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Bian, Jin Long,Seo, Yong Jun,Kim, Geun Woo,Sung, Chang Hoon,Kumar, Shalendra,Lee, Chan Gyu,Koo, Bon Heun Elsevier 2011 Current Applied Physics Vol.11 No.1
<P><B>Abstract</B></P><P>Composites of 0.99La<SUB>0.7</SUB>(Ca<SUB><I>x</I></SUB>Sr<SUB>1–<I>x</I></SUB>)<SUB>0.3</SUB>MnO<SUB>3</SUB>/0.01SnO<SUB>2</SUB> (LCSMO/SnO<SUB>2</SUB>) (<I>x</I> = 0, 0.1, 0.2, 0.5, 0.7 and 1) were synthesized using solid-state reaction technique, and then characterized using the X-ray diffraction (XRD) and scanning electron microscopy (SEM). The XRD and SEM observations show the LCSMO and SnO<SUB>2</SUB> phases are separately distributed in the composites which indicate that there was no chemical interaction occurred during the sintering process. SnO<SUB>2</SUB> is mainly distributed at the grain boundaries and surfaces of the matrix. The resistivity of the composites was measured in the range of 100–350 K by using physical properties measurement system (PPMS). The applied magnetic field is 0T, 0.5T and 1T. Enhanced magnetoresistance (MR) within a wide temperature range was obtained. The observed variation of MR with varying Ca and Sr concentration has been qualitatively investigated.</P> <P><B>Highlights</B></P><P>► Low field magnetoresistance has potential application in highspeed electronic, magnetic and recording devices, etc. ► SnO<SUB>2</SUB> influence the electric and magnetic properties of the manganites composites. ► Enhanced room temperature magnetoresistance at low magnetic field.</P>
Structural Mechanisms of the Cooling Rate Effect on the Deformation Behaviors in Metallic Glasses
Bian Zhou,Ming‑fei Li,Fan Xiong,Liang Yang 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.5
In this work, the structural mechanisms of the cooling rate effect on the deformation behaviors in metallic glasses (MGs) isstudied, by performing the synchrotron radiation-based experiments coupled with a series of simulations. It is found that aMG prepared at lower cooling rate has the higher yield strength and is more likely to soften itself, resulting in lower plasticity.This is because some atomic-to-cluster level structural factors, such as coordination numbers, atomic packing efficiencies,cluster concentrations and regularities. In addition, a quantitative analysis reveals that higher cooling rate leads to more freevolumes, and significantly affect the evolution of free volumes during the compressive deformation, tuning the formationand the evolution of shear transformation zones, as well as the yield strength and the plasticity.
Minimal flavored U(1)′ for B -meson anomalies
Bian, Ligong,Choi, Soo-Min,Kang, Yoo-Jin,Lee, Hyun Min American Physical Society 2017 Physical Review D Vol.96 No.7
<P>We consider an anomaly free U(1)' model with favorable couplings to heavy flavors in the Standard Model ( SM), as motivated by B- meson anomalies at LHCb. Taking the U(1)' charge to be Q' = y(L mu - L tau) + x(B-3 - L-3), we can explain theB- meson anomalies without invoking extra charged fermions or flavor violation beyond the SM. We showthat there is a viable parameter space with a small x that is compatible with other meson decays, tau lepton, and neutrino experiments as well as theLHCdimuon searches. We briefly discuss the prospects of discovering the Z' gauge boson at the LHC in the proposed model.</P>
Bending and free vibration analysis of a smart functionally graded plate
Bian, Z.G.,Ying, J.,Chen, W.Q.,Ding, H.J. Techno-Press 2006 Structural Engineering and Mechanics, An Int'l Jou Vol.23 No.1
A simply supported hybrid plate consisting of top and bottom functionally graded elastic layers and an intermediate actuating or sensing homogeneous piezoelectric layer is investigated by an elasticity (piezoelasticity) method, which is based on state space formulations. The general spring layer model is adopted to consider the effect of bonding adhesives between the piezoelectric layer and the two functionally graded ones. The two functionally graded layers are inhomogeneous along the thickness direction, which are approached by laminate models. The effect of interlaminar bonding imperfections on the static bending and free vibration of the smart plate is discussed in the numerical examples.
Bian Nanyan,Chu Chenyu,Rung Shengan,Huangphattarakul Vicha,Huangphattarakul Vicha,Huangphattarakul Vicha,Hu Chen 한국조직공학과 재생의학회 2023 조직공학과 재생의학 Vol.20 No.1
After implantation of a biomaterial, both the host immune system and properties of the material determine the local immune response. Through triggering or modulating the local immune response, materials can be designed towards a desired direction of promoting tissue repair or regeneration. High-throughput sequencing technologies such as single-cell RNA sequencing (scRNA-seq) emerging as a powerful tool for dissecting the immune micro-environment around biomaterials, have not been fully utilized in the field of soft tissue regeneration. In this review, we first discussed the procedures of foreign body reaction in brief. Then, we summarized the influences that physical and chemical modulation of biomaterials have on cell behaviors in the micro-environment. Finally, we discussed the application of scRNA-seq in probing the scaffold immune micro-environment and provided some reference to designing immunomodulatory biomaterials. The foreign body response consists of a series of biological reactions. Immunomodulatory materials regulate immune cell activation and polarization, mediate divergent local immune micro-environments and possess different tissue engineering functions. The manipulation of physical and chemical properties of scaffolds can modulate local immune responses, resulting in different outcomes of fibrosis or tissue regeneration. With the advancement of technology, emerging techniques such as scRNA-seq provide an unprecedented understanding of immune cell heterogeneity and plasticity in a scaffold-induced immune micro-environment at high resolution. The in-depth understanding of the interaction between scaffolds and the host immune system helps to provide clues for the design of biomaterials to optimize regeneration and promote a pro-regenerative local immune micro-environment.
Bian, Yiying,An, Gwang-Jin,Kim, Keunyoung,Ngo, Thien,Shin, Sue,Bae, Ok-Nam,Lim, Kyung-Min,Chung, Jin-Ho Pergamon 2019 Food and Chemical Toxicology Vol. No.
<P><B>Abstract</B></P> <P>Ginseng and its active gradient, ginsenoside Rg3 (Rg3), are widely used for a variety of health benefits, but concerns over their misuses are increasing. Previously, it has been reported that Rg3 can cause hemolysis, but its health outcome remains unknown. Here, we demonstrated that Rg3 could promote the procoagulant activity of erythrocytes through the process of hemolysis, ultimately leading to increased thrombosis. In freshly isolated human erythrocytes, Rg3 caused pore formation and fragmentation of the erythrocyte membrane. Confocal microscopy observation and flow cytometric analysis revealed that remnant erythrocyte fragments after the exposure to Rg3 expressed phosphatidylserine (PS), which can promote blood coagulation through providing assembly sites for coagulation complexes. Rat <I>in vivo</I> experiments further confirmed that intravenous administration of Rg3 produced PS-bearing erythrocyte debris and increased thrombosis. Collectively, we demonstrated that Rg3 could induce the procoagulant activity of erythrocytes by generating PS-bearing erythrocyte debris through hemolysis, which might provoke thrombosis.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Ginsenoside Rg3, an active ingredient of ginseng, can induce PS bearing erythrocyte fragments through hemolysis. </LI> <LI> PS-bearing erythrocyte fragments resulting from Rg3 exposure can accelerate thrombin generation and increase adherence of erythrocytes to endothelial cells. </LI> <LI> Rg3 administration potentiated thrombus formation rat <I>in vivo.</I> </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Bian, Jing,Li, Bo,Kou, Xian-Juan,Liu, Tian-Zhou,Ming, Liang Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.11
Objective: To explore the predictive value of tumor markers, including cancer antigen 72-4 (CA72-4), cancer antigen 15-3 (CA15-3) and cancer antigen 125 (CA125), in single or combined detection, for the diagnosis of ovarian cancer. Methods: 120 patients diagnosed with ovarian cancer from August 2011 to March 2013 and 80 patients diagnosed with benign ovarian tumors were enrolled in this test, along with 50 health examination women randomly selected from the database as controls. Serum levels of CA72-4, CA15-3 and CA125 in this study were determined by electrochemiluminescence (ECL). Results: Serum levels of CA72-4, CA15-3 and CA125 in ovarian cancer were higher than those in healthy group and benign group (P<0.01).The sensitivity of combined detection of those three tumor markers for diagnosis of ovarian cancer was obviously higher than with single detection with each marker (P<0.01). Conclusions: CA72-4, CA15-3 and CA125 could be a good combination in the diagnosis of ovarian cancer. Patients whose tumor markers continue to increase should be highly suspected of malignancy.