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RISS 인기검색어
- 검색키워드
- 저자 : 조용숙 ( Yong Suk Jo ) (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
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조용숙 ( Yong Suk Jo ),배원 ( Won Bae ),김주혜 ( Joo Hae Kim ),이하연 ( Ha Youn Lee ),곽낙원 ( Nak Won Kwak ),고성준 ( Sung Jun Ko ),이창훈 ( Chang Hoon Lee ) 대한내과학회 2015 대한내과학회지 Vol.88 No.2
The most common site of extrahepatic metastasis in cases of advanced hepatocellular carcinoma is the lung. A 60-year-old Korean male had been previously diagnosed with hepatocellular carcinoma and was treated several times with transcatheter arterial chemoembolization prior to a regime of sorafenib after multiple bone metastases were detected. Despite 2 months of systemic treatment, the disease progressed, and newly developed cavitary nodules and ground glass opacities were observed on a chest computed tomography scan. Initially the patient was diagnosed with septic pneumonia and was subsequently treated with antibiotics over 2 weeks, with no observable improvement. A percutaneous transthoracic needle aspiration biopsy was performed to ascertain the noninfectious origin of the lung lesions. As a result, a rare form of pulmonary metastasis from hepatocellular carcinoma was discovered. Unfortunately, there were no available treatment options for the patient and so end-of-life care was recommended. (Korean J Med 2015;88:202-206)
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증례 : 내분비-대사 ; 그레이브스병에서 메티마졸 투여 후 발생한 무과립구증과 급성충수염
홍아람 ( A Ram Hong ),박경선 ( Kyeong Seon Park ),조용숙 ( Yong Suk Jo ),박도준 ( Do Joon Park ),박영주 ( Young Joo Park ),김정희 ( Jung Hee Kim ) 대한내과학회 2014 대한내과학회지 Vol.86 No.2
무과립구증은 메티마졸을 복용하는 환자에서 드물게 발생하나 치명적인 부작용으로서 대부분 상기도 감염의 형태로 발현한다. 그레이브스병으로 메티마졸을 복용하던 환자에서 무과립구증이 급성충수염으로 발현한 증례는 보고된 바 없다. 본 저자들은 그레이브스병으로 메티마졸을 복용하던 중 발생한 무과립구증이 드물게 급성충수염으로 발현한 환자에서 적절한 내과적 치료 및 수술적 치료 후 양호한 경과를 확인하였기에 문헌고찰과 함께 보고하는 바이다. Agranulocytosis is a rare, but life-threatening, adverse effect of methimazole, which usually manifests as an upper respiratory infection. Agranulocytosis together with acute appendicitis is especially rare in patients with Graves` disease taking methimazole. A 44-year-old woman presented to our hospital with abdominal pain and a fever. She had been taking methimazole and propranolol for Graves` disease for the previous 8 weeks. Her symptoms were compatible with acute appendicitis. Computed tomography of the abdomen revealed acute appendicitis with impending rupture. However, the circulating absolute neutrophil count was 10/mm3. We managed her with antibiotics and granulocyte colony stimulating factor rather than with emergency surgery. The thyrotoxicosis was treated with intravenous contrast medium while fasting, followed by Lugol`s solution and lithium. After recovering from the neutropenia, she underwent a total thyroidectomy combined with an appendectomy. Here, we report a patient with Graves` disease who developed methimazole-induced agranulocytosis presenting as acute appendicitis. (Korean J Med 2014;86:232-236)
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