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환자의 재현성을 위한 고정장치(Vac-lok) 제작과 방사선치료에서 유용성 평가
이재승,김경희,정규환,권대철,구은회,박철우,임인철,동경래,정운관,Lee, Jae-Seung,Kim, Gyoung-Hee,Jeong, Kyu-Hwan,Kweon, Dae-Cheol,Goo, Eun-Hoe,Park, Cheol-Woo,Im, In-Chul,Dong, Kyung-Rae,Chung, Woon-Kwan 대한방사선방어학회 2011 방사선방어학회지 Vol.36 No.1
방사선치료에서 특수한 체형을 갖거나 특별한 자세가 요구되는 환자에게 적용할 수 있으며 환자의 위치결정 및 조사영역 내에서 표적체적의 위치 재현성을 향상시킬 수 있는 고정 장치(Vac-lok)를 제작하고 그 유용성을 검증하였다. EVA 합성수지와 1.5 mm 바이오 비드폼을 이용하여 제작된 Vac-lok의 기능적, 형태적 검사를 시행하고 모형 및 환자의 상대적 재현성을 분석하였다. 전 방사선치료 기간 동안 제작된 Vac-lok의 기능적 검사에서 미소한 진공 압력의 변화는 있었으나 무시할 정도로 작았다. 모형의 상대적 재현성은 기존 상품화된 제품보다 재현성이 향상되었으며 평균 4% 미만의 오차를 보였다. 또한 환자의 상대적 재현성에서 전후 또는 측면방향에서 다소 오차가 증가하였으나 최대 ${\pm}\;2.3$ mm 미만이었다. 결론적으로 방사선치료의 한계 오차를 ${\pm}\;3$ mm 미만이라 할 때 임상적으로 충분하게 사용 가능하였고 재현성의 향상과 특수한 환자에게 맞춤형 고정 장치를 가격이 저렴하면서 신속하게 제공할 수 있을 것으로 사료된다. We manufactured the Vac-lok that can be applied to patient of special body shape and need to special set-up position and evaluated the usefulness in the radiation therapy. The manufacture Vac-lok, It was used EVA resin and biobeadform of a diameter 1.5 mm. carried out the test of functionality, structural and analyzed the relative reproducibility of phantoms and patients. During the total period of radiation therapy, Vacuum pressure bring variety to a very small amount in the test of functionality of the manufacture Vac-lok. But It was a negligible quantity. The manufacture Vac-lok improved the relative reproducibility of phantoms than the existing Vac-lok and tolerance has a confidence less than 4% error. Also, relative reproducibility of patient increased error than phantom in the antero-posterior and lateral plan. However, the maximum set-up error was less than ${\pm}\;2.3$ mm. In conclusion, If tolerance set-up error of radiotherapy is less than ${\pm}\;3$ mm, the manufacture Vac-lok was enough possible to use and improvement of reproducibility, considering supply with the Vac-lok made to measure of special patient that produced at a low price and without delay.
GM 고추의 환경위해성 평가 프로토콜 작성을 위한 농업적 형질 분석
조동욱 ( Dong Wook Cho ),정규환 ( Kyu Hwan Chung ) 한국환경과학회 2011 한국환경과학회지 Vol.20 No.9
This study was aimed to establish the evaluating protocol and standard assessment for genetically modified (GM) hot pepper and to find out a proper statistic method to analyze for equality of agricultural characters between GM and non-GM pepper lines. GM and non-GM hot pepper lines were cultivated in two GMO fields in the middle region of Korea and total of 52 agricultural characters were collected during the plant growing season for 4 years, 2007 to 2010. Levene`s test was conducted to confirm the homogeneity of raw data before statistic analysis. Two-way ANOVA in the multivariate tests and t-test were conducted to analyze 52 agricultural characters in order to find out the equality between H15 and P2377. From the statistical analysis through two-way ANOVA, 16 out of 16 plant growth traits, 9 out of 18 green fruit traits and 7 out of 18 red fruit traits among 4 years and 9 out of 16 plant growth traits, 4 out of 18 green fruit traits and 3 out of 18 red fruit traits between H15 and P2377 have shown the statistic differences. With the same raw data of 52 agricultural characters, t-test was also conducted. Based on the result from t-test, only 1 out of 16 plant growth traits, 2 out of 18 green fruit traits and 1 out of 18 red fruit traits have shown the differences between H15 and P2377, so that it was concluded that there is no statistic difference between H15 and P2377 in terms of agricultural characters. Also, the t-test is a proper statistic method to analyze each trait between GM and its control lines in order to evaluate agricultural characters.
임순성(Soon Sung Lim),이연실(Yeon Sil Lee),한샘(Saem Han),정규환(Kyu Hwan Chung),이상현(Sanghyun Lee),신국현(Kuk Hyun Shin) 한국원예학회 2008 원예과학기술지 Vol.26 No.4
오미자나무로부터 산업적 용도를 찾고자 정유성분을 GC와 GC/MS의 분석법에따라 분석하였다. 오미자나무의 줄기에는 α-pinene(7.46%), β-pinene(30.66%), 1,8-cineole(4.81%), 4-methyl-1-(1-methylethyl)-3-cyclohexene-1-ol(7.90%) 등의 성분함량이 높았고, 오미자나무 뿌리에는 camphene(10.05%), β-pinene(17.67%), sabinene(4.02%), l-limonene(4.04%), 1-methyl-4-(1-methylethyl)benzene(4.97%), linalyl acetate(7.86%), linalool oxide(4.84%) 등의 성분함량이 높았다. 자생 오미자나무 줄기 및 뿌리에 공통적으로 β-pinene의 정유성분이 함유되어 있었으며, 오미자나무 줄기 및 뿌리의 향기특성을 이용한 산업화가 가능하다고 본다. To search for the new development of industrial application, chemical analysis of volatile constituents from native Schizandra chinensis was conducted by GC and GC/MS spectrometric analyses. The chemical composition of the volatile constituents from S. chinensis was confirmed by the aid of Wiley/NBS Library and RI indice searches. The major constituents were α-pinene (7.46%), β-pinene (30.66%), 1,8-cineole (4.81%), and 4-methyl-1-(1-methylethyl)-3-cyclohexene-1-ol (7.90%) from the stems, and camphene (10.05%), β-pinene (17.67%), sabinene (4.02%), l-limonene (4.04%), 1-methyl-4-(1-methylethyl)benzene (4.97%), linalyl acetate (7.86%), and linalool oxide (4.84%) from the roots. Among them, β-pinene is a major constituent in the stems and roots of native S. chinensis that presented possibilities for industrial applications.