SPIF-A: on the development of a new concept of incremental forming machine

Alves de Sousa, R.J.,Ferreira, J.A.F.,Sa de Farias, J.B.,Torrao, J.N.D.,Afonso, D.G.,Martins, M.A.B.E. Techno-Press 2014 Structural Engineering and Mechanics, An Int'l Jou Vol.49 No.5

This paper presents the design and project of an innovative concept for a Single Point Incremental Forming (SPIF) Machine. Nowadays, equipment currently available for conducting SPIF result mostly from the adaptation of conventional CNC machine tools that results in a limited range of applications in terms of materials and geometries. There is also a limited market supply of equipment dedicated to Incremental Sheet Forming (ISF), that are costly considering low batches, making it unattractive for industry. Other factors impairing a quicker spread of SPIF are large forming times and poor geometrical accuracy of parts. The following sections will depict the development of a new equipment, designed to overcome some of the limitations of machines currently used, allowing the development of a sounding basis for further studies on the particular features of this process. The equipment here described possesses six-degrees-of freedom for the tool, for the sake of improved flexibility in terms of achievable tool-paths and an extra stiffness provided by a parallel kinematics scheme. A brief state of the art about the existing SPIF machines is provided to support the project's guidelines.

Nonlinear mixed models for characterization of growth trajectory of New Zealand rabbits raised in tropical climate

de Sousa, Vanusa Castro,Biagiotti, Daniel,Sarmento, Jose Lindenberg Rocha,Sena, Luciano Silva,Barroso, Priscila Alves,Barjud, Sued Felipe Lacerda,de Sousa Almeida, Marisa Karen,da Silva Santos, Natana Asian Australasian Association of Animal Productio 2022 Animal Bioscience Vol.35 No.5

Objective: The identification of nonlinear mixed models that describe the growth trajectory of New Zealand rabbits was performed based on weight records and carcass measures obtained using ultrasonography. Methods: Phenotypic records of body weight (BW) and loin eye area (LEA) were collected from 66 animals raised in a didactic-productive module of cuniculture located in the southern Piaui state, Brazil. The following nonlinear models were tested considering fixed parameters: Brody, Gompertz, Logistic, Richards, Meloun 1, modified Michaelis-Menten, Santana, and von Bertalanffy. The coefficient of determination (R²), mean squared error, percentage of convergence of each model (%C), mean absolute deviation of residuals, Akaike information criterion (AIC), and Bayesian information criterion (BIC) were used to determine the best model. The model that best described the growth trajectory for each trait was also used under the context of mixed models, considering two parameters that admit biological interpretation (A and k) with random effects. Results: The von Bertalanffy model was the best fitting model for BW according to the highest value of R² (0.98) and lowest values of AIC (6,675.30) and BIC (6,691.90). For LEA, the Logistic model was the most appropriate due to the results of R² (0.52), AIC (783.90), and BIC (798.40) obtained using this model. The absolute growth rates estimated using the von Bertalanffy and Logistic models for BW and LEA were 21.51g/d and 3.16 cm², respectively. The relative growth rates at the inflection point were 0.028 for BW (von Bertalanffy) and 0.014 for LEA (Logistic). Conclusion: The von Bertalanffy and Logistic models with random effect at the asymptotic weight are recommended for analysis of ponderal and carcass growth trajectories in New Zealand rabbits. The inclusion of random effects in the asymptotic weight and maturity rate improves the quality of fit in comparison to fixed models.

Pharmacological Treatment of Acute Unilateral Vestibulopathy: A Review

Sousa Francisco Alves de,Alves Clara Serdoura,Pinto Ana Nóbrega,Meireles Luís,Rego Ângela Reis 대한청각학회 2024 Journal of Audiology & Otology Vol.28 No.1

There have been few investigations on the epidemiology, etiology, and medical management of acute unilateral vestibulopathy (AUV). Short-term pharmaceutical resolutions include vestibular symptomatic suppressants, anti-emetics, and some cause-based therapies. Anticholinergics, phenothiazines, antihistamines, antidopaminergics, benzodiazepines, and calcium channel antagonists are examples of vestibular suppressants. Some of these medications may show their effects through multiple mechanisms. In contrast, N-acetyl-L-leucine, Ginkgo biloba, and betahistine improve central vestibular compensation. Currently, AUV pathophysiology is poorly understood. Diverse hypotheses have previously been identified which have brought about some causal treatments presently used. According to some publications, acute administration of anti-inflammatory medications may have a deleterious impact on both post-lesional functional recovery and endogenous adaptive plasticity processes. Thus, some authors do not recommend the use of corticosteroids in AUV. Antivirals are even more contentious in the context of AUV treatment. Although vascular theories have been presented, no verified investigations employing anti-clotting or vasodilator medications have been conducted. There are no standardized treatment protocols for AUV to date, and the pharmacological treatment of AUV is still questionable. This review addresses the most current developments and controversies in AUV medical treatment.

Quantitative assessment of image artifacts from root filling materials on CBCT scans made using several exposure parameters

Katharina Alves Rabelo,Yuri Wanderley Cavalcanti,Martina Gerlane de Oliveira Pinto,Saulo Leonardo Sousa Melo,Paulo Sérgio Flores Campos,Luciana Soares de Andrade Freitas Oliveira,Daniela Pita de Melo 대한영상치의학회 2017 Imaging Science in Dentistry Vol.47 No.3

Purpose: To quantify artifacts from different root filling materials in cone-beam computed tomography (CBCT) images acquired using different exposure parameters. Materials and Methods: Fifteen single-rooted teeth were scanned using 8 different exposure protocols with 3 different filling materials and once without filling material as a control group. Artifact quantification was performed by a trained observer who made measurements in the central axial slice of all acquired images in a fixed region of interest using ImageJ. Hyperdense artifacts, hypodense artifacts, and the remaining tooth area were identified, and the percentages of hyperdense and hypodense artifacts, remaining tooth area, and tooth area affected by the artifacts were calculated. Artifacts were analyzed qualitatively by 2 observers using the following scores: absence (0), moderate presence (1), and high presence (2) for hypodense halos, hypodense lines, and hyperdense lines. Two-way ANOVA and the post-hoc Tukey test were used for quantitative and qualitative artifact analysis. The Dunnet test was also used for qualitative analysis. The significance level was set at P<.05. Results: There were no significant interactions among the exposure parameters in the quantitative or qualitative analysis. Significant differences were observed among the studied filling materials in all quantitative analyses. In the qualitative analyses, all materials differed from the control group in terms of hypodense and hyperdense lines (P<.05). Fiberglass posts did not differ statistically from the control group in terms of hypodense halos (P>.05). Conclusion: Different exposure parameters did not affect the objective or subjective observations of artifacts in CBCT images; however, the filling materials used in endodontic restorations did affect both types of assessments.

Basic Human Needs in the Elderly Receiving Palliative Care: A Scoping Review

Thaciane Alves Mota,Manuela Bastos Alves,Ailton de Oliveira Dantas,Erica Brandão de Moraes,Anderson Reis de Sousa,Rudval Souza da Silva 한국호스피스완화의료학회 2022 한국호스피스.완화의료학회지 Vol.25 No.4

Purpose: This scoping review identified scientific evidence on basic human needs (BHNs) in the elderly receiving palliative care. Methods: Systematic searches were conducted using six electronic databases (PubMed, CINAHL, Scopus, Lilacs, IBECS, and Web of Science). The initial search resulted in 1,227 articles, of which 104 were identified as potentially relevant. Fifty-three articles that met the inclusion criteria were identified and included in the final analysis. Results: Using the three hierarchical dimensions of the BHN model, 17 needs were organised, with five in the psychobiological dimension, 10 in the psychosocial dimension, and two in the psychospiritual dimension. These needs reflect the importance of care with dignity and relief from suffering for the elderly in palliative care. Conclusion: Recognising impaired BHNs in elderly people receiving palliative care will contribute to better care plans for the elderly, considering the multiple bio-psycho-social-spiritual dimensions of BHNs. This review points to a predominance of psychosocial needs.

Pneumoretroperitoneum and Sepsis After Transanal Endoscopic Resection of a Rectal Lateral Spreading Tumor

Bruno Augusto Alves Martins,Marcelo de Melo Andrade Coura,Romulo Medeiros de Almeida,Natascha Mourão Moreira,João Batista de Sousa,Paulo Gonçalves de Oliveira 대한대장항문학회 2017 Annals of Coloproctolgy Vol.33 No.3

Transanal endoscopic microsurgery is considered a safe, appropriate, and minimally invasive approach, and complications after endoscopic microsurgery are rare. We report a case of sepsis and pneumoretroperitoneum after resection of a rectal lateral spreading tumor. The patient presented with rectal mucous discharge. Colonoscopy revealed a rectal lateral spreading tumor. The patient underwent an endoscopic transanal resection of the lesion. He presented with sepsis of the abdominal focus, and imaging tests revealed pneumoretroperitoneum. A new surgical intervention was performed with a loop colostomy. Despite the existence of other reports on pneumoretroperitoneum after transanal endoscopic microsurgery, what draws attention to this case is the association with sepsis.

Quantitative assessment of image artifacts from root filling materials on CBCT scans made using several exposure parameters

Rabelo, Katharina Alves,Cavalcanti, Yuri Wanderley,de Oliveira Pinto, Martina Gerlane,Melo, Saulo Leonardo Sousa,Campos, Paulo Sergio Flores,de Andrade Freitas Oliveira, Luciana Soares,de Melo, Daniel Korean Academy of Oral and Maxillofacial Radiology 2017 Imaging Science in Dentistry Vol.47 No.3

Purpose: To quantify artifacts from different root filling materials in cone-beam computed tomography (CBCT) images acquired using different exposure parameters. Materials and Methods: Fifteen single-rooted teeth were scanned using 8 different exposure protocols with 3 different filling materials and once without filling material as a control group. Artifact quantification was performed by a trained observer who made measurements in the central axial slice of all acquired images in a fixed region of interest using ImageJ. Hyperdense artifacts, hypodense artifacts, and the remaining tooth area were identified, and the percentages of hyperdense and hypodense artifacts, remaining tooth area, and tooth area affected by the artifacts were calculated. Artifacts were analyzed qualitatively by 2 observers using the following scores: absence (0), moderate presence (1), and high presence (2) for hypodense halos, hypodense lines, and hyperdense lines. Two-way ANOVA and the post-hoc Tukey test were used for quantitative and qualitative artifact analysis. The Dunnet test was also used for qualitative analysis. The significance level was set at P<.05. Results: There were no significant interactions among the exposure parameters in the quantitative or qualitative analysis. Significant differences were observed among the studied filling materials in all quantitative analyses. In the qualitative analyses, all materials differed from the control group in terms of hypodense and hyperdense lines (P<.05). Fiberglass posts did not differ statistically from the control group in terms of hypodense halos(P>.05). Conclusion: Different exposure parameters did not affect the objective or subjective observations of artifacts in CBCT images; however, the filling materials used in endodontic restorations did affect both types of assessments.

SPIF-A: on the development of a new concept of incremental forming machine

R.J. Alves de Sousa,J.A.F. Ferreira,J.B. Sá de Farias,J.N.D. Torrão,D.G. Afonso,M.A.B.E Martins 국제구조공학회 2014 Structural Engineering and Mechanics, An Int'l Jou Vol.49 No.5

This paper presents the design and project of an innovative concept for a Single PointIncremental Forming (SPIF) Machine. Nowadays, equipment currently available for conducting SPIF resultmostly from the adaptation of conventional CNC machine tools that results in a limited range of applicationsin terms of materials and geometries. There is also a limited market supply of equipment dedicated toIncremental Sheet Forming (ISF), that are costly considering low batches, making it unattractive forindustry. Other factors impairing a quicker spread of SPIF are large forming times and poor geometricalaccuracy of parts. The following sections will depict the development of a new equipment, designed toovercome some of the limitations of machines currently used, allowing the development of a sounding basisfor further studies on the particular features of this process. The equipment here described possesses sixdegrees-of freedom for the tool, for the sake of improved flexibility in terms of achievable tool-paths and anextra stiffness provided by a parallel kinematics scheme. A brief state of the art about the existing SPIFmachines is provided to support the project’s guidelines.

Trametes villosa Lignin Peroxidase (TvLiP): Genetic and Molecular Characterization

( Rita Terezinha De Oliveira Carneiro ),( Maiza Alves Lopes ),( Marilia Lordelo Cardoso Silva ),( Veronica Da Silva Santos ),( Volnei Brito De Souza ),( Aurizangela Oliveira De Sousa ),( Carlos Primin 한국미생물 · 생명공학회 2017 Journal of microbiology and biotechnology Vol.27 No.1

White-rot basidiomycetes are the organisms that decompose lignin most efficiently, and Trametes villosa is a promising species for ligninolytic enzyme production. There are several publications on T. villosa applications for lignin degradation regarding the expression and secretion of laccase and manganese peroxidase (MnP) but no reports on the identification and characterization of lignin peroxidase (LiP), a relevant enzyme for the efficient breakdown of lignin. The object of this study was to identify and partially characterize, for the first time, gDNA, mRNA, and the corresponding lignin peroxidase (TvLiP) protein from T. villosa strain CCMB561 from the Brazilian semiarid region. The presence of ligninolytic enzymes produced by this strain grown in inducer media was qualitatively and quantitatively analyzed by spectrophotometry, qPCR, and dye fading using Remazol Brilliant Blue R. The spectrophotometric analysis showed that LiP activity was higher than that of MnP. The greatest LiP expression as measured by qPCR occurred on the 7^th day, and the ABSA medium (agar, sugarcane bagasse, and ammonium sulfate) was the best that favored LiP expression. The amplification of the TvLiP gene median region covering approximately 50% of the T. versicolor LPGIV gene (87% identity); the presence of Trp199, Leu115, Asp193, Trp199, and Ala203 in the translated amplicon of the T. villosa mRNA; and the close phylogenetic relationship between TvLiP and T. versicolor LiP all indicate that the target enzyme is a lignin peroxidase. Therefore, T. villosa CCMB561 has great potential for use as a LiP, MnP, and Lac producer for industrial applications.

Microtensile bond strength of silorane-based composite specific adhesive system using different bonding strategies

Laura Alves Bastos,Ana Beatriz Silva Sousa,Brahim Drubi-Filho,Fernanda de Carvalho Panzeri Pires-de-Souza,Lucas da Fonseca Roberti Garcia 대한치과보존학회 2015 Restorative Dentistry & Endodontics Vol.40 No.1

Objectives: The aim of this study was to evaluate the effect of pre-etching on the bond strength of silorane-based composite specific adhesive system to dentin. Materials and Methods: Thirty human molars were randomly divided into 5 groups according to the different bonding strategies. For teeth restored with silorane-based composite (Filtek Silorane, 3M ESPE), the specific self-etching adhesive system (Adhesive System P90, 3M ESPE) was used with and without pre-etching (Pre-etching/Silorane and Silorane groups). Teeth restored with methacrylate based-composite (Filtek Z250, 3M ESPE) were hybridized with the two-step self-etching system (Clearfil SE Bond, Kuraray), with and without pre-etching (Pre-etching/Methacrylate and Methacrylate groups), or three-step adhesive system (Adper Scotchbond Multi-Purpose, 3M ESPE) (Three-step/ Methacrylate group) (n = 6). The restored teeth were sectioned into stick-shaped test specimens (1.0 x 1.0 mm), and coupled to a universal test machine (0.5 mm/min) to perform microtensile testing. Results: Pre-etching/Methacrylate group presented the highest bond strength values, with significant difference from Silorane and Three-step/ Methacrylate groups (p < 0.05). However, it was not significantly different from Preetching/ Silorane and Methacrylate groups. Conclusions: Pre-etching increased bond strength of silorane-based composite specific adhesive system to dentin