉애 충남대학교 의과대학 지역사회의학연구소 1988 충남의대잡지 Vol.15 No.2
The authors tested the value of CSF enzymes in the differential diagnosis between the cortical infarcts and the lacunar infarcts. From the CSF of 31 patients with acute cerebral infarct, the authors measured the levels of creatine kinase(CK), glutamate oxaloacetic transaminase(GOT), and lactate dehydrogenase(LDH). They composed 22 cortical infarcts aad 2 lacunar infarcts. Significant elevation of CK level was observed in cortical and lacunar strokes compared with that of the control group. But between the cortical and the lacunar groups difference was not significant and both GOT and LDH levers were found not to be elevated significantly in any group. These findings suggest that cerebrospinal fluid levels of CK, GOT, and LDH lack diagnostic value to distinguish cortical from lacunar stroke though they can differentiate infarcts from the normal ones.
전종훈,정진상,위봉애 충남대학교 의과대학 지역사회의학연구소 1989 충남의대잡지 Vol.16 No.2
To evaluate the prognosis of primary pontine hemorrhage and its related factors the clinical and radiological features of 26 patients were analyzed. The features of survival group (9 cases) and non-survival group (17 cases) were not different in age and sex distribution. Univariately significant factors suggesting poor prognosis were as follows: 1) Lower level of consciousness at the first evaluation 2) breathing abnormalities suggesting brainstem dysfunctions 3) high systolic blood pressure 4) size of hematoma across the midine of the pons and 6) associated ventricular dilatation.
( Bong Young Kim ),( Ji Eun Kim ),( Hyun Joo Pai ),( Seong Heon Wie ),( Young Kyun Cho ),( Seung Kwan Lim ),( Sang Yop Shin ),( Joon Sup Yum ),( Jin Seo Lee ),( Ki Tae Kweon ),( Hyuck Lee ),( Hee Jin 대한내과학회 2011 대한내과학회 추계학술대회 Vol.2011 No.1
For the proper antibiotics treatment, identification of pathogen and antimicrobial susceptibility results are mandatory. In Korea, there was no recommendation for microbiological evaluation of community-acquired uncomplicated acute cystitis (CA-UAC) and little microbiological data was available on CA-UAC. Therefore, clinicians have treated CA-UAC based on microbiological data of community acquired uncomplicated acute pyelonephritis (CA-UAPN). In order to evaluate the applicability of CA-UAPNs` microbiological data for CA-UACs`, the comparison of antimicrobial susceptibility test between CA-UAC and CA-UAPN was performed. During 2008, 538 CA-UACs and 1265 CA-UAPNs were collected retrospectively from 14 hospitals (UTI research group) in Korea. Microbiological data were included in 137 CA-UACs (137/538, 25.5%) and 722 CA-UAPNs (722/1265, 57.1%). Escherichia coli was the most common pathogen in both group (83.9% (115/137) in CA-UAC vs. 92.6% (661/722) in CA-UAPN). The antimicrobial susceptibility tests for E. coli between CA-UACs and CA-UAPNs were analyzed. There were significant differences in resistance rates to ampicillin and ampicillin/sulbactam (46.9% vs. 37%, p=0.047; 81.7% vs. 57.1%, p<0.0001, respectively). In conclusion, there are significant differences in ampicillin and ampicillin/sulbactam resistance rates for E. coli between CA-UAC and CA-UAPN. CA-UAC treatment based on microbiological data of CA-UAPN should be cautious and microbiological evaluation for CA-UAC should be considered for proper treatment.