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MBus : A Fully Synthesizable Low-power Portable Interconnect Bus for Millimeter-scale Sensor Systems
Inhee Lee,Ye-Sheng Kuo,Pat Pannuto,Gyouho Kim,Zhiyoong Foo,Ben Kempke,Seokhyeon Jeong,Yejoong Kim,Prabal Dutta,David Blaauw,Yoonmyung Lee 대한전자공학회 2016 Journal of semiconductor technology and science Vol.16 No.6
This paper presents a fully synthesizable low power interconnect bus for millimeter-scale wireless sensor nodes. A segmented ring bus topology minimizes the required chip real estate with low input/output pad count for ultra-small form factors. By avoiding the conventional open drain-based solution, the bus can be fully synthesizable. Low power is achieved by obviating a need for local oscillators in member nodes. Also, aggressive power gating allows low-power standby mode with only 53 gates powered on. An integrated wakeup scheme is compatible with a power management unit that has nW standby mode. A 3-module system including the bus is fabricated in a 180 nm process. The entire system consumes 8 nW in standby mode, and the bus achieves 17.5 pJ/bit/chip.
MBus: A Fully Synthesizable Low-power Portable Interconnect Bus for Millimeter-scale Sensor Systems
Lee, Inhee,Kuo, Ye-Sheng,Pannuto, Pat,Kim, Gyouho,Foo, Zhiyoong,Kempke, Ben,Jeong, Seokhyeon,Kim, Yejoong,Dutta, Prabal,Blaauw, David,Lee, Yoonmyung The Institute of Electronics and Information Engin 2016 Journal of semiconductor technology and science Vol.16 No.6
This paper presents a fully synthesizable low power interconnect bus for millimeter-scale wireless sensor nodes. A segmented ring bus topology minimizes the required chip real estate with low input/output pad count for ultra-small form factors. By avoiding the conventional open drain-based solution, the bus can be fully synthesizable. Low power is achieved by obviating a need for local oscillators in member nodes. Also, aggressive power gating allows low-power standby mode with only 53 gates powered on. An integrated wakeup scheme is compatible with a power management unit that has nW standby mode. A 3-module system including the bus is fabricated in a 180 nm process. The entire system consumes 8 nW in standby mode, and the bus achieves 17.5 pJ/bit/chip.
Metadynamic and Static Recrystallization Softening Behavior of a Bainite Steel
Lixin Li,Liangyu Zheng,Ben Ye,Zeqiong Tong 대한금속·재료학회 2018 METALS AND MATERIALS International Vol.24 No.1
The metadynamic recrystallization (MDRX) and static recrystallization (SRX) softening behavior of a bainitesteel was investigated by two-pass isothermal compression experiments at temperatures of 1173, 1273, 1373, and1473 K and strain rates of 0.01, 0.1, 1, and 10 s-1with inter-pass times of 1, 5, 10, and 30 s on a Gleeble-1500thermo-mechanical simulator. Kinetic equations were developed to evaluate the softening fractions caused byMDRX and SRX. A comparison between the experimental and predicted softening fractions showed that the proposedkinetic equations can provide a precise estimation of the MDRX and SRX behavior of the studied steel. Theresults based on the kinetic equations indicated that the MDRX and SRX softening fraction increases with theincrease in strain rate, deformation temperature, inter-pass time, and pre-strain; the activation energy of MDRX ismuch smaller than that of SRX; and the no-recrystallization temperature of the investigated steel is 1179.4 K.
Lixin Li,Sheng Liu,Ben Ye,Shengde Hu,Zhifeng Zhou 대한금속·재료학회 2016 METALS AND MATERIALS International Vol.22 No.3
A constitutive model including the kinetics of twinning and martensitic transformation has been established based on the dislocation theory and the mixture law. The stress-strain curve of a 304 stainless steel has been measured by a tensile test. The material constants for the constitutive model are then found through an inverse analysis of the stress-strain curve measured experimentally, determining the stress-strain relationship equation and the kinetics of twinning and martensitic transformation of the investigated alloy. The volume fractions of martensitic transformation have been measured by the magnetic tester of Fischer Model MP3C. It has been shown that the calculated stress-strain curve and the volume fractions of martensitic transformation are in agreement with those obtained from experimental measurements, demonstrating that the material constants found by using the stress-strain curve can capture the underlying materials science of deformation. On this basis, the influence of twins, martensitic transformation, and mechanical behavior of austenite and martensite on the strength and plasticity of the 304 stainless steel has been discussed further.
Talin-1 Correlates with Reduced Invasion and Migration in Human Hepatocellular Carcinoma Cells
Fang, Kun-Peng,Zhang, Jian-Lin,Ren, Yan-Hong,Qian, Ye-Ben Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.6
Background: Talin-1 is a cytoskeleton protein that participates in cell migration and plays a role in tumor formation, migration, and metastasis in different types of cancer. Chinese investigators have observed that the levels of Talin-1 protein and mRNA expression in HCC tissues are significantly lower than in the adjacent non-cancerous tissue. However, Japanese investigators have reported that Talin-1 is upregulated in HCC. Tln2 as homologous gene of Tln-1, which encodes a very similar protein, but the role of Talin-2 is very little known in primary liver cancer (PLC). We investigated whether the expression of Talin-1 in PLC may be associated with the histological subtype as well as the role of Talin-1 in tumor cell invasion and migration using human hepatocellular carcinoma cell lines. Materials and Methods: We measured the mRNA expression levels of Talin-1 and Talin-2 in five human liver cancer cell lines and normal human liver cell ($LO_2$ cell line) by real-time PCR and the protein expression levels of Talin-1 by Western blot. Migration and invasion of the cells were assessed using transwell assays and cell scratch experiments, respectively, and proliferation was assessed by soft AGAR colony formation. Results: Talin-1 and Talin-2 expression differed significantly between the five human liver cancer cell lines and $LO_2$ cell line (p<0.05). Compared with the $LO_2$ cell line, the invasion and migration capabilities of the five cancer cell lines differed significantly (p<0.05). Similarly, the colony-forming ability differed (p<0.05). Conclusions: High levels of Talin-1 expression are correlated with reduced invasion and migration as well as decreased malignancy in human liver cancer cell lines; the suppression of Talin-1 promotes invasion and migration. In addition, Talin-2 may be correlated with invasion and migration in human hepatocellular carcinoma.
Guo, Yan-Wu,Guo, Hui-Li,Li, Xing,Huang, Li-Li,Zhang, Bo-Ning,Pang, Xiao-Bin,Liu, Ben-Ye,Ma, Lan-Qing,Wang, Hong 한국식물생명공학회 2013 Plant biotechnology reports Vol.7 No.3
In our recent work (Ma et al., in Planta 229(3):457-469, 2009a and 229(4):1077-1086, 2009b), two three-intron type III PKS genes, PcPKS1 and PcPKS2, were isolated from Polygonum cuspidatum Sieb. et Zucc. Phylogenetic and functional analyses revealed PcPKS1 is a three-intron chalcone synthase (CHS) gene, and PcPKS2 is found to be a three-intron benzalacetone synthase (BAS) gene. The regular CHS encoded by a single intron gene have not been isolated and characterized from P. cuspidatum. In this work a further CHS with one intron (PcPKS3) and a stilbene synthase (STS) gene with three-intron (PcPKS5) were isolated and characterized by functional and phylogenetic analyses. In comparison with PcPKS1, a bifunctional enzyme with both CHS and BAS activity, the enzymatic product of recombinant PcPKS3 was naringenin, bis-noryangonin (BNY) and 4-coumaroyltriacetic acid lactone (CTAL) occurred as side products. The PcPKS5 synthesized resveratrol and a trace amount of naringenin from p-coumaroyl-CoA. To our knowledge, PcPKS5 is the first reported three-intron STS gene in flowering plants. In this work, we speculated that this involved a possible evolutionary route of plant-specific type III PKS superfamily in P. cuspidatum.
Lan-Qing Ma,Yan-Wu Guo,Hui-Li Guo,Xing Li,Li-Li Huang,Bo-Ning Zhang,Xiao-Bin Pang,Ben-Ye Liu,Hong Wang 한국식물생명공학회 2013 Plant biotechnology reports Vol.7 No.3
In our recent work (Ma et al., in Planta229(3):457–469, 2009a and 229(4):1077–1086, 2009b),two three-intron type III PKS genes, PcPKS1 and PcPKS2,were isolated from Polygonum cuspidatum Sieb. et Zucc. Phylogenetic and functional analyses revealed PcPKS1 is athree-intron chalcone synthase (CHS) gene, and PcPKS2 isfound to be a three-intron benzalacetone synthase (BAS)gene. The regular CHS encoded by a single intron genehave not been isolated and characterized from P. cuspidatum. In this work a further CHS with one intron (PcPKS3)and a stilbene synthase (STS) gene with three-intron(PcPKS5) were isolated and characterized by functionaland phylogenetic analyses. In comparison with PcPKS1, abifunctional enzyme with both CHS and BAS activity, theenzymatic product of recombinant PcPKS3 was naringenin,bis-noryangonin (BNY) and 4-coumaroyltriacetic acidlactone (CTAL) occurred as side products. The PcPKS5synthesized resveratrol and a trace amount of naringeninfrom p-coumaroyl-CoA. To our knowledge, PcPKS5 is thefirst reported three-intron STS gene in flowering plants. Inthis work, we speculated that this involved a possibleevolutionary route of plant-specific type III PKS superfamilyin P. cuspidatum.