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全永鎬,李彬娜,林凞燮 弘益大學校 科學技術硏究所 2005 科學技術硏究論文集 Vol.16 No.-
Brand asset management to build powerful brand asset is needed to have more powerful comparative advantage. In this study, critical factors of the structure of brand asset are considered. For this purpose, the relationships between the brand asset and the structure of brand asset are evaluated. And measurement of the competitive power of the specific brand at the point of clients by describing the systematic measuring methodology of the brand asset and its applications is studied. And then, the model that can be used to solve and improve the general realities and level of brand management is proposed. For this, we recognized the strategic importance of brand asset and the brand asset management with previous studies. And we improved the model that showed that the increasing of brand competitive power makes purchasing intention and the brand loyalty increase at the point of clients by pointing out the limit of previous studies. With this improved model, we investigated the brand competitive power on digital electric home appliances about images, sounds, and communications. To test this model statistically, the structural equation model that is most popular in the latest is used. By using the result of this study, companies will be able to measure of their own and the other's brand competitive power and understand the method of benchmarking and the improvements. Moreover, the government will be able to draw up the plan and the system that support to secure the brand competitive power and bring up the global brand that have international competitive power.
색상 측정 기기를 이용한 복합레진 적층 수복과 단일 수복의 색상 비교 분석
송영상,김자현,이빈나,장지현,장훈상,황윤찬,오원만,황인남 大韓齒科保存學會 2012 Restorative Dentistry & Endodontics Vol.37 No.2
Objectives: This study analyzed the difference in color caused by different thickness in enamel layer of composite resins when applied with single and layering placement technique, and evaluated if the results agreed with the shade guide from the manufacturers to verify reliability of the color matching process of the manufacturers. Materials and Methods: For single composite resin samples, 6 mm diameter and 4 mm thickness cylindrical samples were fabricated using Ceram-X mono (DENTSPLY DeTrey) and CIE L*a*b* values were measured with spectrophotometer. Same process was done for layering compositie resin samples, making 3 dentinal shade samples, 4 mm thickness, for each shade using Ceram-X duo (DENTSPLY DeTrey) and enamel shade resins were layered in 2 mm thickness and CIE L*a*b* values were measured. These samples were ground to 0.2 mm thickness each time, and CIE L*a*b* values were measured to 1 mm thickness of enamel shade resin. Results: Color difference (△E*) between single and layering composite resin was 1.37 minimum and 10.53 maximum when layering thicknesses were between 1 mm and 2 mm and 6 out of 10 same shade groups suggested by manufacturer showed remarkable color difference at anythickness (△E* > 3.3). Conclusion: When using Ceram-X mono and duo for composite resin restoration, following the manufacturer's instructions for chossing the shade is not appropriate, and more accurate information for Ceram-X duo is needed on the variation and expression of the shades depending on the thickness of the enamel. (Restor Dent Endod 2012;37(2):84-89)
Influence of Hydrofluoric Acid on Soil Microorganisms and Physicochemical Properties of Soils
Lee, Youn Koung(이연경),Dong Sung Lee(이동성),Kyo Suk Lee(이교석),Dae Sung Jeon(전대성),Mi suk Park(박미숙),Ji Su Shin(신지수),Ji Won Goo(구지원),Soo Bin Kim(김수빈),Na Won Park(박나원),Ye Jin Park(박예진),So Jin Kim(김소정),Bo Koung 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.10
Lee, Joon-Hee,Whang, Jung-Bin,Youn, Na-Ri,Lee, Sun-Young,Lee, Hyang-Jung,Kim, Young-Jun,Koh, Kyung-Hee The Korean Society of Food Science and Nutrition 2009 Preventive Nutrition and Food Science Vol.14 No.3
In this study, we evaluated the phytochemical compositions of the fruits of the pear cactus, mulberry, and Korean black raspberry to determine how they related to antioxidant capacity. Specifically, the total soluble polyphenol, flavonoid and anthocyanin contents were determined, and the phenolic compounds were evaluated by HPLC. In addition, the antioxidant capacity was evaluated by electron paramagnetic resonance (EPR), SOD-like activity and nitrate scavenging activity. Korean black raspberry was found to have the highest level of phytochemicals, followed by mulberry and pear cactus (p<0.05). Furthermore, EPR revealed that Korean black raspberry extract (100 ${\mu}g$/mL) removed 78.6% of the superoxide radicals in a xanthin-xanthin oxidase. Additionally, when the removal of hydroxyl radicals was evaluated, the extract of pear cactus showed 50% scavenging activity at 1000 ${\mu}g$/mL. Korean black raspberry extract showed the highest SOD-like activity, which was 44% (p<0.05). Finally, the nitrate scavenging activity of both extracts of mulberry and Korean black raspberry were found to be 93%, while that of the pear cactus was 63% at pH 1.2 (p<0.05).
Lee, Jinwoo,Na, Hyon Bin,Kim, Byoung Chan,Lee, Jin Hyung,Lee, Byoungsoo,Kwak, Ja Hun,Hwang, Yosun,Park, Je-Geun,Gu, Man Bock,Kim, Jaeyun,Joo, Jin,Shin, Chae-Ho,Grate, Jay W.,Hyeon, Taeghwan,Kim, Jungb Royal Society of Chemistry 2009 Journal of materials chemistry Vol.19 No.42
<P>A magnetically-separable and highly-stable enzyme system was developed by adsorption of enzymes in superparamagnetic hierarchically ordered mesocellular mesoporous silica (M-HMMS) and subsequent enzyme crosslinking. Superparamagnetic nanoparticles were homogeneously incorporated into hierarchically-ordered mesocellular mesoporous silica (HMMS) by the decomposition of a preformed iron propionate complex. The size of the incorporated superparamagnetic nanoparticles was around 5 nm, generating a magnetically separable host with high pore volumes and large pores (M-HMMS). α-chymotrypsin (CT) was adsorbed into M-HMMS with high loading (∼30 wt%) in less than 30 minutes. Glutaraldehyde (GA) treatment of adsorbed CT resulted in nanometer scale crosslinked enzyme aggregates in M-HMMS (CLEA-M). The activity of these CT aggregates in M-HMMS (CLEA-M-CT) was 34 times than that of simply adsorbed CT in M-HMMS, due to an effective prevention of enzyme leaching during washing <I>via</I> a ship-in-a-bottle approach. CLEA-M-CT maintained the initial activity not only under shaking (250 rpm) for 30 days, but also under recycled uses of 35 times. The same approach was employed for the synthesis of CLEA-M of lipase (CLEA-M-LP), and proven to be effective in improving the loading, activity, and stability of enzyme when compared to those of adsorbed LP in M-HMMS.</P> <P>Graphic Abstract</P><P>Crosslinked enzyme aggregates in magnetitie-coated mesoporous silica, fabricated <I>via</I> a two-step procedure of enzyme adsorption and crosslinking, were highly active, highly stable, and easily recyclable using a magnet. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=b909109b'> </P>
Anti-inflammatory and Osteogenic Effects of Calcium Silicate–based Root Canal Sealers
Lee, Bin-Na,Hong, Ji-Uk,Kim, Se-Min,Jang, Ji-Hyun,Chang, Hoon-Sang,Hwang, Yun-Chan,Hwang, In-Nam,Oh, Won-Mann Elsevier 2019 JOURNAL OF ENDODONTICS - Vol.45 No.1
<P><B>Abstract</B></P> <P><B>Introduction</B></P> <P>An ideal root canal sealer creates a bacteria-resistant seal and exhibits antimicrobial activity, biocompatibility, and osteoconductivity. The aim of this study was to assess the effects of 3 root canal sealers on cell viability, inflammatory response, and osteogenic potential in MC3T3-E1 cells.</P> <P><B>Methods</B></P> <P>AH Plus (Dentsply Caulk, Milford, DE), MTA Fillapex (Angelus Solucxoes Odontologicas, Londrina, Brazil), and EndoSequence BC (Brasseler, Savannah, GA) were mixed according to the manufacturer's instructions, and samples were prepared as extraction media (final dilution: 1/10). Lipopolysaccharide (LPS) (100 ng/mL) treatment was used to induce an inflammatory response in this study. Cell viability was evaluated using the Water soluble tetrazolium-1 (WST-1) assay. The levels of inflammatory mediators (interleukin 6 and tumor necrosis factor alpha) and osteogenic marker genes (<I>ALP</I> and <I>OCN</I>) were measured by reverse-transcription polymerase chain reaction and real-time polymerase chain reaction. Osteogenic potential was evaluated by alkaline phosphatase staining and alizarin red staining.</P> <P><B>Results</B></P> <P>Calcium silicate–based sealers such as MTA Fillapex and EndoSequence BC showed strong cell viability compared with AH Plus. AH Plus, MTA Fillapex, and EndoSequence BC decreased the levels of LPS-induced inflammatory mediators (<I>P</I> < .05). The expression of osteogenic marker genes, alkaline phosphatase activity, and mineralized nodule formation decreased with LPS treatment. However, AH Plus and calcium silicate–based sealers increased the osteogenic potential reduced by LPS treatment (<I>P</I> < .05).</P> <P><B>Conclusions</B></P> <P>Calcium silicate–based sealers exhibit anti-inflammatory effects and induce osteogenic differentiation in MC3T3-E1 cells.</P> <P><B>Highlights</B></P> <P> <UL> <LI> We evaluated the biocompatibility, anti-inflammatory, and osteogenic effects of calcium silicate–based root canal sealers. </LI> <LI> Calcium silicate–based sealers showed good cell viability compared with epoxy resin–based sealer. </LI> <LI> The expression of osteogenic marker genes, ALP activity, and mineralized nodule formation decreased by lipopolysaccharide (LPS) treatment, but calcium silicate–based sealers and epoxy/amine resin–based sealer increased osteogenic potential and mineralization reduced by LPS treatment. </LI> </UL> </P>
Versatile PEG-derivatized phosphine oxide ligands for water-dispersible metal oxide nanocrystals
Na, Hyon Bin,Lee, In Su,Seo, Heonjin,Park, Yong Il,Lee, Jung Hee,Kim, Sang-Wook,Hyeon, Taeghwan Royal Society of Chemistry 2007 Chemical communications Vol.2007 No.48
<P>We report the simple synthesis of poly(ethylene glycol) (PEG)-derivatized phosphine oxide ligands for water-dispersible metal oxide nanocrystals.</P> <P>Graphic Abstract</P><P>We report the simple synthesis of poly(ethylene glycol) (PEG)-derivatized phosphine oxide ligands. The synthetic procedure is readily applicable to the large-scale production of uniformly-sized water-dispersible oxide nanocrystals from the ligand exchange reaction of the corresponding organic dispersible nanocrystals. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=b712721a'> </P>
Dental management of patients with X-linked hypophosphatemia
Lee, Bin-Na,Jung, Hye-Yoon,Chang, Hoon-Sang,Hwang, Yun-Chan,Hwang, In-Nam,Oh, Won-Mann The Korean Academy of Conservative Dentistry 2017 Restorative Dentistry & Endodontics Vol.42 No.2
X-linked hypophosphatemia (XLH) is a hereditary metabolic disease caused by the loss of phosphate through the renal tubules into the urine, and an associated decrease in serum calcium and potassium phosphate. Its dental features include spontaneous dental abscesses that occur in the absence of trauma or dental caries. The aim of this case report was to describe the dental problems of XLH patients and to evaluate limitations in their treatment. A 14 year old male and a 38 year old female with XLH were referred to the Department of Conservative Dentistry for endodontic treatment. The dental findings were periapical abscesses without obvious trauma or caries. Conservative endodontic treatment was performed in teeth with pulp necrosis and abscess. In case 1, the treated teeth showed improvements in bone healing, without clinical symptoms. However, in case 2, the implants and the treated tooth showed hypermobility, and the final restoration was therefore postponed. Early diagnosis, periodic examinations, and communication with the patient's pediatrician are important in the dental management of patients with XLH.