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      • On-line Rock Fragment Delineation on Simple Thresholding with Fuzzy Comprehensive Evaluation

        Wang Weixing,Liang Yanjie,Liao Yipeng,Bai Lina 보안공학연구지원센터 2015 International Journal of Hybrid Information Techno Vol.8 No.6

        The classification and measurement of rock fragments is very important in mining and construction engineering. The monitoring system acquires and analyses the fragment images from a gravitational falling stream at the end of a moving conveyor belt, and the key function of the system is to construct an image segmentation algorithm. To achieve this goal, an adaptive thresholding algorithm with fuzzy comprehensive evaluation is proposed. Firstly, a grabbed image is roughly segmented by using a global auto-thresholding algorithm. Then each of the objects is measured and analyzed if it includes the multiple fragments touching each other, based on the fuzzy comprehensive evaluation method in which the salient fragment features of area, perimeter, shape, gradient magnitude and gray-level flatness are extracted, and for each of the features, the membership function is constructed experimentally. Finally, each of the touching fragment regions, as one image, is auto-thresholded again, and this procedure is repeated until no region can be further separated. The experimental results show that compared to cluster analysis, graph based, and FCM image segmentation algorithms the new algorithm can make image segmentation well for the falling fragments on-line.

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        Xylazole inhibits NO-cGMP pathway in fetal rat nerve cells

        Xinyu Wang,Yue Wu,Lin Liu,Hui Bai,Zhiheng Zhang,Mingchao Zhao,Tianwen Ma,Xiaopeng Song,Lina Jia,Liangyu Lv,Yue Yu,Xinyu Xu,Hong Chen,Li Gao 대한수의학회 2022 Journal of Veterinary Science Vol.23 No.1

        Background: Xylazole (Xyl) is a veterinary anesthetic that is structurally and functionally similar to xylazine. However, the effects of Xyl in vitro remain unknown. Objectives: This study aimed to investigate the anesthetic mechanism of Xyl using fetal rat nerve cells treated with Xyl. Methods: Fetal rat nerve cells cultured for seven days were treated with 10, 20, 30, and 40 μg/ mL Xyl for 0, 5, 10, 15, 20, 25, 30, 45, 60, 90, and 120 min. Variations of amino acid neurotransmitters (AANTs), Nitric oxide-Cyclic GMP (NO-cGMP) signaling pathway, and ATPase were evaluated. Results: Xyl decreased the levels of cGMP and NO in nerve cells. Furthermore, Xyl affected the AANT content and Na+-K+-ATPase and Ca2+-Mg2+-ATPase activity in nerve cells. These findings suggested that Xyl inhibited the NO-cGMP signaling pathway in nerve cells in vitro. Conclusions: This study provided new evidence that the anesthetic and analgesic effects of Xyl are related to the inhibition of the NO-cGMP signaling pathway.

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