녹차추출물인 (-)-epigallocatechin-3-gallate와 polyphenol이 배양 인체 각질형성세포, 인체 유표피암세포, 섬유모세포, 멜라닌세포, 및 혈관 내피세포의 증식에 미치는 영향

최재영 ( Jae Young Choi ),김경달 ( Kyung Dal Kim ),박재경 ( Jai Kyoung Park ),김낙인 ( Nack In Kim ) 대한피부과학회 2002 대한피부과학회지 Vol.40 No.4

N/A It is known that skin diseases ar related to proliferation of cellular components. Green tea has m a v favorable biologic effects: anti-inflammatory, antibacterial. antiviral effects. lowering of plasma cholesterol and triglyadde levels, reduction of blood pressure and platelet aggregation, antimuragenic, and anticarcinogenic activities. The effects of green tea on various cells in skin has been reported in previous studies; For keratinocytes and hmnan epidermoid carcinoma cells, green tea induces apoptosis only in cells, but no keratinocytes. For endothelial cells, green tea inhibits endothelial cell proliferation cancer melanocytes and fibroblast, it is little known. We investigated the effects of green tea polyphenol(GTP) and the major constituents, (-)-epieallocatechin-3-gallate(EGCG) on the proliferation in the cultured human keratinocytes, fibroblasts, melanocytes, endothelial cells and human epidermoid carcinoma cells(A431 cells). The prolifertive response was studied by the cell count and the uptake of vitiated thymidine after 48 hours of treatment. And we also observed apoposs using TUNEL staining. The results were as follows; Number of living cells were significantly decreased(p<0,05) in cultured human epidermal cells, melanocytes, fibroblasts, endothelial cells and A431 cells treated with different concentration of GTP and EGCG for 48 hours. The cells were decreased dose dependently as increase of concentration of the extracts. The [3H]thymidine incorporation w significantly decreased(p<0.05) in cultured human epidermal cells, melanocytes, fibroblasts, endothelial cells and A431 cells treated with different concentration of GTP and EGCG for 48 hours. The dose dependent inhibition was also seen in [^3H]thymidine incorporation by green tea extracts. Cell proliferation was significantly more inhibited(p<0.05) by EGCG compared to GTP in the same concentration. We

볼밀링에서 볼 배합비 선택을 위한 혼합물 실험계획 및 분석

김성준 ( Seong Jun Kim ),최재영 ( Jai Young Choi ),신현호 ( Hyun Ho Shin ) 한국품질경영학회 2014 품질경영학회지 Vol.42 No.4

Purpose: Ball milling is a popular process for obtaining fine powders in the part and material industry. One of important issues in the ball milling is to produce particles with a uniform size. Although many factors affect uniformity of particles, this paper focuses on the choice of ball diameter. Consider a ball milling where balls can be taken with three different diameters. The purpose of this paper is to find a ball mix which minimizes the average particle size. Methods: Ball diameters are selected as 10mm, 3mm, and 0.5mm. In order to find an optimum mixing ratio, the method of mixture experiments is employed in this paper. Taguchi``s signal-to-noise ratio (SNR) for smaller- the-better type is also used to analyze experimental data. Results: According to the experimental result, SNR is maximized when the ball mix is taken as either 7:3:0 or 6:4:0. Such mixing ratios can be technically validated in terms of porosity reduction. Conclusion: The ball mixing technique presented in this paper provides a useful way to improve the production efficiency with a low cost.

폴리드나바이러스(CpBV) 유래 면역억제 유전자를 이용한 베큘로바이러스 병원력 제고 기술

김용균(Kim Yonggyun),권보원(Bowon Kwon),배성우(Sungwoo Bae),최재영(Jai Young Choi),제연호(Yeon Ho Je) 한국농약과학회 2008 농약과학회지 Vol.12 No.3

경주지역의 옛마을 지명과 연관된 식물의 실태조사 연구

최재영 경주대학교 건설환경연구소 1999 建設環境論叢 Vol.- No.1

Our ancestors lived in this land, keeping faith with nature. And our culture is greatly related to the natural environment of our country. But today, old geographical names which have their own history are disappearing in this land because of unbanization and industrialization. Accordingly, it is very meaningful to study the ways of living, the geographical features, the use of trees, and the types of natural landscape object revealed in the orings of the old geographical names, and to exploit the result of this study is as follows: 1. Old geographical names are discovered more in the suburbs of Kyongju City than in the heart of this city. Especially, Yangbuk-meon area in the outskirts of Kyongju City has many old geographical names originating from its natural landscape objects. 2. Of the 557 old geographical names, 100 ones(18%) derived from the trees, the woods, and the plants in the areas concerned. 3. Some old geographical names derived from plants such as Pinus densiflora S. et Z., Prunus armeniaca var. ansu Max., Zizyphus jujuba var. inermis Rehder, Castanea crenata s. et Z, Lespedeza bicolor Turcz, Phyllostachys bambusoides S. et Z, Diospyros kaki Thunb, Celtis sinensis Pers, Paulownia coreana, Actinidia arguta Planch, Sophra japonica L, Quercus acutissima Carruthers, Rhus verniciflua Stokes Marsh, Pyrus pyrifolia Nakai, Ailanthus altissima Swingle, Cydonia sinensis Thouin, Broussonetia Kazinoki Siebold, Prunus armeniaca var. ansu Max

경주의 문화ㆍ관광도시 활성화를 위한 도시경관의 개선방안에 관한 연구

최재영 경주대학교 1997 論文集 Vol.9 No.-

도시는 경제적ㆍ사회적ㆍ문화적ㆍ환경적인 문제들이 종합적으로 고려되었을 때 쾌적한 생활을 누릴 수 있는 터전이 될 수 있다. 그러나 현재 우리의 생활이 이루어지고 있는 도시는 종합적 고려가 결여된 도시개발과 일관성 없는 건축활동으로 인해 혼란스러운 경관을 갖게 되었다. 경제성 위주의 개발로 인해 자연환경이 파괴되고 공해나 수질오염 등의 환경문제가 심각해지자 환경영향평가제도를 시행하여 개발에 의한 환경파괴를 막으려는 시도가 이루어졌으나, 생활의 질과 관계되는 도시환경의 경관적 측면에 대한 고려는 여전히 부족한 상황이다. 고도 경주는 70년대 들어서면서부터 정부의 ‘경주관광종합개발 10개년 계획’의 일환으로 근대적인 관광 도시로의 탈바꿈과 주변도시의 공업화에 따른 급격한 산업화로 인하여 현대 도시화를 촉진시켰고, 이 도시화는 당연히 고도의 역사경관 보존과 마찰을 가져오게 되었다. 경주관광종합개발계획은 1972년부터 1981년까지 10년에 걸쳐 의욕적으로 걸쳐 추진되었다. 당시의 추진된 보문관광지구개발, 사적지구정비 및 관광기반시설사업은 시외곽지 개발에만 치중하고 도심부는 각종 규제로 장기간 제한함과 동시에 개발가능지역은 경주만이 가지는 고유의 자연경관과 도시경관의 측면을 무시한 채 개발행위가 이루어짐에 따라 도시는 점점 기형적인 형태로 도시성장이 이루어져 오늘날과 같은 문화유적이 산재한 현대도시로 탈바꿈해 가고 있는 실정이다. 이러한 시점에서 경주의 시가지를 고도의 이미지에 부합되게 또 도시민의 쾌적한 삶의 공간조성을 위해서는 많은 연구가 필요하게 되었다. 본 연구의 목적은 경주의 시가지를 도시경관 차원에서 고도의 이미지를 제고하고 도시경관의 질을 높이기 위하여 개선해야 할 방안을 제시함으로서 문화관광도시로서의 면모를 새롭게 하고 관광의 활성화를 꽤하는데 그 목적이 있다. 또한 본 연구의 결과를 바탕으로하여 바람직한 세계적인 문화ㆍ관광도시 조성을 위한 재정비사업에 일조를 하고자 한다. 시민들에게 가로는 각 개인의 삶과 역사를 담을 만한 공간이어야 한다. 가로와 인간의 관계, 또는 그 가로경관을 무대로 한 사람들간의 접촉에서 생기는 정신적 충족감이나 쾌적함은 삶을 지탱하고 역사를 만들어 가는 과정이라 할 수 있다. 더구나 경주는 세계적인 문화ㆍ관광도시로서 국내외의 많은 관광객들이 찾고 있어 시가지의 가로경관은 문화유적과 더불어 중요한 관광자원이라고 할 수 있다. 그러나 경주의 가로경관은 본론에서 지적한 바와 같이 여러 가지 문제점을 안고 있다. 이러한 문제점에 대한 개선방안을 토대로 보다 쾌적하고 고도의 이미지를 높여줄 수 있는 가로경관의 정비가 뒤따라야 할 것이다. 도시의 좋은 가로경관, 수목이나 녹지, 도시인이 마음놓고 거닐 수 있는 쾌적한 공간등 좋은 것을 적극적으로 평가하여 그것을 보전할 뿐만 아니라 확대 재생산하는 장기적인 종합계획을 마련해야 할 것이다. 또한 이렇게 가로경관이 개선되고 정비됨으로서 도시환경의 질적 수준이 높아지고 문화ㆍ관광도시로서의 면모를 새롭게 하며, 더 나아가 천년 고도의 이미지를 역사경관과 함께 한층 더 높일 수 있을 것이다. Design and management furnishings for pedestrain area should be approached in the context of both the comprehensive of the pedestrian and specific steets where the furnishings are to be used. The review of general studies and methodology of design and management was carried out to obtain this purpose. For the better street environment by furnishing the pedestrian area, following alternative measuree are proposed. The related laws and regulations should be reinforced to offer a for reorganization of management system. To formulate a well organized management system, reconcillation between public administration and private is required. Establishing a standardized program for street furniture planning is the most important matter requiring immediate attetion. The program will be better if it has well organized hierarchial structure. The situations of urban street trees were examind through field survey in Kyongju City. Further experimental reserch results were analyzed and discussed in terms of the injury to urban street trees. The purpose of this to provide the basic guideline for the effective management of the urban street trees. The total number of the urban street trees in Kyongjiu city is 25,734 and the number of these treew is 15. Being widest scatterd, Ginkgo biloba occupies 68.2% of the urban street trees together with Prunus serrulata in the second place. The resurts of this study will contribute to the effective maintenance of urbanscape image for the heightening of image of tourist-oriented cities.

경주의 역사문화도시 이미지 제고를 위한 문화공간·시설의 조성방안에 관한 연구

최재영 경주대학교 지역개발연구소 2000 地域開發論叢 Vol.- No.3

The study aims to offer some proposals. for improvement in the image of Kyongju City, as the amcient Kingdom Silla's Capital and as one of the most gistorical and cultural cities in Korea. This study puts stress on the reformation of the city into a most cultural space. Some proposals can be made as follows: 1. To utilize the Kyongju Cultural Center(former Kyongju National Museum)as a folk museum. 2. To reconstruct the historical site of the commercial business district as a cultural space. 3. To revitalize the culture and arts streets of the city. 4. To build a complex culture and arts center for the city. 5. To set the urban street spaces in good condition. 6. To utilize the urban rivers as cultural spaces. 7. To set the open spaces of the city in good condition. 8. To build a new unigied city hall. 9. To hold culture and ares festivats successfully. 10. To ask for help from the Korean government. When these proposals have been put to practice, kyongju City will be born again as the most historical and cultural city in which the past, the present and the future will coexist, and people can feel the breath of the past of the most brilliant Silla Kingdom.

학교의 교목(校木)·교화(校花)에 대한 실태조사 연구 : 포항지역 초·중·고등학교를 대상으로 The case of Elementary·Middle·High Schools in Phohang

최재영 경주대학교 2004 論文集 Vol.17 No.-

This paper aims to survey and analyse the cases of 117 ElementaryㆍMiddleㆍHigh Schools of a School Trees and Flowers situation in Phohang. The result of the study are as follows; 1. Species of a School Trees are 11 and Flowers are 16 of total Schools in Phohang. 2. Juniperus chines were designated more freqently than others were, concerned with the quantity, and Pinus dens flora, Ginkgo biloba, Cedrus deodara, Zelkoua serrata, Pinus thunbergii, Platanus occidentalis, Chionanthus retusa, Euonymus japonica, Abies holophylla, Taxes cuspidata are followed in order. 3. Rosa hybrid were designated more freqently than others were, concerned with the quantity, and Forsythia koreana, Lilium longiflorum, Prunus mume, Lagerstroemi indica, Camellia spp., Rhododendron schlippenbachii, Rhododendron lateritium, Chrysanthemum morifolium, Syringa vulgaris, Punica granatwn, Lilium longiflorum, Chrysanthemum zawadskii, Narcissus tazetta, Pyrus pyrifolia, Chionanthus retusa are followed in order. 4. Native Species are 17 with 63.0%, Alien Species are 10 with 37.0%. Native Species are planted more than Alien Species are.

경주지역의 옛지명 유래(由來)에 나타나는 자연경관대상물 유형(類型)에 관한 연구

최재영 경주대학교 1998 論文集 Vol.10 No.-

Our ancestors lived in this land, keeping faith with nature. And our culture is greatly related to the natural environment of our country. But today, old geographical names which have their own history are disappearing in this land because of urbanization and industrialization. Accordingly, it is very meaningful to study the ways of living, the geographical features, the use of trees, and the types of natural landscape object revealed in the origins of the old geographical names, and to exploit the result of this study in the field of landscape architecture for the modern life. And the result of this study is as follows : 1. 26 natural landscape objects and 800 old geographical names are discovered at 55 areas or villages of Kyongju area. And 557 old geographical names derived from the natural landscape objects in the areas concerned. 2. Old geographical names are discovered more in the suburbs of Kyongju City than in the heart of this city. Especially, Oedong-eup area in the outskirts of Kyongju City has many old geographical names originating from its natural landscape objects. 3. Old geographical names derived from the location, the geographical features, the trees, the plants, the buildings, the rivers, the valleys, the ponds, the temples and the rocks in the areas concerned, in the order of frequency. 4. Of the 557 old geographical names, 103 ones(18%) derived from the trees, the woods, and the plants in the areas concerned. 5. Some old geographical names derived from plants such as Pinus densiflora S. et Z., Prunus armeniaca var. ansu Max., zizyphus jujuba var. inermis Rehder, Castanea crenata S. et Z, Lespedeza bicolor Turcz, Phyllostachys bambusoides S. et Z, Diospyros kaki Thunb, Celtis sinensis Pers, Paulownia coreana, Actinidia arguta Planch, Sophra japonica L, Quercus acutissima Carruthers, Rhus verniciflua Stokes Marsh, Pyrus pyrifolia Nakai, Ailanthus altissima Swingle, Cydonia sinensis Thouin, Broussonetia Kazinoki Siebold, Prunus armeniaca var ansu Max

경주시 가로수 현황과 개선방안에 관한 연구

최재영 慶州大學校 2005 論文集 Vol.18 No.1

The situations of urban street trees were examind through field survey in Gyeong-Ju City. Further experimental research results were analyzed and discussed in terms of the injury to urban street trees. The purpose of this study is to provide the basic guideline for the effective management of the urban street trees. The total number of the urban street trees in Gyeong-Ju city is 25,570 and the number of these trees is 14. Being widest scatterd, Prunus serrulata 68.2% of the urban street trees together with Ginkgo biloba in the second place. Injury to the trunk of urban street trees is the worst at the street of the elementary school and the most crowded street. Most of the injuries is hurt by nails or sharp knives and 60% of the total urban street trees is injuried by human activities.

경주보문관광단지 조경대상물의 이용후 평가에 관한 연구

최재영 경주대학교 1996 論文集 Vol.8 No.-

As Kyongju is one of world-famous tourist cities that have cultural remains appoted by UNESCO, its redevelopment is inevitable in accordance with the tourists' rapid demand. First of all, which a view to offering the fundamental data for that project, it is urgent to evaluate landscape objects tourist's having used them. After evaluating landscape architectural objects of Bomoon Tourism site, this study shows the improvementplan about the evaluation result as below. First, most space must be prepared more comfortably than before in order to strengthen some merits as tourism site. Second, a tall tree or a symbol of Bomoon site must be established to fortify the character of land mark in the node of line of flow. Third, street trees must be uniform to give the symbolism of Bomoon site as beautiful native sorts of trees. Fourth, the establishment of landscape architectural objects must be considered if those objects can function fully as well as harmonize with the desirable image of Bomoon site. Fifth, a promenades must be constructed so as to be safe for even the handicapped. Sixth, the ever security of water resource for Bomoon lake must be master planned to create the lake side alive. The result of this study is to contribute to the fundamental data which can help effective redevelopment as well as practical management of Bomoon tourism site.