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자폐스펙트럼장애 환자에서의 인지적 공감 및 정서적 공감의 신경 상관물
정승원(Seungwon Chung),손정우(Jung-Woo Son),이승복(Seungbok Lee),김혜리(Hei-Rhee Ghim),이상익(Sang-Ick Lee),신철진(Chul-Jin Shin),김시경(Siekyeong Kim),주가원(Gawon Ju),최상철(Sang Cheol Choi),김양렬(Yang Yeol Kim),구영진(Young Jin K 대한소아청소년정신의학회 2016 소아청소년정신의학 Vol.27 No.3
Objectives: Individuals with autism spectrum disorder (ASD) are considered to have problems with empathy. It has recently been suggested that there are two systems for empathy; cognitive and emotional. We aimed to investigate the neural response to cognitive and emotional empathy and elucidate the neurobiological aspects of empathy in patients with ASD. Methods: We recruited patients with ASD (N=17, ASD group) and healthy controls (HC) (N=22, HC group) for an functional magnetic resonance imaging study. All of the subjects were scanned while performing cognitive and emotional empathy tasks. The differences in brain activation between the groups were assessed by contrasting their neural activity during the tasks. Results: During both tasks, the ASD group showed greater neural activities in the bilateral occipital area compared to the HC group. The ASD group showed more activation in the bilateral precunei only during the emotional empathy task. No brain regions were more activated in the HC group than in the ASD group during the cognitive empathy task. While performing the emotional empathy task, the HC group exhibited greater neural activities in the left middle frontal gyrus and right anterior cingulate gyrus than the ASD group. Conclusion: This study showed that the brain regions associated with cognitive and emotional empathy in ASD patients differed from those in healthy individuals. The results of this study suggest that individuals with ASD might have defects both in cognitive empathy and in emotional empathy.
단순화한 프레셋 거리를 이용한 적대적 생성 신경망의 모드 드롭 및 붕괴 검출 기법
김충일(Chung-Il Kim),정승원(Seungwon Jung),문지훈(Jihoon Moon),황인준(Eenjun Hwang) Korean Institute of Information Scientists and Eng 2019 정보과학회논문지 Vol.46 No.10
Even though generative adversarial network (GAN) is an excellent model for generating data based on the estimation of real data distribution by of two adversarial learning network, this model often suffers from mode drop that does not learn distribution during learning, or mode collapse that generates only one or very few distribution samples. Most studies to detect these problems have used well-balanced data or additional neural network models. In this paper, we propose a method to detect mode drop and collapse by using a simplified Frèchet distance, which does not require any additional model or well-balanced data. Through various experiments, we showed that our proposed distance metric detected mode drop and collapse more accurately than any other metrics used in GANs.
이정환(Jeonghwan Lee),정승원(Seungwon Chung),박혜미(Hyemi Park),주가원(Gawon Ju),손정우(Jung-Woo Son),신철진(Chul-Jin Shin),이상익(Sang Ick Lee),김시경(Siekyeong Kim) 대한생물치료정신의학회 2020 생물치료정신의학 Vol.26 No.3
Objectives:Chronic alcohol ingestion is associated with structural alterations in the brain. In patients with alcohol dependence, thalamic volume is frequently diminished, commensurate with the amount of alcohol consumption, duration of illness, and cognitive impairment. Since the thalamus is composed of histologically and functionally distinct nuclei, we aimed to investigate volumetric changes of these nuclei in patients with alcohol dependence. Methods:Twenty-three participants with alcohol dependence who had abstained from drinking for at least 3 months (alcohol group) and 21 age-matched healthy controls (control group) underwent 3T magnetic resonance imaging. The volumes of 50 individual thalamic nuclei were reconstructed using FreeSurfer 6.0.0. We compared normalized volumes of thalamic nuclei between the two groups using analysis of covariance, controlling for age. The p-values were corrected using False Discovery Rate (p<0.05). Results:The alcohol group demonstrated atrophy of the whole thalamus and nuclei in the anterior, ventral, intralaminar, and medial thalamus. However, the volumes of bilateral lateral geniculate, medial geniculate, suprageniculatelimitans, pulvinar lateral, and right pulvinar inferior nuclei which are included in posterior thalamus, were not significantly different between the two groups. Conclusion:In the alcohol group, atrophy of most thalamic nuclei which are associated with language processing, visuospatial memory, autobiographical memory, executive function and attention were not normalized after 3 months of sobriety. Furthermore, thalamic nuclei volumes, which are associated with visual and auditory information processing, were not significantly different compared to controls. We suggest that this could be microstructural evidence of relatively preserved visual attention and auditory startle response in patients with alcohol dependence.
박경인(Park, Kyungin),정승원(Chung, Seungwon),신안나(Shin, Anna) 한국청소년정책연구원 2013 한국청소년연구 Vol.24 No.2
이 연구는 한국 아동?청소년패널조사 1, 2차년도 자료의 초등학교 4학년과 중학교 1학년 패널의 응답 자료를 대상으로, 부모 양육태도의 대표적 프로파일을 탐색적으로 분석하고, 부모의 양육태도와 학교 적응 및 학업성취도라는 교육 변인과의 관계를 살펴보았다. 이를 위해 다차원척도법을 사용하여 대표적 프로파일을 추출하고, 이를 토대로 프로파일 유형과 교육 변인 간의 관계를 분석하였다. 연구 결과는 다음과 같다. 첫째, 초등학교 4학년 패널과 중학교 1학년 패널의 부모 양육태도에 대한 대표 프로파일을 분석 결과, ‘합리-애정형’, ‘방임형’, ‘학대형’의 세 가지 차원이 도출되었다. 둘째, 합리-애정형 프로파일의 유사성 지수는 학교 적응 및 학업성취도와 유의한 정적 상관을 보였고, 방임형 프로파일은 유의한 부적 상관을 보였다. 학대형의 경우에는 중학생의 학업성취도와 유의한 부적 상관이 있었다. 셋째, 성별과 학업성취 수준에 따라 그룹을 나누어 분석한 결과, 남녀 간 개인 모수 차이는 통계적으로 유의하였으며, 학업성취도가 높은 집단일수록 부모 양육태도의 평균 척도점수가 합리-애정형 프로파일에 가깝게 나타났다. 이 연구는 부모의 양육태도를 하위영역 별로 구분하지 않고, 전체적인 연속선상에서 양육태도의 양상을 살펴보았다는 점에서 특히 의의가 있다. The purpose of this study was to analyze a number of representative profiles of parenting styles and to examine the relationship between profiles of parenting styles and educational variables including school adjustment and academic achievement using the 1st and 2nd year of Children Youth Panel Survey data. The results of this study are summarized as follows: First, three dimensions were extracted from the analysis of representative profiles of parenting styles: reasoning and affection, neglect, and physical abuse. Second, similarity indices of reasoning and affection profile were positively related to school adjustment and academic achievement in both elementary and middle school panels, while those of the neglect profile were negatively related to school adjustment and academic achievement in both panels. In addition, the similarity indices of the physical abuse profile were negatively related to academic achievement in the middle school panel. Third, the differences among the observed groups, which can be divided according to gender and level of achievement were examined in greater depth. The results from group analysis indicate that the parametric differences between males and females were statistically significant and the mean scale scores of parenting styles for the high achievement students group were similar to the reasoning and affection profile. This study is significant in that it analyzes parenting styles as a whole concept while other previous studies have tended to focus on sub domains.