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      • SCISCIESCOPUS

        Collimation, Acceleration, and Recollimation Shock in the Jet of Gamma-Ray Emitting Radio-loud Narrow-line Seyfert 1 Galaxy 1H0323+342

        Hada, Kazuhiro,Doi, Akihiro,Wajima, Kiyoaki,D’Ammando, Filippo,Orienti, Monica,Giroletti, Marcello,Giovannini, Gabriele,Nakamura, Masanori,Asada, Keiichi American Astronomical Society 2018 The Astrophysical journal Vol.860 No.2

        <P>We investigated the detailed radio structure of the jet of 1H 0323+342 using high-resolution multifrequency Very Long Baseline Array observations. This source is known as the nearest gamma-ray emitting radio-loud narrow-line Seyfert 1 (NLS1) galaxy. We discovered that the morphology of the inner jet is well characterized by a parabolic shape, indicating that the jet is continuously collimated near the jet base. On the other hand, we found that the jet expands more rapidly at larger scales, resulting in a conical shape. The location of the 'collimation break' is coincident with a bright quasi-stationary feature at mas from core (corresponding to a deprojected distance on the order of similar to 100 pc), where the jet width locally contracts together with highly polarized signals, suggesting a recollimation shock. We found that the collimation region is coincident with the region where the jet speed gradually accelerates, suggesting a coexistence of the jet acceleration and collimation zone, ending up with the recollimation shock, which could be a potential site of high-energy 7-ray flares detected by the Fermi-LAT. Remarkably, these observational features of the 1H 0323+342 jet are overall very similar to those of the nearby radio galaxy M87 and HST-1 as well as some blazars, suggesting that a common jet formation mechanism might be at work. Based on the similarity of the jet profile of the two sources, we also briefly discuss the mass of the central black hole of 1H 0323+342, which is also still highly controversial in this source and NLS in general.</P>

      • KCI등재후보

        Usefulness of Colored 3D Imaging of Respiratory Impedance in Asthma

        Toshihiro Shirai,Kazutaka Mori,Masashi Mikamo,Yuichiro Shishido,Takefumi Akita,Satoru Morita,Kazuhiro Asada,Masato Fujii,Takafumi Suda,Kingo Chida 대한천식알레르기학회 2013 Allergy, Asthma & Immunology Research Vol.5 No.5

        Purpose: Recently, the clinical application of the forced oscillation technique (FOT) has progressed with the spread of commercially available FOT devices, including the impulse oscillation system and MostGraph. We investigated the usefulness of color 3D imaging of respiratory impedance in asthma using MostGraph. Methods: Whole-breath and within-breath respiratory system resistance (Rrs) and reactance (Xrs) were measured in 78 patients with asthma. Color 3D images were classified into three patterns: the chronic obstructive pulmonary disease (COPD)-like pattern (high values of Rrs and Xrs with a marked respiratory cycle and frequency dependence), the asthma pattern (moderately high Rrs over the entire frequency and a respiratory cycle with slight Xrs changes), and a normal-like pattern (low Rrs and Xrs with few within-breath changes). The classification was performed by three researchers, who were unaware of the clinical information, and the clinical characteristics were compared among the three groups. Results: Color 3D imaging provided a COPD-like pattern in 25 patients, an asthma pattern in 39 patients, and a normal-like pattern in 14 patients. Patients with the COPD-like pattern were predominantly female with a higher body mass index, lower forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC), and higher Rrs and Xrs values (whole-breath and within-breath variation). Those with the normal pattern had higher FEV1 and FVC, and a lower single-breath nitrogen washout slope. There were no differences in asthma control or exhaled nitric oxide levels among the three groups. Conclusions: These results suggest that color 3D imaging of respiratory impedance may show asthma phenotypes.

      • KCI등재

        Mucus Plugs and Small Airway Dysfunction in Asthma, COPD, and Asthma-COPD Overlap

        Tamura Kanami,Shirai Toshihiro,Hirai Keita,Nakayasu Hiromasa,Takahashi Shingo,Kishimoto Yutaro,Akamatsu Taisuke,Asada Kazuhiro,Kato Satoshi 대한천식알레르기학회 2022 Allergy, Asthma & Immunology Research Vol.14 No.2

        Purpose: There are reports concerning mucus plugs detected on high-resolution computed tomography images and airflow obstruction in asthma and chronic obstructive pulmonary disease (COPD). However, little is known about the associations between mucus plugs and small airway dysfunction (SAD). We evaluated the relationship between mucus plugs and pulmonary function in patients with asthma, COPD, and asthma-COPD overlap (ACO), and investigated the relevance to SAD and type 2 inflammation in a retrospective study. Methods: Subjects included 49 asthmatic, 40 ACO, and 41 COPD patients. ACO was diagnosed based on the Japanese Respiratory Society ACO guidelines. Clinical and laboratory parameters, including blood eosinophil count, serum total IgE levels, fractional exhaled nitric oxide (FeNO), spirometry, and forced oscillation technique (FOT), were compared between patients with and without mucus plugs. Results: Mucus plugs were found in 29 (59%) asthmatic, 25 (65%) ACO, 17 (41%) COPD patients. Patients with mucus plugs had reduced spirometry and larger FOT parameters, especially in COPD patients. Mucus scores correlated positively with IgE in ACO and FeNO in asthmatic patients, but not in COPD patients. Multivariate logistic regression analysis revealed that SAD parameters, including forced vital capacity and resonant frequency, a respiratory reactance parameter, were significantly associated with the presence of mucus plugs in the whole studied population. Conclusions: SAD, rather than large airway dysfunction, was associated with mucus plugs in asthma, ACO, and COPD patients.

      • SCISCIESCOPUS

        230 GHz VLBI OBSERVATIONS OF M87: EVENT‐HORIZON‐SCALE STRUCTURE DURING AN ENHANCED VERY‐HIGH‐ENERGY $\gamma $‐RAY STATE IN 2012

        Akiyama, Kazunori,Lu, Ru-Sen,Fish, Vincent L.,Doeleman, Sheperd S.,Broderick, Avery E.,Dexter, Jason,Hada, Kazuhiro,Kino, Motoki,Nagai, Hiroshi,Honma, Mareki,Johnson, Michael D.,Algaba, Juan C.,Asada, IOP Publishing 2015 The Astrophysical journal Vol.807 No.2

        <P>We report on 230 GHz (1.3 mm) very long baseline interferometry (VLBI) observations of M87 with the Event Horizon Telescope using antennas on Mauna Kea in Hawaii, Mt. Graham in Arizona, and Cedar Flat in California. For the first time, we have acquired 230 GHz VLBI interferometric phase information on M87 through measurement of the closure phase on the triangle of long baselines. Most of the measured closure phases are consistent with 0 degrees as expected by physically motivated models for 230 GHz structure such as jet models and accretion disk models. The brightness temperature of the event-horizon-scale structure is similar to 1 x 10(10) K derived from the compact flux density of similar to 1 Jy and the angular size of similar to 40 mu as similar to 5.5 R-s, which is broadly consistent with the peak brightness of the radio cores at 1-86 GHz located within similar to 10(2) R-s. Our observations occurred in the middle of an enhancement in very-high-energy (VHE) gamma-ray flux, presumably originating in the vicinity of the central black hole. Our measurements, combined with results of multi-wavelength observations, favor a scenario in which the VHE region has an extended size of similar to 20-60 R-s.</P>

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