Practice of Ethnobotanical Plants for the Treatment of Jaundice among Tharu Tribe of Far Western Nepal

( Pragya Bhatt ),( Madhusudan Subedi ),( Rajendra Dev Bhatt ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

Aims: Ethnomedicine is a system of therapy using natural agents and their derivatives to treat ailments by the ethnic communities. This study was aimed to analyze and record the knowledge of ethnomedicinal plants for treating liver disorders among tharu tribe of far western Nepal. Methods: A descriptive cross sectional observational study was conducted in ten Tharu Tribe inhabited villages of Kanchanpur district of Far West Nepal. Rapid Rural Appraisal (RRA), ‘Semi-structured interviews and focus group discussions were employed to collect data from four Guruwas, the main traditional healer, as key informants, some knowledgeable persons, (but not Guruwas) as informants and some youths in Tharu tribes, categorizing them into three groups. The information shared was further discussed among all three groups. Results: This study enumerated an encouraging data of 39 plant species being used for the treatment of liver and related diseases by tharu community. Out of these, 9 plant species (8 families) were solely used for jaundice and biliary ailments.33 other plant species were also recorded for being used to cure digestive system related disorders which might be related to liver diseases.Fresh plants and their parts including leaves (maximum used), barks, fruits, flowers, roots, rhizome and latex in the form of juice, powder, decoction, and paste and pulverized were used and administered by oral route. Some dietary restrictions (no alcohol, less oil etc.) were also made during medication. Consult the Guruwas for traditional healing was found to be the first choice for jaundice in the selected community. Around 43% jaundiced get well with traditional treatment while rest of the patients visited hospitals. Conclusions: A proper documentation and further elaborated research for ethnomedicinal plant being used by this tribal people is essential to understand the mechanism of action of these plants for jaundice and other liver diseases.

Conduction of Li+ cations in ethylene carbonate (EC) and propylene carbonate (PC): comparative studies using density functional theory

Bhatt, Mahesh Datt,Cho, Maenghyo,Cho, Kyeongjae Springer-Verlag 2012 Journal of solid state electrochemistry Vol.16 No.2

GENERALIZED UNITS: THE POINT-LIKE SETS

Bhatt, Piyush,Singh, Darshan Department of Mathematics 1982 Kyungpook mathematical journal Vol.22 No.1

Cytokine expression pattern in milk somatic cells of subclinical mastitis-affected cattle analyzed by real time PCR

Bhatt, Vaibhav D.,Khade, Prasad S.,Tarate, Sagar B.,Tripathi, Ajai K.,Nauriyal, Dev S.,Rank, Dharamshi N.,Kunjadia, Anju P.,Joshi, Chaitanya G. The Korean Society of Veterinary Science 2012 大韓獸醫學會誌 Vol.52 No.4

The expression profiles of inflammatory cytokines viz. interleukins (IL)-6, IL-8, IL-12, granulocyte macrophage-colony stimulating factor, interferon-${\gamma}$ and tumor necrosis factor-${\alpha}$ in response to subclinical mastitis in indigenous cattle breed Kankrej (n = 6), Gir (Bos indicus) (n = 12) and crossbred (Bos taurus${\times}$Bos indicus) (n = 7) were investigated using quantitative real time PCR. Significant correlation (p < 0.05) was observed between total bacterial load and somatic cell count (SCC) in all three breeds of cattle. All the cytokines were observed to be up-regulated compared to cows with healthy quarters, however, level of their expression varied among three breeds of cattle. In Kankrej most cytokines were found to be transcribed to higher levels than in other two breeds; the milk had higher load of bacteria but not so high SCC, implying that Kankrej has a higher inherent resistance against mastitis. The results of present study indicated that mammary glands of crossbred cattle are more sensitive to bacterial infection than indigenous breed of cattle as they elicit immune response at lower bacterial load and result into higher SCC. Research on identification of factors responsible for differentially expressed cytokines profiles and use of cytokines as immunomodulatory tools can pave way for formulating control strategies against bovine mastitis.

The Concepts of Buddha and Bodhisattva

Bhatt, S.R. International Association for Buddhist Thought & C 2002 International Journal of Buddhist Thought & Cultur Vol.1 No.-

The present paper attempts to deal with the concepts of Buddha and Bodhisattva as they are understood philosophically rather than historically, though historical perspective cannot be divorced from the philosophical one. Sakyamuni or Gautama, the Buddha, is at once both a historical figure and a body of ideas. It is only the latter which is taken into consideration here. Similarly there is no reference to any particular Bodhisattva revered in the tradition. The basic objective is to put forth those ideas and ideas and ideals and beliefs and practices for which the concepts of Buddha and Bodhisattva stand. Historically the Buddha and the Bodhisattva have lived by these ideas and ideals but the present paper only analysis the latter for pragmatic purpose so that they may be universalized and emulated in the contemporary times by strife-torn and violence-infected world. It specially focuses in the Karuna-centricity of these concepts correlation them with enhancment of quality of life and achievement of excellences. Mahakaruna or universal compassion is not just to be thought over or talked about but to be translated in action through proper and adequate endeavour (upaya kausala). Mahakaruna, therefore, must fructify in enhancement of quality of life and achievement of excellences (Paramitas).

UNIT-WISE SEPARATION POSTULATES

Bhatt, Piyush,Singh, Darshan Department of Mathematics 1982 Kyungpook mathematical journal Vol.22 No.2

Effect of doping on metal doped semiconductor

Bhatt Mahesh Datt,Shugo Suzuki,Takeaki Sakurai,Katsuhiro Akimoto 한국물리학회 2011 Current Applied Physics Vol.11 No.2

The effect of doping on position of interface states for metal doped bathocuproine (BCP) was studied with density functional theory (DFT). The doping of Ca atoms with BCP induces the formation of interface states with shift in their relative positions from Fermi level and approximately no shift in HOMO position of BCP molecule. The shift in the position of interface states towards higher binding energy was believed to be due to the presence of doping excess electrons from Ca at the interface. The analysis of modification in intensity of LUMO or EF or interface states, suggests the formation of multiply charged anions in heavily doped film. It clearly gives the direct evidence for the origin of the doping interface states in organic molecules. The effects of Ca doping on electrical properties were discussed.

Application of Response Surface Methodology and Plackett Burman Design assisted with Support Vector Machine for the Optimization of Nitrilase Production by Bacillus subtilis AGAB-2

Bhatt Ashish,Prajapati Darshankumar,Gupte Akshaya 한국미생물·생명공학회 2023 한국미생물·생명공학회지 Vol.51 No.1

Nitrilases are a hydrolase group of enzymes that catalyzes nitrile compounds and produce industrially important organic acids. The current objective is to optimize nitrilase production using statistical methods assisted with artificial intelligence (AI) tool from novel nitrile degrading isolate. A nitrile hydrolyzing bacteria Bacillus subtilis AGAB-2 (GenBank Ascension number- MW857547) was isolated from industrial effluent waste through an enrichment culture technique. The culture conditions were optimized by creating an orthogonal design with 7 variables to investigate the effect of the significant factors on nitrilase activity. On the basis of obtained data, an AI-driven support vector machine was used for the fitted regression, which yielded new sets of predicted responses with zero mean error and reduced root mean square error. The results of the above global optimization were regarded as the theoretical optimal function conditions. Nitrilase activity of 9832 ± 15.3 U/ml was obtained under optimized conditions, which is a 5.3-fold increase in compared to unoptimized (1822 ± 18.42 U/ml). The statistical optimization method involving Plackett Burman Design and Response surface methodology in combination with an AI tool created a better response prediction model with a significant improvement in enzyme production.

Nutrient Utilisation and Growth Performance of Broiler Rabbits Fed Oat Plant Meal and Tall Fescue Hay

Bhatt, R.S.,Sharma, S.R. Asian Australasian Association of Animal Productio 2001 Animal Bioscience Vol.14 No.9

Forty five Soviet Chinchilla rabbits weaned at 35 d of age were fed 5 experimental diets prepared by using oat plant meal ($T_2,\;T_4$) and tall fescue hay ($T_3,\;T_5$) at 25% and 50% level along with control ($T_1$). The gain in body weight at 84 d of age decreased with test material substitution, however, the differences were non significant when compared with oat plant meal and were significant (p<0.05) with tall fescue hay at both the levels. Feed conversion ratio also deteriorated with test material and its increasing proportion and the differences were significant (p<0.05). The performance-index calculated were 42.1, 36.7, 29.4, 33.3 and 18.8 in $T_1,\;T_2,\;T_3,\;T_4$ and $T_5$, respectively. Digestibility of all the organic nutrients decreased significantly (p<0.05) with test material incorporation, as a result nutritive value of the test diets decreased linearly. Nitrogen balance as per cent of intake was higher in oat plant meal substituted diet compared to tall fescue substituted diet. Cost per kg live weight gain was lowest with 50% oat plant meal followed by 25% oat plant meal incorporation. It was highest with tall fescue hay substitution. Nutritive value of oat plant meal as calculated was DCP 5.1%, TDN 35.8% and that of tall fescue hay was DCP 6.5%, TDN 30.8%. Thus, oat plant meal can be substituted safely up to 25% in the feeding regime of weaner rabbits whereas, for tall fescue hay the safe limit is below 25% level and needs to be ascertained.

Effect of Feed Protein Source on Digestion and Wool Production in Angora Rabbit

Bhatt, R.S.,Sawal, R.K.,Mahajan, A. Asian Australasian Association of Animal Productio 1999 Animal Bioscience Vol.12 No.7

Adult German cross $(German{\times}British{\times}Russian)$ angora rabbits (one year age), 32 in number were divided randomly into four groups $(T_1-T_4)$ with equal sex ratio and fed diets containing $T_1$ groundnut cake (GNC); $T_3$, soyaflakes (SF); $T_4$, sunflower cake (SFC) and $T_2$, a mixture of all the three cakes along with green forage as roughage for a period of 9 months. Nine per cent protein was added from each protein source. Fibre level was maintained by adjusting the level of rice phak in the diets. The diets were iso-nitrogenous and contained similar level of fibre. DMI through roughage was not affected due to source of protein in the diet, however, DMI through concentrate was higher $(p{\leq}0.05)$ with SFC diet, which resulted in higher total feed intake in the group $(T_4)$. Body weights increased up to second shearing, thereafter it decreased due to summer depression. Diet containing soyaflakes sustained higher wool yield whereas, it was lowest $(p{\leq}0.05)$ on SFC diet. Wool attributes (staple length, medullation, fibre diameter) were not affected due to source of protein in the diet. Digestibility of fibre and its fractions (ADF, cellulose, hemicellulose) decreased $(p{\leq}0.05)$ with incorporation of SFC in the diets. Balance of calcium was lowest whereas, that of nitrogen was highest with SFC diet $(T_4)$. Biological value of N and net protein utilization was better when different protein sources were mixed together $(T_2)$. Protein quality of soyaflakes proved better for wool production followed by groundnut cake and mixture of three protein sources. Sunflower cake alone or in combination decreased wool production which may be checked by supplementation of amino acids and energy.