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      • KCI등재

        조선후기의 忠淸兵營

        李康吉(Lee Kang-Gil) 역사실학회 2004 역사와실학 Vol.27 No.-

        This thesis is to define the systems of the Chungcheong Provincial Army which have been relatively neglected in the study of the late period of the Joseon Dynasty. Recently, the study of the Army system of the late period of the Joseon Dynasty has been focused chiefly on the study of the central army. This is because the local magistrates had escaped before the king sought shelter during the Japanese invasion(壬辰倭亂) in Korea during 1592. The support of government to the local army was very poor because the peaceful period had been continuous for a long time. The upbringing of the local army which was mainly for protection against foreign invasion was neglected too. In the past, the study of the local anny was relatively poor, but nowadays studies of regional history are beginning to appear, and more study is now being carried out. However, despite of the studied accomplishment of the late period of the Joseon Dynasty military system, the study of the Chungcheong Army is still, overall very poor. Even though there are some accomplishments in this field, most of all these had been carried out in brief. To meet the recent study trend, this thesis is to deal with the Chungcheong Army Headquarters during the late period of the Ioseon Dynasty, a field which has not been developed yet. The Headquarters of the Chungcheong Army was original1y located in Haemi(海美) near the West Sea(西海) for defense of Japanese pirates(倭寇). After the Japanese invasion(壬辰倭亂) and Ch’ing(丙子胡亂), the importance of Cheongju(淸州) was emphasized as it was strategic post located at the intersection of Hoseo(湖西) and Youngnahm(嶺南) areas. As such the Headquarters moved to Cheongju(淸州) as it was judged advantageous for protecting the Capital from rebellion Accordingly, the official rank (poomgy e : 品階) of the Chungcheong army's supreme commander was raised and Sangdangsanseong(相黨山城) was attached to complement the Army. In the 41st year of Youngjo’s(英祖) reign, the total number of Chungcheong provincial soldiers was increased about 20,000 soldiers more than that of 20 years before. So the burden of the military duty was increased too. Due to this, a lot of abuse of the people's duty took place. In this study, chronicles such as Joseonwangjosillok(朝鮮王朝實錄), Bibyeonsadeungrok(備邊司謄錄), and Seungjeongwonilgi(承政院日記), the town magazine including Sejongsillokjiriji(世宗實錄地理志), and the books which are preserved in Kyujanggak(奎章閣) are to be examined. The establishment, the structure, the formation, and the functional realities of the Chungcheong Army are to be dealt with based upon the military system of the J oseon dynasty and related studies. This thesis is to analyze how the Chungcheong Provincial Army developed according to the political chaoses and economic changes. In the future, more and more historical materials should be revealed ; the case study of the local army system of the late period of Joseon dynasty should be continued ; and the work should achieve progress.

      • KCI등재

        골쇄보가 Streptomycin으로 손상된 생쥐의 배양 섬유모세포에 미치는 영향

        박상면 ( Sang Myeon Park ),이종화 ( Joung Hwa Lee ),이강창 ( Kang Chang Lee ),양현웅 ( Hyun Woong Yang ),이병찬 ( Byung Chan Lee ),이정헌 ( Jung Hun Lee ),정종 ( Jong Gil Jeong ),서부일 ( Bu Il Seo ),강영성 ( Young Seung Kang 대한본초학회 2003 大韓本草學會誌 Vol.18 No.1

        N/A Objectives : To examine the cytotoxicity of streptomycin(STR) on cultured mouse fibroblasts, cytotoxocity-induced by STR was measured by MTT assay. Methods : Fibroblasts were cultured in the media containing various concentrations of STR for 72 hours. In addition, cytoprotective effect of Drynariase Rhizoma(DR) on STR-induced cytotoxicity in fibroblasts was examined when fibroblasts were preincubated with various concentrations of DR for 2 hours before treatment of 5 ㎍/ml STR for 72 hours. Results : STR decreased remarkably cell viability in a dependentmanner in these cultures, and also DR increased cell viability and amount of DNA synthesis damaged by STR. Conclusions : From the above results, it is suggested that STR has toxic effect in cultured mouse fibroblasts, and also DR was effective in the protection of STR-induced cytotoxicity in these cultures.

      • KCI등재

        동과자가 Glucose Oxidase로 손상된 혈관내피세포에 미치는 영향

        서은아 ( Eun A Seo ),최승석 ( Natthew Seung Suk Choi ),이병찬 ( Byung Chan Lee ),이재규 ( Jai Kyoo Lee ),이강창 ( Kang Chang Lee ),정종 ( Jong Gil Jeong ),신민교 ( Min Kyu Shin ),송호준 ( Ho Joon Song ) 대한본초학회 2003 大韓本草學會誌 Vol.18 No.2

        N/A Objectives : It has been demonstrated that oxidative stress of oxygen radicals is involved in vascular disorder. The aim of this study was to evaluate the cytotoxicity of glucose oxidase (GO) and protective effect of herb extract on GO-induced cytotoxicity in the cultured vascular endotherial cell (VEC) of mouse. Methods : Cytotoxic effect of GO and protective effect of Benincasae Semen (BS) were performed by MTT assay, after cultured VEC were incubated in the media containing 1-30 mU/ml GO for 6 hours. Results : GO decreased cell viability in dose-and time-dependent mannner, and BS increased cell viability decreased by GO-induced cytotoxicity in these cultures. Conclusion : From above the results, GO has cytotoxic effect, and herb extract, BS is very effective in blocking GO-induced cytotoxicity in cultured VEC.

      • KCI등재

        Glucose Oxidase가 척수지각신경절세포에 미치는 영향과 천마의 효과에 관한 연구

        송호준,이용석,손영우,이강,정종,신민교,홍기연 대한본초학회 2002 大韓本草學會誌 Vol.17 No.2

        Objectives : To clarify the cytotoxic effect of glucose oxidase(GO) and protective effect of gastrodiae Rhizoma (GR) on spinal sensory ganglion(DRG) neurons, neurotoxicity mediated by GO was measured by MTT assay and neurofilament enzymeimmuno assay(EIA). Methods : DRG neurons were cultured in the media containing various concentrations of GO for 3 hours. In addition, neuroprotective effects of GR, on GO-induced neurotoxicity in DRG neurons were examined after DRG neurons were preincubated with various concentrations of GR for 2 hours before 15mU/ml GO for 3 hours. Results : GO decreased remarkably cell viability in dependently in these cultures, and also RG increased cell viability and amount of neurofilament in DRG neurons damaged by GO. Conclusion : It is suggested that GO has toxic effect in cultured mouse DRG neurons, and also RG was effective in the protection of GO-induced neurotoxicity in these cultures.

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