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Kefir 및 Yoghurt 에서 분리된 Lactobacillus spp. 와 Non - starter 균주에 의한 돌연변이억제 ( 항암 ) 활성
윤영호(Y . H . Yoon),조중근(J . K . Cho),백영진(Y . J . Baek),허철성(C . S . Huh) 한국축산학회 1999 한국축산학회지 Vol.41 No.1
The antimutagenic activities of Lactobacillus spp. isolated from European kefir and yoghurt and those of non starter Lactobacillus and Bifidobaterium strains against 2-Nitrofluorene were studied by Ames test utilizing Salmonella typhimurium TA 98 to investigate probiotic effects of the strains. The optimal concentration of mutagen 2-nitrofluorene to produce 3,000 revertant colonies per plate turned out to be 10 ㎍/plate. Thirty six strains out of forty Lactobacillus spp. strains isolated from European kefir and yoghurt revealed antimutagenic activity and L. plantarum CU 722 showed the strongest antimutagenic activity of 50.34%. The antimutagenicity of non starter Lactobacillus and Brfidobacterium strains resulted in average 15% and 20% of mutation inhibition rate respectively. The effect of S-9 mix addition on the antimutagenicity rate against 2-Nitrofluorene was species and strain dependent.